SEC63 (NM_007214) Human Untagged Clone

CAT#: SC115637

SEC63 (untagged)-Human SEC63 homolog (S. cerevisiae) (SEC63)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SEC63
• Synonyms: DNAJC23; ERdj2; PCLD2; PRO2507; SEC63L
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_007214, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCCGGGCAGCAGTTCCAGTACGATGACAGTGGGAACACCTTCTTCTACTTCCTCACCTCCTTCGTGG
  GGCTCATCGTGATCCCGGCGACATACTACCTCTGGCCCCGAGATCAGAATGCCGAGCAAATTCGATTAAA
  GAATATCAGAAAAGTATATGGAAGGTGTATGTGGTATCGTTTACGGTTATTAAAACCCCAGCCAAATATT
  ATTCCTACAGTAAAGAAAATAGTTCTGCTTGCAGGATGGGCATTGTTCTTATTCCTTGCATATAAAGTTT
  CCAAAACAGACCGAGAATACCAAGAATACAATCCTTATGAAGTATTAAATTTGGATCCTGGAGCCACAGT
  AGCAGAAATTAAAAAACAATATCGTTTGCTGTCACTTAAATATCATCCAGATAAAGGAGGTGATGAGGTT
  ATGTTCATGAGGATAGCAAAAGCTTATGCTGCTTTAACGGATGAAGAGTCCCGGAAAAATTGGGAAGAAT
  TTGGAAATCCAGATGGGCCTCAAGCCACAAGCTTTGGAATTGCCCTGCCAGCTTGGATAGTTGACCAGAA
  AAACTCAATTCTGGTTTTACTTGTATATGGATTGGCATTTATGGTTATCCTTCCAGTTGTTGTGGGCTCT
  TGGTGGTATCGCTCAATACGCTATAGTGGAGACCAGATTCTAATACGCACAACACAGATTTATACATACT
  TTGTTTATAAAACCCGAAATATGGATATGAAACGTCTTATCATGGTTTTGGCTGGAGCTTCTGAATTTGA
  TCCTCAGTATAATAAAGATGCCACAAGCAGACCAACGGATAATATTCTAATACCACAGCTAATCAGAGAA
  ATTGGCAGCATTAATTTAAAGAAGAATGAGCCTCCACTTACCTGCCCATATAGCCTGAAGGCCAGAGTTC
  TTTTACTGTCTCATCTTGCTAGAATGAAAATTCCTGAGACCCTTGAAGAAGATCAGCAATTCATGCTAAA
  AAAGTGTCCTGCCCTACTTCAAGAAATGGTTAATGTAATCTGCCAACTAATAGTAATGGCCCGGAACCGT
  GAAGAAAGGGAGTTTCGTGCTCCAACTTTGGCATCCCTAGAAAACTGCATGAAGCTTTCTCAGATGGCCG
  TTCAGGGACTTCAGCAATTTAAGTCTCCCCTTCTGCAGCTCCCTCATATTGAAGAGGACAATCTTAGACG
  GGTTTCTAATCATAAGAAGTATAAAATTAAAACTATCCAGGATTTGGTGAGTTTAAAAGAATCAGATCGT
  CACACTCTACTGCACTTCCTTGAAGATGAAAAATATGAAGAGGTTATGGCTGTCCTTGGGAGTTTTCCAT
  ATGTGACCATGGATATAAAATCACAGGTGTTAGATGATGAAGATAGCAACAACATCACAGTAGGATCCTT
  AGTTACAGTGTTGGTTAAGTTGACAAGGCAAACAATGGCTGAAGTATTTGAAAAGGAGCAGTCCATCTGT
  GCTGCAGAGGAACAGCCAGCAGAAGATGGGCAGGGTGAAACTAACAAGAACAGGACAAAAGGAGGATGGC
  AACAGAAGAGTAAAGGACCCAAGAAAACTGCTAAATCAAAAAAAAAGAAACCTTTAAAAAAAAAACCTAC
  ACCTGTGCTATTACCACAGTCAAAGCAACAGAAACAAAAGCAGGCAAATGGAGTCGTTGGGAATGAAGCT
  GCAGTAAAGGAAGATGAAGAAGAAGTTTCAGATAAGGGCAGTGATTCTGAAGAAGAAGAAACCAATAGAG
  ATTCCCAAAGTGAGAAAGATGATGGTAGTGACAGAGACTCTGATAGAGAGCAAGATGAAAAACAAAACAA
  AGATGATGAAGCAGAGTGGCAAGAATTACAACAAAGCATACAGCGAAAAGAGAGAGCTCTATTGGAAACC
  AAATCAAAAATAACACATCCTGTGTATAGCCTTTACTTTCCTGAGGAAAAACAAGAATGGTGGTGGCTTT
  ACATTGCAGATAGGAAGGAGCAGACATTAATATCCATGCCATATCATGTGTGTACGCTGAAAGATACAGA
  GGAGGTAGAGCTGAAGTTTCCTGCACCAGGCAAGCCTGGAAATTATCAGTATACTGTGTTTCTGAGATCA
  GACTCCTATATGGGTTTGGATCAGATTAAACCATTGAAGTTGGAAGTTCATGAGGCTAAGCCTGTGCCAG
  AAAATCACCCACAGTGGGATACAGCAATAGAGGGGGATGAAGACCAGGAGGACAGTGAGGGCTTTGAAGA
