PCPTP1 (PTPRR) (NM_002849) Human Untagged Clone

CAT#: SC118370

PTPRR (untagged)-Human protein tyrosine phosphatase, receptor type, R (PTPRR), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTPRR
• Synonyms: EC-PTP; PCPTP1; PTP-SL; PTPBR7; PTPRQ
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_002849 edited
  GGCGGCCGCGAATTCGGCACGAGGGCCTTGGCTTCTGGGCGTCCAGAAGGCCAGGCATTT
  GCCGCCTCTGAGCGCTTCTGTTCCCCTTACCCGCAACCTCCTACTGCTCTTCCTCTCTCC
  CTCTCTTAGGGAGGTTGAAGCTGGTGCTGGTTTCTGTCGGCGCCACAGACTGACTGCTCT
  GCAAACCCCAGCCGAGGACCTGAATCCCGGAGACTAGAAGACCCTTGGCGGTGGCTCTTT
  CTAATAGCACTTTACCTGAAGTGGGGTCGTGGTGGAGTTTCTCCTCCACCTCTCAATGCA
  AACACTATGCGGAGAGCAGTCTGCTTCCCTGCGCTGTGCCTGCTCCTTAATCTTCACGCT
  GCAGGGTGCTTTTCAGGAAACAATGATCATTTTTTGGCAATTAATCAGAAGAAGAGTGGG
  AAGCCGGTATTCATTTATAAGCATTCACAAGACATTGAGAAGAGCCTGGATATAGCCCCA
  CAAAAAATCTACAGACATAGCTACCATTCCTCTTCCGAAGCTCAAGTAAGCAAACGCCAC
  CAGATTGTCAATTCAGCATTTCCTAGACCCGCATATGACCCGTCTCTCAATCTGCTGGCC
  ATGGATGGTCAAGATCTTGAAGTGGAAAATCTCCCAATCCCAGCAGCAAATGTAATTGTG
  GTGACACTGCAAATGGATGTAAACAAGCTGAACATAACCTTGCTTCGGATCTTCCGCCAA
  GGAGTGGCTGCAGCTTTAGGACTCTTACCCCAGCAAGTGCACATCAATCGCCTCATTGGA
  AAGAAGAACAGTATTGAACTGTTTGTGTCTCCCATAAACCGAAAAACAGGAATTTCTGAT
  GCTCTGCCCTCTGAGGAAGTTCTTCGTTCACTTAATATCAATGTTTTGCATCAAAGTTTA
  TCCCAGTTTGGAATTACAGAAGTCTCTCCTGAGAAAAATGTTTTACAAGGGCAGCATGAA
  GCGGACAAAATCTGGAGCAAAGAAGGATTTTATGCTGTTGTCATTTTTCTCAGCATCTTT
  GTTATTATAGTAACGTGTTTGATGATTCTTTACAGATTAAAAGAAAGATTTCAGCTTTCC
  TTAAGACAAGACAAAGAGAAAAACCAGGAGATCCACCTATCGCCCATCACATTACAGCCA
  GCACTGTCCGAGGCAAAGACAGTCCACAGCATGGTCCAACCTGAGCAGGCCCCAAAGGTA
  CTGAATGTTGTCGTGGACCCTCAAGGCCGAGGTGCTCCTGAGATCAGAGCTACCACCGCT
  ACCTCTGTTTGCCCTTCTCCTTTCAAAATGAAGCCCATAGGACTTCAAGAGAGAAGAGGG
  TCCAACGTATCTCTTACATTGGACATGAGTAGCTTGGGGAACATTGAACCCTTTGTGTCT
  ATACCAACACCACGGGAGAAGGTAGCAATGGAGTATCTGCAGTCAGCCAGCCGAATTCTC
  ACAAGGTCTCAGCTGAGGGACGTCGTGGCAAGTTCACATTTACTCCAAAGTGAATTCATG
  GAAATACCAATGAACTTTGTGGATCCCAAAGAAATTGATATTCCGCGTCATGGAACTAAA
  AATCGCTATAAGACCATTTTACCAAATCCCCTCAGCAGAGTGTGTTTAAGACCAAAAAAT
