DNA Polymerase lambda (POLL) (NM_013274) Human Untagged Clone

CAT#: SC115324

POLL (untagged)-Human polymerase (DNA directed), lambda (POLL), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: POLL
• Synonyms: BETAN; POLKAPPA
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115324 sequence for NM_013274 edited (data generated by NextGen Sequencing)
  ATGGATCCCAGGGGTATCTTGAAGGCATTTCCCAAGCGGCAGAAAATTCATGCTGATGCA
  TCATCAAAAGTACTTGCAAAGATTCCTAGGAGGGAAGAGGGAGAAGAAGCAGAAGAGTGG
  CTGAGCTCCCTTCGGGCCCATGTTGTGCGCACTGGCATTGGACGAGCCCGGGCAGAACTC
  TTTGAGAAGCAGATTGTTCAGCATGGCGGCCAGCTATGCCCTGCCCAGGGCCCAGGTGTC
  ACTCACATTGTGGTGGATGAAGGCATGGACTATGAGCGAGCCCTCCGCCTTCTCAGACTA
  CCCCAGCTGCCCCCGGGTGCTCAGCTGGTGAAGTCAGCCTGGCTGAGCTTGTGCCTTCAG
  GAGAGGAGGCTGGTGGATGTAGCTGGATTCAGCATCTTCATCCCCAGTAGGTACTTGGAC
  CATCCACAGCCCAGCAAGGCAGAGCAGGATGCTTCTATTCCTCCTGGCACCCATGAGGCC
  CTGCTTCAGACAGCCCTTTCTCCTCCTCCTCCTCCCACCAGGCCTGTGTCTCCTCCCCAA
  AAGGCAAAAGAGGCACCAAACACCCAAGCCCAGCCCATCTCTGATGATGAAGCCAGTGAT
  GGGGAAGAAACCCAGGTTAGTGCAGCTGATCTGGAAGCCCTCATCAGTGGCCACTACCCC
  CCCTCCCTTGAGGGAGATTGTGAGCCTAGCCCAGCCCCTGCTGTCCTGGATAAGTGGGTC
  TGTGCACAGCCCTCAAGCCAGAAGGCGACCAATCACAACCTCCATATCACAGAGAAGCTG
  GAAGTTCTGGCCAAAGCCTACAGTGTTCAGGGAGACAAGTGGAGGGCCCTGGGCTATGCC
  AAGGCCATCAATGCCCTCAAGAGCTTCCATAAGCCTGTCACCTCGTACCAGGAGGCCTGC
  AGTATCCCTGGGATTGGGAAGCGGATGGCTGAGAAAATCATAGAGATCCTGGAGAGCGGG
  CATTTGCGGAAGCTGGACCATATCAGTGAGAGCGTGCCTGTCTTGGAGCTCTTCTCCAAC
  ATCTGGGGAGCTGGGACCAAGACTGCCCAGATGTGGTACCAACAGGGCTTCCGAAGTCTG
  GAAGACATCCGCAGCCAGGCCTCCCTGACAACCCAGCAGGCCATCGGCCTGAAGCATTAC
  AGTGACTTCCTGGAACGTATGCCCAGGGAGGAGGCTACAGAGATTGAGCAGACAGTCCAG
  AAAGCAGCCCAGGCCTTTAACTCCGGGCTGCTGTGTGTGGCATGTGGTTCATACCGACGG
  GGAAAGGCGACCTGTGGTGATGTCGACGTGCTCATCACTCACCCAGATGGCYGGTCCCAC
  CGGGGTATCTTCAGCCGCCTCCTTGACAGTCTTCGGCAGGAAGGGTTCCTCACAGATGAC
  TTGGTGAGCCAAGAGGAGAATGGTCAGCAACAGAAGTACTTGGGGGTGTGCCGGCTCCCA
  GGGCCAGGGCGGCGGCACCGGCGCCTGGACATCATCGTGGTGCCCTATAGCGAGTTTGCC
  TGTGCCCTGCTCTACTTCACCGGCTCTGCACACTTCAACCGCTCCATGCGAGCCCTGGCC
  AAAACCAAGGGCATGAGTCTGTCAGAACATGCCCTCAGCACTGCTGTGGTCCGGAACACC
  CATGGCTGCAAGGTGGGGCCTGGCCGAGTGCTGCCCACTCCCACTGAGAAGGATGTCTTC
  AGGCTCTTAGGCCTCCCCTACCGAGAACCTGCTGAGCGGGACTGGTGA
  
