FLASH (CASP8AP2) (NM_012115) Human Untagged Clone

CAT#: SC115516

CASP8AP2 (untagged)-Human caspase 8 associated protein 2 (CASP8AP2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CASP8AP2
• Synonyms: CED-4; FLASH; RIP25
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115516 sequence for NM_012115 edited (data generated by NextGen Sequencing)
  ATGGCAGCAGATGATGACAATGGTGATGGAACAAGTTTATTTGATGTCTTTTCTGCTTCT
  CCTCTTAAGAACAATGATGAAGGCTCACTGGACATATACGCTGGGTTGGACAGTGCTGTT
  TCTGACAGCGCTTCCAAATCCTGTGTACCATCAAGAAATTGTTTGGACTTATATGAAGAG
  ATCCTGACTGAAGAAGGAACTGCAAAGGAGGCAACATATAATGATTTGCAAGTAGAATAT
  GGAAAATGTCAACTACAAATGAAAGAGCTGATGAAAAAATTTAAAGAAATACAGACACAG
  AATTTCAGCTTAATAAACGAAAACCAGTCTCTTAAGAAGAATATTTCAGCACTTATCAAA
  ACTGCCAGAGTGGAAATAAACCGCAAGGATGAAGAAATAAGTAATCTTCACCAAAGATTG
  TCTGAGTTTCCACATTTTCGAAATAATCATAAAACTGCAAGGACATTTGATACAGTTAAA
  ACAAAAGATCTTAAATCTAGATCTCCACATTTGGATGATTGTTCAAAGACTGATCACAGA
  GCTAAAAGTGATGTTTCTAAAGATGTACATCATAGCACTTCACTGCCAAATCTGGAAAAG
  GAAGGAAAACCACATTCTGATAAAAGGAGTACTTCACATTTACCTACATCTGTTGAGAAA
  CACTGCACTAATGGTGTTTGGTCACGTTCTCATTATCAGGTTGGCGAGGGTAGCTCAAAT
  GAGGATAGTAGAAGAGGAAGAAAAGATATTAGACATAGCCAGTTTAACAGAGGAACTGAA
  AGAGTACGAAAAGACTTAAGTACTGGCTGTGGTGATGGTGAACCAAGGATATTGGAGGCT
  AGTCAAAGGCTACAAGGACATCCTGAGAAATATGGTAAAGGTGAACCAAAGACTGAAAGC
  AAAAGTTCGAAGTTTAAAAGTAACTCAGATTCTGACTATAAAGGTGAACGCATTAACTCT
  TCTTGGGAGAAAGAGACCCCTGGAGAAAGGTCACACAGTCGAGTAGACTCTCAAAGTGAC
  AAAAAACTAGAAAGACAAAGTGAAAGATCACAAAATATAAATAGGAAAGAAGTTAAATCA
  CAAGACAAAGAAGAAAGAAAAGTTGATCAAAAACCTAAATCAGTAGTAAAGGACCAAGAT
  CACTGGAGAAGATCTGAACGAGCATCACTTCCTCATTCCAAGAATGAAATAACATTTTCT
  CATAATTCAAGTAAATACCATCTAGAAGAGAGAAGAGGATGGGAAGATTGTAAAAGAGAC
  AAGAGTGTAAACAGTCATAGTTTTCAAGATGGAAGATGTCCATCTTCTCTTTCAAACAGT
  AGAACTCACAAAAACATTGACTCTAAGGAAGTTGATGCCATGCATCAGTGGGAAAATACA
  CCTTTAAAAGCAGAAAGACATAGAACTGAAGATAAGAGGAAAAGAGAACAAGAAAGCAAA
  GAAGAAAATAGGCATATTAGAAATGAAAAAAGAGTACCTACAGAACATTTGCAGAAGACT
  AATAAGGAAACTAAGAAAACCACTACTGATTTAAAGAAACAGAATGAACCAAAGACTGAT
  AAGGGAGAAGTCCTTGATAATGGTGTTTCTGAAGGAGCAGATAATAAAGAGCTTGCAATG
  AAAGCTGAGAGTGGTCCAAATGAAACAAAAAACAAGGACCTAAAATTGAGTTTTATGAAA
