MTMR2 (NM_201281) Human Untagged Clone

CAT#: SC111724

MTMR2 (untagged)-Human myotubularin related protein 2 (MTMR2), transcript variant 3

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MTMR2
• Synonyms: CMT4B; CMT4B1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC111724 sequence for NM_201281 edited (data generated by NextGen Sequencing)
  ATGGAAGAACCACCCTTGCTTCCAGGAGAAAATATTAAAGACATGGCCAAAGATGTAACT
  TATATATGTCCATTCACTGGCGCTGTACGAGGAACTCTGACTGTCACGAATTATAGGTTA
  TATTTCAAAAGCATGGAACGGGATCCCCCATTTGTTTTAGATGCTTCCCTTGGTGTGATA
  AATAGAGTAGAAAAAATTGGTGGTGCTTCTAGTCGAGGTGAAAATTCTTATGGACTAGAA
  ACTGTGTGTAAGGATATTAGGAATTTACGATTTGCTCATAAACCTGAGGGGCGGACAAGA
  AGATCCATATTTGAGAATCTAATGAAATATGCATTTCCTGTCTCTAATAACCTGCCTCTT
  TTTGCTTTTGAATACAAAGAAGTATTCCCTGAAAATGGGTGGAAGCTATATGACCCTCTT
  TTAGAGTATAGAAGGCAGGGAATTCCAAATGAAAGCTGGAGAATAACAAAGATAAATGAA
  CGATATGAACTTTGTGATACATACCCTGCCCTCCTGGTTGTGCCAGCAAATATTCCTGAT
  GAAGAATTAAAGAGAGTGGCATCCTTCAGATCAAGAGGCCGTATCCCAGTTTTATCATGG
  ATTCATCCTGAAAGTCAAGCCACAATCACTCGGTGTAGCCAGCCCATGGTTGGAGTGAGT
  GGAAAGCGAAGCAAAGAAGATGAAAAATACCTTCAAGCTATCATGGATTCCAATGCCCAG
  TCTCACAAAATCTTTATATTTGATGCCCGGCCAAGTGTTAATGCTGTTGCCAACAAGGCA
  AAGGGTGGAGGTTATGAAAGTGAAGATGCCTATCAAAATGCTGAACTAGTTTTCCTGGAT
  ATCCACAATATTCATGTTATGAGAGAATCATTACGAAAACTTAAGGAGATTGTGTACCCC
  AACATTGAGGAAACYCACTGGTTGTCTAACTTGGAATCTACTCATTGGCTAGAACATATT
  AAGCTTATTCTTGCAGGGGCTCTTAGGATTGCTGACAAGGTAGAGTCAGGGAAGACGTCT
  GTGGTAGTGCATTGCAGTGATGGTTGGGATCGCACAGCTCAGCTCACTTCCCTTGCCATG
  CTCATGTTGGATGGATACTATCGAACCATCCGAGGATTTGAAGTCCTTGTGGAGAAAGAA
  TGGCTAAGTTTTGGACATCGATTTCAACTAAGAGTTGGCCATGGAGATAAGAACCATGCA
  GATGCAGACAGATCGCCTGTTTTTCTTCAATTTATTGACTGTGTCTGGCAGATGACAAGA
  CAGTTTCCTACCGCATTTGAATTCAATGAGTATTTTCTCATTACCATTTTGGACCACCTA
  TACAGCTGCTTATTCGGAACATTCCTCTGTAATAGTGAACAACAGAGAGGAAAAGAGAAT
  CTTCCTAAAAGGACTGTGTCACTGTGGTCTTACATAAACAGCCAGCTGGAAGACTTCACT
  AATCCTCTCTATGGGAGCTATTCCAATCATGTCCTTTATCCAGTAGCCAGCATGCGCCAC
  CTAGAGCTCTGGGTGGGATATTACATAAGGTGGAATCCACGGATGAAACCACAGGAACCT
  ATTCACAACAGATACAAAGAACTTCTTGCTAAACGAGCAGAGCTTCAGAAAAAAGTAGAG
  GAACTACAGAGAGAGATTTCTAACCGATCAACCTCATCCTCAGAGAGAGCCAGCTCTCCT
  GCACAGTGTGTCACTCCTGTCCAAACTGTTGTATAA
  
