Claudin 15 (CLDN15) (NM_014343) Human Untagged Clone

CAT#: SC115054

CLDN15 (untagged)-Human claudin 15 (CLDN15), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CLDN15
• Synonyms: FLJ42715; MGC19536
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_014343 edited
  CTCCAGGGTAAGTCTGCCCCCCCCACCCTCGTGGGGCGGGGAGCCCGGGGCAGCCCAGAG
  GCTGGGGGGAGGGGGTGGACTTTTGGCCCGTTTCGGTTATTCCCTCCATCTCGTCAACAG
  CTGCCGCGCGCAGGCTTAGCTCATTCCTCTGACCTGCCAGGAAGCAGAGAGACCCACAGA
  GCAGGAGGGAGGCAGAAAGTGGAGACGGACCTGAGCCCGAGGAAGAGGCAGGCAGAGGCT
  GAGGCTGATTCCACCCCAGCCTGCCTGGACAACCCTCCTTAGCCGCAGCCCCTTCCAGTT
  CCCTAGGGGTTCTGCCCCTCCCCCTCTCTGGGGCACCAGCCCCCCAGGGTCCTGCATCCC
  ACCATGTCGATGGCTGTGGAAACCTTTGGCTTCTTCATGGCAACTGTGGGGCTGCTGATG
  CTGGGGGTGACTCTGCCAAACAGCTACTGGCGAGTGTCCACTGTGCACGGGAACGTCATC
  ACCACCAACACCATCTTCGAGAACCTCTGGTTTAGCTGTGCCACCGACTCCCTGGGCGTC
  TACAACTGCTGGGAGTTCCCGTCCATGCTGGCCCTCTCTGGGTATATTCAGGCCTGCCGG
  GCACTCATGATCACCGCCATCCTCCTGGGCTTCCTCGGCCTCTTGCTAGGCATAGCGGGC
  CTGCGCTGCACCAACATTGGGGGCCTGGAGCTCTCCAGGAAAGCCAAGCTGGCGGCCACC
  GCAGGGGCCCTCCACATTCTGGCCGGTATCTGCGGGATGGTGGCCATCTCCTGGTACGCC
  TTCAACATCACCCGGGACTTCTTCGACCCCTTGTACCCCGGAACCAAGTACGAGCTGGGC
  CCCGCCCTCTACCTGGGGTGGAGCGCCTCACTGATCTCCATCCTGGGTGGCCTCTGCCTC
  TGCTCCGCCTGCTGCTGCGGCTCTGACGAGGACCCAGCCGCCAGCGCCCGGCGGCCCTAC
  CAGGCTCCAGTGTCCGTGATGCCCGTCGCCACCTCGGACCAAGAAGGCGACAGCAGCTTT
  GGCAAATACGGCAGAAACGCCTACGTGTAGCAGCTCTGGCCCGTGGGCCCCGCTGTCTTC
  CCACTGCCCCAAGGAGAGGGGACCTGGCCGGGGCCCATTCCCCTATAGTAACCTCAGGGG
  CCGGCCACGCCCCGCTCCCGTAGCCCCGCCCCGGCCACGGCCCCGTGTCTTGCACTCTCA
  TGGCCCCTCCAGGCCAAGAACTGCTCTTGGGAAGTCGCATATCTCCCCTCTGAGGCTGGA
  TCCCTCATCTTCTGACCCTGGGTTCTGGGCTGTGAAGGGGACGGTGTCCCCGCACGTTTG
  TATTGTGTATAAATACATTCATTAATAAATGCATATTGTGACCGTTAAAAAAAAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_014343
• ORF Size: 687 bp
• Insert Size: 1400
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: NM_014343.1, NP_055158.1
• RefSeq Size: 1258
• RefSeq ORF: 687
• Locus ID: 24146
• Domains: PMP22_Claudin
• Protein Families: Transmembrane
• Protein Pathways: Cell adhesion molecules (CAMs), Leukocyte transendothelial migration, Tight junction
• Gene Summary: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. Alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jun 2010]
  Transcript Variant: This variant (2) has a shorter and alternate 5' UTR, as compared to variant 1.