CBX4 (NM_003655) Human Untagged Clone

CAT#: SC117841

CBX4 (untagged)-Human chromobox homolog 4 (CBX4)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CBX4
• Synonyms: NBP16; PC2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC117841 sequence for NM_003655 edited (data generated by NextGen Sequencing)
  ATGGAGCTGCCAGCTGTTGGCGAGCACGTCTTCGCGGTGGAGAGCATCGAGAAGAAGCGG
  ATCCGCAAGGGCAGAGTGGAGTATCTGGTGAAATGGAGAGGCTGGTCGCCCAAATATAAC
  ACGTGGGAACCGGAGGAGAACATCCTGGACCCCAGGCTGCTGATCGCCTTCCAGAACAGG
  GAACGGCAGGAGCAGCTGATGGGATATCGGAAGAGAGGGCCGAAGCCCAAACCGCTAGTG
  GTGCAGGTGCCTACCTTTGCCCGTCGTTCCAATGTCCTGACCGGCCTCCAGGACTCCTCC
  ACTGACAACCGTGCCAAGCTGGATTTGGGCGCGCAGGGGAAGGGCCAGGGGCATCAGTAC
  GAGCTCAACAGCAAGAAGCACCACCAGTACCAGCCGCACAGCAAGGAGCGGGCGGGCAAG
  CCCCCGCCGCCGGGCAAGAGCGGCAAGTACTACTACCAGCTCAACAGCAAGAAGCACCAC
  CCCTACCAGCCCGACCCCAAAATGTACGACCTGCAGTACCAGGGCGGCCACAAGGAGGCG
  CCCAGCCCCACCTGCCCGGACCTGGGGGCCAAGAGCCACCCGCCCGACAAGTGGGCGCAA
  GGTGCGGGGGCCAAAGGCTACCTGGGGGCGGTGAAGCCCCTGGCCGGTGCGGCGGGTGCT
  CCAGGCAAAGGCTCCGAGAAGGGCCCCCCCAACGGAATGATGCCGGCCCCCAAAGAGGCT
  GTGACGGGCAACGGGATTGGGGGCAAGATGAAGATAGTCAAGAACAAGAACAAGAACGGA
  CGCATCGTGATCGTGATGAGCAAATACATGGAGAACGGCATGCAGGCGGTGAAGATCAAG
  TCCGGCGAGGTGGCAGAGGGGGAGGCTCGCTCCCCCAGCCACAAGAAGCGGGCAGCCGAC
  GAGCGCCACCCTCCTGCCGACAGGACTTTTAAAAAGGCGGCGGGCGCAGAGGAGAAGAAG
  GTGGAGGCGCCGCCCAAGAGGAGGGAGGAGGAGGTGTCCGGGGTTAGCGATCCGCAGCCC
  CAGGATGCCGGCTCCCGCAAGCTGTCCCCGACCAAGGAGGCCTTTGGAGAGCAGCCCCTG
  CAGCTCACCACCAAGCCCGACCTGCTTGCCTGGGACCCGGCCCGGAACACGCACCCGCCC
  TCACACCACCCGCACCCGCACCCCCATCACCACCACCACCACCACCACCACCACCACCAC
  GCCGTCGGCCTGAATCTCTCCCACGTGCGCAAGCGCTGCCTCTCCGAGACCCACGGCGAG
  CGCGAGCCCTGCAAGAAGCGGCTGACTGCGCGCAGCATCAGCACCCCCACCTGCCTGGGG
  GGCAGCCCAGCCGCTGAGCGCCCGGCCGACCTGCCACCAGCCGCCGCCCTCCCGCAGCCC
  GAGGTCATCCTGCTAGACTCAGACCTGGATGAACCCATAGACTTGCGCTGCGTCAAGACG
  CGCAGCGAGGCCGGGGAGCCGCCCAGCTCCCTCCAGGTGAAGCCCGAGACACCGGCGTCG
  GCGGCGGTGGCGGTNNNNNNNNNAGCGGCNCCCACCNNNNNNNNGGAGAAGCCTCCAGCC
  GAGGCCCAGGACGAACCTGCAGAGTCGCTGAGCGAGTTCAAGCCCTTCTTTGGGAATATA
  ATTATCACCGACGTCACCGCGAACTGCCTCACCGTTACTTTCAAGGAGTACGTGACGGTG
  TAG
  
