Apg12 (ATG12) (NM_004707) Human Untagged Clone

CAT#: SC117215

ATG12 (untagged)-Human ATG12 autophagy related 12 homolog (S. cerevisiae) (ATG12), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: ATG12
• Synonyms: APG12; APG12L; FBR93; HAPG12
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_004707 edited
  GAATTCGGCACGAGGGTAGTCGCGGAGAAACACATGTTGCGTTACTAACGTTCAGAGGTC
  TGCGACAGCTTCGATTTGAATGACTAGCCGGGAACACCAAGTTTCACTGTGTAATTGCGT
  CCCCCTACTCCGGCGCCTCCTTTGCGACGCTCCCTGGAGAAAAGCACGCCCACTGCACGC
  GCTCAGTCGCTACTTCCGCTCTCGAGTGTCTCCAAGCAAGATGGCGGAGGAGCCGCAGTC
  TGTGTTGCAGCTTCCTACTTCAATTGCTGCTGGAGGGGAAGGACTTACGGATGTCTCCCC
  AGAAACAACCACCCCGGAGCCCCCGTCTTCCGCTGCAGTTTCCCCGGGAACAGAGGAACC
  TGCTGGCGACACCAAGAAAAAAATTGACATTTTGCTAAAGGCTGTGGGAGACACTCCTAT
  TATGAAAACAAAGAAGTGGGCAGTAGAGCGAACACGAACCATCCAAGGACTCATTGACTT
  CATCAAAAAGTTTCTTAAACTTGTGGCCTCAGAACAGTTGTTTATTTATGTGAATCAGTC
  CTTTGCTCCTTCCCCAGACCAAGAAGTTGGAACTCTCTATGAGTGTTTTGGCAGTGATGG
  TAAACTGGTTTTACATTACTGCAAGTCTCAGGCGTGGGGATGAACCACAAAGAAAATCAA
  CTTGCTACTACATGAAATGGATTTTCACGGAAGAGACAGCTCTGAAAAGTTTTGATGCTT
  GTGGCAAGAGACTTAACAGATGTGATCTATTTAGTATGTGTCTACTCTGTGTTTATGCAT
  AAGAAAACATCCATAGCATGAATGGACTCAGAAAAATGTGATTTGTATTAATGCACCAGT
  CATCATAAAAGATGGTCATGATAGTACACCCATTGCTCCTACTTGTTACTATTATTGCTG
  CAGATCTGCCTCCAAGGTTGAAAAGGAGACTAAGACTGTATAAACATCTTCATTGTCAGT
  TCTCAAAATGACTGAAATTGTTTTCXXXXXXXXXXXXXXCTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_004707 unedited
  NAGGTCAGTATTTGTATACGACTCATATAGGGCGGCCGCGAATCGGCACGAGGGTAGTCG
  CGGAGAAACACTGTTGCGTTACTAACGTTCAGAGGTCTGCGACAGCTTCGATTTGAATGA
  CTAGCCGGGAACACCAAGTTTCACTGTGTAATTGCGTCCCCCTACTCCGGCGCCTCCTTT
  GCGACGCTCCCTGGAGAAAAGCACGCCCACTGCACGCGCTCAGTCGCTACTTCCGCTCTC
  GAGTGTCTCCAAGCAAGATGGCGGAGGAGCCGCAGTCTGTGTTGCAGCTTCCTACTTCAA
  TTGCTGCTGGAGGGGAAGGACTTACGGATGTCTCCCCAGAAACAACCACCCCGGAGCCCC
  CGTCTTCCGCTGCAGTTTCCCCGGGAACAGAGGAACCTGCTGGCGACACCAAGAAAAAAA
  TTGACATTTTGCTAAAGGCTGTGGGAGACACTCCTATTATGAAAACAAAGAAGTGGGCAG
  TAGAGCGAACACGAACCATCCAAGGACTCATTGACTTCATCAAAAAGTTTCTTAAACTTG
  TGGCCTCAGAACAGTTGTTTATTTATGTGAATCAGTCCTTTGCTCCTTCCCCAGACCAAG
  AAGTTGGAACTCTCTATGAGTGTTTTGGCAGTGATGGTAAACTGGTTTTACATTACTGCA
  AGTCTCAGGCGTGGGGATGAACCACAAAGAANATCAACTTGCTACTACATGAAATGGATT
  TTCACGGAAGAGACAGCTCTGAAAAGTTTTGATGCTTGTGGCAAGAGACTTAACAGATGT
  GATCTATTTAGTATGTGTCTACTCTGTGTTTATGCATAAGAAACATCCCTAGCATGAATG
  GACTCAGAAAATGTGATTTGATTAATGCACCAGTCATCATAAAGATGTCATGATAGTACA
  C
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_004707 unedited
  TCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTAAAATTCAACATATTTT
  TATTTGTTAAATATATGAATATAATTAAATATATTCCTTCAGTAAACTGAACTGGACAAA
  ACTAGAGAACAGACCTTTTCCATACTCATTTAACTTTAAAATGATATTACTTTGAATTCT
  ACTACATACCATCTTAGATCCTGTTTTGAAATTCCATTCACATTACATTCGATTTACTAG
  AATGCCTTTTTTTTTCTTTTTTGAGATGGGGTCTCACTCTGTTGCTCAGCAGGAATGCAG
  TGGTACAATCACGACTCACTATACCCTTGAACTTCTGGGCTCAGGGGATCCTCTTGCCTC
  TGCAGCCTAATAATTTTTTTTTAATTTTTATTTTTTTGTAGAGTTGGGGATCTTGCCTTG
  CTAACCAGGCTGGTCTCAAACTTGTGGCTTCACGCAATCCCCACACCTCAGCCTTCCAAA
  GTGCTGGGATTACAGGTGTAAGCCACCATGCCTGATCTGGAATGCTTTCTAAAAATATGG
  CATTATAAACATAATACTAAAGAGAAAAAAAGGTTAAATTTCACTTCAAGAAATTATCAG
  TCTAATAGCATCAGTAAAAATGGCACTTTTAGTCATGGCATAAAATATACAATAAGGCTA
  TTTTTCAATTATTTGTTTTCAAGTTGGGAAAATGCATTATGAAACACTCAAAAGATGCTA
  CTGGGGTTACTCATCAAGGGCTTTTGACACCATATAATGACAGAGTAACACCACAGTTAT
  GTGATGGGGACTCCAGATTCCTTAAATGTTAGGACTGAAACAGGGTTATGACTTATTTGG
  CCAGAATTATATTTTTCTGTACCCCATTACATATTAAGCCTGTGTATTGGGGTAAATAAC
  GTCTTCAGT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_004707
• ORF Size: 564 bp
• Insert Size: 2260
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_004707.2, NP_004698.2
• RefSeq Size: 2359
• RefSeq ORF: 564
• Locus ID: 9140
• Domains: APG12
• Protein Pathways: Regulation of autophagy, RIG-I-like receptor signaling pathway
• Gene Summary: Autophagy is a process of bulk protein degradation in which cytoplasmic components, including organelles, are enclosed in double-membrane structures called autophagosomes and delivered to lysosomes or vacuoles for degradation. ATG12 is the human homolog of a yeast protein involved in autophagy (Mizushima et al., 1998 [PubMed 9852036]). [supplied by OMIM, Mar 2008]
  Transcript Variant: This variant (1) encodes the longer protein (isoform 1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.