KTEL1 (KTELC1) (NM_020231) Human Untagged Clone

CAT#: SC113148

KTELC1 (untagged)-Human KTEL (Lys-Tyr-Glu-Leu) containing 1 (KTELC1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KTELC1
• Synonyms: CLP46, MDSRP, C3orf9, MDS010, hCLP46, KDELCL1, MGC32995
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC113148 sequence for NM_020231 edited (data generated by NextGen Sequencing)
  ATGGAGTGGTGGGCTAGCTCGCCGCTTCGGCTCTGGCTGCTGTTGTTCCTCCTGCCCTCA
  GCGCAGGGCCGCCAGAAGGAGTCAGGTTCAAAATGGAAAGTATTTATTGACCAAATTAAC
  AGGTCTTTGGAGAATTACGAACCATGTTCAAGTCAAAACTGCAGCTGCTACCATGGTGTC
  ATAGAAGAGGATCTAACTCCTTTCCGAGGAGGCATCTCCAGGAAGATGATGGCAGAGGTA
  GTCAGACGGAAGCTAGGGACCCACTATCAGATCACTAAGAACAGACTGTACCGGGAAAAT
  GACTGCATGTTCCCCTCAAGGTGTAGCGGTGTTGAGCACTTTATTTTGGAAGTGATCGGG
  CGTCTCCCTGACATGGAGATGGTGATCAATGTACGAGATTATCCTCAGGTTCCTAAATGG
  ATGGAGCCTGCCATCCCAGTCTTCTCCTTCAGTAAGACATCAGAGTACCATGATATCATG
  TATCCTGCTTGGACATTTTGGGAAGGGGGACCTGCTGTTTGGCCAATTTATCCTACAGGT
  CTTGGACGGTGGGACCTCTTCAGAGAAGATCTGGTAAGGTCAGCAGCACAGTGGCCATGG
  AAAAAGAAAAACTCTACAGCATATTTCCGAGGATCAAGGACAAGTCCAGAACGAGATCCT
  CTCATTCTTCTGTCTCGGAAAAACCCAAAACTTGTTGATGCAGAATACACCAAAAACCAG
  GCCTGGAAATCTATGAAAGATACCTTAGGAAAGCCAGCTGCTAAGGATGTCCATCTTGTG
  GATCACTGCAAATACAAGTATCTGTTTAATTTTCGAGGCGTAGCTGCAAGTTTCCGGTTT
  AAACACCTCTTCCTGTGTGGCTCACTTGTTTTCCATGTTGGTGATGAGTGGCTAGAATTC
  TTCTATCCACAGCTGAAGCCATGGGTTCACTATATCCCAGTCAAAACAGATCTCTCCAAT
  GTCCAAGAGCTGTTACAATTTGTAAAAGCAAATGATGATGTAGCTCAAGAGATTGCTGAA
  AGGGGAAGCCAGTTTATTAGGAACCATTTGCAGATGGATGACATCACCTGTTACTGGGAG
  AACCTCTTGAGTGAATACTCTAAATTCCTGTCTTATAATGTAACGAGAAGGAAAGGTTAT
  GATCAAATTATTCCCAAAATGTTGAAAACTGAACTATAG
  
