RNF128 (NM_024539) Human Untagged Clone

CAT#: SC112168

RNF128 (untagged)-Human ring finger protein 128 (RNF128), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RNF128
• Synonyms: GRAIL
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_024539 edited
  GAATTCGGCACGAGGGGCGCTTAACGCCTGTAACCCGCACACGAATTTCACGGTGCCCAC
  GGTTTGGGGAAGCACCGTGCAAGTCTCTTGGTTGGCCCTCATCCAACGCGGCGGGGGCTG
  CACCTTCGCAGACAAGATCCATCTGGCTTATGAGAGAGGGGCGTCTGGAGCCGTCATCTT
  TAACTTCCCCGGGACCCGCAATGAGGTCATCCCCATGTCTCACCCGGGTGCAGTAGACAT
  TGTTGCAATCATGATCGGCAATCTGAAAGGCACAAAAATTCTGCAATCTATTCAAAGAGG
  CATACAAGTGACAATGGTCATAGAAGTAGGGAAAAAAACATGGCCCTTGGGTGAATCACT
  ATTCAATTTTTTTCGTTTCTGTGTCCTTTTTTATTATTACGGCGGCAACTGTGGGCTATT
  TTATCTTTTATTCTGCTCGAAGGCTACGGAATGCAAGAGCTCAAAGCAGGAAGCAGAGGC
  AATTAAAGGCAGATGCTAAAAAAGCTATTGGAAGGCTTCAACTACGCACACTGAAACAAG
  GAGACAAGGAAATTGGCCCTGATGGAGATAGTTGTGCTGTGTGCATTGAATTGTATAAAC
  CAAATGATTTGGTACGCATCTTAACGTGCAACCATATTTTCCATAAGACATGTGTTGACC
  CATGGCTGTTAGAACACAGGACTTGCCCCATGTGCAAATGTGACATACTCAAAGCTTTGG
  GAATTGAGGTGGATGTTGAAGATGGATCAGTGTCTTTACAAGTCCCTGTATCCAATGAAA
  TATCTAATAGTGCCTCCTCCCATGAAGAGGATAATCGCAGCGAGACCGCATCATCTGGAT
  ATGCTTCAGTACAGGGAACAGATGAACCGCCTCTGGAGGAACACGTGCAGTCAACAAATG
  AAAGTCTACAGCTGGTAAACCATGAAGCAAATTCTGTGGCAGTGGATGTTATTCCTCATG
  TTGACAACCCAACCTTTGAAGAAGACGAAACTCCTAATCAAGAGACTGCTGTTCGAGAAA
  TTAAATCTTAAAATCTGTGTAAATAGAAAACTTGAACCATTAGTAATAACAGAACTGCCA
  ATCAGGGCCTAGTTTCTATTAATAAATTGGATAAATTTAATAAAATAAGAGTGATACTGA
  AAGTGCTCAGATGACTAATATTATGCTATAGTTAAATGGCTTAAAATATTTAACCTGTTA
  ACTTTTTTCCACAAACTCATTATAATATTTTTCATAGGCAAGTTTCCTCTCAGTAGTGAT
  AACAACATTTTTAGACATTCAAAACTGTCTTCAAGAAGTCACGTTTTTCATTTATAACAA
  TTTTCTTATAAAAACATGTTGCTTTTAAAATGTGGAGTAGCTGTAATCACTTTATTTTAT
  GATAGTATCTTAATGAAAAATACTACTTCTTTAGCTTGGGCTACATGTGTCAGGGTTTTT
  CTCCAGGTGCTTATATTGATCTGGAATTGTAATGTAAAAAGCAATGCAAACTTAGGCGAG
  TACTTCTTGAAATGTCTATTTAAGCTGCTTTAAGTTAATAGAAAAGATTAAAGCAAAATA
  TTCATTTTTACTTTTTCTTATTTTTAAAATTAGGCTGAATGTACTTCATGTGATTTGTCA
  ACCATAGTTTATCAGAGATTATGGACTTAATTGATTGGTATATTAGTGACATCAACTTGA
  CACAAGATTAGACAAAAAATTCCTTACAAAAATACTGTGTAACTATTTCTCAAACTTGTG
  GGATTTTTCAAAAGCTCAGTATATGAATCATCATACTGTTTGAAATTGCTAATGACAGAG
  TAAGTAACACTAATATTGGTCATTGATCTTCGTTCATGAATTAGTCTACAGAAAAAAAAT
  GTTCTGTAAAATTAGTCTGTTGAAAATGTTTTCCAAACAATGTTACTTTGAAAATTGAGT
  TTATGTTTGACCTAAATGGGCTAAAATTACATTAGATAAACTAAAATTCTGTCCGTGTAA
  CTATAAATTTTGTGAATGCATTTTCCTGGTGTTTGAAAAAGAAGGGGGGGAGAATTCCAG
  GTGCCTTAATATAAAGTTTGAAGCTTCATCCACCAAAGTTAAATAGAGCTATTTAAAAAT
  GCACTTTATTTGTACTCTGTGTGGCTTTTGTTTTAGAATTTTGTTCAAATTATAGCAGAA
  TTTAGGCAAAAATAAAACAGACATGTATTTTTGTTTGCTGAATGGATGAAACCATTGCAT
  TCTTGTACACTGATTTGAAATGCTGTAAATATGTCCCAATTTGTATTGATTCTCTTTAAA
  TATAAAATGTAAATAAAATATTCCAATAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_024539 unedited
  AATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGGCGCTTAACGCCTGTAAC
  CCGCACACGAATTTCACGGTGCCCACGGTTTGGGGAAGCACCGTGCAAGTCTCTTGGTTG
