GALNT4 (NM_003774) Human Untagged Clone

CAT#: SC117755

GALNT4 (untagged)-Human UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 4 (GalNAc-T4) (GALNT4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: GALNT4
• Synonyms: GALNAC-T4; GALNACT4
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117755 sequence for NM_003774 edited (data generated by NextGen Sequencing)
  ATGGCGGTGAGGTGGACTTGGGCAGGCAAGAGCTGCCTGCTGCTGGCGTTTTTAACAGTG
  GCCTATATCTTCGTGGAGCTCTTGGTCTCTACTTTTCATGCCTCCGCAGGAGCCGGCCGT
  GCCAGGGAGCTGGGGTCAAGAAGGCTCTCAGACCTCCAGAAAAATACGGAGGATTTGTCT
  CGACCGCTTTATAAGAAGCCCCCTGCAGATTCCCGTGCACTTGGGGAGTGGGGGAAAGCC
  AGCAAACTCCAGCTCAACGAGGATGAACTGAAGCAGCAAGAAGAACTCATTGAGAGATAC
  GCCATCAATATTTACCTCAGTGACAGGATTTCCCTGCATCGACACATAGAGGATAAAAGA
  ATGTATGAGTGTAAGTCCCAGAAGTTCAACTATAGGACACTTCCTACCACCTCTGTTATC
  ATTGCTTTCTATAACGAAGCCTGGTCGACTTTGCTCCGTACCATTCACAGTGTTTTAGAA
  ACTTCTCCTGCAGTTCTTTTGAAAGAGATCATCTTGGTGGATGACTTGAGTGACAGAGTT
  TATTTGAAGACACAACTTGAAACTTACATCAGCAATCTTGATAGAGTACGCTTGATTAGG
  ACCAATAAGCGAGAGGGGCTGGTTAGGGCCCGTCTGATTGGGGCCACTTTCGCCACTGGG
  GACGTCCTCACTTTCCTGGATTGTCACTGTGAGTGTAATTCCGGTTGGCTGGAACCGCTT
  TTGGAAAGGATTGGGAGAGATGAAACAGCAGTTGTGTGTCCTGTTATAGACACAATTGAT
  TGGAATACTTTTGAATTCTATATGCAGATAGGGGAGCCCATGATTGGTGGGTTTGACTGG
  CGTTTAACATTTCAGTGGCATTCTGTCCCCAAACAGGAAAGGGACAGGCGGATATCAAGA
  ATTGACCCCATCAGATCACCTACCATGGCTGGAGGACTGTTTGCTGTCAGCAAGAAATAT
  TTTCAGTACCTTGGAACGTATGACACAGGAATGGAAGTGTGGGGAGGTGAAAACCTTGAG
  CTGTCTTTTAGGGTGTGGCAGTGTGGTGGCAAATTGGAGATCCACCCGTGTTCCCACGTG
  GGCCATGTGTTCCCCAAGCGGGCACCATATGCTCGCCCCAATTTCCTACAGAATACTGCT
  CGGGCAGCAGAAGTTTGGATGGATGAATACAAAGAGCACTTCTACAATAGAAACCCTCCA
  GCAAGAAAAGAAGCTTATGGTGATATTTCTGAAAGAAAATTACTACGAGAGCGGTTGAGA
  TGCAAGAGCTTTGACTGGTATTTGAAAAACGTTTTTCCTAATTTACATGTTCCAGAGGAT
  AGACCAGGCTGGCATGGGGCTATTCGCAGTAGAGGGATCTCGTCTGAATGTTTAGATTAT
  AATTCTCCTGACAACAACCCCACAGGTGCTAACCTTTCACTGTTTGGATGCCATGGTCAA
  GGAGGCAATCAATTCTTTGAATATACTTCAAACAAAGAAATAAGGTTTAATTCTGTGACA
  GAGTTATGTGCAGAGGTACCTGAGCAAAAAAATTATGTGGGAATGCAAAATTGTCCCAAA
  GATGGGTTCCCTGTACCAGCAAACATTATTTGGCATTTTAAAGAAGATGGAACTATTTTT
  CACCCACACTCAGGACTGTGTCTTAGTGCTTATCGGACACCGGAGGGCCAACCTGATGTA
  CAAATGAGAACTTGTGATGCTCTAGATAAAAATCAAATTTGGAGTTTTGAGAAATAG
  
