HDAC7 (NM_015401) Human Untagged Clone

CAT#: SC112645

HDAC7 (untagged)-Human histone deacetylase 7 (HDAC7), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: HDAC7
• Synonyms: HD7; HD7A; HDAC7A
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_015401 edited
  GGGATGTGAGGCCGGCGCCCCAGCCCCCCGCCCCGCCATGAGCCCCCCGCTCTGAGGGCC
  CCGGCCCCTGGATGCACAGCCCCGGCGCTGATGGGACCCAGGTGAGCCCGGGTGCCCACT
  ACTGCAGCCCCACTGGCGCAGGCTGCCCCAGGCCCTGTGCAGACACACCAGGCCCTCAGC
  CGCAGCCCATGGACCTGCGGGTGGGCCAGCGGCCCCCAGTGGAGCCCCCACCAGAGCCCA
  CATTGCTGGCCCTGCAGCGTCCCCAGCGCCTGCACCACCACCTCTTCCTAGCAGGCCTGC
  AGCAGCAGCGCTCGGTGGAGCCCATGAGGCTCTCCATGGACACGCCGATGCCCGAGTTGC
  AGGTGGGACCCCAGGAACAAGAGCTGCGGCAGCTTCTCCACAAGGACAAGAGCAAGCGAA
  GTGCTGTAGCCAGCAGCGTGGTCAAGCAGAAGCTAGCGGAGGTGATTCTGAAAAAACAGC
  AGGCGGCCCTAGAAAGAACAGTCCATCCCAACAGCCCCGGCATTCCCTACAGAACCCTGG
  AGCCCCTGGAGACGGAAGGAGCCACCCGCTCCATGCTCAGCAGCTTTTTGCCTCCTGTTC
  CCAGCCTGCCCAGTGACCCCCCAGAGCACTTCCCTCTGCGCAAGACAGTCTCTGAGCCCA
  ACCTGAAGCTGCGCTATAAGCCCAAGAAGTCCCTGGAGCGGAGGAAGAATCCACTGCTCC
  GAAAGGAGAGTGCGCCCCCCAGCCTCCGGCGGCGGCCCGCAGAGACCCTCGGAGACTCCT
  CCCCAAGTAGTAGCAGCACGCCCGCATCAGGGTGCAGCTCCCCCAATGACAGCGAGCACG
  GCCCCAATCCCATCCTGGGCTCGGAGGCGCTCTTGGGCCAGCGGCTGCGGCTGCAGGAGA
  CTTCTGTGGCCCCGTTCGCCTTGCCGACAGTGTCCTTGCTGCCCGCAATCACTCTGGGGC
  TGCCCGCCCCTGCCAGGGCTGACAGTGACCGCAGGACCCATCCGACTCTGGGCCCTCGGG
  GGCCAATCCTGGGGAGCCCCCACACTCCCCTCTTCCTGCCCCATGGCTTGGAGCCCGAGG
  CTGGGGGCACCTTGCCCTCTCGCCTGCAGCCCATTCTCCTCCTGGACCCCTCAGGCTCTC
  ATGCCCCGCTGCTGACTGTGCCCGGGCTTGGGCCCTTGCCCTTCCACTTTGCCCAGTCCT
  TAATGACCACCGAGCGGCTCTCTGGGTCAGGCCTCCACTGGCCACTGAGCCGGACTCGCT
  CAGAGCCCCTGCCCCCCAGTGCCACCGCTCCCCCACCGCCGGGCCCCATGCAGCCCCGCC
  TGGAGCAGCTCAAAACTCACGTCCAGGTGATCAAGAGGTCAGCCAAGCCGAGTGAGAAGC
  CCCGGCTGCGGCAGATACCCTCGGCTGAAGACCTGGAGACAGATGGCGGGGGACCGGGCC
  AGGTGGTGGACGATGGCCTGGAGCACAGGGAGCTGGGCCATGGGCAGCCTGAGGCCAGAG
  GCCCCGCTCCTCTCCAGCAGCACCCTCAGGTGTTGCTCTGGGAACAGCAGCGACTGGCTG
  GGCGGCTCCCCCGGGGCAGCACCGGGGACACTGTGCTGCTTCCTCTGGCCCAGGGTGGGC
  ACCGGCCTCTGTCCCGGGCTCAGTCTTCCCCAGCCGCACCTGCCTCACTGTCAGCCCCAG
  AGCCTGCCAGCCAGGCCCGAGTCCTCTCCAGCTCAGAGACCCCTGCCAGGACCCTGCCCT
  TCACCACAGGGCTGATCTATGACTCGGTCATGCTGAAGCACCAGTGCTCCTGCGGTGACA
  ACAGCAGGCACCCGGAGCACGCCGGCCGCATCCAGAGCATCTGGTCCCGGCTGCAGGAGC
  GGGGGCTCCGGAGCCAGTGTGAGTGTCTCCGAGGCCGGAAGGCCTCCCTGGAAGAGCTGC
  AGTCGGTCCACTCTGAGCGGCACGTGCTCCTCTACGGCACCAACCCGCTCAGCCGCCTCA
  AACTGGACAACGGGAAGCTGGCAGGGCTCCTGGCACAGCGGATGTTTGTGATGCTGCCCT
  GTGGTGGGGTTGGGGTGGACACTGACACCATCTGGAATGAGCTTCATTCCTCCAATGCAG
  CCCGCTGGGCCGCTGGCAGTGTCACTGACCTCGCCTTCAAAGTGGCTTCTCGTGAGCTAA
  AGAATGGTTTCGCTGTGGTGCGGCCCCCAGGACACCATGCAGATCATTCAACAGCCATGG
  GCTTCTGCTTCTTCAACTCAGTGGCCATCGCCTGCCGGCAGCTGCAACAGCAGAGCAAGG
