MAP2K1IP1 (LAMTOR3) (NM_021970) Human Untagged Clone

CAT#: SC112835

LAMTOR3 (untagged)-Human late endosomal/lysosomal adaptor, MAPK and MTOR activator 3 (LAMTOR3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: LAMTOR3
• Synonyms: MAP2K1IP1; MAPBP; MAPKSP1; MP1; PRO0633; Ragulator3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_021970 edited
  GAATTCGGCACGAGGGTGACGGTGGCTTGAGGAGGAACCTGTCTTTAAAGCTGTCCCTGA
  AGTGACAGCGGAGAGAACCAGGCAGCCCAGAAACCCCAGGCGTGGAGATTGATCCTGCGA
  GAGAAGGGGGTTCATCATGGCGGATGACCTAAAGCGATTCTTGTATAAAAAGTTACCAAG
  TGTTGAAGGGCTCCATGCCATTGTTGTGTCAGATAGAGATGGAGTACCTGTTATTAAAGT
  GGCAAATGACAATGCTCCAGAGCATGCTTTGCGACCTGGTTTCTTATCCACTTTTGCCCT
  TGCAACAGACCAAGGAAGCAAACTTGGACTTTCCAAAAATAAAAGTATCATCTGTTACTA
  TAACACCTACCAGGTGGTTCAATTTAATCGTTTACCTTTGGTGGTGAGTTTCATAGCCAG
  CAGCAGTGCCAATACAGGACTAATTGTCAGCCTAGAAAAGGAACTTGCTCCATTGTTTGA
  AGAACTGAGACAAGTTGTGGAAGTTTCTTAATCTGACAGTGGTTTCAGTGTGTACCTTAT
  CTTCATTATAACAACACAATATCAATCCAGCAATCTTTAGACTACAATAATACTTTTATC
  CATGTGCTCAAGAAAGGGCCCCTTTTTCCAACTTATACTAAAGAGCTAGCATATAGATGT
  AATTTATAGATAGATCAGTTGCTATATTTTCTGGTGTAGGGTCTTTCTTATTTAGTGAGA
  TCTAGGGATACCACAGAAATGGTTCAGTCTATCACAGCTCCCATGGAGTTAGTCTGGTCA
  CCAGATATGGATGAGAGATTCTATTCAGTGGATCAGAATCAAACTGGTACATTGATCCAC
  TTGAGCCGTTAAGTGCTGCCAATTGTACAATATGCCCAGGCTTGCAGAATAAAGCCAACT
  TTTTATTGTGAATAATAATAAGGACATATTTTTCTTCAGATTATGTTTTATTTCTTTGCA
  TTGAGTGAGGAACATAAAATGGCTTGGTAAAAGTAATAAAATCAGTACAATCACTAACTT
  TCCTTTGTACATATTATTTTGCAGTATAGATGAATATTACTAATCAGTTTGATTATTCTC
  AGAGGGTGCTGCTCTTTAATGAAAATGAAAATTATAGCTAATGTTTTTTCCTCAAACTCT
  GCTTTCTGTAACCAATCAGTGTTTTAATGTTTGTGTGTTCTTCATAAAATTTAAATACAA
  TTCGTTATTCTGTTTCCAATGTTAGTATGTATGTAAACATGATAGTACAGCCATTTTTTT
  CATATGTGAGTAAAAATAAAATAGTATTTTTAAAAATATAAXXXXXXXXXXXXXXXXXXX
  XXACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_021970 unedited
  CCGGTTCAGGCATATTTGTNAATACGCATTTCACTATAGGGNNCGGCCGCGCAATTCGGC
  ACGAGGGTGACGGTGGCTTGAGGAGGAACCTGTCTTTAAACCTGTCCCTGAAGTGACAGC
  GGAGAGAACCAGGCAGCCCAGAAACCCCAGGCGTGGAGATTGATCCTGCGAGAGAAGGGG
  GTTCATCATGGCGGATGACCTAAAGCGATTCTTGTATAAAAAGTTACCAAGTGTTGAAGG
  GCTCCATGCCATTGTTGTGTCAGATAGAGATGGAGTACCTGTTATTAAAGTGGCAAATGA
  CAATGCTCCAGAGCATGCTTTGCGACCTGGTTTCTTATCCACTTTTGCCCTTGCAACAGA
  CCAAGGAAGCAAACTTGGACTTTCCAAAAATAAAAGTATCATCTGTTACTATAACACCTA
  CCAGGTGGTTCAATTTAATCGTTTACCTTTGGTGGTGAGTTTCATAGCCAGCAGCAGTGC
  CAATACAGGACTAATTGTCAGCCTAGAAAAGGAACTTGCTCCATTGTTTGAAGAACTGAG