  GCCCTCATCCAACGCGGCGGGGGCTGCACCTTCGCAGACAAGATCCATCTGGCTTATGAG
  AGAGGGGCGTCTGGAGCCGTCATCTTTAACTTCCCCGGGACCCGCAATGAGGTCATCCCC
  ATGTCTCACCCGGGTGCAGTAGACATTGTTGCAATCATGATCGGCAATCTGAAAGGCACA
  AAAATTCTGCAATCTATTCAAAGAGGCATACAAGTGACAATGGTCATAGAAGTAGGGAAA
  AAAACATGGCCCTTGGGTGAATCACTATTCAATTTTTTTCGTTTCTGTGTCCTTTTTTAT
  TATTACGGCGGCAACTGTGGGCTATTTTATCTTTTATTCTGCTCGAAGGCTACGGAATGC
  AAGAGCTCAAAGCAGGAAGCAGAGGCAATTAAAGGCAGATGCTAAAAAAGCTATTGGAAG
  GCTTCAACTACGCACACTGAAACAAGGAGACAAGGAAATTGGCCCTGATGGAGATAGTTG
  TGCTGTGTGCATTGAATTGTATAAACCAAATGATTTGGTACGCATCTTAACGTGCAACCA
  TATTTTCCATAAGACATGTGTTGACCCATGGCTGTTAGACACAGGACTTGCCCCTGTGCA
  ATGTGACTACTCAAGCTTGGGATTGAGGTGATGTGAAATGGATCGTGGCTTACCAGTCCT
  GATCATGAAATCTAAATGCCTCTCCTGAGAGATATCGCGCAGACGCTCTCTGATATGCTC
  ATCAGGACAATGAACGCTTGAGGACCGTGCGCACAATGAAGCTACGTGGAACATGAGCAT
  TGGGCCGGGAGGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_024539 unedited
  GACGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTATTGGAATATTTTATTT
  ACATTTTATATTTAAAGAGAATCAATACAAATTGGGACATATTTACAGCATTTCAAATCA
  GTGTACAAGAATGCAATGGTTTCATCCATTCAGCAAACAAAAATACATGTCTGTTTTATT
  TTTGCCTAAATTCTGCTATAATTTGAACAAAATTCTAAAACAAAAGCCACACAGAGTACA
  AATAAAGTGCATTTTTAAATAGCTCTATTTAACTTTGGTGGATGAAGCTTCAAACTTTAT
  ATTAAGGCACCTGGAATTCTCCCCCCCTTCTTTTTCAAACACCAGGAAAATGCATTCACA
  AAATTTATAGTTACACGGACAGAATTTTAGTTTATCTAATGTAATTTTAGCCCATTTAGG
  TCAAACATAAACTCAATTTTCAAAGTAACATTGTTTGGAAAACATTTTCAACAGACTAAT
  TTTACAGAACATTTTTTTTCTGTAGACTAATTCATGAACGAAGATCAATGACCAATATTA
  GTGTTACTTACTCTGTCATTAGCAATTTCAAACAGTATGATGATTCATATACTGAGCTTT
  TGAAAAATCCCACAAGTTTGAGAAATAGTTACACAGTATTTTTGTAAGGAATTTTTTGTC
  TAATCTTGTGTCAAGTTGATGTCACTAATATACCAATCAATTAAGTCCATAATCTCTGAT
  AAACTATGGTTGACAAATCACATGAAGTACATTCAGCCTAATTTTAAAATAAGAAAAAGT
  AAAAATGAATATTTTGCTTTAATCTTTNCTATTAACTAAAGCAGCTTAATAGACATTTCA
  GAAGTACTCGCCTAGTTTGCATTGCTTTTTACATACATTNCAGACAATATAGCACCTGGA
  GAAAACCTGACCCATGTACCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_024539
• ORF Size: 1209 bp
• Insert Size: 2390
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_024539.3, NP_078815.3
• RefSeq Size: 2688
• RefSeq ORF: 1209
• Locus ID: 79589
• Domains: RING, PA
• Protein Families: Transmembrane
• Gene Summary: The protein encoded by this gene is a type I transmembrane protein that localizes to the endocytic pathway. This protein contains a RING zinc-finger motif and has been shown to possess E3 ubiquitin ligase activity. Expression of this gene in retrovirally transduced T cell hybridoma significantly inhibits activation-induced IL2 and IL4 cytokine production. Induced expression of this gene was observed in anergic CD4(+) T cells, which suggested a role in the induction of anergic phenotype. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) has an alternate 5' end exon compared to variant 1. The resulting isoform (2) has a distinct and shorter N-terminus, as compared to isoform 1.