MTA2 (NM_004739) Human Untagged Clone

CAT#: SC117188

MTA2 (untagged)-Human metastasis associated 1 family, member 2 (MTA2)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MTA2
• Synonyms: MTA1L1; PID
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_004739, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGGCGGCCAACATGTACCGGGTGGGAGATTACGTCTATTTTGAGAACTCTTCCAGCAATCCTTACCTGG
  TTAGACGGATTGAGGAGCTCAACAAGACTGCAAATGGAAATGTGGAGGCAAAGGTTGTCTGTCTTTTCCG
  GCGCAGGGACATTTCTAGTAGCCTCAACAGCCTGGCTGATAGTAATGCCAGGGAGTTTGAAGAGGAATCA
  AAGCAGCCAGGGGTGTCTGAGCAGCAGCGCCATCAACTGAAGCACCGGGAACTTTTTCTTTCTCGGCAAT
  TTGAATCATTACCAGCCACCCACATACGGGGGAAATGCAGTGTGACCCTCTTGAATGAGACAGATATCTT
  GAGCCAGTACCTGGAAAAGGAGGACTGCTTTTTTTACTCACTGGTGTTTGACCCCGTGCAGAAGACACTT
  CTCGCTGATCAGGGCGAGATTAGAGTTGGTTGCAAATACCAAGCTGAGATCCCAGATCGCCTAGTAGAGG
  GAGAATCTGATAATCGGAACCAGCAGAAGATGGAGATGAAGGTCTGGGACCCAGACAACCCTCTCACAGA
  CCGGCAGATCGACCAGTTTCTTGTGGTGGCCCGAGCTGTGGGAACCTTTGCAAGAGCCCTAGATTGTAGC
  AGCTCCATTCGGCAGCCAAGCTTGCACATGAGTGCAGCTGCTGCCTCCCGAGATATCACTCTGTTTCACG
  CCATGGATACCTTGCAAAGGAACGGCTACGACCTGGCTAAGGCCATGTCGACCCTGGTACCCCAGGGAGG
  CCCGGTGCTGTGTCGGGATGAGATGGAGGAATGGTCAGCCTCAGAGGCCATGCTATTTGAGGAGGCCCTA
  GAGAAGTATGGGAAGGACTTCAATGATATTCGCCAGGATTTTCTACCCTGGAAGTCACTTGCCAGCATAG
  TCCAGTTTTATTACATGTGGAAAACCACAGACCGGTATATTCAGCAGAAAAGGTTGAAAGCTGCTGAAGC
  AGACAGCAAACTGAAACAGGTCTACATTCCCACCTACACTAAGCCAAACCCTAACCAGATCATTTCTGTG
  GGTTCAAAACCTGGCATGAATGGGGCTGGATTTCAGAAGGGCCTGACTTGTGAGAGTTGCCACACCACAC
  AGTCTGCTCAGTGGTATGCCTGGGGCCCACCTAACATGCAGTGCCGCCTCTGTGCTTCCTGTTGGATCTA
  CTGGAAGAAGTATGGGGGACTGAAGACCCCAACTCAGCTTGAGGGGGCCACTCGGGGCACCACGGAGCCA
  CACTCAAGGGGTCATTTATCCAGACCTGAAGCTCAAAGTCTCTCTCCTTACACAACCAGCGCCAACAGGG
  CCAAGCTACTGGCTAAGAACAGACAAACTTTCCTGCTTCAGACCACAAAGCTGACCCGTCTTGCCAGACG
  CATGTGCAGGGACCTATTACAGCCAAGGAGGGCCGCCCGACGGCCTTATGCTCCTATCAATGCCAATGCC
  ATCAAAGCAGAGTGCTCCATTCGACTTCCTAAGGCCGCCAAGACTCCATTGAAGATTCACCCTCTGGTGC
  GGCTGCCCCTGGCAACTATCGTCAAAGATCTGGTGGCCCAGGCACCCCTGAAACCAAAAACACCTCGGGG
  TACCAAGACACCGATCAACAGAAACCAGCTGTCCCAGAACCGGGGACTGGGGGGCATTATGGTGAAACGG
  GCCTATGAGACTATGGCAGGGGCAGGGGTTCCTTTCTCTGCCAATGGAAGGCCTCTGGCTTCAGGGATTC
  GTTCAAGCTCACAGCCAGCAGCCAAGCGTCAGAAACTAAACCCAGCTGATGCCCCCAATCCTGTGGTGTT
  TGTGGCCACAAAGGATACCAGGGCCCTACGGAAGGCTCTGACCCATCTGGAAATGCGGCGAGCTGCTCGC
  CGACCCAACTTGCCCCTGAAGGTGAAGCCAACGCTGATTGCAGTGCGGCCCCCTGTCCCTCTACCTGCAC
  CCTCACATCCTGCCAGCACCAATGAGCCTATTGTCCTGGAGGACTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004739 unedited
