FBXW2 (NM_012164) Human Untagged Clone

CAT#: SC115470

FBXW2 (untagged)-Human F-box and WD repeat domain containing 2 (FBXW2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: FBXW2
• Synonyms: FBW2; Fwd2; Md6
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115470 sequence for NM_012164 edited (data generated by NextGen Sequencing)
  ATGGAGAGAAAGGACTTTGAGACATGGCTTGATAACATTTCTGTTACATTTCTTTCTCTG
  ACGGACTTGCAGAAAAATGAAACTCTGGATCACCTGATTAGTCTGAGTGGGGCAGTCCAG
  CTCAGGCATCTCTCCAATAACCTAGAGACTCTCCTCAAGCGGGACTTCCTCAAACTCCTT
  CCCCTGGAGCTCAGTTTTTATTTGTTAAAATGGCTCGATCCTCAGACTTTACTCACATGC
  TGCCTCGTCTCTAAACAGTGGAATAAGGTGATAAGTGCCTGTACAGAGGTGTGGCAGACT
  GCATGTAAAAATTTGGGCTGGCAGATAGATGATTCTGTTCAGGACGCTTTGCACTGGAAG
  AAGGTTTATTTGAAGGCTATTTTGAGAATGAAGCAACTGGAGGACCATGAAGCCTTTGAA
  ACCTCGTCATTAATTGGACACAGTGCCAGAGTGTATGCACTTTACTACAAAGATGGACTT
  CTCTGTACAGGGTCAGATGACTTGTCTGCAAAGCTGTGGGATGTGAGCACAGGGCAGTGC
  GTTTATGGCATCCAGACCCACACTTGTGCAGCGGTGAAGTTTGATGAACAGAAGCTTGTG
  ACAGGCTCCTTTGACAACACTGTGGCTTGCTGGGAATGGAGTTCCGGAGCCAGGACCCAG
  CACTTTCGGGGGCACACGGGGGCGGTATTTAGCGTGGACTACAATGATGAACTGGATATC
  TTGGTGAGCGGCTCTGCAGACTTCACTGTGAAAGTATGGGCTTTATCTGCTGGGACATGC
  CTGAACACACTCACCGGGCACACGGAATGGGTCACCAAGGTAGTTTTGCAGAAGTGCAAA
  GTCAAGTCTCTCTTGCACAGTCCTGGAGACTACATCCTCTTAAGTGCAGACAAATATGAG
  ATTAAGATTTGGCCAATTGGGAGAGAAATCAACTGTAAGTGCTTAAAGACATTGTCTGTC
  TCTGAGGATAGAAGTATCTGCCTGCAGCCAAGACTTCATTTTGATGGCAAATACATTGTC
  TGTAGTTCAGCACTTGGTCTCTACCAGTGGGACTTTGCCAGTTATGATATTCTCAGGGTC
  ATCAAGACTCCTGAGATAGCAAACTTGGCCTTGCTTGGCTTTGGAGATATCTTTGCCCTG
  CTGTTTGACAACCGCTACCTGTACATCATGGACTTGCGGACAGAGAGCCTGATTAGTCGC
  TGGCCTCTGCCAGAGTACAGGAAATCAAAGAGAGGCTCAAGCTTCCTGGCAGGCGAAGCA
  TCCTGGCTGAATGGACTGGATGGGCACAATGACACGGGCTTGGTCTTTGCCACCAGCATG
  CCTGACCACAGTATTCACCTGGTGTTGTGGAAGGAGCACGGCTGA
  
