Neuroligin 3 (NLGN3) (NM_018977) Human Untagged Clone

CAT#: SC113280

NLGN3 (untagged)-Human neuroligin 3 (NLGN3), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NLGN3
• Synonyms: HNL3
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC113280 sequence for NM_018977 edited (data generated by NextGen Sequencing)
  ATGTGGCTGCGGCTTGGCCCGCCCTCGCTGTCCCTGAGCCCCAAGCCCACGGTTGGCAGG
  AGCCTGTGCCTCACCCTGTGGTTCCTCAGTTTGGCGCTGAGGGCCAGTACCCAGGCCCCA
  GCACCCACAGTCAACACTCACTTTGGGAAGCTAAGGGGTGCCCGAGTACCACTGCCCAGT
  GAGATCCTGGGGCCTGTGGACCAATACCTGGGGGTGCCCTACGCAGCTCCCCCGATCGGC
  GAGAAACGTTTCCTGCCCCCTGAACCACCCCCATCCTGGTCGGGCATCCGGAACGCCACA
  CACTTTCCCCCAGTGTGCCCCCAGAACATCCACACAGCTGTGCCCGAAGTCATGCTGCCG
  GTCTGGTTCACTGCCAACTTGGATATCGTCGCTACTTACATCCAGGAGCCCAACGAAGAC
  TGTCTCTACCTGAACGTCTATGTGCCGACGGAGGATGGATCCGGCGCTAAGAAACAGGGC
  GAGGACTTAGCGGATAATGACGGGGATGAAGATGAAGACATCCGGGACAGTGGTGCTAAA
  CCCGTCATGGTCTACATCCACGGAGGCTCTTACATGGAAGGGACAGGCAACATGATTGAT
  GGCAGCATCCTCGCCAGTTATGGCAATGTCATCGTCATCACCCTCAACTATCGGGTTGGA
  GTGCTAGGTTTCCTGAGTACTGGAGATCAGGCTGCCAAGGGCAACTATGGGCTCCTTGAC
  CAGATCCAGGCCCTCCGCTGGGTGAGCGAGAATATTGCCTTCTTCGGGGGAGACCCCCGC
  CGGATCACTGTCTTTGGCTCGGGCATTGGTGCATCCTGCGTCAGCCTCCTCACGTTGTCA
  CATCACTCAGAGGGACTTTTCCAGAGAGCCATCATCCAAAGTGGCTCTGCTCTGTCCAGC
  TGGGCTGTGAACTACCAACCAGTGAAGTACACCAGCCTGCTGGCAGACAAAGTGGGCTGT
  AATGTGCTGGACACCGTGGATATGGTGGACTGTCTTCGGCAAAAGAGTGCCAAGGAGCTG
  GTAGAGCAGGACATCCAGCCAGCCCGCTACCACGTGGCCTTTGGCCCTGTGATTGATGGT
  GATGTCATTCCTGATGACCCTGAGATCCTCATGGAGCAGGGCGAGTTCCTCAACTATGAC
  ATCATGCTAGGTGTCAACCAGGGCGAGGGTCTCAAGTTTGTGGAAGGGGTGGTGGACCCT
  GAGGATGGTGTCTCTGGCACTGACTTTGACTATTCCGTCTCCAATTTTGTGGACAATCTG
  TATGGCTATCCTGAGGGTAAGGACACCCTGCGAGAGACCATCAAGTTCATGTATACAGAC
  TGGGCAGACCGTGACAACCCTGAGACCCGCCGTAAAACACTGGTGGCACTCTTCACTGAC
  CACCAGTGGGTGGAGCCCTCAGTGGTGACAGCCGATCTGCATGCCCGCTACGGCTCGCCT
  ACCTACTTCTACGCCTTCTATCATCACTGCCAGAGCCTCATGAAGCCTGCTTGGTCAGAT
  GCAGCTCATGGGGATGAAGTACCCTATGTTTTTGGGGTTCCTATGGTAGGCCCCACTGAC
  CTTTTCCCCTGCAACTTCTCCAAGAATGATGTTATGCTCAGTGCTGTCGTCATGACCTAT
  TGGACCAACTTTGCCAAGACTGGGGATCCCAACAAGCCGGTCCCCCAGGACACCAAGTTC
  ATTCACACCAAGGCCAACCGCTTTGAGGAAGTGGCCTGGTCCAAATACAATCCCCGAGAC
  CAGCTCTACCTTCACATCGGGCTGAAACCAAGGGTCCGAGATCATTACCGGGCCACTAAG
  GTGGCCTTTTGGAAACATCTGGTGCCCCACCTATACAACCTGCATGACATGTTCCACTAT
  ACGTCCACCACCACCAAAGTGCCGCCTCCGGATACCACCCACAGCTCCCACATCACCCGC
  AGGCCCAATGGCAAGACCTGGAGCACCAAGCGGCCAGCCATCTCACCTGCCTACAGCAAC
  GAGAATGCCCAGGGGTCCTGGAACGGGGACCAGGATGCAGGGCCACTCCTGGTGGAGAAC
  CCTCGTGACTACTCCACTGAATTAAGTGTCACCATCGCCGTGGGGGCCTCCCTCCTGTTC
  CTTAACGTTCTGGCCTTCGCTGCCCTCTACTACCGTAAGGACAAACGGCGCCAGGAGCCC
  CTGCGGCAGCCTAGCCCTCAGCGGGGAGCCGGGGCCCCGGAGTTGGGAGCTGCTCCAGAG
  GAGGAGCTGGCAGCATTACAACTGGGCCCCACCCACCACGAGTGTGAGGCCGGTCCCCCC
  CATGACACGCTGCGCCTCACTGCATTGCCCGACTACACCCTGACCCTGCGGCGCTCCCCG
  GATGACATCCCACTCATGACCCCCAACACCATCACTATGATCCCCAACTCCCTGGTAGGG
  CTGCAGACATTGCACCCCTATAACACCTTTGCCGCAGGGTTCAACAGTACCGGGCTGCCC
  CACTCACACTCCACTACCCGGGTATAG
  
