Kv1.6 (KCNA6) (NM_002235) Human Untagged Clone

CAT#: SC118766

KCNA6 (untagged)-Human potassium voltage-gated channel, shaker-related subfamily, member 6 (KCNA6)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: KCNA6
• Synonyms: HBK2; KV1.6; PPP1R96
• Vector: pCMV6-XL6
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_002235, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGAGATCGGAGAAATCCCTTACGCTGGCGGCGCCGGGGGAGGTCCGTGGGCCGGAGGGAGAGCAACAGG
  ATGCGGGAGACTTCCCGGAGGCCGGCGGGGGCGGGGGCTGCTGTAGTAGCGAGCGGCTGGTGATCAATAT
  CTCCGGGCTGCGCTTTGAGACACAATTGCGCACCCTGTCGCTGTTTCCGGACACGCTGCTCGGAGACCCT
  GGCCGGCGAGTCCGCTTCTTCGACCCCCTGAGGAACGAGTACTTCTTCGACCGCAACCGGCCCAGCTTCG
  ACGCCATCCTCTACTACTACCAGTCTGGGGGCCGCCTGCGGAGGCCGGTCAACGTGCCCCTGGACATTTT
  CCTGGAGGAGATCCGCTTCTACCAGCTGGGGGACGAGGCCCTGGCGGCCTTCCGGGAGGACGAGGGCTGC
  CTGCCCGAAGGTGGCGAGGACGAGAAGCCGCTGCCCTCCCAGCCCTTCCAGCGCCAGGTGTGGCTGCTCT
  TTGAGTACCCAGAGAGCTCTGGGCCGGCCAGGGGCATCGCCATCGTCTCCGTGTTGGTCATTCTCATCTC
  CATAGTCATCTTTTGCCTGGAGACCTTACCCCAGTTCCGTGTAGATGGTCGAGGTGGAAACAATGGTGGT
  GTGAGTCGAGTCTCCCCAGTTTCCAGGGGGAGTCAGGAGGAAGAGGAGGATGAAGACGATTCCTACACAT
  TTCATCATGGCATCACCCCTGGGGAAATGGGGACCGGGGGCTCCTCCTCACTCAGTACTCTTGGGGGCTC
  CTTCTTTACAGACCCCTTCTTTCTGGTGGAGACGCTGTGCATTGTCTGGTTCACTTTTGAGCTCCTGGTG
  CGCTTCTCCGCCTGCCCTAGCAAGCCGGCCTTCTTCCGGAACATCATGAACATCATTGACTTGGTGGCTA
  TCTTCCCCTACTTCATCACCCTGGGCACTGAGCTGGTGCAGCAGCAGGAGCAGCAACCAGCCAGTGGAGG
  AGGCGGCCAGAATGGGCAGCAGGCCATGTCCCTGGCCATCCTCCGAGTCATCCGCCTGGTCCGGGTGTTC
  CGCATCTTCAAGCTCTCCCGCCACTCCAAGGGGCTGCAGATCCTGGGCAAGACCTTGCAGGCCTCCATGA
  GGGAGCTGGGGCTGCTCATCTTCTTCCTCTTCATCGGGGTCATCCTCTTCTCCAGTGCCGTCTACTTCGC
  AGAGGCTGACGATGACGATTCGCTTTTTCCCAGCATCCCGGATGCCTTCTGGTGGGCAGTGGTTACAATG
  ACCACGGTAGGTTACGGGGACATGTACCCCATGACTGTGGGGGGAAAGATCGTGGGCTCGCTGTGTGCCA
  TCGCTGGGGTCCTCACCATTGCCCTGCCTGTGCCCGTCATCGTCTCCAACTTCAACTACTTCTACCACCG
  GGAGACGGAGCAGGAGGAGCAAGGCCAGTATACCCACGTCACTTGTGGGCAGCCTGCGCCGGACCTGAGG
  GCAACTGACAACGGACTTGGCAAGCCTGACTTCCCCGAGGCTAACCGGGAACGGAGACCCAGCTACCTTC
  CTACACCACATCGGGCCTATGCAGAGAAAAGAATGCTCACGGAGGTCTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_002235 unedited
  TCTTTACCCGCCCGTTGCCGCATTGGGCGGTAGGCGTGTACGGTGGGAGGTCTATATAAG
  CAGAGCTCATTTAGGTGACACTATAGAATACAAGCTACTTGTTCTTTTTGCAGCGGCCGC
  GAATTCGGCACGAGGGAACCAAATCCCCAGCGCCCAGGTCACCTCCCCAGACCCAGCCTT
  GCAGGGACCAGGGCTTTAGGGCTCACGGACCCAACGGCCAGGTCAGACCGCGAACCGGGA
  GGAGCGCGGGCCCCACCCTAAAGAGGGCGCAGCCGGGAGCTGGGGAGCGGGTGCCGCGCT
  CCAGAGATTGTGTCGTGGGCGCCGTCCTAGTGGCGGGGAGCGCACCTCCGAGGGGGCATG
  AGATCGGAGAAATCCCTTACGCTGGCGGCGCCGGGGGAGGTCCGTGGGCCGGAGGGAGAG
  CAACAGGATGCGGGAGACTTCCCGGAGGCCGGCGGGGGCGGGGGCTGCTGTAGTAGCGAG
  CGGCTGGTGATCAATATCTCCGGGCTGCGCTTTGAGACACAATTGCGCACCCTGTCGCTG
  TTTCCGGACACGCTGCTCGGAGACCCTGGCCGGCGAGTCCGCTTCTTCGACCCCCTGAGG
  AACGAGTACTTCTTCGACCGCAACCGGCCCAGCTTCGACGCCATCCTCTACTACTACCAG
  TCTGGGGGCCGCCTGCGGAGGCCGGTCAACGTGCCCCTGGACATTTTCCTGGAGGAGATC
  CGCTTCTACCAGCTGGGGGACGAGGCCCTGGCGGCCTTCCGGGAGGACGAGGGCTGCCTG
  CCCGAAGTGGCGAGGACGAGAAGCCGCTGCCCTCCCAGCCCTTCCAGCGCCAGGTGTGGC
  TGCTCTTTGAGTACCCAGAGAGCTCTGGGCCGGCCAGGGGCATCGNCATCGTCTCCGTGT
  TGGTCATTCTCATCTCCATAGTCATCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_002235
• Insert Size: 4700 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_002235.2, NP_002226.1
• RefSeq Size: 5982 bp
• RefSeq ORF: 5982 bp
• Locus ID: 3742
• Cytogenetics: 12p13.32
• Domains: BTB, K_tetra, ion_trans
• Protein Families: Druggable Genome, Ion Channels: Potassium, Transmembrane
• Gene Summary: 'Potassium channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. Four sequence-related potassium channel genes - shaker, shaw, shab, and shal - have been identified in Drosophila, and each has been shown to have human homolog(s). This gene encodes a member of the potassium channel, voltage-gated, shaker-related subfamily. This member contains six membrane-spanning domains with a shaker-type repeat in the fourth segment. It belongs to the delayed rectifier class. The coding region of this gene is intronless, and the gene is clustered with genes KCNA1 and KCNA5 on chromosome 12. [provided by RefSeq, Jul 2008]'