  Clone variation with respect to NM_020231.3
  224 g=>a;685 a=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_020231 unedited
  TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTGCAGTAGGTCTGCC
  GGCGATGGAGTGGTGGGCTAGCTCGCCGCTTCGGCTCTGGCTGCTGTTGTTCCTCCTGCC
  CTCAGCGCAGGGCCGCCAGAAGGAGTCAGGTTCAAAATGGAAAGTATTTATTGACCAAAT
  TAACAGGTCTTTGGAGAATTACGAACCATGTTCAAGTCAAAACTGCAGCTGCTACCATGG
  TGTCATAGAAGAGGATCTAACTCCTTTCCGAGGAGGCATCTCCAGGAAGATGATGGCAGA
  GGTAGTCAGACGGAAGCTAGGGACCCACTATCAGATCACTAAGAACAGACTGTACCGGGA
  AAATGACTGCATGTTCCCCTCAAGGTGTAGCGGTGTTGAGCACTTTATTTTGGAAGTGAT
  CGGGCGTCTCCCTGACATGGAGATGGTGATCAATGTACGAGATTATCCTCAGGTTCCTAA
  ATGGATGGAGCCTGCCATCCCAGTCTTCTCCTTCAGTAAGACATCAGAGTACCATGATAT
  CATGTATCCTGCTTGGACATTTTGNGAAGGGGGACCTGCTGTTTGGCCAATTTATCCTAC
  AGGTCTTGGACGGTGGGACCTCTTCAGAGAAGATCTGGTAAGGTCACCAGCACAGTGGCC
  ATGGAAAAAAAAAAACTCTACAGCATATTTCCGAGGATCAAGGACAAGTCCCGAACGAGA
  TCCTCTCATTCTTCTGTCTCGGAAAACCCANAACTTGNTGATGCAGATTACACCAAAACC
  CAGCCTGGGAATCTATGAAAGATCCCTTTAGAAGCCAGCTGCTAAGGATGTCCATCCTGG
  GGGACACTGCACATACAATATCTGTTTAATTTCCCAAGCGTACCTGCAAGTTN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_020231 unedited
  TGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGGCTTTAGAGAGCAT
  TAAGAAGTAGGGCATGAAGGCACAAAAAGGGAACCTGAAATCCAATTGCAATAATTACTC
  ATGCAATTGGCCTCTTTCTATGTGGCATTATAGAAACCTCCTGAGTAACACAGTTTATGG
  TTTTACAAAAGAGAACTCCTACATCATTGCATGGCATGGCTACCGCTTCCTTAGACCATT
  CAGAGAATGATCCCCAAGTATTTTTCATAAACCCCATAGGGTTTCCTACATTAAAATAAA
  GTGACAGAGATCACGCCTTGAATAATTTCACAATTCCAGCAATGAGTTGTACTACTTCCA
  AATGACGAATTTTCTGCTCCAAATAATGGGACAAAGGGCATCATCACATGGACACAGTCA
  ATTTCACAGTGATGGACTCACACAGGTGGATGATCTGAGGCACAAGCTGTGATTGGTCTT
  AAGAAAATGAAAGGTAGAGTTGGGTTCAAAATCCACATCTCACGATTTCTGGTCCTTATT
  CATCCAAAAAGTTGAACTGCTTCATATCAGTGTATTAGACACATTTTAAATCTTTCTCAA
  GAGTTGCTCTGGGTGCAGCATGATAAGGAAAACCAGGTATTTGGCTTGATAGCAGATATT
  CAAGGTATAGGTGCCAAGCTTATGGTAAGCTTCTCACCGTAGGATATCTGAGATCTGTTG
  CCACAAAGAGGACTATGGTCCTACGATGACTACTATAGTTCAGTTTTCACATTTTTGGGA
  TAATTTGATCATACCTTTCCTTCTCNGTACATTATAGACAGGAATTAGAGTATCACTCAC
  GAGTTCTCCCAGTACAGGTGATGTCATTCATCTGCAAATGTTCCCTATAACTGGCTTNCC
  TTTNCAGCATCTCTGACTACATATCATTG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_020231
• ORF Size: 1179 bp
• Insert Size: 1780
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_020231.3, NP_064616.2
• RefSeq Size: 1973
• RefSeq ORF: 1179
• Locus ID: 56983
• Domains: CAP10
• Gene Summary: This gene encodes a protein with both O-glucosyltransferase and O-xylosyltransferase activity which localizes to the lumen of the endoplasmic reticulum. This protein has a carboxy-terminal KTEL motif which is predicted to function as an endoplasmic reticulum retention signal. This gene is an essential regulator of Notch signalling and likely plays a role in cell fate and tissue formation during development. It may also play a role in the pathogenesis of leukemia. Mutations in this gene have been associated with the autosomal dominant genodermatosis Dowling-Degos disease 4. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]