  Clone variation with respect to NM_003655.2
  1515 g=>n;1516 g=>n;1517 c=>n;1518 g=>n;1519 g=>n;1520 c=>n;1521 g=>n;1522 g=>n;1523 c=>n;1530 a=>n;1537 a=>n;1538 c=>n;1539 g=>n;1540 a=>n;1541 c=>n;1542 g=>n;1543 g=>n;1544 c=>n
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003655 unedited
  TACTATAGGGCGGCCGCGAATTCGGCACGAGGGCGAGCCGGGAGCCGGGGCGGGCGCGGG
  CAGCGGCGGGCCGGCCGGGCTGTGCGGGGCGAGCGGCGGCGGCGGCGGGGGCGCTTCGGC
  CGGGGCGGCAGCTGGGCGCCGGCGGGAGCTAGCAGCGTCTGCAGCCGCGCCGGCCGCCAG
  CGCCCCGGCGCGCTCCGGCTCGGCCATGGAGCTGCCAGCTGTTGGCGAGCACGTCTTCGC
  GGTGGAGAGCATCGAGAAGAAGCGGATCCGCAAGGGCAGAGTGGAGTATCTGGTGAAATG
  GAGAGGCTGGTCGCCCAAATATAACACGTGGGAACCGGAGGAGAACATCCTGGACCCCAG
  GCTGCTGATCGCCTTCCAGAACAGGGAACGGCAGGAGCAGCTGATGGGATATCGGAAGAG
  AGGGCCGAAGCCCAAACCGCTAGTGGTGCAGGTGCCTACCTTTGCCCGTCGTTCCAATGT
  CCTGACCGGCCTCCAGGACTCCTCCACTGACAACCGTGCCAAGCTGGGATTGGGCGCGCA
  GGGGGAAGGGCCAGGGGCATCAGTACGAGCTCACAGCAGAAACACCCCAGTACAGCCGCA
  CAGAGGAGCGGGCGGCAAGCCCCGCGCCGGCAGAGCGGCAGTCTACTACAGCTCACAGCA
  GAGCACACCCCTACAGCCGACCCAAATGACGACTGCAGACCAGGCGGCCACAGAGGGCCA
  GCCCACTGCCGGACTTGGGGCCAAGACCACCGCCGACAGAGGCGCAGGGGGGGGGCCAAG
  GCTCTGGGGGCGGAAAACCCCGGCGGGGGGGGGGGCTCAGAAGGCTCCAAAAGCCCCCCC
  GGAAGACCCGGCCCAAAAGGTTGACGCCACGAATGGGGCAAATAAATCTCCAAAAACAAA
  CAGCCTCTTTCCTAAACCAATCAGAACGCTTCGCGGGGTAACCCCGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003655 unedited
  CCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTTTTCAACATCTCCATTTAATATTT
  ACATTCAAGCAGGTAATAGTTGGAAGCTTATAGTTTAGACATTTCTAGTAGCAGCAGTTT
  CTAGAGAGCTCGTGTAGCCTTTTAACAAACTTTTTTTTTTTTTTTTTTTGCACATAAAAA
  CAAGACATCCATGTGTACAGTATCAAAAAATATATACCAAGGTTACTGGTATTGCAGTTC
  GGGGAAGGGGAAAAAAGGGGAAAAAATGAAATCAACCGAAATACTGGATGGAGGGGAAAA
  AAGGTCAAAAAAAAATAGTTGGTCTGATATAGAATATAACATGATCTAGAGGAAACTCCA
  TAAATCTAGGTTTTTATATTTCAATATATAAATCCCTACAAATAAATATATATATAGCAG
  CCCGAAGGGGGGGGGTCGGGCCTTTTGAGCTCAAACAATACATTTCAATAATAACACCAC
  GTACAAACGGGAGTAGAGTCAGCACTTGACAAGTTAGCACGGTTAAAATATAATACTAGA
  ACTCTGAGGCCGGGCGCAGAGCTGCCCTGTCCGTTCCGGGGTCCATCTCCACCGGGGAAG
  GGCAGGAAAGGGCGACCCCCGCCGGCACCGCGTGGAAGGGGCCTCCCCCCAGGTCTGACA
  GCCGCCGCAGGGGGAACATGGTTACCTCCGCTCCGGGCGTCCTCACCCTGGGGGCCAGCC
  TGGGTCTCTCCCGGTTTGGCGGTTTGCAAAGAGGGGACCCCCCCCGAGGGCCCAGGGGCT
  ATCTCCCCGCCCCCCTGCGGGAATGGGCGTTTCCCTTCCAAGCCCCTCCGGGTTACACCG
  GACGTACTCCTTGAAAGCACAGGGGAAGGCCTCCTGGGCGCCCTGCGTGCAAACTTTTTT
  CCAAAAGAGGCTTGACACTCCCACCGCCTTGGGGGTCCTCCTGGCCCTGGCGGAGCTTCC
  CCCGCCGGCGNCGGGGCCTATCCCCCCCTCCCACTCCCGT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003655
• ORF Size: 1683 bp
• Insert Size: 2740
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_003655.2, NP_003646.2
• RefSeq Size: 2655
• RefSeq ORF: 1683
• Locus ID: 8535
• Domains: CHROMO
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: Component of a Polycomb group (PcG) multiprotein PRC1-like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. [UniProtKB/Swiss-Prot Function]