UBE4B (NM_006048) Human Untagged Clone

CAT#: SC116377

UBE4B (untagged)-Human ubiquitination factor E4B (UBE4B), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: UBE4B
• Synonyms: E4; HDNB1; UBOX3; UFD2; UFD2A
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC116377 sequence for NM_006048 edited (data generated by NextGen Sequencing)
  ATGGAGGAGCTGAGCGCTGATGAGATTCGACGGAGGCGCCTTGCACGACTTGCTGGTGGA
  CAGACCTCTCAGCCAACCACCCCACTCACCTCTCCCCAGAGGGAGAACCCTCCGGGGCCT
  CCCATAGCGGCATCAGCCCCAGGACCCTCTCAGAGTCTTGGTCTCAATGTCCACAACATG
  ACCCCAGCTACCTCCCCAATAGGTGCATCAGGAGTAGCCCATCGAAGCCAGAGCAGTGAA
  GGAGTCAGTTCTCTCAGCAGCTCGCCCTCTAATAGCCTTGAAACGCAATCTCAGTCTCTC
  TCACGTTCCCAGAGCATGGATATCGATGGTGTCTCATGTGAGAAAAGCATGTCCCAGGTG
  GATGTGGATTCAGGAATTGAAAACATGGAGGTTGATGAAAATGATCGAAGAGAAAAGCGG
  AGCCTCAGTGATAAGGAGCCTTCCTCGGGCCCTGAAGTGTCTGAAGAGCAGGCCTTACAG
  CTGGTCTGTAAGATCTTCCGTGTCTCTTGGAAGGACCGGGACAGAGATGTCATCTTTCTT
  TCTTCTCTTTCTGCACAGTTTAAGCAGAACCCAAAAGAAGTATTCTCCGATTTTAAGGAC
  TTGATTGGCCAGATTTTAATGGAAGTGCTAATGATGTCCACTCAGACCAGAGATGAAAAC
  CCATTTGCCAGTCTGACAGCCACATCACAGCCAATTGCTGCAGCAGCACGGTCACCAGAC
  AGAAATCTCTTGCTAAACACTGGCTCCAATCCAGGAACAAGCCCCATGTTCTGCAGCGTG
  GCTTCCTTTGGTGCCAGCTCTTTGTCTAGTTTGGGAGCCTCTGGTGGAGCAAGTAATTGG
  GATTCCTACAGTGACCATTTCACCATTGAAACCTGCAAAGAGACAGATATGCTGAACTAC
  CTCATCGAGTGTTTCGACCGAGTTGGAATAGAGGAAAAAAAAGCACCAAAGATGTGCAGC
  CAGCCAGCAGTCAGCCAGCTTCTGAGCAACATCCGCTCACAGTGCATATCCCATACTGCT
  TTAGTACTACAAGGCTCCCTAACACAGCCCAGGTCCTTGCAGCAGCCGTCCTTCCTAGTG
  CCGTATATGCTGTGTAGGAATCTCCCATATGGCTTCATTCAGGAACTGGTGAGAACCACT
  CACCAGGATGAAGAAGTGTTCAAGCAGATATTTATCCCCATTTTACAAGGCCTGGCTCTT
  GCTGCCAAAGAGTGCTCCCTCGACAGTGACTACTTTAAATACCCCCTCATGGCACTAGGT
  GAGCTCTGTGAAACCAAGTTTGGGAAGACACACCCTGTGTGCAATTTGGTTGCTTCTTTG
  CGGTTGTGGTTGCCGAAATCCTTAAGTCCTGGCTGTGGGCGGGAGCTGCAGAGACTCTCT
  TACTTAGGGGCTTTCTTTAGCTTCTCAGTCTTTGCAGAAGATGATGTTAAAGTGGTTGAA
  AAATACTTCTCAGGGCCTGCCATTACCCTGGAAAACACTCGTGTGGTTAGCCAATCATTG
  CAGCATTACTTAGAGCTCGGAAGGCAAGAGCTTTTTAAGATTCTGCATAGTATTTTGTTA
  AATGGCGAAACCCGTGAGGCTGCTCTCAGTTACATGGCGGCTGTCGTCAATGCCAATATG
  AAGAAAGCACAGATGCAGACAGATGATAGATTGGTGTCTACAGATGGATTTATGCTGAAT
  TTCCTTTGGGTACTGCAGCAGCTAAGTACAAAAATCAAGTTAGAAACAGTTGATCCCACG
  TATATTTTTCACCCAAGATGTCGGATTACTCTTCCCAATGATGAGACGCGTGTGAATGCA
  ACGATGGAAGATGTGAATGACTGGCTGACTGAACTCTATGGCGATCAGCCTCCATTTTCT