  Clone variation with respect to NM_003774.4
  1670 g=>a
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003774 unedited
  TATTTCCCCCGCCCGTTGNCGCATTGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAA
  GCAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCG
  CGAATTCGGCACGAGGGGAGAGAGGAGTTGGGCTGTGCCGGAGGCCGAGGACCGAGAGGG
  CTCAGGTGACCCCTGGAAAGCCTGGGTGGCTGGAAAGGAGCCTAGCGCCTGCATGAAAGG
  AAGAACCTGCTGGGAAGTACCTGAGCTCGAGCTGTGGGTTCCGCCGCCCTTCCCCTGCGT
  GGTGGCTTGGTGGCCGCGTCTGCGCCTCAGCCCTGAGAATCCGGATGGCGGTGAGGTGGA
  CTTGGGCAGGCAAGAGCTGCCTGCTGCTGGCGTTTTTAACAGTGGCCTATATCTTCGTGG
  AGCTCTTGGTCTCTACTTTTCATGCCTCCGCAGGAGCCGGCCGTGCCAGGGAGCTGGGGT
  CAAGAAGGCTCTCAGACCTCCAGAAAAATACGGAGGATTTGTCTCGACCGCTTTATAAGA
  AGCCCCCTGCAGATTCCCGTGCACTTGGGGAGTGGGGGAAAGCCAGCAAACTCCAGCTCA
  ACGAGGATGAACTGAAGCAGCAAGAAGAACTCATTGAGAGATACGCCATCAATATTTACC
  TCAGTGACAGGATTTCCCTGCATCGACACATAGAGGATAAAAGAATGTATGAGTGTAAGT
  CCCAGAAGTTCAACTATAGGACACTTCCTACCACCTCTGTTATCATTGCTTTCTATAACG
  AAGCCTGGTCGACTTTGCTTCGTACCATTCACAGTGTTTTAGAAACTTCTCCTGCAGTTC
  TTTTGAAAGAGACATCNTGGTGGATGACTTGAGTGACAGAGNTTATTTGTAGACCAACTT
  GAAACTTACTCAGCATCTTGATAGAGACGCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003774 unedited
  NCGGTTTCACTATGNNACCGCGGCCGCATNCTANGATCGAGTTTTTTTTTTTTTTTTTTT
  ATCAGGCACACTTTTTATTTTACATCTTAAACAACATTACAAATACAAAAGGAAAAAAGT
  CAGAAACAACTCATCACAGAGGAAAAAAACATCATTCAGAAGAGATTAATCTGAACTTCA
  ACGTTCTTTGTGCTCATTTTAAAATTATTAAAACAGGAATTCAAAAGGACAAGCAAATAA
  AAACCAAGTATTTTATTAATTAAAATTGAGACCCTAAACCAACTAAGACTATACAACTTA
  AAAATAAGCTGTCTTCATCCTAGAAAAGTTTGATTTGCCATCTTATAATGAATATGCAGG
  AACTTACTAATGGGTAAGTAAACAAATTTTCTTTTACAAACAAGTTATTTTGAGTTATAG
  GGATCCTCCTGGTGACTAGATTTTTTTTAATGACTAAAAATGCCTATTTAGATAGTCAAC
  CTATCCGTAAAGTTGGACACTAAATGACATAGTGAACATTTAAAGTTGAAACTCTTTGTC
  TACCAAATATTTTCCTAAAACTGTTTTTAAGCCTATACATTAACTTAAAAGGTCAACTCT
  TAATTGTCTATAGCCAAAGAGAGCTTTGGTACCCATAAATTCGAATTAAGGAATCGGTTT
  TTTTAGATGTAGAATTACAGAGTATTTTTGGAATTAAATTGGAACGTGCCTCAATATGAA
  AATGTGGAAGTCCCACCTTTCTGGTATGTGCCCTATTATGGAGGGATGAACAGCCCTACC
  ATACTGGATTATTTGAATAAATAAAACACCCCCGGTAAAACTCCTCCTCAAAAAATGCTG
  GGGGCCCACTCGCCATTTTGGGGCGAAAAGTCCATAAAGGATTAAGGGGCTTTATTTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003774
• ORF Size: 1737 bp
• Insert Size: 5500
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003774.3, NP_003765.2
• RefSeq Size: 5360
• RefSeq ORF: 1737
• Locus ID: 8693
• Domains: RICIN, Glycos_transf_2
• Protein Pathways: Metabolic pathways, O-Glycan biosynthesis
• Gene Summary: This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon. Fusion transcripts, which combine part of this gene with the 5' exons of the neighboring POC1B (POC1 centriolar protein homolog B) gene, also exist. [provided by RefSeq, Dec 2010]