TUSC3 (NM_006765) Human Untagged Clone

CAT#: SC115915

TUSC3 (untagged)-Human tumor suppressor candidate 3 (TUSC3), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TUSC3
• Synonyms: D8S1992; M33; MagT2; MRT7; MRT22; N33; OST3A; SLC58A2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC115915 sequence for NM_006765 edited (data generated by NextGen Sequencing)
  ATGGGGGCCCGGGGCGCTCCTTCACGCCGTAGGCAAGCGGGGCGGCGGCTGCGGTACCTG
  CCCACCGGGAGCTTTCCCTTCCTTCTCCTGCTGCTGCTGCTCTGCATCCAGCTCGGGGGA
  GGACAGAAGAAAAAGGAGAATCTTTTAGCTGAAAAAGTAGAGCAGCTGATGGAATGGAGT
  TCCAGACGCTCAATCTTCCGAATGAATGGTGATAAATTCCGAAAATTTATAAAGGCACCA
  CCTCGAAACTATTCCATGATTGTTATGTTCACTGCTCTTCAGCCTCAGCGGCAGTGTTCT
  GTGTGCAGGCAAGCTAATGAAGAATATCAAATACTGGCGAACTCCTGGCGCTATTCATCT
  GCTTTTTGTAACAAGCTCTTCTTCAGTATGGTGGACTATGATGAGGGGACAGACGTTTTT
  CAGCAGCTCAACATGAACTCTGCTCCTACATTCATGCATTTTCCTCCAAAAGGCAGACCT
  AAGAGAGCTGATACTTTTGACCTCCAAAGAATTGGATTTGCAGCTGAGCAACTAGCAAAG
  TGGATTGCTGACAGAACGGATGTTCATATTCGGGTTTTCAGACCACCCAACTACTCTGGT
  ACCATTGCTTTGGCCCTGTTAGTGTCGCTTGTTGGAGGTTTGCTTTATTTGAGAAGGAAC
  AACTTGGAGTTCATCTATAACAAGACTGGTTGGGCCATGGTGTCTCTGTGTATAGTCTTT
  GCTATGACTTCTGGCCAGATGTGGAACCATATCCGTGGACCTCCATATGCTCATAAGAAC
  CCACACAATGGACAAGTGAGCTACATTCATGGGAGCAGCCAGGCTCAGTTTGTGGCAGAA
  TCACACATTATTCTGGTACTGAATGCCGCTATCACCATGGGGATGGTTCTTCTAAATGAA
  GCAGCAACTTCGAAAGGCGATGTTGGAAAAAGACGGATAATTTGCCTAGTGGGATTGGGC
  CTGGTGGTCTTCTTCTTCAGTTTTCTACTTTCAATATTTCGTTCCAAGTACCACGGCTAT
  CCTTATAGTGATCTGGACTTTGAGTGA
  