  GAGCCGAAATTCCCTACGGAGTGCTTCTTTCTCACCCTGCATGCTCACCACCTCTCTATT
  CTGCCTAGTTGCCGTCGCTATATCCGCAGACTCCGGGCTATCCGGGAGCTCAATAGAACT
  GTAGAAGATTTGAAAAATAATGAAAGCCAATGGAAAGATTCCCCACTGGCAACTAGACAC
  CGCGAAATGCTGAAGCGCTGTAAAACTCAGCTTAAGAAACTGGTACGGTGCAAGGCCTGT
  GCTGATGCTGGCCTACTTGACGAGAGCTTCCTGAGAAGATGTCTGAATTTTTATGGCCTT
  CTCATTCAGCTGCTGCTCCGCATCCTGGACCCCGCATATCCCGATATAACACTGCCTTTA
  AATTCAGATGTCCCCAAGGTATTTGCAGCGTTGCCTGAGTTTTATGTAGAAGATGTTGCA
  GAATTTTTATTTTTTATTGTACAATACTCTCCCCAGGCGCTTTATGAGCCCTGTACTCAG
  GATATTGTGATGTTCCTTGTTGTGATGTTGTGCAACCAGAACTACATCCGAAACCCATAT
  TTGGTGGCCAAACTGGTAGAAGTCATGTTTATGACCAACCCTGCTGTTCAGCCACGAACC
  CAGAAGTTTTTTGAAATGATTGAGAACCATCCTCTCTCCACCAAGTTGTTGGTACCTTCC
  CTGATGAAGTTTTATACAGATGTTGAGCATACCGGAGCCACCAGTGAGTTTTATGACAAG
  TTCACAATTCGCTATCATATTAGCACCATTTTTAAAAGCCTTTGGCAAAACATAGCTCAC
  CATGGCACCTTTATGGAGGAGTTCAACTCCGGGAAGCAGTTTGTTCGCTATATAAACATG
  TTGATAAACGACACGACGTTTTTGCTCGATGAAAGTCTGGAGTCTCTGAAGCGAATCCAT
  GAAGTGCAGGAAGAGATGAAGAACAAAGAACAGTGGGACCAGTTGCCCCGGGATCAGCAG
  CAGGCTCGTCAGTCTCAGCTTGCTCAGGATGAGCGTGTGTCCCGCTCTTACCTCGCCCTG
  GCCACCGAAACCGTGGACATGTTCCACATCCTCACGAAGCAGGTCCAGAAGCCCTTCCTC
  AGACCGGAGCTTGGACCCCGATTGGCTGCAATGCTGAACTTTAATCTTCAGCAACTTTGT
  GGCCCCAAGTGCCGTGACCTGAAAGTTGAAAACCCTGAGAAATACGGCTTTGAACCAAAG
  AAGCTGTTGGACCAACTGACGGATATTTACTTACAGCTGGACTGTGCTCGGTTCGCGAAA
  GCCATTGCTGACGACCAGAGATCCTACAGTAAGGAATTGTTTGAAGAAGTTATTTCAAAG
  ATGCGGAAGGCAGGGATCAAATCCACAATAGCAATAGAAAAATTTAAGCTGCTCGCCGAG
  AAAGTGGAGGAGATAGTGGCCAAGAACGCACGCGCAGAAATCGACTACAGCGACGCTCCT
  GATGAGTTCAGAGACCCTCTGATGGACACCCTCATGACAGACCCCGTGCGGCTGCCCTCT
  GGCACCATCATGGACCGCTCCATCATCCTGCGGCACCTGCTCAACTCCCCCACGGACCCC
  TTCAACCGGCAGACGCTGACAGAGAGCATGCTGGAACCAGTGCCAGAACTGAAAGAGCAG
  ATTCAGGCGTGGATGAGAGAGAAACAGAACAGCGATCACTAA
  
  Clone variation with respect to NM_006048.4
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_006048 unedited
  CGGATTTTGTAATACGACTCACTATTAGGGCGGCCGCGATTCGGCACCAGGCAGGATCTG
  CTGTAGGAACGCAGCTACCGCGCCACTATCACGAAGAACAGCAGGCTCGGGGCACGAGAC
  GAACTGGAGACCGCGCTGCCTAGCTGGGTAACCTGGGAAGCAGAGGGTAATAAGTGGCGC
  CTTAAGACAACCCTGTAGCAGCAGCAGTGGCGGCCAAAGGAGGCTGCTCAGGGAACAAGC
  GGCTGTAGTAGTCTGTGGGGCGACTGGAGTGACCGAAGCCAAGGCAGTTTAGTGCCTCTC
  GTGTTCTTATTTTTTAACCTCTGACTATGCAATTCTGAAACCTCCCCCATTCGGGGGACC
  AGACAGCCTGATAGACACCTTCCACTCTCCTTCCTCCCGCCGTGGTCTCGAGAACAGAAG
  GATCTCTCCTTAACGCCTTTCACCATTAAGAGGAAAGCGATGGAGGAGCTGAGCGCTGAT
