ALDH6A1 (NM_005589) Human Untagged Clone

CAT#: SC116671

ALDH6A1 (untagged)-Human aldehyde dehydrogenase 6 family, member A1 (ALDH6A1), nuclear gene encoding mitochondrial protein


  "NM_005589" in other vectors (7)

Reconstitution Protocol

USD 760.00

2 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ALDH6A1
Synonyms MMSADHA; MMSDH
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_005589, the custom clone sequence may differ by one or more nucleotides


ATGGCGGCGCTATTGGCGGCGGCGGCAGTGCGAGCCCGGATCCTGCAGGTTTCTTCCAAGGTGAAATCCA
GTCCCACCTGGTATTCAGCATCTTCCTTCTCTTCTTCAGTGCCAACTGTAAAGCTCTTCATTGGTGGGAA
ATTCGTTGAATCCAAAAGTGACAAATGGATCGATATCCACAACCCAGCCACCAATGAGGTCATTGGTCGG
GTCCCTCAGGCCACCAAGGCAGAAATGGATGCAGCCATTGCTTCCTGCAAACGTGCTTTTCCTGCATGGG
CAGACACTTCAGTATTAAGCCGCCAGCAGGTCTTGCTCCGCTATCAACAACTTATTAAAGAAAACTTGAA
AGAAATTGCCAAGTTAATCACATTGGAACAAGGGAAGACCCTAGCTGATGCTGAAGGAGATGTATTTCGA
GGCCTTCAGGTGGTTGAGCATGCCTGTAGTGTGACATCCCTCATGATGGGAGAGACCATGCCATCCATCA
CCAAAGACATGGACCTTTATTCCTACCGTCTGCCTCTGGGAGTGTGTGCAGGCATTGCTCCATTCAATTT
TCCTGCCATGATCCCCCTTTGGATGTTTCCCATGGCCATGGTGTGTGGAAATACCTTCCTAATGAAACCA
TCTGAGCGAGTCCCTGGAGCAACTATGCTTCTTGCTAAGTTGCTCCAGGATTCTGGTGCCCCTGATGGAA
CATTAAACATCATCCATGGACAGCATGAAGCTGTAAATTTTATTTGCGATCATCCGGACATCAAAGCAAT
CAGCTTTGTGGGATCCAACAAGGCAGGAGAGTATATCTTCGAGAGAGGATCAAGACATGGCAAGAGGGTT
CAAGCCAATATGGGAGCCAAGAACCATGGGGTAGTCATGCCAGATGCCAATAAGGAAAATACCCTGAACC
AGCTGGTTGGGGCAGCATTTGGAGCTGCTGGTCAGCGCTGCATGGCTCTTTCAACAGCAGTCCTTGTGGG
AGAAGCCAAGAAGTGGCTGCCAGAGCTGGTGGAGCATGCCAAAAACCTGAGAGTCAATGCAGGAGATCAG
CCTGGAGCTGATCTTGGCCCTCTGATCACTCCCCAGGCCAAAGAGCGAGTCTGTAATCTGATTGATAGTG
GAACAAAGGAGGGAGCTTCCATCCTTCTTGATGGACGAAAAATTAAAGTGAAAGGCTATGAAAATGGCAA
CTTTGTTGGACCAACCATCATCTCGAATGTCAAGCCAAATATGACCTGTTACAAAGAGGAGATTTTTGGT
CCAGTTCTTGTGGTTCTGGAGACAGAAACATTGGATGAAGCCATCCAGATTGTAAATAACAACCCATATG
GAAATGGAACTGCCATCTTCACCACCAATGGAGCCACTGCTCGGAAATATGCCCACTTGGTGGATGTTGG
ACAGGTGGGAGTGAATGTCCCCATTCCAGTGCCTTTGCCAATGTTCTCATTCACCGGCTCTCGATCCTCC
TTCAGGGGAGACACCAATTTCTATGGCAAACAGGGCATCCAATTCTACACTCAGTTAAAGACCATTACTT
CTCAGTGGAAAGAAGAAGATGCTACTCTTTCCTCACCTGCTGTTGTCATGCCTACCATGGGCCGTTAG


