Dexras1 (RASD1) (NM_016084) Human Untagged Clone

CAT#: SC114441

RASD1 (untagged)-Human RAS, dexamethasone-induced 1 (RASD1), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RASD1
• Synonyms: AGS1; DEXRAS1; MGC:26290
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC114441 sequence for NM_016084 edited (data generated by NextGen Sequencing)
  ATGAAACTGGCCGCGATGATCAAGAAGATGTGCCCGAGCGACTCGGAGCTGAGTATCCCG
  GCCAAGAACTGCTATCGCATGGTCATCCTCGGCTCGTCCAAGGTGGGCAAGACGGCCATC
  GTGTCGCGCTTCCTCACCGGCCGCTTCGAGGACGCCTACACGCCTACCATCGAGGACTTC
  CACCGCAAGTTCTACTCCATCCGCGGCGAGGTCTACCAGCTCGACATCCTCGACACGTCC
  GGCAACCACCCGTTCCCCGCCATGCGGCGCCTCTCCATCCTCACAGGAGACGTTTTCATC
  CTGGTGTTCAGTCTGGACAACCGCGACTCCTTCGAGGAGGTGCAGCGGCTCAGGCAGCAG
  ATCCTCGACACCAAGTCTTGCCTCAAGAACAAAACCAAGGAGAACGTGGACGTGCCCCTG
  GTCATCTGCGGCAACAAGGGTGACCGCGACTTCTACCGCGAGGTGGACCAGCGCGAGATC
  GAGCAGCTGGTGGGCGACGACCCCCAGCGCTGCGCCTACTTCGAGATCTCGGCCAAGAAG
  AACAGCAGCCTGGACCAGATGTTCCGCGCGCTCTTCGCCATGGCCAAGCTGCCCAGCGAG
  ATGAGCCCAGACCTGCACCGCAAGGTCTCGGTGCAGTACTGCGACGTGCTGCACAAGAAG
  GCGCTGCGGAACAAGAAGCTGCTGCGGGCCGGCAGCGGCGGCGGCGGCGGCGACCCGGGC
  GACGCCTTTGGCATCGTGGCACCCTTCGCGCGCCGGCCCAGCGTACACAGCGACCTCATG
  TACATCCGCGAGAAGGCCAGCGCCGGCAGCCAGGCCAAGGACAAGGAGCGCTGCGTCATC
  AGCTAG
  
