PCPTP1 (PTPRR) (NM_002849) Human Untagged Clone

CAT#: SC118370

PTPRR (untagged)-Human protein tyrosine phosphatase, receptor type, R (PTPRR), transcript variant 1


  "NM_002849" in other vectors (6)

Reconstitution Protocol

USD 1,110.00

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Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol PTPRR
Synonyms EC-PTP; PCPTP1; PTP-SL; PTPBR7; PTPRQ
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF sequence for NM_002849 edited
GGCGGCCGCGAATTCGGCACGAGGGCCTTGGCTTCTGGGCGTCCAGAAGGCCAGGCATTT
GCCGCCTCTGAGCGCTTCTGTTCCCCTTACCCGCAACCTCCTACTGCTCTTCCTCTCTCC
CTCTCTTAGGGAGGTTGAAGCTGGTGCTGGTTTCTGTCGGCGCCACAGACTGACTGCTCT
GCAAACCCCAGCCGAGGACCTGAATCCCGGAGACTAGAAGACCCTTGGCGGTGGCTCTTT
CTAATAGCACTTTACCTGAAGTGGGGTCGTGGTGGAGTTTCTCCTCCACCTCTCAATGCA
AACACTATGCGGAGAGCAGTCTGCTTCCCTGCGCTGTGCCTGCTCCTTAATCTTCACGCT
GCAGGGTGCTTTTCAGGAAACAATGATCATTTTTTGGCAATTAATCAGAAGAAGAGTGGG
AAGCCGGTATTCATTTATAAGCATTCACAAGACATTGAGAAGAGCCTGGATATAGCCCCA
CAAAAAATCTACAGACATAGCTACCATTCCTCTTCCGAAGCTCAAGTAAGCAAACGCCAC
CAGATTGTCAATTCAGCATTTCCTAGACCCGCATATGACCCGTCTCTCAATCTGCTGGCC
ATGGATGGTCAAGATCTTGAAGTGGAAAATCTCCCAATCCCAGCAGCAAATGTAATTGTG
GTGACACTGCAAATGGATGTAAACAAGCTGAACATAACCTTGCTTCGGATCTTCCGCCAA
GGAGTGGCTGCAGCTTTAGGACTCTTACCCCAGCAAGTGCACATCAATCGCCTCATTGGA
AAGAAGAACAGTATTGAACTGTTTGTGTCTCCCATAAACCGAAAAACAGGAATTTCTGAT
GCTCTGCCCTCTGAGGAAGTTCTTCGTTCACTTAATATCAATGTTTTGCATCAAAGTTTA
TCCCAGTTTGGAATTACAGAAGTCTCTCCTGAGAAAAATGTTTTACAAGGGCAGCATGAA
GCGGACAAAATCTGGAGCAAAGAAGGATTTTATGCTGTTGTCATTTTTCTCAGCATCTTT
GTTATTATAGTAACGTGTTTGATGATTCTTTACAGATTAAAAGAAAGATTTCAGCTTTCC
TTAAGACAAGACAAAGAGAAAAACCAGGAGATCCACCTATCGCCCATCACATTACAGCCA
GCACTGTCCGAGGCAAAGACAGTCCACAGCATGGTCCAACCTGAGCAGGCCCCAAAGGTA
CTGAATGTTGTCGTGGACCCTCAAGGCCGAGGTGCTCCTGAGATCAGAGCTACCACCGCT
ACCTCTGTTTGCCCTTCTCCTTTCAAAATGAAGCCCATAGGACTTCAAGAGAGAAGAGGG
TCCAACGTATCTCTTACATTGGACATGAGTAGCTTGGGGAACATTGAACCCTTTGTGTCT
ATACCAACACCACGGGAGAAGGTAGCAATGGAGTATCTGCAGTCAGCCAGCCGAATTCTC
ACAAGGTCTCAGCTGAGGGACGTCGTGGCAAGTTCACATTTACTCCAAAGTGAATTCATG
GAAATACCAATGAACTTTGTGGATCCCAAAGAAATTGATATTCCGCGTCATGGAACTAAA
AATCGCTATAAGACCATTTTACCAAATCCCCTCAGCAGAGTGTGTTTAAGACCAAAAAAT
GTAACCGATTCATTGAGCACCTACATTAATGCTAATTATATTAGGGGCTACAGTGGCAAG
GAGAAAGCCTTCATTGCCACGCAGGGCCCCATGATCAACACCGTGGATGATTTCTGGCAG
ATGGTTTGGCAGGAAGACAGCCCTGTGATTGTTATGATCACAAAACTCAAAGAAAAAAAT
GAGAAATGTGTGCTATACTGGCCGGAAAAGAGAGGGATATATGGAAAAGTTGAGGTTCTG
GTTATCAGTGTAAATGAATGTGATAACTACACCATTCGAAACCTTGTCTTAAAGCAAGGA
AGCCACACCCAACATGTGAAGCATTACTGGTACACCTCATGGCCTGATCACAAGACTCCA
GACAGTGCCCAGCCCCTCCTACAGCTCATGCTGGATGTAGAAGAAGACAGACTTGCTTCC
CAGGGCCGAGGGCCTGTGGTTGTCCACTGCAGTGCAGGAATAGGTAGAACAGGGTGTTTT
ATTGCTACATCCATTGGCTGTCAACAGCTGAAAGAAGAAGGAGTTGTGGATGCACTAAGC
ATTGTCTGCCAGCTTCGTATGGATAGAGGTGGAATGGTGCAAACCAGTGAGCAGTATGAA
TTTGTGCACCATGCTCTGTGCCTGTATGAGAGCAGACTTTCAGCAGAGACTGTCCAGTGA
GTCATTGAAGACTTGTCAGACCATCAATCTCTTGGGGTGATTAATCAAATTACCCACCCA
AGGCTTCTAGAAGGAGCTTCCTGCAATGGAAGGAAGGAGAAGCTCTGAAGCCCATGTATG
GCATGGATTGTGGAAGACTGGGCAACATATTTAAGATTTCCAGCTCCTTGTGTATATGAA