  GTAACCGATTCATTGAGCACCTACATTAATGCTAATTATATTAGGGGCTACAGTGGCAAG
  GAGAAAGCCTTCATTGCCACGCAGGGCCCCATGATCAACACCGTGGATGATTTCTGGCAG
  ATGGTTTGGCAGGAAGACAGCCCTGTGATTGTTATGATCACAAAACTCAAAGAAAAAAAT
  GAGAAATGTGTGCTATACTGGCCGGAAAAGAGAGGGATATATGGAAAAGTTGAGGTTCTG
  GTTATCAGTGTAAATGAATGTGATAACTACACCATTCGAAACCTTGTCTTAAAGCAAGGA
  AGCCACACCCAACATGTGAAGCATTACTGGTACACCTCATGGCCTGATCACAAGACTCCA
  GACAGTGCCCAGCCCCTCCTACAGCTCATGCTGGATGTAGAAGAAGACAGACTTGCTTCC
  CAGGGCCGAGGGCCTGTGGTTGTCCACTGCAGTGCAGGAATAGGTAGAACAGGGTGTTTT
  ATTGCTACATCCATTGGCTGTCAACAGCTGAAAGAAGAAGGAGTTGTGGATGCACTAAGC
  ATTGTCTGCCAGCTTCGTATGGATAGAGGTGGAATGGTGCAAACCAGTGAGCAGTATGAA
  TTTGTGCACCATGCTCTGTGCCTGTATGAGAGCAGACTTTCAGCAGAGACTGTCCAGTGA
  GTCATTGAAGACTTGTCAGACCATCAATCTCTTGGGGTGATTAATCAAATTACCCACCCA
  AGGCTTCTAGAAGGAGCTTCCTGCAATGGAAGGAAGGAGAAGCTCTGAAGCCCATGTATG
  GCATGGATTGTGGAAGACTGGGCAACATATTTAAGATTTCCAGCTCCTTGTGTATATGAA
  TGCATTTGTAAGCATCCCCCAAATTATTCTGAAGGTTTTTTGATGATGGAGGTATGATAG
  GTTTATCACACAGCCTAAGGCAGATTTTGTTTTGTCTGTACTGACTCTATCTGCCACACA
  GAATGTATGTATGTAATATTCAGTAATAAATGTCATCAGGTGATGACTGGATGAGCTGCT
  GAAGACATTCGTATTATGTGTTAGATGCTTTAATGTTTGCAAAATCTGTCTTGTGAATGG
  ACT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002849 unedited
  TGTAATACGACTCACTATAGGGCGGCCGCGACTTCGGCACGAGGGCCTTGGCTTCTGGGC
  GTCCAGAAAGCCAGGCATTTGCCGCCTCTGAGCGCTTCTGTTCCCCTTACCCGCAACCTC
  CTACTGCTCTTCCTCTCTCCCTCTCTTAGGGAGGTTGAAGCTGGTGCTGGTTTCTGTCGG
  CGCCACAGACTGACTGCTCTGCAAACCCCAGCCGAGGACCTGAATCCCGGAGACTAGAAG
  ACCCTTGGCGGTGGCTCTTTCTAATAGCACTTTACCTGAAGTGGGGTCGTGGTGGAGTTT
  CTCCTCCACCTCTCAATGCAAACACTATGCGGAGAGCAGTCTGCTTCCCTGCGCTGTGCC
  TGCTCCTTAATCTTCACGCTGCAGGGTGCTTTTCAGGAAACAATGATCATTTTTTGGCAA
  TTAATCAGAAGAAGAGTGGGAAGCCGGTATTCATTTATAAGCATTCACAAGACATTGAGA
  AGAGCCTGGATATAGCCCCACAAAAAATCTACAGACATAGCTACCATTCCTCTTCCGAAG
  CTCAAGTAAGCAAACGCCACCAGATTGTCAATTCAGCATTTCCTAGACCCGCATATGACC
  CGTCTCTCAATCTGCTGGCCATGGATGGTCAAGATCTTGAAGTGGAAAATCTCCCAATCC
  CAGCAGCAAATGTAATTGTGGTGACACTGCNAATGGATGTAAACAAGCTGAACATAACCT
  TGCTTCGGATCTTCCGCCAGGAGTGGCTGCANGCTTTAGACTCTTACCCCAGCAAGTGCA