  Clone variation with respect to NM_013274.3
  661 a=>c;1224 t=>c;1312 c=>y
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_013274 unedited
  NCTTGCAGAATTTTGTAATACGACTCACTTATAGGGCGGCCGCGAATTCGCACGAGGCAA
  TTCTGGATTTCCACGTGCAGCAGCCCTGACCACGCTCCAATAGGCCGGGATCCAGCCATA
  CTTCAATGGATCCCAGGGGTATCTTGAAGGCATTTCCCAAGCGGCAGAAAATTCATGCTG
  ATGCATCATCAAAAGTACTTGCAAAGATTCCTAGGAGGGAAGAGGGAGAAGAAGCAGAAG
  AGTGGCTGAGCTCCCTTCGGGCCCATGTTGTGCGCACTGGCATTGGACGAGCCCGGGCAG
  AACTCTTTGAGAAGCAGATTGTTCAGCATGGCGGCCAGCTATGCCCTGCCCAGGGCCCAG
  GTGTCACTCACATTGTGGTGGATGAAGGCATGGACTATGAGCGAGCCCTCCGCCTTCTCA
  GACTACCCCAGCTGCCCCCGGGTGCTCAGCTGGTGAAGTCAGCCTGGCTGAGCTTGTGCC
  TTCAGGAGAGGAGGCTGGTGGATGTAGCTGGATTCAGCATCTTCATCCCCAGTAGGTACT
  TGGACCATCCACAGCCCAGCAAGGCAGAGCAGGATGCTTCTATTCCTCCTGGCACCCATG
  AGGCCCTGCTTCAGACAGCCCTTTCTCCTCCTCCTCCTCCCACCAGGCCTGTGTCTCCTC
  CCCAAAAGGCAAAAGAGGCACCAAACACCCAAGCCCAGCCCATCTCTGATGATGAAGCCA
  GTGATGGGGAAGAAACCCAGGTTAGTGCAGCTGATCTGGAAGCCCTCATCAGTGGCCACT
  ACCCCCCCTCCCTTGAGGGNAGATTGTGAGCCTAGCCCAGCCCCTGCTGTCCTGGATAAG
  TGGGGTCTGTGCACAGCCCTCAAGCCAGAAGCGACCAATCACAACCTNCATATCACAGAG
  AAGCTGGNAAGTTCTGGGCCAAGCCTACAGTGNTCAGGNAGACCAAGTGGNAGGCCCNNT
  GGCTTC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_013274 unedited
  NTTCTACTTGNACCCGGCCGCAATCTANGATCGAGTTTTTTTTTTTTTTTTTTCAGGTTC
  AATGTCAAATGCACTTTACTGGGCCCCTGGGCCTCCCAACACTGTCCTCACCAAGGCTGG
  GGCACCCCATTCCCAGCACCACCAGCTGACCGGGAAGCAGGACGGATAGAGGGAACACAT
  GTGGAATGGCTGTTCTCCTACCCCAAAGGTGCCGGATGATGTTGACAGCACGGCTGCTTC
  CCTCTCCCCTGCAGCTTCTGTCCCCACCCAGCAGCTTGGCCTTTCCCATAGCAGGGAAGG
  GGGATACCTGGGGCTTCAAACCAGCCACCTGCTCCTGCTTAAAATGGGGCAAGGGGCCAT
  TTGCAAAATTCTTCGAGGGGCAGTGGTGAGGTAAAAGGGGTGGCAGCCTGCTCCTGTCTG
  GGAGAGGGCTGGGCAGACACTGGGAGCCGGGCAGACACTGGGAGCCGGGCTGGCTCTTGC
  TTCAGGCCCAGAGCCCTGGGCCCTGCTCGCTGAGGAAGCTGGTGGTTGGAGCGGCGAGGT
  TCAACCAGCTGAGGCTGGAAGGAGTACTGGGTGGCCAGGAGGGGTAGCCAGTCCAACTCG
  GCTCTCCTCAGCACCCCCAGCCATGGGTCACCAGTCCCGCTCAGCAGGTTCTCGGTAGGG
  GAGGCCTAAGAGCCTGAAGACATCCTTCTCAGTGGGAGTGGGCAGCACTCGGCCAGGCCC
  CACCTTGCAGCCATGGGGTGTTCCGGACCACAGCAGTGCTGAGGGCATGTTCTGACAGAC
  TCATGCCCTTTGGTTNTGGCCCAGGCTCGCATGGAGCGGNTGAAGTGTGCAAAGCCGGTG
  AAGTAAAGCAGGGCACAGGCAAACTCGCTATAGGGCACCACGATGATGTCCAGGCGCCGG
  TGCCGNCGCCTGGCCCTGGGAGCCNGCACACCCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_013274
• ORF Size: 1728 bp
• Insert Size: 3460
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_013274.2, NP_037406.1
• RefSeq Size: 2702
• RefSeq ORF: 1728
• Locus ID: 27343
• Domains: POLXc
• Protein Families: Druggable Genome
• Protein Pathways: Base excision repair, Non-homologous end-joining
• Gene Summary: This gene encodes a DNA polymerase. DNA polymerases catalyze DNA-template-directed extension of the 3'-end of a DNA strand. This particular polymerase, which is a member of the X family of DNA polymerases, likely plays a role in non-homologous end joining and other DNA repair processes. Alternatively spliced transcript variants have been described. [provided by RefSeq, Mar 2010]
  Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same isoform (a).