MST1 (STK4) (NM_006282) Human Untagged Clone

CAT#: SC116189

STK4 (untagged)-Human serine/threonine kinase 4 (STK4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: STK4
• Synonyms: KRS2; MST1; YSK3
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_006282 edited
  ATGGAGACGGTACAGCTGAGGAACCCGCCGCGCCGGCAGCTGAAAAAGTTGGATGAAGAT
  AGTTTAACCAAACAACCAGAAGAAGTATTTGATGTCTTAGAGAAACTTGGAGAAGGGTCC
  TATGGCAGCGTATACAAAGCTATTCATAAAGAGACCGGCCAGATTGTTGCTATTAAGCAA
  GTTCCTGTGGAATCAGACCTCCAGGAGATAATCAAAGAAATCTCTATAATGCAGCAATGT
  GACAGCCCTCATGTAGTCAAATATTATGGCAGTTATTTTAAGAACACAGACTTATGGATC
  GTTATGGAGTACTGTGGGGCTGGTTCTGTATCTGATATCATTCGATTACGAAATAAAACG
  TTAACAGAAGATGAAATAGCTACAATATTACAATCAACTCTTAAGGGACTTGAATACCTT
  CATTTTATGAGAAAAATACACCGAGATATCAAGGCAGGAAATATTTTGCTAAATACAGAA
  GGACATGCAAAACTTGCAGATTTTGGGGTAGCAGGTCAACTTACAGATACCATGGCCAAG
  CGGAATACAGTGATAGGAACACCATTTTGGATGGCTCCAGAAGTGATTCAGGAAATTGGA
  TACAACTGTGTAGCAGACATCTGGTCCCTGGGAATAACTGCCATAGAAATGGCTGAAGGA
  AAGCCCCCTTATGCTGATATCCATCCAATGAGGGCAATCTTCATGATTCCTACAAATCCT
  CCTCCCACATTCCGAAAACCAGAGCTATGGTCAGATAACTTTACAGATTTTGTGAAACAG
  TGTCTTGTAAAGAGCCCTGAGCAGAGGGCCACAGCCACTCAGCTCCTGCAGCACCCATTT
  GTCAGGAGTGCCAAAGGAGTGTCAATACTGCGAGACTTAATTAATGAAGCCATGGATGTG
  AAACTGAAACGCCAGGAATCCCAGCAGCGGGAAATGGACCAGGACGATGAAGAAAACTCA
  GTGAGTGGCAGCCGTTGCTGTGGGCCTCAGACATTGATGCTTGTTATTTTATGATTGCCA
  AACCAGGTAAGATGAGTAGGAGGTATTGGATCAACTTGGAGCTGGAGATGCTTCCAGCAT
  AACTATGTCCTAACCTGGATCAACGCATGCTAGAGGGTTGTTGTATCTGTGCTTATTCTT
  CTCCCAGTGCTTCCTAAAACACTTTTAAATTTTACTCTTTGCCCCTCTTTTACTCAATTT
  AACTTTTTATTTTAGAGAGAGAATGCTCAGGTCTGGGACTTGGCTTTTCATATCCTTTTG
  GGGAATCTGGGATCCATACTTAACATGTAGCTTTTACATTTATAGACTTCCTCACAACCC
  TGAGATTCCAAAGATGTTCACATGAGTTTCTTAGATCTATGTCACAAAACTCTATTAAGA
  AGAGTAGAGGAAGAATTCCTTTAGGGTTAGATACACTGCTTATTATCACGTGGATAAATT
  TGTCTTCTTTGCTTAAGTAACAGCGCTTTCATTTCTGGAAGGTGAGTTTAGGACCTGAAT
  AAGTGTTAAATCTCGAAATATTTTCACTAAGACAGGTAGTAGTTATTCAGAAAACTCAAA
  GTCTTTTGTCAAATTAGCCCCAATTTGAGATTGTATCCTTTTACAGGAAGAGGATGAAAT
  GGATTCTGGCACGATGGTTCGAGCAGTGGGTGATGAGATGGGCACTGTCCGAGTAGCCAG
  CACCATGACTGATGGAGCCAATACTATGATTGAGCACGATGACACGTTGCCATCACAACT
  GGGCACCATGGTGATCAATGCAGAGGATGAGGAAGAGGAAGGAACTATGAAAAGAAGGGA
  TGAGACCATGCAGCCTGCGAAACCATCCTTTCTTGAATATTTTGAACAAAAAGAAAAGGA
  AAACCAGATCAACAGCTTTGGCAAGAGTGTACCTGGTCCACTGAAAAATTCTTCAGATTG
  GAAAATACCACAGGATGGAGACTACGAGTTTCTTAAGAGTTGGACAGTGGAGGACCTTCA
  GAAGAGGCTCTTGGCCCTGGACCCCATGATGGAGCAGGAGATTGAAGAGATCCGGCAGAA
  GTACCAGTCCAAGCGGCAGCCCATCCTGGATGCCATAGAGGCTAAGAAGAGACGGCAACA
  AAACTTCTGAGCAAGGCCAGGCTGTGAGGGCCCCAGCTCCACCCAG
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006282 unedited
  NNGTTTAGATTTGTATACGACTTCTATAGGCGGCCGCGNAATTCGCACGAGGGCGGGCTC
  AGGAGGTCCGCGGGAGGATGGAGCAGTGAGCGGGTCTGGGCGGCTGCTGGCAGCGCCATG
  GAGACGGTACAGCTGAGGAACCCGCCGCGCCGGCAGCTGAAAAAGTTGGATGAAGATAGT
  TTAACCAAACAACCAGAAGAAGTATTTGATGTCTTAGAGAAACTTGGAGAAGGGTCCTAT