  Clone variation with respect to NM_006765.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006765 unedited
  TGTATACGACTCCTATAGGGCGGCCGCGATTCGGCACGAGGGTCTCCTCCTCTGCGTCCT
  CGGCCGCGGCCCGGGTCCCTCGCAAAGCCGCTGCCATCCCGGAGGGCCCAGCCAGCGGGC
  TCCCGGAGGCTGGCCGGGCAGGCGTGGTGCGCGGTAGGAGCTGGGCGCGCACGGCTACCG
  CGCGTGGAGGAGACACTGCCCTGCCGCGATGGGGGCCCGGGGCGCTCCTTCACGCCGTAG
  GCAAGCGGGGCGGCGGCTGCGGTACCTGCCCACCGGGAGCTTTCCCTTCCTTCTCCTGCT
  GCTGCTGCTCTGCATCCAGCTCGGGGGAGGACAGAAGAAAAAGGAGAATCTTTTAGCTGA
  AAAAGTAGAGCAGCTGATGGAATGGAGTTCCAGACGCTCAATCTTCCGAATGAATGGTGA
  TAAATTCCGAAAATTTATAAAGGCACCACCTCGAAACTATTCCATGATTGTTATGTTCAC
  TGCTCTTCAGCCTCAGCGGCAGTGTTCTGTGTGCAGGCAAGCTAATGAAGAATATCAAAT
  ACTGGCGAACTCCTGGCGCTATTCATCTGCTTTTTGTAACAAGCTCTTCTTCAGTATGGT
  GGACTATGATGAGGGGACAGACGTTNTTCAGCAGCTCAACATGAACTCTGCTCCTACATT
  CATGCATTTTCCTCCAAAGGGCAGACCTAAGAGAGCTGATACTTTTTGACCTCCAAAGAA
  TGGNATTTGCAGCTGAGCCACTAGCANAGTGGNATTGCTGACAGAACGGATGTTCATATT
  CGGGGTTTCAAGACACCCCACTACTCTGGTACCATTGCTTTTNCCCTGNTANTGGTCCCT
  GGTTGGAGGGTTGCTTTATTTGAGAAGGAACACCTTGGAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006765 unedited
  GGCAACTTTCCAGGNCCAGGNATAGCACTGGGGAGGGGTCACAGGATGCCACCCGGGATC
  TGTTCAGGAAACAGCTATGACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTT
  TTCATAATTACATTGTCATTTATTTCAATCCTGTGGCACACACTGAATATAACAGGCTTG
  AAAAACACTTTGATATTTCCTTTGTAGATTACTAAATGCTACCATTGATTTCTGTAAATT
  AAATTTACTAGGAAAACCCACAGTTTAAAAAAAGTACACAAGAATAAGCTAGCTGATCAC
  AATGAAATGAATGAATTCAAAATAGTATAAAGTCAGGAACAGTTTATCTTCATGGTAAAC
  ATTCACTTTATGCAAATCCCACTTGGCTTCATTTAATTAAAAAGCTGAGGTTATAGNNNT
  TTTAAGTGCCATGGTCCAAATCACATCTTCTCACTCAAAGTCCAGATCACTATAAGGATA
  GCCGTGGTACTTGGAACGAAATATTGAAAGTAGAAAACTGAAGAAGAAGACCACCAGGCC
  CAATCCCACTAGGCAAATTATCCGTCTTTTTCCAACATCGCCTTTCGAAGTTGCTGCTTC
  ATTTAGAAGAACCATCCCCATGGTGATAGCGGCATTCAGTACCAGAATAATGTGTGATTC
  TGCCACAACTGAGCCTGGCTGCTCCATGAAGTAGCTCACTTGCCATTTGTGGGTTCTATG
  AGCTATTTTNNNCTCCGATATGTTCCACTCTGCCAAAGTCATAGCAAACTATCCAGAGAC
  CATGGCCACCAGTCTGTATAGAGAACTCAGTTGTTCTCTCAATAAGCAACCTCACAGCGA
  ACTACAGGGCAGCATGTACAGATATTGGTGTCTGAAACCGATGAACTTCGCTGCA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006765
• ORF Size: 1047 bp
• Insert Size: 1570
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006765.2, NP_006756.2
• RefSeq Size: 1613
• RefSeq ORF: 1047
• Locus ID: 7991
• Domains: OST3_OST6
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Metabolic pathways, N-Glycan biosynthesis
• Gene Summary: This gene encodes a protein that has been associated with several biological functions including cellular magnesium uptake, protein glycosylation and embryonic development. This protein localizes to the endoplasmic reticulum and acts as a component of the oligosaccharyl transferase complex which is responsible for N-linked protein glycosylation. This gene is a candidate tumor suppressor gene. Homozygous mutations in this gene are associated with autosomal recessive nonsyndromic mental retardation-7 and in the proliferation and invasiveness of several cancers including metastatic pancreatic cancer, ovarian cancer and glioblastoma multiform. [provided by RefSeq, Oct 2017]
  Transcript Variant: This variant (1) represents the longer transcript, and encodes the longer isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.