  GGATTTGTATACGACNACTATAGGCGGCCGCGACTTCGGCATAGCGAACCCTGAGGCGGG
  CCCGGCAAGCCTTCCCTGCGGCCGGCAGAGCCCAACGACTAGTGGGACTCCGCGGGGGCG
  GGGGTAGCTGGAGCCTGGCTCTGGCCTGGCAGGAGCCGAGCTCGTTCCGGAAGAAGCCGA
  GCGGACGGGGGCCAGCCTCAGCGTCCCGGGAGTGAGGCGATAGCTGCGGCGGCGACAGCG
  CGGGCCGGGATGAACCGCGACGGCTGATGCAGCGGAGGTGCCGGCTGCGCGGGCCCCAGT
  GAGACTCCCTCGAAGCGGCAGCCCACCGTTCGGGGCTTTGCCTCGAGCCGAGCCCTGCCC
  CCGCGAGCCTCCCGGACCCCTTTGTGCGGCCGGAGGCGGCGGCGGGAACGGCCATGGCGG
  CCAACATGTACCGGGTGGGAGATTACGTCTATTTTGAGAACTCTTCCAGCAATCCTTACC
  TGGTTAGACGGATTGAGGAGCTCAACAAGACTGCAAATGGAAATGTGGAGGCAAAGGTTG
  TCTGTCTTTTCCGGCGCATGGACATTTCTAGTAGCCTCAACAGCCTGGCTGATAGTAATG
  CCAGGGAGTTTGAAGAGGAATCAAAGCAGCCAGAGGTGTCTGATCAGCAGCGCCATCAAC
  TGAAGCACCGGGAACTNTTTCTTTCTCGGCATTTGAATCATTACCAGCCACCCACATACG
  GGGGAAATGCAGTGTGACCCTCTTGATGAGACAGATATCTTGAGCCAGTACCTGGNAAAG
  GGAGACTGCTNTTTTACTCACTGGTGTTTGACCCCGTGCAGAAAACACTTCTCGCTGATC
  AGGGGCGAGATANNAGTGGGTTGCAATACCCAGCTGAGATCCCAGATCGCCTAGTAGAGG
  GAGATCTGATATTCGGACCCCATATATGAGATGATGTCTGGGACCAGACACCTCTACAGA
  CGGCAGACGACATTTNCTGTGGTGCCCGACTGTGGAACCTGCAGANCCTNATGTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004739 unedited
  AGCACGTGGGGAAGGGGTACACAGGGCATGCCACCCGGGATCTGTTCAGGAAACAGCTAT
  GACCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAAAAAAACGGACAA
  AAGATCTTTATTTCTGAGAACTGGCGTACAAAAGGCAGAGGGGGAGGGGAGGGAAGGAAA
  GAGCGAGCGTGGCCTGGGGTTGATGCCAGCTTAGGGGCCTCAAACTCCAATTAGGAAAGT
  CCGGACACCGGACAGAAAGAGAAACCCCCAATTAGGAAAAAAAAAAAAAAAAAAAAAAAA
  AAGACATGGCAGTGCACGCCCCCCTCCCCCAACCAGGTACCACCACCTGTTATCTGTTTA
  CTCTTCCCCTCCCCATCCCCTTTCACAAAGGGAGGCAAAACTTTTAAAAAATTAAAAAAC
  CCTCCCCCCAAAACTGTCCAAGACATCTGTGGGTCCTACCCCCCAAAACAGGCTAGGTTC
  CCACATGGGCCAAGTTCCTGCAGTCTGTCCTCCATCGGCAAGCATGGAGGCATGAGACAA
  GTCTCGAGGTGGTAACACCAGAGGGCGCCCAACCCCTCCAGGGACACACACTCACTTGCT
  CTCTTCCTTAATTCACTCCTCACTCCCTTCGACACGAAAGGGAAGGGAGGTTTTGGGTGC
  CCTGGGCATCCACCCTCTACCTCTCAGCCCACCTCCCTTCCCCACAGGTGCTCAGTCCTC
  CAGGACAATAGGCTCATTGGTGCTGGCAGGATGTGAGGGTGCAGGTAAAGGGACAGGGGG
  CCCGCCCTGCAATCAGCGTTGGCTTCACCTTCGGGGCAAGTTGGTTCGCGAACCACCCGC
  CCCATTTCCAATGGGTCAAAACCCTTCGTAGGGCCCCGGTACCTTTGGGA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004739
• ORF Size: 2007 bp
• Insert Size: 3000
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_004739.2, NP_004730.2
• RefSeq Size: 3060
• RefSeq ORF: 2007
• Locus ID: 9219
• Domains: GATA, ELM2, myb_DNA-binding, BAH
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq, May 2011]