  Clone variation with respect to NM_201281.2
  915 c=>y
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016156 unedited
  GGGTCANAATTTGTATACGACTCCTATAGGCGGCCGCGNAATTCGCACGAGGGCCGCTTC
  CGGTCTCCCTCCCGGGCCGGCGCTGGCCTGACTGCGGCCCCGGTCCGTAGCACTCCGCCC
  TCCGCTTCTCCCGCCCTGTAGCCGCGAAGACTGCTTCAGCCTTTCCCTGTGCTGCCCCTG
  CCGCGCGATGGAGAAGAGCTCGAGCTGCGAGAGTCTTGGCTCCCAGCCGGCGGCGGCTCG
  GCCGCCCAGCGTGGACTCCTTGTCCAGTGCCTCCACTTCTCATTCAGAGAATTCAGTGCA
  TACAAAATCAGCTTCTGTTGTATCATCAGATTCCATTTCAACTTCTGCCGACAACTTTTC
  TCCTGATTTGAGGGTCCTGAGGGAGTCTAACAAGTTAGCAGAAATGGAAGAACCACCCTT
  GCTTCCAGGAGAAAATATTAAAGACATGGCCAAAGATGTAACTTATATATGTCCATTCAC
  TGGCGCTGTACGAGGAACTCTGACTGTCACGAATTATAGGTTATATTTCAAAAGCATGGA
  ACGGGATCCCCCATTTGTTTTAGATGCTTCCCTTGGTGTGATAAATAGAGTAGAAAAAAT
  TGGTGGTGCTTCTAGTCGAGGTGAAAATTCTTATGGACTAGAAACTGTGTGTAAGGATAT
  TAGGAATTTACGATTTGCTCATAAACCTGAGGGGCGGACAAGAAGATCCATATTTGAGAA
  TCTAATGAAATATGCATTTCCTGTCTCTAATAACCTGCCTCTNTTTGCTTTTGAATACAA
  AGAAGTATTCCCTGAAAATGGGTGGAAGCTATATGACCCTCTTTTAGAGTATAGAAGGCA
  GGGAATTCCAAATGAAAGCTGGAGAATACCAAGATNAATGAACGATATGAACTTTGTGAT
  ACATACCCTGCCCTCCTGGNNTGTGCCAGCAATATTCCTGATGAAAN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016156 unedited
  TTAGCTTTGGACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAAAGTTAAAAAGCCAGGGGAAAATTTT
  TTTTAATTAAAAAACCAGGGGGACAAGAAACCTCCTTTGTTACAGCCCATTACAAAGGGC
  TCTTAGGGAAAAAAAAATAAACCTCAAAGCCAAGGGTTTTTACCACCCCCAAACTTTTAC
  TTGTAACAGGGGAACAGGGAACCAAAATTTTTTTTACGGGCTTTGAAATGGAAAAACATC
  TTTAACATGCAGGGGGTTTTTTGGAAAACTAAATCGTGGAGGGAAATTCCAAAATTTGCA
  AAGGAAAAAAATGTAAAATTGGACCCCAGGCCTTTTCACTATAACCTTTTTATCCAAAAT
  TCAAAAAAAAGGCCAACCCTAAAAAAATTTTAAAATCCTTCTTAAAAACTTGCTAATAAC
  CTTCGGGGGGTCCAAACCCCCAAAACAGGGGAAACACCCTGGAGAAAAAAATTAGTTTTA
  AAAATATCTTTCATGAGGTTTGGGGAAATGGGCCTAACCTGAAGGGCATGGAATTCTTTG
  AACTCCTGTAGGGATACTTTTCCCCCCTAAATTTCCCCCCAAGCCCATCTATAAGGCCCC
  CCATTTGGAACCAACCTGCTAATATGCCTAAAGTATGGAAAATATGGACCGCCAATAAAT
  TTCAACCTACCACCCCCCCGGAGTATCCTCCAACCCTTTGGCTTTTTACTTTATGAAAAA
  ATTTGGAGAGTTGAAAAGTGACCAAGGGAAACCCCCTCCCCGGGAAAAAAAAAACCCCTA
  AAGGGGAAAAGGGGTATTACAAAGATTTTGAACTGGCATGAAACAAGGGCCCAATTATGG
  GAAGCCCCCAGATTTCCGGGGTGGTTGAGAAACAGAGTTCCTTTGGCCAGGGAGCCCAGA
  GGGTTTTTAAAAAGTGTTAATAATACC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_201281
• ORF Size: 1716 bp
• Insert Size: 3370
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_201281.1, NP_958438.1
• RefSeq Size: 4565
• RefSeq ORF: 1716
• Locus ID: 8898
• Protein Families: Druggable Genome, Phosphatase
• Protein Pathways: Fructose and mannose metabolism, Metabolic pathways, Riboflavin metabolism, Thiamine metabolism
• Gene Summary: This gene is a member of the myotubularin family of phosphoinositide lipid phosphatases. The encoded protein possesses phosphatase activity towards phosphatidylinositol-3-phosphate and phosphatidylinositol-3,5-bisphosphate. Mutations in this gene are a cause of Charcot-Marie-Tooth disease type 4B, an autosomal recessive demyelinating neuropathy. Alternatively spliced transcript variants encoding multiple isoforms have been found for this gene. [provided by RefSeq, Aug 2011]
  Transcript Variant: This variant (3) includes an additional internal exon in its 5' UTR and initiates translation at a downstream start codon, compared to variant 1, resulting in an isoform (2) that is shorter at the N-terminus, compared to isoform 1. Variants 2, 3 and 4 encode the same isoform.