  AAATTGAACTTAACTCTTTCTCCTGCTAAAAAGCAACCTGTTTCCCAGGATAATCAGCAT
  AAAATAACTGATATTCCCAAGTCCAGTGGTGTATGTGATTCAGAGTCTTCAATGCAAGTT
  AAAACAGTGGCATATGTTCCCTCCATAAGTGAACATATCTTGGGGGAAGCAGCTGTCAGT
  GAACATACCATGGGGGAAACCAAGTCAACGTTATTGGAACCAAAGGTTGCTCTTCTAGCA
  GTGACTGAACCCAGGATCGGTATCTCAGAAACCAACAAGGAAGACGAAAATAGTTTGTTA
  GTTAGGTCTGTTGACAATACTATGCATTGTGAAGAGCCCATTTGTGGTACAGAGACTTCC
  TTCCCATCTCCTATGGAAATACAACAGACAGAATCCTTGTTTCCATCAACAGGAATGAAA
  CAAACCATTAATAATGGAAGGGCAGCAGCTCCTGTGGTAATGGATGTATTACAAACAGAT
  GTGTCTCAAAACTTTGGCTTGGAATTGGATACCAAAAGAAATGATAATTCAGATTATTGT
  GGTATTTCTGAAGGTATGGAGATGAAGGTGGCACTTTCAACAACAGTGAGTGAAACCACT
  GAAAGCATTTTGCAGCCTTCAATTGAGGAAGCTGATATTTTGCCAATAATGCTTTCAGAA
  GATAATAACCCAAAATTTGAGCCTTCTGTTATAGTTACACCACTGGTTGAGAGTAAGTCG
  TGTCATCTGGAGCCTTGCTTACCTAAAGAGACTCTAGATTCTTCACTTCAGCAGACTGAG
  TTAATGGACCACAGAATGGCAACTGGTGAAACAAACTCAGTATATCATGATGATGATAAC
  TCGGTTTTGAGCATTGACCTTAATCACCTGAGACCTATTCCAGAAGCCATCAGTCCTCTG
  AATAGTCCAGTGAGACCTGTAGCAAAAGTTCTTAGAAATGAAAGCCCACCTCAAGTTCCA
  GTGTATAATAACAGTCATAAAGATGTGTTTTTACCAAATTCAGCTCATTCTACCTCTAAG
  AGTCAGTCTGATCTCAATAAGGAAAATCAAAAGCCAATTTACAAATCTGACAAATGTACA
  GAAGCAGACACATGTAAGAATTCACCATTAGATGAATTAGAAGAAGGAGAAATTAGAAGT
  GATAGTGAAACATCTAAACCACAAGAAAGTTTTGAAAAAAATTCCAAACGTAGAGTGTCA
  GCTGATGTGCGGAAGTCAAAGACTATCCCACGACGTGGGAAAAGTACTGTGTGTTTAGAT
  AAAGACAGTAGGAAAACACATGTAAGAATCCATCAGACCAATAACAAATGGAATAAAAGA
  CCTGATAAATCTAGCAGATCTTCAAAAACAGAGAAGAAAGATAAAGTGATGAGCACTTCC
  AGCTTGGAAAAAATAGTTCCAATTATTGCTGTACCCTCTTCTGAACAAGAGATCATGCAC
  ATGTTACGAATGATAAGAAAACATGTAAGAAAAAATTATATGAAATTCAAGGCAAAATTT
  TCATTAATACAATTTCACAGAATTATTGAGTCAGCAATTTTGAGTTTTACATCTTTAATT
  AAACATCTCAACTTACACAAAATCTCTAAGTCAGTGACTACCTTACAGAAGAATCTCTGT
  GATATTATAGAGTCTAAACTTAAGCAAGTTAAAAAGAATGGCATAGTTGATCGTTTATTT
  GAACAGCAACTACCAGATATGGAAAAAAAATTGTGGAAGTTTGTAGATGACCAACTTGAT
  TATTTGTTTGCAAAGCTTAAGAAAATCTTAGTATGTGATTCCAAAAGCTTTGGAAGAGAT
  AGTGATGAAGGCAAACTTGAAAAAACAAGTAAACAGAATGCACAGTATTCAAATAGTCAG
  AAAAGGAGTGTGGACAACTCCAACAGAGAATTGCTGAAAGAAAAATTATCAAAATCAGAA
  GACCCTGTTCATTATAAGTCTTTAGTGGGATGTAAAAAATCTGAGGAAAATTATCAAGAC
  CAAAATAACTCCAGTATTAACACTGTAAAGCATGACATTAAAAAAAATTTTAACATCTGC
