B7H4 (VTCN1) (NM_024626) Human Untagged Clone

CAT#: SC112129

VTCN1 (untagged)-Human V-set domain containing T cell activation inhibitor 1 (VTCN1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VTCN1
• Synonyms: B7-H4; B7h.5; B7H4; B7S1; B7X; PRO1291; VCTN1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_024626 edited
  GAATTCGGCACGAGGGGCAGCGGCAGCTCCACTCAGCCAGTACCCAGATACGCTGGGAAC
  CTTCCCCAGCCATGGCTTCCCTGGGGCAGATCCTCTTCTGGAGCATAATTAGCATCATCA
  TTATTCTGGCTGGAGCAATTGCACTCATCATTGGCTTTGGTATTTCAGGGAGACACTCCA
  TCACAGTCACTACTGTCGCCTCAGCTGGGAACATTGGGGAGGATGGAATCCTGAGCTGCA
  CTTTTGAACCTGACATCAAACTTTCTGATATCGTGATACAATGGCTGAAGGAAGGTGTTT
  TAGGCTTGGTCCATGAGTTCAAAGAAGGCAAAGATGAGCTGTCGGAGCAGGATGAAATGT
  TCAGAGGCCGGACAGCAGTGTTTGCTGATCAAGTGATAGTTGGCAATGCCTCTTTGCGGC
  TGAAAAACGTGCAACTCACAGATGCTGGCACCTACAAATGTTATATCATCACTTCTAAAG
  GCAAGGGGAATGCTAACCTTGAGTATAAAACTGGAGCCTTCAGCATGCCGGAAGTGAATG
  TGGACTATAATGCCAGCTCAGAGACCTTGCGGTGTGAGGCTCCCCGATGGTTCCCCCAGC
  CCACAGTGGTCTGGGCATCCCAAGTTGACCAGGGAGCCAACTTCTCGGAAGTCTCCAATA
  CCAGCTTTGAGCTGAACTCTGAGAATGTGACCATGAAGGTTGTGTCTGTGCTCTACAATG
  TTACGATCAACAACACATACTCCTGTATGATTGAAAATGACATTGCCAAAGCAACAGGGG
  ATATCAAAGTGACAGAATCGGAGATCAAAAGGCGGAGTCACCTACAGCTGCTAAACTCAA
  AGGCTTCTCTGTGTGTCTCTTCTTTCTTTGCCATCAGCTGGGCACTTCTGCCTCTCAGCC
  CTTACCTGATGCTAAAATAATGTGCCTCGGCCACAAAAAAGCATGCAAAGTCATTGTTAC
  AACAGGGATCTACAGAACTATTTCACCACCAGATATGACCTAGTTTTATATTTCTGGGAG
  GAAATGAATTCATATCTAGAAGTCTGGAGTGAGCAAACAAGAGCAAGAAACAAAAAGAAG
  CCAAAAGCAGAAGGCTCCAATATGAACAAGATAAATCTATCTTCAAAGACATATTAGAAG
  TTGGGAAAATAATTCATGTGAACTAGACAAGTGTGTTAAGAGTGATAAGTAAAATGCACG
  TGGAGACAAGTGCATCCCCAGATCTCAGGGACCTCCCCCTGCCTGTCACCTGGGGAGTGA
  GAGGACAGGATAGTGCATGTTCTTTGTCTCTGAATTTTTAGTTATATGTGCTGTAATGTT
  GCTCTGAGGAAGCCCCTGGAAAGTCTATCCCAACATATCCACATCTTATATTCCACAAAT
  TAAGCTGTAGTATGTACCCTAAGACGCTGCTAATTGACTGCCACTTCGCAACTCAGGGGC
  GGCTGCATTTTAGTAATGGGTCAAATGATTCACTTTTTATGATGCTTCCAAAGGTGCCTT
  GGCTTCTCTTCCCAACTGACAAATGCCAAAGTTGAGAAAAATGATCATAATTTTAGCATA
  AACAGAGCAGTCGGCGACACCGATTTTATAAATAAACTGAGCACCTTCTTTTTAAACAAA
  CAAATGCGGGTTTATTTCTCAGATGATGTTCATCCGTGAATGGTCCAGGGAAGGACCTTT
  CACCTTGTCTATATGGCATTATGTCATCACAAGCTCTGAGGCTTCTCCTTTCCATCCTGC
  GTGGACAGCTAAGACCTCAGTTTTCAATAGCATCTAGAGCAGTGGGACTCAGCTGGGGTG
  ATTTCGCCCCCCATCTCCGGGGGAATGTCTGAAGACAATTTTGGTTACCTCAATGAGGGA
  GTGGAGGAGGATACAGTGCTACTACCAACTAGTGGATAGAGGCCAGGGATGCTGCTCAAC
  CTCCTACCATGTACAGGACGTCTCCCCATTACAACTACCCAATCCGAAGTGTCAACTGTG
  TCAGGGCTAAGAAACCCTGGTTTTGAGTAGAAAAGGGCCTGGAAAGAGGGGAGCCAACAA
  ATCTGTCTGCTTCCTCACATTAGTCATTGGCAAATAAGCATTCTGTCTCTTTGGCTGCTG
  CCTCAGCACAGAGAGCCAGAACTCTATCGGGCACCAGGATAACATCTCTCAGTGAACAGA
  GTTGACAAGGCCTATGGGAAATGCCTGATGGGATTATCTTCAGCTTGTTGAGCTTCTAAG
  TTTCTTTCCCTTCATTCTACCCTGCAAGCCAAGTTCTGTAAGAGAAATGCCTGAGTTCTA
  GCTCAGGTTTTCTTACTCTGAATTTAGATCTCCAGACCCTGCCTGGCCACAATTCAAATT
  AAGGCAACAAACATATACCTTCCATGAAGCACACACAGACTTTTGAAAGCAAGGACAATG
  ACTGCTTGAATTGAGGCCTTGAGGAATGAAGCTTTGAAGGAAAAGAATACTTTGTTTCCA
  GCCCCCTTCCCACACTCTTCATGTGTTAACCACTGCCTTCCTGGACCTTGGAGCCACGGT
  GACTGTATTACATGTTGTTATAGAAAACTGATTTTAGAGTTCTGATCGTTCAAGAGAATG
  ATTAAATATACATTTCCTAAAAAAAAAAAAAAAAAACTCGAGC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_024626 unedited
  TTTTCGNAATATGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGGGCAGCGG
  CAGCTCCACTCAGCCAGTACCCAGATACGCTGGGAACCTTCCCCAGCCATGGCTTCCCTG
  GGGCAGATCCTCTTCTGGAGCATAATTAGCATCATCATTATTCTGGCTGGAGCAATTGCA
  CTCATCATTGGCTTTGGTATTTCAGGGAGACACTCCATCACAGTCACTACTGTCGCCTCA
  GCTGGGAACATTGGGGAGGATGGAATCCTGAGCTGCACTTTTGAACCTGACATCAAACTT
  TCTGATATCGTGATACAATGGCTGAAGGAAGGTGTTTTAGGCTTGGTCCATGAGTTCAAA
  GAAGGCAAAGATGAGCTGTCGGAGCAGGATGAAATGTTCAGAGGCCGGACAGCAGTGTTT
  GCTGATCAAGTGATAGTTGGCAATGCCTCTTTGCGGCTGAAAAACGTGCAACTCACAGAT
  GCTGGCACCTACAAATGTTATATCATCACTTCTAAAGGCAAGGGGAATGCTAACCTTGAG
  TATAAAACTGGAGCCTTCAGCATGCCGGAAGTGAATGTGGACTATAATGCCAGCTCAGAG
  ACCTTGCCGTGTGAGGCTCCCCGATGGTTCCCCCAGCCCACAGTGGTCTGGGCATCCCAA
  GTTGACCAGNGAGCCAACCTCTTCGGAGTCTCCATACCAGCTTTGAGCTGAACTCTGAGA
  ATGTGACCATGAAGGGTGTGTCTGTGCTCTTACATGTACGATCAACACACATACTCCCGT
  ATGATTGAAAATGACATTGCCCAAGCACAGGGGATATCAAAGTGACAGATCCGGAAATCA
  AAAGCCGGAGCCCCTACCGCTGCTAAACTCAAAGGCTTCCCTCGGGGGCTCCTTCTTTCT
  TTGACATCACTGGGCACT
  