  CATCAATCGCCTCATTGGAAAGAAGACAGTATNGAACTNNGTTGTGTCTCCCCATAACCG
  AAAAACANGAATTTCTGATGCTCCTGCCTCTGAGAAGTTCTTCGTCACTTATAATCATGT
  TTGCATCAATTTATTCCAGTTGGAATTCAGAAGTCTCTCTGAAAAAATGTTACANGGNCN
  CATGAAA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002849 unedited
  GCGGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTTTAGTATTAAGAGTTTATT
  GGCAGTATGAAACAAAGTCAACATTGCTGCATTAAAAATTCATATATGAGCAGAACAGCT
  AGTGTTTGCTGAGGGTAGTTATTTTAATTTTTTTTGTCTCTTGAAGATTGAAAGCTTTCA
  GAAATGTAAGGACATACATGGAAATGTCCTTATAAGGAGCCTCGAAAATGGGACAGATTA
  TATCATTCCTGAAGGCATATACCTTTTGTTGAGAGAGAGATTCCAGGTAGATAGCATATT
  CAAAAATCCCTTCTTAGCAAAAGAGAGACAAGTAGTTAAAACTCTTGATACTTCAGAGTT
  GCTACAAATTTGTTTTTCCCTTTTAAAGTAAAATGACTCACGATGTGGAAATACAGTGGA
  TAGAGTTCTGGAGCAGAAGCCACCTTTATGCCCAATAATAGAGAGTAAATACATATATAC
  CCAATGACAATCATTGTGCTCTGTAATTGTTTGATAGGAGGGACTATAAATACACATTTA
  ATAGGTAATATTATCAAGACACATTTCCATATAAAATAGTTACTGTTTTTGATTTTTGTT
  TTTCAAAAACAAAGACTTCTCTGTTAAAAATCCATTAATCATCACTTGCAACTTTTAGCC
  GCAAGATTCTGGTAACCTGAGAAAGGTAATAGCCACTTAAAACAGGACCAGTTTAACAGC
  TGACAGTCCTTTTCACAGACAGATTTTTGCAACCCTAAAAGCTCTACCACATATCCGAAT
  GTCTTCACCAGCTCATCCAGTTTTAACCTGAAGAACCTTTATTACGGATATTACCATACA
  TCCTTTCTTGGGGGGCGAAAGAAGTTACTCCAGCACAACACAAAATTCTGCCTTAGGGTG
  GGGAACAAAACCTATCTACCCCTCCTCTATTAAAAACCTTTCAAAATATTGGGGGGAAGC
  CTAACAATGCTCTCTATTACCAAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002849
• Insert Size: 4040 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002849.2, NP_002840.1
• RefSeq Size: 3492 bp
• RefSeq ORF: 1974 bp
• Locus ID: 5801
• Cytogenetics: 12q15
• Domains: Y_phosphatase, PTPc_motif
• Protein Families: Druggable Genome, Phosphatase, Transmembrane
• Protein Pathways: MAPK signaling pathway
• Gene Summary: 'The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]'
  Transcript Variant: This variant (1) represents the longest transcript and encodes the longest protein (isoform 1, also referred to as isoform alpha). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.