  Clone variation with respect to NM_016084.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_016084 unedited
  TGTCAGCATTTGTATACGACTCACTATAGGCGGCCGCGAATCGGCACGAGGCCCAGATCC
  TGGGAGAACCCCAGCCGAGCCCAGCCTAGCCCGAGCCCAGCCCGAGCGGAGCCGGAGCCC
  CAAGCCCGAGCCGCGCCCAGCCCGAGCAGAGCCCTCCAGCCGCTCACCCCGCGTGCCACC
  CCAGCGACCCTCAGCCGCTCTCTGCCCTTCTCTCGGCCCCGCGCCCGCCCTCGCGGCCCC
  TCTGCCCAATGAAACTGGCCGCGATGATCAAGAAGATGTGCCCGAGCGACTCGGAGCTGA
  GTATCCCGGCCAAGAACTGCTATCGCATGGTCATCCTCGGCTCGTCCAAGGTGGGCAAGA
  CGGCCATCGTGTCGCGCTTCCTCACCGGCCGCTTCGAGGACGCCTACACGCCTACCATCG
  AGGACTTCCACCGCAAGTTCTACTCCATCCGCGGCGAGGTCTACCAGCTCGACATCCTCG
  ACACGTCCGGCAACCACCCGTTCCCCGCCATGCGGCGCCTCTCCATCCTCACAGGAGACG
  TTTTCATCCTGGTGTTCAGTCTGGACAACCGCGACTCCTTCGAGGAGGTGCAGCGGCTCA
  GGCAGCAGATCCTCGACACCAAGTCTTGCCTCAAGAACAAAACCAAGGAGAACGTGGGAC
  GTGCCCCTGGTCATCTGCGGCAACAAGGGTGACCGCGACTTCTACCGCGAGGTGGACCAG
  CGCGAGATCGAGCAGCTGTTGGGCGACGACCCCCAGCGCTGCGCCTACTTCGAGATCTCG
  GCCAAGAAGAACAGCAGCCTGGACCAGATGTTCCGCGCGCTCTNCGCCATGGNCAAGCTG
  CCCAGCGAGATGAGCCCAGACCTGCACCGCAAGGTCTCCGGGCAGTACTGCCGACGTGCT
  GCACAAGAAGGCGCTGCGGTACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_016084 unedited
  NNNCCTACTCTGNNACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTCAT
  TTTAAATTATTTTATTGTATATTAAAAAACCAAATAAAGCAATAACTTTAAAGACCTCAG
  ACACACACAGTATAAACACCTGGGTAAGGTTTTGTTCGTGTCCATGTTGACACCGGAACT
  ACCGTTAAAGTGCAAGTTTTGTTTTGTGTTCCTTTGTGCAGTTTCACTCACATGTAAACA
  AGTCACTTGGCTATGATTTGACCCACGCCCCCCCGCTTAGTTTCGGGAGGGCAGAGGCTC
  TACCGGCTGTCACAGCAACCCGGAATCACAGACAAGATAATGCCCCGTGGGTCCTGACCC
  TCAAGCGGGCATGACGGTTTCTTGAAGCCTAGCAGAGGCTGGATAACTTCACATCCCTCC
  CCCACCCCGCGCTCACTCTTAGGTCTTTGAGAAGATAAATCCACCCTCGGCTGGGCCCTC
  GCTCCCAAAGTTATGGGGGTGGCGGGCCTCAATGGGGGACCGGGGGTGGGGAATAGTCCC
  AGTCTTGGCCCGTTCTCTTTCCTTCCGGAGCAGATGACCGTCCCTTCTCGGTTCAGTGGC
  GCCTCCCCAGTGCTGGGGGCGGATCGCCGGGAGGGGAGACCCCAGTCCGCGCGCGCTCCC
  CGCCTGTGGCGCACCGGCCCCGTGGATTTGACTTAACAAAAAGTCCTCCTTTAGTTGTGT
  TCCCAGCGCCGCGGGGTTCCTAACTGATGACCCACCGCTTCTTGTCCTTGGCCTGGCTGC
  AGGCGCTTGCCTTCTCGCGACTGCCCTGAAGCCCTTTTGAACCCTGGCCCGGTCCGCGAA
  GGTTGCACAATCCCAAGGCGTCCCCCGTTTCCCCGCCTCTTCCTCCTTTATGCCCCTAAC
  AACTTTTTGTTCCGACACGCCN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_016084
• ORF Size: 846 bp
• Insert Size: 4000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_016084.3, NP_057168.1
• RefSeq Size: 1758
• RefSeq ORF: 846
• Locus ID: 51655
• Domains: ras, RAN, RAS, RHO, RAB
• Protein Families: Druggable Genome
• Gene Summary: This gene encodes a member of the Ras superfamily of small GTPases and is induced by dexamethasone. The encoded protein is an activator of G-protein signaling and acts as a direct nucleotide exchange factor for Gi-Go proteins. This protein interacts with the neuronal nitric oxide adaptor protein CAPON, and a nuclear adaptor protein FE65, which interacts with the Alzheimer's disease amyloid precursor protein. This gene may play a role in dexamethasone-induced alterations in cell morphology, growth and cell-extracellular matrix interactions. Epigenetic inactivation of this gene is closely correlated with resistance to dexamethasone in multiple myeloma cells. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
  Transcript Variant: This variant (1) is the longer transcript and encodes the longer isoform (1).