TGCATTTGTAAGCATCCCCCAAATTATTCTGAAGGTTTTTTGATGATGGAGGTATGATAG
GTTTATCACACAGCCTAAGGCAGATTTTGTTTTGTCTGTACTGACTCTATCTGCCACACA
GAATGTATGTATGTAATATTCAGTAATAAATGTCATCAGGTGATGACTGGATGAGCTGCT
GAAGACATTCGTATTATGTGTTAGATGCTTTAATGTTTGCAAAATCTGTCTTGTGAATGG
ACT
>OriGene 5' read for NM_002849 unedited
TGTAATACGACTCACTATAGGGCGGCCGCGACTTCGGCACGAGGGCCTTGGCTTCTGGGC
GTCCAGAAAGCCAGGCATTTGCCGCCTCTGAGCGCTTCTGTTCCCCTTACCCGCAACCTC
CTACTGCTCTTCCTCTCTCCCTCTCTTAGGGAGGTTGAAGCTGGTGCTGGTTTCTGTCGG
CGCCACAGACTGACTGCTCTGCAAACCCCAGCCGAGGACCTGAATCCCGGAGACTAGAAG
ACCCTTGGCGGTGGCTCTTTCTAATAGCACTTTACCTGAAGTGGGGTCGTGGTGGAGTTT
CTCCTCCACCTCTCAATGCAAACACTATGCGGAGAGCAGTCTGCTTCCCTGCGCTGTGCC
TGCTCCTTAATCTTCACGCTGCAGGGTGCTTTTCAGGAAACAATGATCATTTTTTGGCAA
TTAATCAGAAGAAGAGTGGGAAGCCGGTATTCATTTATAAGCATTCACAAGACATTGAGA
AGAGCCTGGATATAGCCCCACAAAAAATCTACAGACATAGCTACCATTCCTCTTCCGAAG
CTCAAGTAAGCAAACGCCACCAGATTGTCAATTCAGCATTTCCTAGACCCGCATATGACC
CGTCTCTCAATCTGCTGGCCATGGATGGTCAAGATCTTGAAGTGGAAAATCTCCCAATCC
CAGCAGCAAATGTAATTGTGGTGACACTGCNAATGGATGTAAACAAGCTGAACATAACCT
TGCTTCGGATCTTCCGCCAGGAGTGGCTGCANGCTTTAGACTCTTACCCCAGCAAGTGCA
CATCAATCGCCTCATTGGAAAGAAGACAGTATNGAACTNNGTTGTGTCTCCCCATAACCG
AAAAACANGAATTTCTGATGCTCCTGCCTCTGAGAAGTTCTTCGTCACTTATAATCATGT
TTGCATCAATTTATTCCAGTTGGAATTCAGAAGTCTCTCTGAAAAAATGTTACANGGNCN
CATGAAA
>OriGene 3' read for NM_002849 unedited
GCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAGTATTAAGAGTTTATT
GGCAGTATGAAACAAAGTCAACATTGCTGCATTAAAAATTCATATATGAGCAGAACAGCT
AGTGTTTGCTGAGGGTAGTTATTTTAATTTTTTTTGTCTCTTGAAGATTGAAAGCTTTCA
GAAATGTAAGGACATACATGGAAATGTCCTTATAAGGAGCCTCGAAAATGGGACAGATTA
TATCATTCCTGAAGGCATATACCTTTTGTTGAGAGAGAGATTCCAGGTAGATAGCATATT
CAAAAATCCCTTCTTAGCAAAAGAGAGACAAGTAGTTAAAACTCTTGATACTTCAGAGTT
GCTACAAATTTGTTTTTCCCTTTTAAAGTAAAATGACTCACGATGTGGAAATACAGTGGA
TAGAGTTCTGGAGCAGAAGCCACCTTTATGCCCAATAATAGAGAGTAAATACATATATAC
CCAATGACAATCATTGTGCTCTGTAATTGTTTGATAGGAGGGACTATAAATACACATTTA
ATAGGTAATATTATCAAGACACATTTCCATATAAAATAGTTACTGTTTTTGATTTTTGTT
TTTCAAAAACAAAGACTTCTCTGTTAAAAATCCATTAATCATCACTTGCAACTTTTAGCC
GCAAGATTCTGGTAACCTGAGAAAGGTAATAGCCACTTAAAACAGGACCAGTTTAACAGC
TGACAGTCCTTTTCACAGACAGATTTTTGCAACCCTAAAAGCTCTACCACATATCCGAAT
GTCTTCACCAGCTCATCCAGTTTTAACCTGAAGAACCTTTATTACGGATATTACCATACA
TCCTTTCTTGGGGGGCGAAAGAAGTTACTCCAGCACAACACAAAATTCTGCCTTAGGGTG
GGGAACAAAACCTATCTACCCCTCCTCTATTAAAAACCTTTCAAAATATTGGGGGGAAGC
CTAACAATGCTCTCTATTACCAAG
Restriction Sites NotI-NotI     
ACCN NM_002849
Insert Size 4040 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_002849.2, NP_002840.1
RefSeq Size 3492 bp
RefSeq ORF 1974 bp
Locus ID 5801
Cytogenetics 12q15
Domains Y_phosphatase, PTPc_motif
Protein Families Druggable Genome, Phosphatase, Transmembrane
Protein Pathways MAPK signaling pathway
Gene Summary 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]'
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1, also referred to as isoform alpha). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.

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