  ACAAGTTGTGGAAGTTTCTTAATCTGACAGTGGTTTCAGTGTGTACCTTATCTTCATTAT
  AACAACACAATATCAATCCAGCAATCTTTAGACTACAATAATACTTTTATCCATGTGCTC
  AAGAAAGGGCCCCTTTTTCCAACTTATACTAAAGAGCTAGCATATAGATGTAATTTATAG
  ATAGATCAGTTGCTATATTTTCTGGTGTACGGTCTTTCTTATTTAGTGAGATCCTAGGAT
  ACACAGAAATGTTTCAGTCTATCACAGCTCCCATGGAGTTAGTCTGGCCACCAGATATGG
  ATGAGAGATTCTATTCAGTGCATCAGAATCAACCTGGTCATTGATCCACCTGAGCCGCTA
  AGTGCTGCCAATTGTACATT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_021970 unedited
  TTAAAATACTATTTTATTTTTACTCACATATGNAAAAAATGGCTGTACTATCATGTTTAC
  ATACATACTAACATTGGAAACAGAATAACGAATTGTATTTAAATTTTATGAAGAACACAC
  AAACATTAAAACACTGATTGGTTACAGAAAGCAGAGTTTGAGGAAAAAACATTAGCTATA
  ATTTTCATTTTCATTAAAGAGCAGCACCCTCTGAGAATAATCAAACTGATTAGTAATATT
  CATCTATACTGCAAAATAATATGTACAAAGGAAAGTTAGTGATTGTACTGATTTTATTAC
  TTTTACCAAGCCATTTTATGTTCCTCACTCAATGCAAAGAAATAAAACATAATCTGAAGA
  AAAATATGTCCTTATTATTATTCACAATAAAAAGTTGGCTTTATTCTGCAAGCCTGGGCA
  TATTGTACAATTGGCAGCACTTAACGGCTCAAGTGGATCAATGTACCAGTTTGATTCTGA
  TCCACTGAATAGAATCTCTCATCCATATCTGGTGACCAGACTAACTCCATGGGAGCTGTG
  ATAGACTGAACCATTTCTGTGGTATCCCTAGATCTCACTAAATAAGAAAGACCCTACACC
  AGAAAATATAGCAACTGATCTATCTATAAATTACATCTATATGCTAGCTCTTTAGTATAA
  GTTGGAAAAAGGGGCCCTTTCTTGAGCACATGGATAAAAGTATTATTGTAGTCTAAAGAT
  TGCTGGATTGATATTGTGTTGTTATAATGAAGATAAGGTACACACTGAAACCACTGTCAG
  ATTAGAAACTTCCACAACTTGTCTCAGTTCTTAAACAATGGAGNNCAGTNCTTTTCTAGG
  CTGACAATTAGTCCTGTATTGGCACTGCTGCTGGCATGAAACTCACCACCAAAGGTAACG
  ATTAAATGAACCACTGNTAGGTGTATAGTACAGATGATCTTTATTTTTGGAAGTCAGTTT
  GCTTCTTGTCTGTGCAAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_021970
• ORF Size: 375 bp
• Insert Size: 1430
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_021970.2, NP_068805.1
• RefSeq Size: 1416
• RefSeq ORF: 375
• Locus ID: 8649
• Protein Families: Druggable Genome
• Protein Pathways: MAPK signaling pathway
• Gene Summary: This gene encodes a scaffold protein that functions in the extracellular signal-regulated kinase (ERK) cascade. The protein is localized to late endosomes by the mitogen-activated protein-binding protein-interacting protein, and binds specifically to MAP kinase kinase MAP2K1/MEK1, MAP kinase MAPK3/ERK1, and MAP kinase MAPK1/ERK2. Studies of the orthologous gene in mouse indicate that it regulates late endosomal traffic and cell proliferation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome 13. [provided by RefSeq, Aug 2011]
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1).