  GAGATTCGACGGAGGCGCCTTGCACGACTTGCTGGTGGACAGACCTCTCAGCCAACCACC
  CCACTCACCTCTCCCCAGAGGGAGAACCCTCCGGGGCCTCCCATAGCGGCATCAGCCCCA
  GGACCCTCTCAGAGTCTTGGTCTCAATGTCCACAACATGACCCCAGCTACCTCCCCAATA
  GGTGCATCAGGAGTAGCCCATCGAAGCCAGAGCAGTGAAGGAGTCAGTTCTCTCAGCAGC
  TCGCCCTCTAATAGCCTTTGAACGCAATCTCAGTCTCTCTCACGTTCCCAGAGCATGGAT
  ATCGATGGTGTCTCATGTGAGAAAAGCATGTCCCAGGTGGATGTGGATTCAGGAATTGAA
  ACATGGNAGGTGATGAAAATGATCGAAGAGAAAGCGGAGCCTCAGTGTAAGGAGCCTTCC
  TCCGGCCCTGAGTGTCTGAAGAGCAGCCCTACAGCTGTCTGGAAGACTTCCTGTCTCTA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_006048 unedited
  ATACTCTGGACCGGCGGCCGCATNCTAGNGTCGAGTTTTTTTTTTTTTTTTTTTTTCTGA
  AAAATCTTGCCTTTTTTATTAATCATGTCATCTAACACCAATTAAAAAAACAATATGTGA
  ATATGATATAAAAATACGATCCCAGGATTAACACTTGGTAGCAGGCACAGTTATCTCACA
  GAATATATGTTTGGAGGGCCAGGGAAAGGAGTTTACTTTTGTTTTTGCTTCTCTTAAAAA
  AATCCACAGCAGTGCAAGTAGGGTCAGGAAGGGGGAGAGGGGAAAAAAGATTCTTTAGCA
  GCAAAATGTCCAAGGTTCTCTAATCACAATCAAATCAACGGATATTGGATTAAAAAAAAA
  TTCATGAAGGGATGCTGCCCAGACCCATTAGCCATCACTAAAAGACTTCCGTTGCCCCAA
  ACTGTGACATACGAAGGACATGCTTTATTACACAAGCAACCATAAAACCTGTCCCTTAAG
  CTTTTGACCGTGTTTGTCACTTAAATATATGTACAGGAAGCGGGCTCCTCTTCTCATCCA
  TGTCCTTTCAGGTCTCAGCGTTTGCTCGCTCTGGGTGGGCCTGGGGTTGGTTTGCCACAT
  TTGGCCTCCACACATGAACGGCAGCTTCGCTGCGGCCGCTGCTTCTGCTTGCCTCGTTGG
  CCTTGGCTGTGTCTAGCAGAGGGTGGGCGGCGGAACGGTTTANNGATCGCTGNTCTGTTT
  CTCTCTCATCCACGCCTGAATCTGCTCTTTCAGTTCTGGCACTGGTTCCAGCATGCTCTC
  TGTCANCGTCTGCCGTTGAAGGGGTCCGTGGGGGATTGANCCAGTGCCGCAAGATGATGA
  ACGTCCATGATGGTGCAAAGGGCANCCGAACGGGTCTGCATGAAGGTGTCATCAAAGGTC
  CTTGACTCATCAGAGCGCCCTGTATCCATTCTGGCGCGGCGTTTTGCACCTATTTCCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_006048
• ORF Size: 3522 bp
• Insert Size: 4600
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_006048.2, NP_006039.2
• RefSeq Size: 5512
• RefSeq ORF: 3522
• Locus ID: 10277
• Domains: U-box
• Protein Pathways: Ubiquitin mediated proteolysis
• Gene Summary: The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes an additional conjugation factor, E4, which is involved in multiubiquitin chain assembly. This gene is also the strongest candidate in the neuroblastoma tumor suppressor genes. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) lacks an in-frame coding exon in the middle region of the CDS, and thus encodes a shorter isoform (2), as compared to variant 1.