>OriGene 5' read for NM_005589 unedited
AGGATTTTGTAATACGACTCACTATAGGGCGGCCGCGACTTCGGCACGAGGCCTCGTGCC
GAATTCGGCACGAGGCTAGGGCGGCCGAGAGCCATGGCGGCGCTATTGGCGGCGGCGGCA
GTGCGAGCCCGGATCCTGCAGGTTTCTTCCAAGGTGAAATCCAGTCCCACCTGGTATTCA
GCATCTTCCTTCTCTTCTTCAGTGCCAACTGTAAAGCTCTTCATTGGTGGGAAATTCGTT
GAATCCAAAAGTGACAAATGGATCGATATCCACAACCCAGCCACCAATGAGGTCATTGGT
CGGGTCCCTCAGGCCACCAAGGCAGAAATGGATGCAGCCATTGCTTCCTGCAAACGTGCT
TTTCCTGCATGGGCAGACACTTCAGTATTAAGCCGCCAGCAGGTCTTGCTCCGCTATCAA
CAACTTATTAAAGAAAACTTGAAAGAAATTGCCAAGTTAATCACATTGGAACAAGGGAAG
ACCCTAGCTGATGCTGAAGGAGATGTATTTCGAGGCCTTCAGGTGGTTGAGCATGCCTGT
AGTGTGACATCCCTCATGATGGGAGAGACCATGCCATCCATCACCAAAGACATGGACCTT
TATTCCTACCGTCTGCCTCTGGGAGTGTGTGCAGGCATTGCTCCATTCAATTTTCCTGCC
ATGATCCCCCTTTGGATGTTTCCCATGGCCATGGTGTGTGGAAATACCTTCCTAATGAAA
CCATCTGAGCGAGTCCCTGGAGCAACTATGCTTCTTGCTAAGTTGCTCCACGATTCTGGT
GCCCCTGATGGAACATTANACATCATCCATGGACAGCATGAAGCTGTAAATTTTATTTTG
CGATCATCCGGACATCAAAGCAATCAGCTTTGTTGGGATCCAACAGGCAGGAGAGTATAT
CTTCGACAGAGATCAAGACATGCAGGAGGGTCAAGCCATATGGGAGCCAGACCATGGGGT
AA
>OriGene 3' read for NM_005589 unedited
CGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTCTCTTTAAAAGTTTTTAATTT
ATAATTTGTTATTCATAATTAGTACAATGTAGAATCTGAGAAATTTCAAATGAAGCCACA
TTAGAACAAAAAGAAAATACTGACTTTTTAGCCGCGATCACATGAATATAACTGATGAGT
TTTTTTCATCTAAGAAATAAGAAACTCTGAGCAGCAAATAGTTGGCCAGATGAGTTGTTT
CTAATTAGAGCATCACAGTTCTGATTAGTGTGTTTTTTTAGAAGTGATTTCCCTTAAATA
TAAGGAAAATGTTAGGAATCTCTGTGACTACATTTAATTCCACTTGGAATATAGACAATA
ATGACCTTTTATTTAACCCAGCCTATAGTTGTTGGATTGGATTAAATATCACTACCAGGG
CCAGGTGCGGTGGTTCATTTTCTTTACATACACTGGCTTTTCTCCCCTTCAAATCATCAG
AAAATGGGATAATTTTTAGAAATCAGGTTTAAGCACTACTTTCAGATAAGCATTTCATAG
TTACAACAGTTACCTCAAAATAGAAGTATGAAGAGCAAGTGAGAAATCTGGTTTCATTGT
TACACTAGGCAGTTCCCTATAGAAACTTTGCAGGGGTTAATAGTCCTGNAGAAGATTTTA
GTTACAATGTATTCCAATCCCATCGATCTGATCTGAGCAAAGCTGACAAATGAAGCTGGT
CAAAAATAAGGGAGATTACTCAGGATGGAGTCAGTCTTAAACAACCTTGTTCTAACGGCC
ATGGTAGGCATGACAACAGCAGGTGAGGGAAGAGTAGCATCTTCTTCTTNCACTGAGAAG
TAATGGTCTTCACTGAGTTANAATTGGAGCCCTGTTTGCCTANAAATGTGTCTCCCTGAA
GAGATCGGAGCCGTGATGAAAACTTGCAAGGCCTGGATGGGACATTACTCACTGTCACAT
CCCAGGGG
Restriction Sites NotI-NotI     
ACCN NM_005589
Insert Size 2500 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_005589.2, NP_005580.1
RefSeq Size 2183 bp
RefSeq ORF 1608 bp
Locus ID 4329
Cytogenetics 14q24.3
Domains aldedh
Protein Families Druggable Genome, Transmembrane
Protein Pathways Inositol phosphate metabolism, Metabolic pathways, Propanoate metabolism, Valine, leucine and isoleucine degradation
Gene Summary 'This gene encodes a member of the aldehyde dehydrogenase protein family. The encoded protein is a mitochondrial methylmalonate semialdehyde dehydrogenase that plays a role in the valine and pyrimidine catabolic pathways. This protein catalyzes the irreversible oxidative decarboxylation of malonate and methylmalonate semialdehydes to acetyl- and propionyl-CoA. Methylmalonate semialdehyde dehydrogenase deficiency is characterized by elevated beta-alanine, 3-hydroxypropionic acid, and both isomers of 3-amino and 3-hydroxyisobutyric acids in urine organic acids. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]'
Transcript Variant: This variant (1) encodes the longest isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.