EXOSC10 (NM_002685) Human Untagged Clone

CAT#: SC118513

EXOSC10 (untagged)-Human exosome component 10 (EXOSC10), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EXOSC10
• Synonyms: p2; p3; p4; PM-Scl; PM/Scl-100; PMSCL; PMSCL2; RRP6; Rrp6p
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC118513 sequence for NM_002685 edited (data generated by NextGen Sequencing)
  ATGGCGCCACCCAGTACCCGGGAGCCCAGGGTCCTGTCGGCGACCAGCGCAACCAAATCC
  GACGGAGAGATGGTGCTGCCAGGCTTCCCGGACGCCGACAGCTTTGTGAAGTTTGCTCTT
  GGGTCCGTGGTGGCAGTCACCAAGGCATCTGGGGGCCTACCACAGTTTGGCGATGAGTAT
  GATTTTTACCGAAGTTTTCCTGGCTTCCAAGCATTTTGCGAAACACAGGGAGACAGGTTG
  CTTCAGTGCATGAGCAGAGTAATGCAGTACCATGGGTGTCGCAGCAACATTAAGGATCGA
  AGTAAAGTGACTGAGCTGGAAGACAAGTTTGATTTACTAGTTGATGCCAATGATGTAATT
  CTGGAGAGAGTGGGTATTTTACTGGATGAAGCCTCAGGTGTAAACAAGAATCAACAGCCT
  GTCCTCCCTGCCGGCTTGCAGGTCCCCAAAACGGTAGTGTCCAGCTGGAACCGTAAGGCA
  GCAGAATATGGCAAAAAAGCAAAATCTGAAACTTTCCGGCTGCTTCATGCAAAAAATATC
  ATCCGACCTCAGCTCAAGTTTCGAGAGAAGATTGACAATTCCAACACACCATTTCTTCCT
  AAAATCTTCATCAAACCCAATGCTCAGAAACCTCTCCCTCAAGCTCTCTCTAAGGAAAGG
  CGGGAACGCCCACAGGATCGTCCTGAGGACTTGGACGTCCCCCCTGCACTGGCTGATTTC
  ATCCATCAGCAGAGAACCCAGCAGGTTGAGCAAGACATGTTTGCACATCCTTATCAATAT
  GAACTAAATCACTTTACCCCAGCAGATGCAGTGCTTCAAAAGCCACAACCCCAGTTATAC
  AGACCTATAGAAGAGACACCATGCCATTTCATATCCTCCCTGGATGAACTCGTGGAACTC
  AACGAAAAGCTCTTGAATTGTCAGGAATTTGCAGTTGACTTGGAGCACCACTCTTACAGG
  AGCTTCCTGGGACTGACCTGCCTGATGCAAATTTCTACTCGGACGGAAGACTTCATCATT
  GACACCCTCGAGCTTCGAAGTGACATGTACATTCTCAATGAGAGCCTCACAGACCCAGCC
  ATCGTTAAGGTCTTTCATGGTGCTGATTCAGACATAGAATGGCTACAGAAAGACTTTGGG
  TTGTATGTAGTAAACATGTTTGATACTCATCAGGCAGCACGCCTTCTTAACCTGGGCAGG
  CACTCACTCGATCATCTCCTGAAACTCTACTGCAACGTGGACTCAAACAAGCAATATCAG
  CTGGCTGATTGGAGAATACGCCCTCTGCCCGAGGAGATGCTCAGCTACGCCCGGGATGAC
  ACCCATTACCTGCTATATATCTATGACAAAATGAGGCTGGAGATGTGGGAGCGCGGCAAC
  GGGCAGCCCGTGCAGCTGCAGGTGGTGTGGCAACGGAGCAGGGACATCTGCCTCAAGAAA
  TTCATCAAACCTATCTTCACGGATGAGTCCTACCTTGAACTCTATAGGAAGCAGAAGAAG
  CACCTTAACACACAGCAGTTGACAGCCTTTCAGCTGCTGTTTGCCTGGAGGGATAAAACA
  GCTCGCAGGGAAGATGAAAGTTACGGATATGTACTGCCAAACCACATGATGCTGAAAATA
  GCTGAAGAACTGCCTAAGGAACCTCAGGGCATCATAGCTTGCTGCAACCCAGTACCGCCC
  CTTGTGCGGCAGCAGATCAACGAAATGCACCTTTTAATCCAGCAGGCCCGAGAGATGCCC
  CTGCTCAAGTCTGAAGTTGCAGCCGGAGTGAAGAAGAGCGGACCGCTGCCCAGTGCTGAG
  AGATTGGAGAATGTTCTCTTTGGACCTCACGACTGCTCCCATGCCCCTCCGGATGGCTAT
  CCAATCATCCCAACCAGTGGATCTGTGCCAGTTCAGAAGCAGGCGAGCCTCTTCCCTGAT
  GAAAAAGAAGATAACTTGCTGGGTACCACATGCCTGATTGCCACAGCTGTCATCACGTTA
  TTTAATGAACCTAGTGCTGAAGACAGTAAAAAGGGTCCATTGACAGTTGCACAGAAAAAA
  GCCCAGAACATCATGGAGTCCTTTGAAAATCCATTTAGGATGNTCAGCAACCGTTGGAAG
  CTGGCCCAGGTACAAGTACAAAAAGACTCTAAAGAAGCTGTCAAGAAGAAGGCAGCTGAG
  CAAACAGCTGCCCGGGAACAGGCAAAGGAGGCGTGCAAAGCTGCAGCAGAACAGGCCATC
  TCCGTCCGACAGCAGGTCGTGCTAGAAAATGCTGCAAAGAAGAGAGAGCGAGCAACAAGC
  GACCCAAGGACCACAGAACAGAAACAAGAGAAGAAACGACTCAAAATTTCCAAGAAGCCA
  AAGGACCCAGAGCCACCAGAAAAAGAGTTTACGCCTTACGACTACAGCCAGTCAGACTTC
  AAGGCTTTTGCTGGAAACAGCAAATCCAAAGTTTCTTCTCAGTTTGATCCAAATAAACAG
  ACCCCGTCTGGCAAGAAATGCATTGCAGCCAAAAAAATTAAACAGTCGGTGGGAAACAAA
  AGCATGTCCTTTCCAACTGGAAAGTCAGACAGAGGCTTCAGGTACAACTGGCCACAGAGA
  TAG
  
