UBC3B (UBE2R2) (NM_017811) Human Untagged Clone

CAT#: SC113961

UBE2R2 (untagged)-Human ubiquitin-conjugating enzyme E2R 2 (UBE2R2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBE2R2
• Synonyms: CDC34B; E2-CDC34B; UBC3B
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC113961 sequence for NM_017811 edited (data generated by NextGen Sequencing)
  ATGGCCCAGCAGCAGATGACCAGCTCGCAGAAGGCCCTGATGCTCGAGCTGAAATCCCTG
  CAGGAGGAACCGGTGGAGGGCTTCCGGATCACCCTGGTGGACGAGTCCGACCTCTACAAC
  TGGGAGGTGGCCATCTTCGGACCCCCCAACACCCTCTACGAAGGCGGCTACTTCAAGGCG
  CATATTAAATTTCCTATTGACTACCCCTATTCACCACCTACCTTCAGATTCTTGACCAAA
  ATGTGGCACCCCAACATTTATGAGAATGGAGATGTATGCATTTCGATTCTTCATCCGCCT
  GTAGATGACCCACAGAGTGGAGAACTGCCTTCTGAAAGGTGGAATCCTACTCAGAATGTG
  AGGACTATCCTATTAAGTGTAATCTCACTGCTTAATGAGCCCAACACCTTCTCCCCAGCC
  AATGTCGATGCTTCAGTTATGTTCAGGAAATGGAGAGACAGTAAAGGAAAAGACAAAGAA
  TATGCTGAAATTATTAGGAAACAAGTTTCAGCCACTAAGGCCGAAGCAGAAAAGGATGGA
  GTGAAGGTCCCCACAACCCTGGCGGAATACTGCATCAAAACTAAAGTGCCTTCCAATGAC
  AACAGCTCAGATTTGCTTTACGACGACTTGTATGATGACGACATTGATGATGAAGATGAG
  GAGGAGGAAGATGCCGACTGTTATGATGATGATGATTCTGGGAATGAGGAGTCGTGA
  
  Clone variation with respect to NM_017811.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_017811 unedited
  GATTTTGTAAACACGACTTCACTATAGNNGGCGGCCGCGCAATTCGGCACGAGGCCCGGC
  CGGTGCGTGAGGACTGGGGCCCGGGCCCGGCGCCGCCGCCGCCGCCGCCGCCGCGATGGC
  CCAGCAGCAGATGACCAGCTCGCAGAAGGCCCTGATGCTCGAGCTGAAATCCCTGCAGGA
  GGAACCGGTGGAGGGCTTCCGGATCACCCTGGTGTTTCTAGTCCGACCTCTACAACTGGG
  AGGTGGCCATCTTCGGACCCCCCAACACCCTCTACGAAGGCGGCTACTTCAAGGCGCATA
  TTAAATTTCCTATTGACTACCCCTATTCACCACCTACCTTCAGATTCTTGACCAAAATGT
  GGCACCCCAACATTTATGAGAATGGAGATGTATGCATTTCGATTCTTCATCCGCCTGTAG
  ATGACCCACAGAGTGGAGAACTGCCTTCTGAAAGGTGGAATCCTACTCAGAATGTGAGGA
  CTATCCTATTAAGTGTAATCTCACTGCTTAATGAGCCCAACACCTTCTCCCCAGCCAATG
  TCGATGCTTCAGTTATGTTCAGGAAATGGAGAGACAGTAAAGGAAAAGACAAAGAATATG
  CTGAAATTATTAGGAAACAAGTTTCAGCCACTAAGGCCGAAGCAGANAAGGATGGAGTGA
  AGGTCCCCACAACCCTGGCGGAATACTGCATCAAAACTAAAGTGCCTTCCAATGACAACA
  GCTCAGATTTGCTTTACGACGACTTGTATGATGACGACATTGATGATGAAGATGAGGAGG
  AGGAAGATGCCGACTGTTATGATGATGATGATTCTGGGAATGANGAGTCGTGACGTGCTC
  CTTCAGTGCCCCTGTACTGCCCTGCCATCTCAAGCCCAAAGGAGGGGAGCAAGTGGNGAC
  CTGGCCATGGCCCTTCAGCAAACCTATCACAGCGGTGGGGGAACACACCAGCTCCTGCTG
  ACTCCTTTATGGACTCAGTTGGCTCTTTTTAGGCN
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_017811 unedited
  TATCGAGAGCCGCAATCTANAGTCGAGTTTTTTTCTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTCTATGGAAAGTATGAATATTTATTTCAGGCTTTCGATCCCAATCGATTTCAAAAA
  ACAAAGTCTGATTTCTCTCCTCAAAGCAGCTGAGGCCTCCATGTTACGATGGTTTCATGG
  AGATTGAAGGAGCACATTTCATCAGGCTTAGCACAAAGTCCCTGATGCCCACCATGTCCC
  AGCCTTAGGAAAGGAAAGAAACAGAATTCACCACCATGGGGCTGAACGAATGCACACACA
  CTAATGTAAATGAGCAGCTAAACCTTGGCAAATTTGTTTTTTTTTTTTTTTAAAGTTTGT
  TTTGGGGGTTTTTTTCCATTTTCTTTTGCTACCCAGTATATGCAGCACTTGTGAACTCCC
  AACAGGTTCCCAGCTTTAAACACATTAAACATCTTGAAAGACTATTGAATTCTTCAAAAA
  TCTAAAAACAGACCAAACGTGTTTTGCTGTGAACATTCTGTAAAAACAAAGTGAGGCGGG
  AGTTTGGGTTCATGTTTTTTAAAAAAAGAATCAATATAGTGATGGAAGGGTAAAGAATGC
  AAAAATTCAAACATTCTGTGGAGGGTTACTCTCTCTCCATTAAAGGCCCATAAAAAGGAG
  CAAACTGAGATCCATAAGGGGAGTCAGCAGGAGCTGTGTGTGTTTCCCCACCCGCTGTGA
  ATAGGTTTTTGCTGAGGGGCCATGGCCAGTTCCCCACTTGCTCCCCTCCCTTTTGCCTGA
  GATGCAGGCCATCACGGGGCACTGAAAGAGCACGTTACGACTCCTCATTCCCAGATTATT
  ATTATCATAACAGTCGGTATCTTCCTCCTCCTCATTTCATCATCATGGGNAATCAACAAG
  NCGCCGAAAACAAATCTGACTGTTGTCATTGGAAGGCACTTATTTTGAGGCACTATCCCG
  CAGGGTGTGGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_017811
• ORF Size: 717 bp
• Insert Size: 1530
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_017811.3, NP_060281.2
• RefSeq Size: 4457
• RefSeq ORF: 717
• Locus ID: 54926
• Domains: UBCc
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: Protein kinase CK2 is a ubiquitous and pleiotropic Ser/Thr protein kinase involved in cell growth and transformation. This gene encodes a protein similar to the E2 ubiquitin conjugating enzyme UBC3/CDC34. Studies suggest that CK2-dependent phosphorylation of this ubiquitin-conjugating enzyme functions by regulating beta-TrCP substrate recognition and induces its interaction with beta-TrCP, enhancing beta-catenin degradation. [provided by RefSeq, Jul 2008]