  TTTGATAATATAAAGAACTCTCAATCCGAAGAGCGCTCCTTGGAAGTACACTGTCCAAGC
  ACCCCAAAGTCAGAAAAAAACGAAGGAAGCAGCATAGAGGATGCACAGACATCCCAGCAT
  GCAACTTTGAAGCCAGAACGAAGTTTCGAGATTCTTACCGAACAGCAAGCATCGAGCCTT
  ACTTTTAATTTAGTGAGTGATGCACAAATGGGTGAAATATTTAAAAGTTTGTTGCAAGGT
  TCTGATCTTTTAGACAGCAGTGTTAACTGTACTGAAAAAAGTGAGTGGGAGTTAAAGACT
  CCAGAGAAGCAGCTGCTAGAGACTCTTAAGTGCGAGTCTATACCAGCTTGTACAACAGAA
  GAGCTAGTTTCAGGGGTGGCTTCTCCATGTCCTAAAATGATTAGTGATGATAATTGGTCA
  TTATTATCATCTGAAAAAGGTCCATCTCTGTCTTCAGGGCTTTCATTGCCGGTTCATCCT
  GATGTGTTGGATGAAAGTTGTATGTTTGAAGTGTCTACTAACCTACCTTTAAGTAAAGAT
  AATGTGTGTAGTGTAGAAAAGAGCAAGCCCTGCGTTTCTTCCATACTTCTTGAAGATCTA
  GCAGTCTCTTTAACAGTACCATCGCCTCTGAAGTCAGATGGTCATCTCAGTTTTTTAAAG
  CCTGATATGTCGTCCAGTTCAACTCCTGAAGAAGTCATTAGTGCTCATTTTAGTGAAGAT
  GCCTTACTTGAGGAAGAGGATGCATCTGAGCAAGATATTCATTTAGCTCTGGAGTCTGAT
  AATTCAAGCAGTAAATCAAGTTGTTCTTCTTCCTGGACAAGCCGATCTGTTGCTCCAGGC
  TTTCAGTACCACCCTAATCTACCTATGCATGCCGTCATAATGGAAAAGTCCAATGATCAT
  TTCATTGTGAAAATACGACGTGCAACACCATCTACCTCTTCTGGCCTTAAACAGAGTATG
  ATGCCTGATGAATTATTGACATCTTTGCCCAGACATGGAAAGGAAGCTGATGAAGGACCA
  GAGAAAGAATATATTTCATGTCAGAACACAGTTTTTAAATCTGTGGAGGAATTGGAAAAC
  TCCAACAAAAATGTTGATGGCAGCAAGTCAACTCATGAAGAACAGAGCTCTATGATACAA
  ACACAGGTTCCTGATATATATGAATTTCTTAAAGATGCTTCAGATAAGATGGGTCATAGT
  GATGAAGTGGCTGATGAATGTTTCAAATTGCATCAAGTATGGGAAACAAAAGTGCCTGAA
  AGCATTGAAGAATTGCCTTCAATGGAAGAAATCTCACACTCTGTTGGGGAACATCTTCCA
  AACACATACGTAGATCTAACGAAAGATCCAGTCACTGAAACCAAAAACTTGGGGGAATTC
  ATAGAAGTAACAGTTTTACATATTGATCAGTTGGGATGTTCTGGAGGCAATTTAAATCAG
  AGTGCTCAAATATTAGACAATTCTTTGCAGGCTGATACTGTAGGTGCTTTTATTGATTTG
  ACACAAGATGCTTCAAGTGAGGCTAAAAGTGAAGGTAATCATCCTGCATTAGCTGTGGAA
  GACTTGGGATGTGGGGTGATACAGGTAGATGAAGATAATTGTAAGGAAGAAAAGGCACAA
  GTGGCAAACAGGCCTTTAAAATGCATTGTTGAGGAAACCTATATCGACTTGACCACAGAA
  TCTCCCAGTTCATGTGAAGTAAAAAAAGATGAGTTAAAATCAGAGCCAGGATCAAATTGT
  GATAACTCGGAGTTGCCTGGGACTTTGCATAATTCTCACAAAAAGAGAAGAAACATTTCT
  GATCTAAATCATCCTCATAAAAAACAAAGAAAGGAAACAGACTTAACTAATAAGGAAAAG
  ACCAAGAAACCTACCCAAGATTCTTGTGAGAATACTGAAGCTCACCAAAAGAAAGCCAGT
  AAGAAGAAGGCCCCTCCTGTGACTAAAGATCCCTCATCATTAAAGGCAACCCCAGGGATT
  AAGGATTCATCAGCAGCACTTGCCACTTCTACAAGTCTTTCTGCAAAAAATGTTATTAAA