  Clone variation with respect to NM_018977.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_018977 unedited
  CCACGCCCTTCGCACGAGGCCAGGCTGCCTGAGAGCTGATCTCGGGGATTCGGGTGCGGA
  GCCCTTGGCCTGGAGGCGATATGGGTGGTCCGTGGCCCGGTTCAGTCGCTTGCAGCAGCC
  CGGGGAACAGGCCTGTCTGGCCCTGAGGGAGTCCCCTTTCTGAAGCTGTGGTGCTTGNAC
  TCCNGCTCTCTACATTGCTGGGCACCTGTAGGTGTCCCTCGAGAGCTCAGTTTTGAGGTT
  CAAGTCAGTGTGGCCATGAAGGGGCTGCCTATTGGGCTGATGCTGTGACCCTGGAGTCTG
  CCTCTCCTGCCAGTCCCCCTGCCCGGAACATGTGGCTGCGGCTTGGCCCGCCCTCGCTGT
  CCCTGAGCCCCAAGCCCACGGTTGGCAGGAGCCTGTGCCTCACCCTGTGGTTCCTCAGTT
  TGGCGCTGAGGGCCAGTACCCAGGCCCCAGCACCCACAGTCAACACTCACTTTGGGAAGC
  TAAGGGGTGCCCGAGTACCACTGCCCAGTGAGATCCTGGGGCCTGTGGACCAATACCTGG
  GGGTGCCCTACGCAGCTCCCCCGATCGGCGAGAAACGTTTCCTGCCCCCTGAACCACCCC
  CATCCTGGTCGGGCATCCGGAACGCCCCACACTTTTCCCCAGTGTGCCCCCCGAACATCC
  CCACAGCTGTGCCCGAAGTCATGCTGCCGGTCCTGGTTCACTGCCAACTTGGATATCGTC
  GCTACTTACTTCCAGGAGCCCACCGAAGACTGTCTCTACCTGAACGTCTATGTCCGAACG
  AAGATGGATCCCGCGCCTAAAAACAGGGCCAGGAACTTACCGGATAATGACCGGGGATGA
  AAATAAAAACCTCCCGGACCATGGTGCTTAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_018977 unedited
  TTTGGTCCGAGGCCGCTTCTAAGATCGGTTTTTTTTTTTTTTTTTTTTGGGAGAGCTAAC
  TGGATTTTTTATTTTTATATCAAGACACTGTGTTTAAAATTTTTACAAAGGACAAACTCC
  ATGGGTTTCCGTTAGTGTTTTAAGAACTTTTCTTTAAAAAAAAAAAAAAACCAACAACAA
  CAAAAAACACCGCCTTTTTGAAAGAGAAATGACAGACACAAAAGACTGTAAAGAAAATGG
  GGCGAATTTCTGATAGCATTTCCCCAAGGGCAGAGGCAAAACCCAGATCAGACCTGGGGG
  CCCAATAGTGATGTGGCTTCCATAGTACGTTGTTCACCAAATCTAAGGTCACCTGGTCTG
  GCCAGGCCAATGCTGTTGGCCTTTGGGGAAGCAGGTCACCCTGCAGGCTCTGCAGCCCTC
  CACACGGACACAGAGAGAGTTGGAGATCTCTCCCCTACGACCCTCCAGCTCCATCCAGTG
  CTAGCCCCTTTCTCCTTCCACCCCATGGGCTTGCTTAAATCTGTTTCCTTCCTGGGGGTC
  TTGTTCCTTGGTCTGATTGTGTGAGCACTGGGGGTCCTAGAGCCAGAGAGACCTTCGGGC
  CTGAAGCCCTCCCTTCCAGAGGCTCTTATCACTCATGGGTTGGAAAAGCATTTGTTCCCA
  AATTTAAAAAGAAAAATTCACAAAACAAGACCCATAAAAAAGACCAAGTCCTGGGGAGGG
  AAGACCATCCCGCTCTTTAAGCCTCCAATCCTGGATTTGTCGGCGGGGCACTTCCAAAGA
  GGCCAAGGCGAACCCAAGGGGGTGCCAACTGTTGCTTTCAGCCCCCCAGGATGGCCGCGG
  GCACATTAGAGAGCTTGCTCAGCTCGCTGTTATAGGTCCCTCGGTTACCGAGGACTTACT
  GGGTGCCATTTAAAGGTTTGGGCAAGCCTACTCCCGTTATTGGGTTCTGGACAAGCGGGG
  GATGCCACACTCTCTCTTTGTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_018977
• ORF Size: 2487 bp
• Insert Size: 3800
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_018977.2, NP_061850.2
• RefSeq Size: 3905
• RefSeq ORF: 2487
• Locus ID: 54413
• Domains: COesterase
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs)
• Gene Summary: This gene encodes a member of a family of neuronal cell surface proteins. Members of this family may act as splice site-specific ligands for beta-neurexins and may be involved in the formation and remodeling of central nervous system synapses. Mutations in this gene may be associated with autism and Asperger syndrome. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Oct 2009]
  Transcript Variant: This variant (2) lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1. Isoform 2 has also been referred to as HNL3L, or the long form.