  Clone variation with respect to NM_012164.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012164 unedited
  TTCAAATTTTGTAATACGACTTCACTATAGGGCGGCCGCGAATTCGCACGAGGGACGCAG
  GCAGCNACCGGAGCCGCTCCCCTGTGAGGCTGCGGACCGGGAGCAGCGGCCGCAGGCGCC
  ATGGCTGCGGAGCGGACCCGGCCGCTGCAAGGCTCTGGCGGTCCGAGCGTGCCTAGTAGC
  TGTGAACCCGGCGCGAGGTCCCGGGCCCCGGGGCGCTCGCTCAGGTAAATTTTTCCATAA
  CCTTATGGAGAGAAAGGACTTTGAGACATGGCTTGATAACATTTCTGTTACATTTCTTTC
  TCTGACGGACTTGCAGAAAAATGAAACTCTGGATCACCTGATTAGTCTGAGTGGGGCAGT
  CCAGCTCAGGCATCTCTCCAATAACCTAGAGACTCTCCTCAAGCGGGACTTCCTCAAACT
  CCTTCCCCTGGAGCTCAGTTTTTATTTGTTAAAATGGCTCGATCCTCAGACTTTACTCAC
  ATGCTGCCTCGTCTCTAAACAGTGGAATAAGGTGATAAGTGCCTGTACAGAGGTGTGGCA
  GACTGCATGTAAAAATTTGGGCTGGCAGATAGATGATTCTGTTCAGGACGCTTTGCACTG
  GAAGAAGGTTTATTTGAAGGCTATTTTGAGAATGAAGCAACTGGAGGACCATGAAGCCTT
  TGAAACCTCGTCATTAATTGGACACAGTGCCAGAGTGTATGCACTNTACTACAAAGATGG
  ACTTCTCTGTACAGGGTCAGATGACTTGTCTGCANAGCTGTGGGATGTGAGCACAGGGCA
  GTGCGTTTATGGCATCCAGACCCACACTTGTGCAGCGGTGAAAGTTTGATGAACAGAAGC
  TTGTGACAGGCTCCTTTGACACACTGTGGCTTGCTGGNAATGGAGTCCGGAGCCAGGACC
  CACACTTTCGGGGCACACGGGGCCGTATTTAGCGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_012164 unedited
  NNNNTTTTACTCTGGACCCGCGGCCGCATNCTANGANCGAGTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTAAAAATTAAACTTTTTTTACTTAA
  AACCAATACTCCACTCAAAAAAAATGAACCCAAAAGGCATCCTTTAACCCTGGCCAACAT
  AACTAAGTCCAAAGGAAGCCAAGGGGGGCCCCCATTAACATGCTGGGTTGTATGTAAAAA
  AAAAAAGCCCTCCCCCACCCCGAGCCCTGGCCCCTGGAAAAAAATAAAAAAAGGATTGGG
  CCCTGGGGGAAGAAACCATTAGGGGAAAACTTTGGTTAATGCAGTCGGTTGCCGAAAAGG
  TTGCACCCAAAACCCGAAGCCCCGGCACCCAAAGTAAGTAAGGGGGGGGGGTTAATGGGG
  TAAACCGGGCTCCTTCCCAACACCAGGGGAATACTGGGGTCAGGCATGCTGGGGGAAAAA
  ACCAACCCCGGGTCATTGGGCCCATCCAGTCCATTCAGCCAGGATGTTTCCCCTGCCAAA
  AAGCTTGAGCCTCTCTTTGATTCCCTGAACTCGGGCAGAGGCCAGCGACTAATCAGGCTC
  TCTGTCCGCAAGTCCATGATGGACAGGGAAGCGGGGTGACAAACAACAGGGGCAAAGAAT
  TTTCCCAAAGCCAAGCAAGGGCCAAGTTTTGCTATTTTCAGGAAGCTTGGAGGACCCCTG
  GAAAATATCAAAACGGGGCAAAGCCCCCCTGGGAAGAAAACCAAGGGGCGAAAAAACAGA
  ACAAGGGGTTTTGCCCTAAAAAAGAAGAATTTTGGGGGTGGGGGACAAAACCTTTTTTCC
  TCGAAAACAAAAAAGGTTTTAAGACCTTCAGCGGGGGTTTCTTCCCCAAAGGGGGCCAAA
  CTTAATCCTATATTGGGGCGGCCTTAAAGGGGGAGGACCCCCCAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012164
• ORF Size: 1269 bp
• Insert Size: 1910
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012164.2, NP_036296.1
• RefSeq Size: 1886
• RefSeq ORF: 1269
• Locus ID: 26190
• Domains: WD40, F-box
• Protein Families: Druggable Genome
• Gene Summary: F-box proteins are an expanding family of eukaryotic proteins characterized by an approximately 40 amino acid motif, the F box. Some F-box proteins have been shown to be critical for the ubiquitin-mediated degradation of cellular regulatory proteins. In fact, F-box proteins are one of the four subunits of ubiquitin protein ligases, called SCFs. SCF ligases bring ubiquitin conjugating enzymes to substrates that are specifically recruited by the different F-box proteins. Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats, leucine-rich repeats, or the presence or absence of other protein-protein interacting domains. This gene encodes the second identified member of the F-box gene family and contains multiple WD-40 repeats. [provided by RefSeq, Jul 2008]