  AAGAAGGGAGAAATTATCATTTTATGGACAAGAAATGATGACCGGGAAATTTTATTGGAG
  TGTCAGAAAAGAGGGCCATCATTTAAAACATTTGCATATTTAGCCGCCAAGTTGGATAAA
  AATCCAAATCAGGTCTCAGAAAGATTCCAGCAGCTAATGAAGCTCTTTGAAAAGTCAAAA
  TGCAGATAA
  
  Clone variation with respect to NM_012115.3
  3382 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_012115 unedited
  CAGAATTTTGTAATACGACTCACTATTAGGGCGGCCGCGAATTCGCACCAGCTTGGGCCG
  GGCAGGGCGGGTAAGTTGTCGTAGGGGCCCGGTCCGTGAGGGACTGCTAAGGAAGAGGCT
  GCATGGCGCGGTAGTCCCCCGAGTGGAGGTCGGCTGCCCCTGGGAAACCAGAGAGTCGGA
  GGGAGTCCATCTGGAGCGGCCAAGTGGTGACTCTCAAAAGGAAATAGGATCATGGCAGCA
  GATGATGACAATGGTGATGGAACAAGTTTATTTGATGTCTTTTCTGCTTCTCCTCTTAAG
  AACAATGATGAAGGCTCACTGGACATATACGCTGGGTTGGACAGTGCTGTTTCTGACAGC
  GCTTCCAAATCCTGTGTACCATCAAGAAATTGTTTGGACTTATATGAAGAGATCCTGACT
  GAAGAAGGAACTGCAAAGGAGGCAACATATAATGATTTGCAAGTAGAATATGGAAAATGT
  CAACTACAAATGAAAGAGCTGATGAAAAAATTTAAAGAAATACAGACACAGAATTTCAGC
  TTAATAAACGAAAACCAGTCTCTTAAGAAGAATATTTCAGCACTTATCAAAACTGCCAGA
  GTGGAAATAAACCGCAAGGATGAAGAAATAAGTAATCTTCACCAAAGATTGTCTGAGTTT
  CCACATTTTCGAAATAATCATAAAACTGCAAGGACATTTGATACAGTTAAAACAAAAGAT
  CTTAAATCTAGATCTNCACATTTGGATGATTGTTCANAGACTGATCACAGAGCTAAAAGT
  GATGTTTCTAAAGATGTACATCATAGCACTTCACTGCCAAATCTGGNAAAGGAGGNANAC
  CACATTCTGATANAGGAGTACTTCACATTACCTACATCTGNTGAGAACACTGCACTATGG
  TGTTGGGTCACGTCTCATATCAGNNTGCGAGGTAGCTCAATGAGNTAGTANA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_012115
• ORF Size: 5949 bp
• Insert Size: 6500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_012115.2, NP_036247.1
• RefSeq Size: 6782
• RefSeq ORF: 5949
• Locus ID: 9994
• Protein Families: Druggable Genome
• Gene Summary: This protein is highly similar to FLASH, a mouse apoptotic protein identified by its interaction with the death-effector domain (DED) of caspase 8. Studies of FLASH protein suggested that this protein may be a component of the death-inducing signaling complex that includes Fas receptor, Fas-binding adapter FADD, and caspase 8, and plays a regulatory role in Fas-mediated apoptosis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Nov 2008]
  Transcript Variant: This variant (1) represents the longest transcript.