AGR2 (NM_006408) Human Untagged Clone

CAT#: SC116098

AGR2 (untagged)-Human anterior gradient homolog 2 (Xenopus laevis) (AGR2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AGR2
• Synonyms: AG-2; AG2; GOB-4; HAG-2; HEL-S-116; HPC8; PDIA17; XAG-2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116098 sequence for NM_006408 edited (data generated by NextGen Sequencing)
  ATGGAGAAAATTCCAGTGTCAGCATTCTTGCTCCTTGTGGCCCTCTCCTACACTCTGGCC
  AGAGATACCACAGTCAAACCTGGAGCCAAAAAGGACACAAAGGACTCTCGACCCAAACTG
  CCCCAGACCCTCTCCAGAGGTTGGGGTGACCAACTCATCTGGACTCAGACATATGAAGAA
  GCTCTATATAAATCCAAGACAAGCAACAAACCCTTGATGATTATTCATCACTTGGATGAG
  TGCCCACACAGTCAAGCTTTAAAGAAAGTGTTTGCTGAAAATAAAGAAATCCAGAAATTG
  GCAGAGCAGTTTGTCCTCCTCAATCTGGTTTATGAAACAACTGACAAACACCTTTCTCCT
  GATGGCCAGTATGTCCCCAGGATTATGTTTGTTGACCCATCTCTGACAGTTAGAGCCGAT
  ATCACTGGAAGATATTCAAACCGTCTCTATGCTTACGAACCTGCAGATACAGCTCTGTTG
  CTTGACAACATGAAGAAAGCTCTCAAGTTGCTGAAGACTGAATTGTAA
  
  Clone variation with respect to NM_006408.3
  441 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006408 unedited
  TTTAGCATATTTGTATACGACTTCACTATAGGCGGCCCGCGAATTCGCACGAGGCGCATC
  CTAGCCGCCGACTCACACAAGGCAGGTGGGTGAGGAAATCCAGAGTTGCCATGGGAGAAA
  ATTCCAGTGTCAGCATTCTTGCTCCTTGTGGCCCTCTCCTACACTCTGGCCAGAGATACC
  ACAGTCAAACCTGGAGCCAAAAAGGACACAAAGGACTCTCGACCCAAACTGCCCCAGACC
  CTCTCCAGAGGTTGGGGTGACCAACTCATCTGGACTCAGACATATGAAGATGCTCTATAT
  AAATCCAAGACAAGCAACAAACCCTTGATGATTATTCATCACTTGGATGAGTGCCCACAC
  AGTCAAGCTTTAAAGAAAGTGTTTGCTGAAAATAAAGAAATCCAGAAATTGGCAGAGCAG
  TTTGTCCTCCTCAATCTGGTTTATGAAACAACTGACAAACACCTTTCTCCTGATGGCCAG
  TATGTCCCCAGGATTATGTTTGTTGACCCATCTCTGACAGTTAGAGCCGATATCACTGGA
  AGATATTCAAACCGTCTACATGCTTACGAACCTGCAGATACAGCTCTGTTGCTTGACAAC
  ATGAAGAAAGCTCTCAAGTTGCTGAAGACTGAATTGTAAAGATAAAAAATCTTCAAGCCC
  TTTTGTCTGTCAAGCCCTTGAGACTTGAAACCAGAAGAAGTGTGAGAAGACCGCCTAGTG
  TGGAAGCATAGCGAACACCCCTGATAAGGTATGGTTTAATGTTACAACAACTATTTTTTT
  AAAAAAACAAGCTTTTAAACATTTGGGTTCAAGTGTACATGGTGTGAAACCAATATTGTA
  TACTACCATAGGGAGCCACGATTTTTCAAAAAAAAAATAATGTTTGGGCGGTGTCCTGGT
  TTTTCCAAAAAAAAAAAAAAAACTCCCTCTAAATGCCGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006408 unedited
  CGCAATCTATAGTCGAGTTTTTTTTTTTTTTTTTTTGGAGAAAACAGAACACCCCCAAAA
  CATTTATTTTTTTTTTTAGAAAATCATGGCTCACTATGGTAGTATACAATATTGTTTTCA
  CACATGTACACTTGAAACCAAATTTCTAAAACTTGTTTTTCTTAAAAAATAGTTGTTGTA
  ACATTAAACCATAACCTAATCAGTGTGTTCACTATGCTTCCACACTAGCCAGTCTTCTCA
  CACTTCTTCTGGTTTCAAGTCTCAAGGCCTGACAGACAGAAGGGCTTGGAGATTTTTTTT
  CTTTACAATTCAGTCTTCAGCAACTTGAGAGCTTTCTTCATGTTGTCAAGCAACAGAGCT
  GTATCTGCAGGTTCGTAAGCATAGAGACGGTTTGAATATCTTCCAGTGATATCGGCTCTA
  ACTGTCAGAGATGGGTCAACAAACATAATCCTGGGGACATACTGGCCATCAAGAGAAAGG
  TGTTTGTCAGTTGTTTCATAAACCAGATTGAGGAGGACAAACTGCTCTGCCAATTTCTGG
  ATTTCTTTATTTTCAGCAAACACTTTCTTTAAAGCTTGACTGTGTGGGCACTCATCCAAG
  TGATGAATAATCATCAAAGGTTTGTTGCTTGTCTTGGATTTATATAGAGCTTCTTCATAT
  GTCTGAGTCCAGATGAGTTGGTCACCCCAACCTCTGGAGAGGGTCTGGGGCACTTTGGGT
  CCAGAGCCCTTGTGTCCTTTTTGGCCTCCAGNTTGACTGGGGATTCTTTGCCAAAGTGTA
  TGAGAGGCCCCAAGGAACCAGATGCTGACCTTGGATTTTTCCATGCAACTTTGGATTTCT
  CACCCACCTCCTTGTGTATTCCGCGGCTAGATGCCCCTTTGCCCAATTTCGGCCGCCTAT
  TTGAGTGTATACAAATCTGACGGCACTAACAACTTGCTTTATAACCCCACGAACCCCACG
  CCTTTTGGTAAGGGCGGGTTTTCATT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006408
• ORF Size: 528 bp
• Insert Size: 890
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006408.2, NP_006399.1
• RefSeq Size: 1701
• RefSeq ORF: 528
• Locus ID: 10551
• Protein Families: Secreted Protein
• Gene Summary: This gene encodes a member of the disulfide isomerase (PDI) family of endoplasmic reticulum (ER) proteins that catalyze protein folding and thiol-disulfide interchange reactions. The encoded protein has an N-terminal ER-signal sequence, a catalytically active thioredoxin domain, and a C-terminal ER-retention sequence. This protein plays a role in cell migration, cellular transformation and metastasis and is as a p53 inhibitor. As an ER-localized molecular chaperone, it plays a role in the folding, trafficking, and assembly of cysteine-rich transmembrane receptors and the cysteine-rich intestinal gylcoprotein mucin. This gene has been implicated in inflammatory bowel disease and cancer progression. [provided by RefSeq, Mar 2017]