TRADD (NM_003789) Human Untagged Clone

CAT#: SC112703

TRADD (untagged)-Human TNFRSF1A-associated via death domain (TRADD)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TRADD
• Synonyms: Hs.89862
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC112703 sequence for NM_003789 edited (data generated by NextGen Sequencing)
  ATGGCAGCTGGGCAAAATGGGCACGAAGAGTGGGTGGGCAGCGCATACCTGTTTGTGGAG
  TCCTCGCTGGACAAGGTGGTCCTGTCGGATGCCTACGCGCACCCCCAGCAGAAGGTGGCA
  GTGTACAGGGCTCTGCAGGCTGCCTTGGCAGAGAGCGGCGGGAGCCCGGACGTGCTGCAG
  ATGCTGAAGATCCACCGCAGCGACCCGCAGCTGATCGTGCAGCTGCGATTCTGCGGGCGG
  CAGCCCTGTGGCCGCTTCCTCCGCGCCTACCGCGAGGGGGCGCTGCGCGCCGCGCTGCAG
  AGGAGCCTGGCGGCCGCGCTCGCCCAGCACTCGGTGCCGCTGCAACTGGAGCTGCGCGCC
  GGCGCCGAGCGGCTGGACGCTTTGCTGGCGGACGAGGAGCGCTGTTTGAGTTGCATCCTA
  GCCCAGCAGCCCGACCGGCTCCGGGATGAAGAACTGGCTGAGCTGGAGGATGCGCTGCGA
  AATCTGAAGTGCGGCTCGGGGGCCCGGGGTGGCGACGGGGAGGTCGCTTCGGCCCCCTTG
  CAGCCCCCGGTGCCCTCTCTGTCGGAGGTGAAGCCGCCGCCGCCGCCGCCACCTGCCCAG
  ACTTTTCTGTTCCAGGGTCAGCCTGTAGTGAATCGGCCGCTGAGCCTGAAGGACCAACAG
  ACGTTCGCGCGCTCTGTGGGTCTCAAATGGCGCAAGGTGGGGCGCTCACTGCAGCGAGGC
  TGCCGGGCGCTGCGGGACCCGGCGCTGGACTCGCTGGCCTACGAGTACGAGCGCGAGGGA
  CTGTACGAGCAGGCCTTCCAGCTGCTGCGGCGCTTCGTGCAGGCCGAGGGCCGCCGCGCC
  ACGCTGCAGCGCCTGGTGGAGGCACTCGAGGAGAACGAGCTCACCAGCCTGGCAGAGGAC
  TTGCTGGGCCTGACCGATCCCAATGGCGGCCTGGCCTAG
  
  Clone variation with respect to NM_003789.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003789 unedited
  GTTCAGATTTTNGTATACGACTTCACTATAGGCGGCNCGCGATTCGGCACGAGGGTAGAG
  CGGAGCCTGGCGGGCGTGGGAACCCAGGCCCCGCCGAGGCGGCCAGGAGGTGAGATGGCA
  GCTGGGCAAAATGGGCACGAAGAGTGGGTGGGCAGCGCATACCTGTTTGTGGAGTCCTCG
  CTGGACAAGGTGGTCCTGTCGGATGCCTACGCGCACCCCCAGCAGAAGGTGGCAGTGTAC
  AGGGCTCTGCAGGCTGCCTTGGCAGAGAGCGGCGGGAGCCCGGACGTGCTGCAGATGCTG
  AAGATCCACCGCAGCGACCCGCAGCTGATCGTGCAGCTGCGATTCTGCGGGCGGCAGCCC
  TGTGGCCGCTTCCTCCGCGCCTACCGCGAGGGGGCGCTGCGCGCCGCGCTGCAGAGGAGC
  CTGGCGGCCGCGCTCGCCCAGCACTCGGTGCCGCTGCAACTGGAGCTGCGCGCCGGCGCC
  GAGCGGCTGGACGCTTTGCTGGCGGACGAGGAGCGCTGTTTGAGTTGCATCCTAGCCCAG
  CAGCCCGACCGGCTCCGGGATGAAGAACTGGCTGAGCTGGAGGATGCGCTGCGAAATCTG
  AAGTGCGGCTCGGGGGCCCGGGGTGGCGACGGNGAGGTCGCTTCGGCCCCCTTGCAGCCC
  CCGGTGCCCTCTCTGTCGGAGGTGAAGCCGNCGNCGNCGNCGCCACCTGCCCAGACTTTT
  CTGTTCCAGGGTCAGCCTGTAGTGAATCGGCCGCTGAGCCTGAAGACCAACAGACGTTCG
  CGCGCTCTGTGGGTCTCAAATGGCGCAAGGTGGGGCGCTCACTGCANCGAGGCTGCNCGG
  CGCTGCGGAACCCNGCGCTGGACTCGCTGGCCTACGAGTCGAGCGCGAGGGACTGTACGA
  GCAAGCCTTCCAGCTGCTGCGNGCCTTGTGCAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003789 unedited
  TACCGCGGCACGCTTTTTAGNATCGAGTTTTTTTTTTTTTTTTTTATCCGTGTTATACTT
  TATTATCATTGCTTAACATTCGGGGTCCCACGCTGAGTGTGAGCTGGGGGCAGGCAAGAT
  TGATCCCTGTTTTACTTCACTGCAGCATCTGCAGCACCCAGGATGAAGTCCAGGACACCA
  AAGATCAAGGTGCTTCATGAGTGAAACTGTAAGGGCTGGCTGTAAGCCCCGCTTTTGGGA
  TGGGAGAAGGTGAGGCTGATCTACAAAGCAGGTCCCCCCCACCCCACACTCTATTAAAGT
  ACCTGAGGCAGAATCCCCAATGATGCACCCCCAGTGGTCTGGCTCCTGGGGAAGGCAATT
  AACTCTGTCCCAGTAGGCTCAGCAGATAGGCCAAGCGCAGTTCCAGGGCTCCGTGGCATG
  GACAGGGGTTCACCCATAACCGTATAAGGAACCCTAAGGCCATCCAGGCTCTCCAAAACC
  TGGCTGAACCCCTGGTCTAGGCCAGGTCGCCATTGGGATCGGCCAGGCCCAACAAGTTCT
  CTGACCGGCTGGTGAGCTCGCTCCACTTTAGCGCCATCACCAGGCCCTTGCATTGCGGCG
  CGGCGGCCCTCGACCTTGTTCCAACCCCGCATCTATCCGCAATGCCTGCCTTACACAGAC
  CCTTCTCCTTGCACCTCCCGGCCCCTTTATCCCCATCCCCGGGTTCCCGCATTATTCCGC
  CAGCCCTCCCTGACATGAGCCGCCCCCTCTCGTGTCATTCTTACCTCCCAAACACCCGCG
  AACGCCTGTTTGCACCTTCAGCCTTCTGGATCCATTTATCACCCGTTCGTCCCTGTAACA
  CCATATTTCGCCCGCCGCCCGCGCNGCCGTTGCTCTCACTCCCACCTACAGTTCTCGGCG
  TTTTTGTGGCCTCCAACCACTTATCTTTCTCCCTGGCTCCACTATTCCTTTCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003789
• ORF Size: 939 bp
• Insert Size: 1590
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003789.2, NP_003780.1
• RefSeq Size: 1482
• RefSeq ORF: 939
• Locus ID: 8717
• Domains: DEATH
• Protein Families: Druggable Genome
• Protein Pathways: Adipocytokine signaling pathway, Apoptosis, RIG-I-like receptor signaling pathway
• Gene Summary: The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (1) encodes a longer isoform (1).