  CCAGCAAGATCCTCATTGTAGACTGGGACGTGCACCATGGCAACGGCACCCAGCAAACCT
  TCTACCAAGACCCCAGTGTGCTCTACATCTCCCTGCATCGCCATGACGACGGCAACTTCT
  TCCCGGGGAGTGGGGCTGTGGATGAGGTAGGGGCTGGCAGCGGTGAGGGCTTCAATGTCA
  ATGTGGCCTGGGCTGGAGGTCTGGACCCCCCCATGGGGGATCCTGAGTACCTGGCTGCTT
  TCAGGATAGTCGTGATGCCCATCGCCCGAGAGTTCTCTCCAGACCTAGTCCTGGTGTCTG
  CTGGATTTGATGCTGCTGAGGGTCACCCGGCCCCACTGGGTGGCTACCATGTTTCTGCCA
  AATGTTTTGGATACATGACGCAGCAACTGATGAACCTGGCAGGAGGCGCAGTGGTGCTGG
  CCTTGGAGGGTGGCCATGACCTCACAGCCATCTGTGACGCCTCTGAGGCCTGTGTGGCTG
  CTCTTCTGGGTAACAGGGTGGATCCCCTTTCAGAAGAAGGCTGGAAACAGAAACCCAACC
  TCAATGCCATCCGCTCTCTGGAGGCCGTGATCCGGGTGCACAGTAAATACTGGGGCTGCA
  TGCAGCGCCTGGCCTCCTGTCCAGACTCCTGGGTGCCTAGAGTGCCAGGGGCTGACAAAG
  AAGAAGTGGAGGCAGTGACCGCACTGGCGTCCCTCTCTGTGGGCATCCTGGCTGAAGATA
  GGCCCTCGGAGCAGCTGGTGGAGGAGGAAGAACCTATGAATCTCTAAGGCTCTGGAACCA
  TCTGCCCGCCCACCATGCCCTTGGGACCTGGTTCTCTTCTAACCCCTGGCAATAGCCCCC
  ATTCCTGGGTCTTTAGAGATCCTGTGGGCAAGTAGTTGGAACCAGAGAACAGCCTGCCTG
  CTTTGACAGTTATCCCAGGGAGCGTGAGAAAATCCCTGGGTCTAGAATGGGAACTGGAGA
  GGACCCTGAGAGGAGACGGGCTGGGCGGCGACCCCCACAGGGCTCTCGAGAACAGATTCT
  CCCCTCCAGTATGGGCCCTGGCTGTGGCCCCCATTCCTCAGGACTGCACAGAGGAGGACT
  GGCTCCGGCTCCGTCGGGCTCACCCTTAACCACTATTCCTGGCTCTGCAAACCCCAGACT
  TTGCACACAGCCTCAGGCTCCACACAGAAATGTGAACTTGGCCTCAGACAGGCTGGCCCT
  TCCTAGGCTCTAGGGGCTAGGGGGGAGTGGGGAGCCAAGAGGTCCCATATTCCTGAGTGC
  AGGGGTAGTCCCTCTCACCTGCTTCCTCAGACGACTCTGGAAGCTTCCCTCTACCACCGG
  GCACTGAGACGAAGCTCCCTGACAGCCGAGACTGGCAGCCCTCCATCTGGTCCGTACCCT
  CGCCAGAGGCCCCCCTACATCAACCTCCTGGCGATGCCCTGGTGGAGCAGATGGGTGCTC
  TGGGAGTCCTGTGCTTCCTGATCCAATGGTGCCAAACCCTTCATCTCCCCCAGAAGCGCA
  GCATACCCCTGGGACCCCTCGGCCACTGCCCACTCGGGGAGCCTTCTCTGTTTCTGGGGC
  CTCCCCCACCATAGCTCTGATTCCCACCCCACATAGGAATAGCCTGACTGAGGGGGAAGG
  GGTGGGAGAGAAGATACAGACATGGAGGAGGGGAGGCTGCTCTGGCAAAGTCTTCAAGGC
  TTTTGGGGGTCCAGGCCTGGGGTCAAGAAGGAAAATGTGTGTGAGCATGTGTGTGAGTGA
  GGCGTGTGTGTGAGCGTGTGTGTGAGTGAGGCGTGTGTGTGTGTCTTTCCTAGGACCCAC
  CATACCCTGTGTATGTATGCATGTTTTTGTAAAAAGGAAGAAAATGGAAAAAAATCTGAA
  CAATAAATGTTTTATTTGCTTCAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: Please inquire
• ACCN: NM_015401
• ORF Size: 2859 bp
• Insert Size: 4200
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: The ORF of this clone has been fully sequenced and found to be a perfect match to NM_015401.1.

Reference Data

• RefSeq: NM_015401.1, NP_056216.1
• RefSeq Size: 4206
• RefSeq ORF: 2859
• Locus ID: 51564
• Domains: Hist_deacetyl
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to mouse HDAC7 gene whose protein promotes repression mediated via the transcriptional corepressor SMRT. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1, also known as variant 3) encodes isoform a (also known as isoform c).