  GGCAGCGTATACAAAGCTATTCATAAAGAGACCGGCCAGATTGTTGCTATTAAGCAAGTT
  CCTGTGGAATCAGACCTCCAGGAGATAATCAAAGAAATCTCTATAATGCAGCAATGTGAC
  AGCCCTCATGTAGTCAAATATTATGGCAGTTATTTTAAGAACACAGACTTATGGATCGTT
  ATGGAGTACTGTGGGGCTGGTTCTGTATCTGATATCATTCGATTACGAAATAAAACGTTA
  ACAGAAGATGAAATAGCTACAATATTACAATCAACTCTTAAGGGACTTGAATACCTTCAT
  TTTATGAGAAAAATACACCGAGATATCAAGGCAGGAAATATTTTGCTAAATACAGAAGGA
  CATGCAAAACTTGCAGATTTTGGGGTAGCAGGTCAACTTACAGATACCATGGCCAAGCGG
  AATACAGTGATAGGAACACCATTTTGGATGGCTCCAGAAGTGATTCAGGAAATTGGATAC
  AACTGTGTAGCAGACATCTGGNTCCCTTGGAATAACTGCCATAGAAATGGCTGAAGGAAA
  AGCCCCTTATGCTGATATCCATCCAATGAGGGGCATCTTTCATGATTCTACAAATNCTNC
  TNCCACATTTNCGAAACCAGAGCTATGGTCAGATAACTTTACAGATTTTGTGAAACAGTG
  TCTTGTNAAGAAGCCTGAGCA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006282 unedited
  GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAAAGTCTTCCAGAAA
  GACAATTGAAAGCTATTGGGAGAAGAAAAACAGACAATGTAAAACTTTCCCAGCTATCAC
  TCAACTAGGAGTCTCTGTTCCTGGGGTTTAAAACTCTGAGTTAAAAGCGCCAATATAAAT
  CCTTTGAGATAATATACCTGACCAATGTACATACACACATCAAGATGGCACGCTGACTGT
  CAAGAGAGCCCTTCCCACTGGCGCACATTCCTGAGTTCACAAAGGTGCTGTGGAGAGACG
  ACAGAGCAGAAGTGCTGGCTAACAAACATGAGGCAAGCCATCCAGAATTCACCCAAAGCC
  TGGGTGGAGCTGGGGCCCTCACAGCCTGGCCTTGCTCAGAAGTTTTGTTGCCGTCTCTTC
  TTAGCCTCTATGGCATCCAGGATGGGCTGCCGCTTGGACTGGTACTTCTGCCGGATCTCT
  TCAATCTCCTGCTCCATCATGGGGTCCAGGGCCAAGAGCCTCTTCTGAAGGTCCTCCACT
  GTCCAACTCTTAAGAAACTCGTAGTCTCCCATCCTGTGGTATTTTCCAATCTGAAGAATT
  TTTCAGTGGACCAGGTACACTCTTGCCAAAGCCTGTTGATCTGGTTTTCCTTTTTCTTTT
  TGTTCAAATATTCAAGAAAGATGGTTTCGCCAGCTGCATGGTCTCATCCCTTCTTTTCAT
  AAGTCCTTTCTCTTCCTCATTCTCTGCGATTGACACCAATGTGCCCAATTGTGATGGGAA
  CGTGTCATCGTGCTCCAACATTATCATTGCCTCCATCAATCATGGTGCTGGGTACTGGGA
  CGTGGCCATTTTATTACCCCTGGTTGACCATGGGCCAAAATCATGTCTTCTTTTCCTGAA
  AAGGAACAATT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006282
• Insert Size: 2600 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_006282.2, NP_006273.1
• RefSeq Size: 6344 bp
• RefSeq ORF: 1464 bp
• Locus ID: 6789
• Cytogenetics: 20q13.12
• Domains: pkinase, TyrKc, S_TKc
• Protein Families: Druggable Genome, Protein Kinase
• Protein Pathways: MAPK signaling pathway, Non-small cell lung cancer, Pathways in cancer
• Gene Summary: 'The protein encoded by this gene is a cytoplasmic kinase that is structurally similar to the yeast Ste20p kinase, which acts upstream of the stress-induced mitogen-activated protein kinase cascade. The encoded protein can phosphorylate myelin basic protein and undergoes autophosphorylation. A caspase-cleaved fragment of the encoded protein has been shown to be capable of phosphorylating histone H2B. The particular phosphorylation catalyzed by this protein has been correlated with apoptosis, and it's possible that this protein induces the chromatin condensation observed in this process. [provided by RefSeq, Jul 2008]'