  3' Read Nucleotide Sequence

  >OriGene 3' genomic read for NM_024626 unedited
  TATGGACCCGCGGCCGCAATCTAGAGCTCGAGTTTTTTTTTTTTTTTTTTAGGAAATGTA
  TATTTAATCATTCTCTTGAACGATCAGAACTCTAAAATCAGTTTTCTATAACAACATGTA
  ATACAGTCACCGTGGCTCCAAGGTCCAGGAAGGCAGTGGTTAACACATGAAGAGTGTGGG
  AAGGGGGCTGGAAACAAAGTATTCTTTTCCTTCAAAGCTTCATTCCTCAAGGCCTCAATT
  CAAGCAGTCATTGTCCTTGCTTTCAAAAGTCTGTGTGTGCTTCATGGAAGGTATATGTTT
  GTTGCCTTAATTTGAATTGTGGCCAGGCAGGGTCTGGAGATCTAAATTCAGAGTAAGAAA
  ACCTGAGCTAGAACTCAGGCATTTCTCTTACAGAACTTGGCTTGCAGGGTAGAATGAAGG
  GAAAGAAACTTAGAAGCTCAACAAGCTGAAGATAATCCCATCAGGCATTTCCCATAGGCC
  TTGTCAACTCTGTTCACTGAGAGATGTTATCCTGGTGCCCGATAGAGTTCTGGCTCTCTG
  TGCTGAGGCAGCAGCCAAAGAGACAGAATGCTTATTTGCCAATGACTAATGTGAGGAAGC
  AGACAGATTTGTTGGCTCCCCTCTNTTCAGGCCCTCTTCTACTCAAAACCAGGGTTTCTT
  AGCCCTGACACAGTTGACACTTCGGATTGNGTAGTTGTAATGGGGAGACGTCCTGTACAT
  GGTANGAGGTTGAGCAGCATCCCTGGCCTCTATTCACTAGTTGGTAGTAGCACTGTATCC
  TNCTCCACTCCTCATTGAGTAACCAAAATGTCTTCAGACATTCCCCGNAGAGGGGCCGAA
  ATCACCCACTGAGTCCACTGTCTANAGCTATGAAACTGAGTCTTACTGCCCCCAGATGAA
  AGAGAACCTANAGCTGTGAGACTAAGCCTTAGACAGTGAAGTCCTCCTGCCATCACGATA
  ACTATT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_024626
• ORF Size: 849 bp
• Insert Size: 2900
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_024626.1, NP_078902.1
• RefSeq Size: 1811
• RefSeq ORF: 849
• Locus ID: 79679
• Protein Families: Transmembrane
• Gene Summary: This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
  Transcript Variant: This variant (1) encodes the longest protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.