Apc6 (CDC16) (NM_003903) Human Untagged Clone

CAT#: SC117672

CDC16 (untagged)-Human cell division cycle 16 homolog (S. cerevisiae) (CDC16), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDC16
• Synonyms: ANAPC6; APC6; CDC16Hs; CUT9
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117672 sequence for NM_003903 edited (data generated by NextGen Sequencing)
  ATGAACCTAGAGCGGCTGCGGAAGCGCGTCCGGCAGTACCTCGACCAGCAACAGTATCAA
  AGTGCTCTATTTTGGGCAGATAAAGTAGCTTCACTCTCTCGTGAAGAACCCCAGGACATC
  TATTGGTTGGCTCAGTGTCTTTACCTGACAGCACAATATCACAGAGCCGCCCATGCACTT
  CGGTCACGAAAACTGGACAAATTGTATGAAGCATGTCGTTACCTTGCAGCTAGGTGCCAT
  TATGCTGCAAAAGAGCACCAGCAGGCCCTTGATGTTCTTGACATGGAAGAGCCCATCAAT
  AAAAGATTATTTGAAAAATACTTGAAGGATGAAAGTGGCTTCAAAGATCCCTCCAGCGAC
  TGGGAAATGTCACAGTCTTCAATAAAGAGTTCTATCTGTCTTCTACGCGGGAAAATCTAT
  GATGCTCTAGATAACCGAACCCTGGCTACCTACAGCTACAAAGAAGCTTTGAAGCTTGAT
  GTCTACTGTTTTGAAGCGTTCGATCTTTTAACATCACATCACATGCTGACAGCACAAGAA
  GAAAAAGAACTTCTTGAATCACTACCCCTTAGCAAGCTGTGTAATGAAGAACAGGAATTG
  CTGCGTTTTCTATTTGAGAACAAATTGAAAAAATATAATAAGCCTAGTGAAACGGTCATC
  CCTGAATCTGTAGATGGCTTGCAAGAGAATCTGGATGTGGTAGTGTCTTTAGCTGAGAGA
  CATTATTATAACTGTGATTTTAAAATGTGCTACAAGCTTACTTCTGTAGTAATGGAGAAA
  GATCCTTTCCATGCAAGTTGTTTACCTGTACATATAGGGACGCTTGTAGAGCTGAATAAA
  GCCAATGAACTTTTCTATCTTTCTCATAAACTGGTGGATTTATATCCTAGTAATCCTGTG
  TCTTGGTTTGCAGTGGGATGTTACTATCTCATGGTCGGTCATAAAAATGAACATGCCAGA
  AGATATCTCAGCAAAGCCACAACACTTGAGAAAACCTATGGACCTGCATGGATAGCCTAT
  GGACATTCATTTGCGGTGGAGAGTGAGCACGACCAAGCGATGGCTGCTTACTTCACAGCA
  GCACAGCTGATGAAAGGGTGTCATTTGCCTATGCTGTATATTGGATTAGAATATGGTTTG
  ACCAATAACTCAAAACTAGCTGAAAGGTTCTTCAGCCAAGCTCTGAGCATTGCACCGGAA
  GACCCTTTTGTTATGCATGAGGTCGGCGTGGTTGCATTTCAGAATGGAGAATGGAAAACA
  GCCGAAAAATGGTTTCTTGATGCTTTGGAAAAAATTAAAGCAATTGGGAACGAGGTAACA
  GTTGACAAATGGGAACCTTTGTTGAACAACTTGGGGCATGTCTGCAGAAAACTTAAAAAG
  TATGCTGAGGCCTTGGATTACCACCGTCAGGCACTGGTGTTGATTCCTCAGAACGCATCC
  ACCTACTCTGCTATTGGATATATCCACAGTCTGATGGGCAACTTTGAAAATGCTGTGGAC
  TACTTCCACACAGCCCTTGGTCTTAGGCGAGATGATACATTTTCTGTTACAATGCTTGGT
  CATTGCATCGAAATGTACATTGGTGATTCTGAAGCTTATATTGGAGCAGACATTAAAGAC
  AAATTAAAATGTTATGACTTTGATGTGCATACAATGAAGACACTAAAAAACATTATTTCA
  CCTCCGTGGGATTTCAGGGAATTTGAAGTAGAAAAACAGACTGCAGAAGAAACGGGGCTT
  ACGCCATTGGAAACCTCAAGGAAAACTCCAGATTCCAGACCTTCCTTGGAAGAAACCTTT
  GAAATTGAAATGAATGAAAGTGACATGATGTTAGAGACATCTATGTCAGACCACAGCACG
  TGA
  