  TAGCTTTGAGGAAGAAGAGGAGGAAGAAGAAGATGATGACTAA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_007214 unedited
  AACGTCGATTATTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGGGAGT
  GCAGAGCGTGGTCGTGGCGGCGGCGGTGAGAAGAGCGAGGCGGAGGAGGGGGTGCCATGG
  CCGGGCAGCAGTTCCAGTACGATGACAGTGGGAACACCTTCTTCTACTTCCTCACCTCCT
  TCGTGGGGCTCATCGTGATCCCGGCGACATACTACCTCTGGCCCCGAGATCAGAATGCCG
  AGCAAATTCGATTAAAGAATATCAGAAAAGTATATGGAAGGTGTATGTGGTATCGTTTAC
  GGTTATTAAAACCCCAGCCAAATATTATTCCTACAGTAAAGAAAATAGTTCTGCTTGCAG
  GATGGGCATTGTTCTTATTCCTTGCATATAAAGTTTCCAAAACAGACCGAGAATACCAAG
  AATACAATCCTTATGAAGTATTAAATTTGGATCCTGGAGCCACAGTAGCAGAAATTAAAA
  AACAATATCGTTTGCTGTCACTTAAATATCATCCAGATAAAGGAGGTGATGAGGTTATGT
  TCATGAGGATAGCAAAAGCTTATGCTGCTTTAACGGATGAAGAGTCCCGGANAAATTGNG
  AAGAATTTGGAAATCCAGATGGGCCTCAAGCCACAAGCTTTGGAATTGCCCTGCCAGCTT
  GGATAGTTGACCAGAAAAATTCAATTCTGGTTTTACTTGTATATGGATTGGCANTTATGG
  TTATCCTTCCAGTTGTTGTGGGCTCTTGGTGGTATCGCTCAATACGCTATAGTGGAGACC
  AGATTCTAATACGCACAACACANGATTATACATACTTTGGTTATAAAACCCGAATATGGA
  TATGAAACGTCTTATCATGGTTTTGGCTGGAGCTTCTGAATTTGATCCCTCAGTATATAA
  AGATGCCACAAGCGACCACCG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_007214 unedited
  GCACGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTTTTTAACGAGTCAACAAACTTC
  TATTTTTATTGACAGGAGTCCAAAATGAATACAAAAAAAGCTTCCTTTGCATGTTATACT
  TACTTTCCTTAAAAAGCTCCTGATAGAGTCAAGTAGACTGAAAACTAAGGATGTAGTTCA
  GCTTTTAGAGTGAACCTTTTTTAAAAAAGGTTTAATAACATAAGCCACCAGTATCAGAAA
  ACATACAGTCCCACTATCACTTTTAGAGCTAGAACTTATCAAAAGAATTAGATCCTGCAT
  TGATCTGCTAAGATAGAGGTTTAGAAATGGTTTAAGCCATTAAAAGCCATTTTTATAATC
  TGTCTGATAACTCTGGGCAATTAAGAAAAGGAAAATTCCAAAACGTAGCCCTCTATATCA
  TGTGGAATGTGAGAGAATGCCAACTTATGACCAAGATAAGTAAAAATAAAAGTTTAAATC
  TATGAGTGGAGCTGTTGTATCACTGCAAAATGTCAACAACAGAGCTTATCAAGAGATTAT
  CAACTTGAGCGATGTTACTTAAACTTGAGCGATGTTACTTAAAACATATTTGAGGAGTTT
  GCTAAAACTAAAGCTGAACAAAGAAAAGTCGCTCATTTACAGACTGTGTTTCCTGCATCT
  TTACTTTTACTGGGACCATAGACTGATNCAGATATACATAGCCCACACTTCTGGACAGTT
  ANTATAACAAAGGATTTATTATCATTTGCAGATGAAATAAATGTACCATCCCCTACTTGA
  AAGGTTTCAATAAGCCTTACATTCTTCAGGTTGTACCAAGCACCGCACTGNCTAGTTATA
  TATGCACCATTNCTAGATANAAAACTACCCTNCCTCAAATCAGTTCTGTACTGTTNCTGG
  TNATGATACACTTCATACAGCAAAAATGCAATTGTGCAACACTGGGNNCATTCAGAGACT
  GCTAGNCTCATCTCTCTCN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_007214
• ORF Size: 2283 bp
• Insert Size: 3240
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_007214.3, NP_009145.1
• RefSeq Size: 3850
• RefSeq ORF: 2283
• Locus ID: 11231
• Domains: DnaJ, Sec63
• Protein Families: Transmembrane
• Gene Summary: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC62 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER. [provided by RefSeq, Jul 2008]