  Clone variation with respect to NM_002685.2
  1389 g=>c;2083 a=>n;2094 c=>t
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002685 unedited
  GTAATACGACTCACTTATAGGGCGGCCGCGATTCGGCACGAGGTGAAAAATGGCGCCACC
  CAGTACCCGGGAGCCCAGGGTCCTGTCGGCGACCAGCGCAACCAAATCCGACGGAGAGAT
  GGTGCTGCCAGGCTTCCCGGACGCCGACAGCTTTGTGAAGTTTGCTCTTGGGTCCGTGGT
  GGCAGTCACCAAGGCATCTGGGGGCCTACCACAGTTTGGCGATGAGTATGATTTTTACCG
  AAGTTTTCCTGGCTTCCAAGCATTTTGCGAAACACAGGGAGACAGGTTGCTTCAGTGCAT
  GAGCAGAGTAATGCAGTACCATGGGTGTCGCAGCAACATTAAGGATCGAAGTAAAGTGAC
  TGAGCTGGAAGACAAGTTTGATTTACTAGTTGATGCCAATGATGTAATTCTGGAGAGAGT
  GGGTATTTTACTGGATGAAGCCTCAGGTGTAAACAAGAATCAACAGCCTGTCCTCCCTGC
  CGGCTTGCAGGTCCCCAAAACGGTAGTGTCCAGCTGGAACCGTAAGGCAGCAGAATATGG
  CAAAAAAGCAAAATCTGAAACTTTCCGGCTGCTTCATGCAAAAAATATCATCCGACCTCA
  GCTCAAGTTTCGAGAGAAGATTGACAATTCCAACACACCATTTCTTCCTAAAATCTTCAT
  CAAACCCAATGCTCAGAAACCTCTCCCTCAAGCTCTCTCTAAGGAAGGCGGGAACGCCCA
  CAGGATCGTCCTGAGACTTGGACGTCCCCCCTGCACTGGCTGATTTCATCCATCAGCAGA
  GAACCCAGCANGTTGAGCAAGAACATGTTGCACATNCCTATCAATATGAACTANATCACC
  TTTACCCCAGCAGATGCAGTGCTTCAAAAGCCACACCCNCAGTATACAGACTATAGAAGA
  GACACATGCCATTTCTNATCCTNCCTGGATGGACTCGTGGGACTCACC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_002685 unedited
  CCGCGGCCGCAATCTANAGTCGAGTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTTT
  TCTTCAGAAAAAATTTTAATGGTTTAAAAATATGTTTGTACAAAAGCAGCACCAGCTTTT
  GGGGCTTCCGGTCCACAGGCGCCACGTGTTTTCCAGGACTATTTTTGGGGCCAGTTGTAC
  CTGAAGCCTTTGTCTGACTTTCCAGTTGGAAAGGACATGCTTTTGTTTCCCACCGACTGT
  TTAATTTTTTTGGCTGCAATGCATTTTTTGCCAAACGGGGTCTGTTTATTTGGATCAAAC
  TGAAAAAAAACTTTGGATTTGCTGTTTCCAGCAAAAGCCTTGAAGTCTGACTGGCTGTAG
  TCGTAAGGCGTAAACTCTTTTTCTGGGGGCTCTGGGTCCTTTGGCTTCTTGGAAATTTTG
  AGTCGTTTCTTCTCTTGTTTCTGTTCTGGGGCCCTTGGGTCGCTTGTTGCTCGCTCTCTC
  TTCTTTGCAGCATTTTCTAACACGACCTGCTGTCGGACGGAAATGGCCTGTTCTGCTGCA
  GCTTTGCACGCCTCCTTTGCCTGTTCCCGGGCAGCTGTTTGCTCAACTGCCTTCTTCTTG
  ACAGCTTCTTTAGAGCCTTTTTGCCCTTGCACCTGGGCCAACTTCCAACGGTTGCTGATT
  TCATAAAATTTGGTGGATGGATCCAACCTTCCTGCCTGAAAACGGAAGCCCGGTGGCCCA
  ATGAGGGCAAAAACCTCCTTAAAGGGTTTTTAAAGGACCCCATGATGTTCTCGGGTTTTT
  TTTCGGGCACCTGGAAAGGGACCCTTTTTACTGTTTTAACACTTAGGCCATTAAAAAACC
  GGAAGACCAGCGGGGCAATAGAGCTGGGGGCCCCAACCAGTTATTTCTTTTTAACGGGAA
  AAGGTCCCCTTCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002685
• Insert Size: 2880 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002685.2, NP_002676.1
• RefSeq Size: 2759 bp
• RefSeq ORF: 2583 bp
• Locus ID: 5394
• Cytogenetics: 1p36.22
• Domains: HRDC, 3_5_exonuclease
• Protein Pathways: RNA degradation
• Gene Summary: ''
  Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.