  Clone variation with respect to NM_003903.3
  330 c=>t;351 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003903 unedited
  GATTTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGGACCTGCGGCC
  TTCGAGTCCGCGGCCTTCGAGTCCTGGGGCGGCGGCGGCGGCTGCAGGCACGGGCACGGG
  CACGGGGCGGGGTGCTTAGGGTGCAGGAGGCGCGCGCCTAGCGGCGGAGTGTGGCGTGAG
  GCCGGGCCCGCGCCGCCATGAACCTAGAGCGGCTGCGGAAGCGCGTCCGGCAGTACCTCG
  ACCAGCAACAGTATCAAAGTGCTCTATTTTGGGCAGATAAAGTAGCTTCACTCTCTCGTG
  AAGAACCCCAGGACATCTATTGGTTGGCTCAGTGTCTTTACCTGACAGCACAATATCACA
  GAGCCGCCCATGCACTTCGGTCACGAAAACTGGACAAATTGTATGAAGCATGTCGTTACC
  TTGCAGCTAGGTGCCATTATGCTGCAAAAGAGCACCAGCAGGCCCTTGATGTTCTTGACA
  TGGAAGAGCCCATCAATAAAAGATTATTTGAAAAATACTTGAAGGATGAAAGTGGCTTCA
  AAGATCCCTCCAGCGACTGGGAAATGTCACAGTCTTCAATAAAGAGTTCTATCTGTCTTC
  TACGCGGGAAAATCTATGATGCTCTAGATAACCGAACCCTGGCTACCTACAGCTACAAAG
  AAGCTNTGAAGCTTGATGTCTACTGTTTTGAAAGCGTCGATCTTTTAACATCACATCACA
  TGCTGACAGCACAAGAAGAAAAGAACTTCTTTGATCACTACCCTTNNAGCAGCTGTGTAA
  TGAAGAAACAGAATTGCTGCCGTNTCTATTTGAGAACNNAATGAAAAATATATAAGCCTA
  GTGAAACGGTCATCCTGATCTGTANATGGCTGCAGAGAATCTGGTGC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003903 unedited
  TGAACCGGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTTTTTTTTTTTTTGGAGGGGTACCTTTTTTTTTCCACTTTGTATA
  ACTATTTTGGGGGGTCAAAAAATCAAAACCCATTTGTTGCAAAGGGGGGCCAACCAATCT
  TTTAAGGGGGGTCTTTTTTCCTACCCTGGGACAGGGGGACCCAGACCCCTGGCTGGGGTC
  ACCTGCTGGGGGCTGACATAAATGTCTTTAACATTATGGGACTTTTATTTATTTCAATTT
  CAAAGGGTTTTTCCAAGGAAGGGCTGGAATTTGGAGTTTTCCTTGAGGGTTCCAAAGGGG
  TAAACCCCGTTTTTTTTGCAGGCTGTTTTTTTACTTCAAATTCCCTGAAATCCCACGGGG
  GGGAAAAAATGGTTTTTAGGGGCTTCATTGGGTGCCCCTCAAAGGCATAACATTTTAATT
  TGGCTTTAAAGGCCGCTCCAAAATAAACTTCAAAAACACCAATGTACATTTCGATGCAAT
  GACCAAACATTGTAACCAAAAATGTATTATTTCTCCTAAAACCACAGGGCCTGTGGGGGA
  AGAACTCCACACCCTTTTTAAAAGTGCCCCTCAAACCGGGGGATTTATCCCAAACCACAA
  AAGGGGGGGTCCGTTTTGAGGAATCAACCCCCAGGCCTGGCGGTGGGAATTCCAAGGCCT
  CAAAATTATCTTATAAATTTTTTTGCAAAACTGCCCCACAGTGTTCAACAAGAGTTCCCT
  TTTTGGAAACGTGTAACCCGCTCCCCCATTGGTTTTAATTTTTTCCAAAACATAAAGAAA
  CCTTTTTTGGCTGTGTTTCCATTTCCACTTTCGAAAGCCCCCCCCCCCCCCTCTGCCTAA
  AAAAAGGGGTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003903
• ORF Size: 1860 bp
• Insert Size: 2500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003903.2, NP_003894.2
• RefSeq Size: 2196
• RefSeq ORF: 1860
• Locus ID: 8881
• Domains: TPR
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle, Oocyte meiosis, Progesterone-mediated oocyte maturation, Ubiquitin mediated proteolysis
• Gene Summary: The protein encoded by this gene functions as a protein ubiquitin ligase and is a component of the multiprotein APC complex. The APC complex is a cyclin degradation system that governs exit from mitosis by targeting cell cycle proteins for degredation by the 26S proteasome. Each component protein of the APC complex is highly conserved among eukaryotic organisms. This protein, and other APC complex proteins, contain a tetratricopeptide repeat (TPR) domain; a protein domain that is often involved in protein-protein interactions and the assembly of multiprotein complexes. Multiple alternatively spliced transcript variants, encoding distinct proteins, have been identified. [provided by RefSeq, Jan 2016]
  Transcript Variant: This variant (1) lacks an exon segment in the 3' UTR, compared to variant 2. Variants 1 and 2 encode the same isoform (1).