OB Cadherin (CDH11) (NM_001797) Human Untagged Clone

CAT#: SC119023

CDH11 (untagged)-Human cadherin 11, type 2, OB-cadherin (osteoblast) (CDH11)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDH11
• Synonyms: CAD11; CDHOB; ESWS; OB; OSF-4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001797 edited
  GAATCGGCACGAGGGTCAAGAAAAACGCGGGCGGGCAGGCCGAAGAGGAAATCACTGTGT
  TTTCAGCTCAGCGGCCCTGTGACATTCCTTCGTGTTGTCATTTGTTGAGTGACCAATCAG
  ATGGGTGGAGTGTGTTACAGAAATTGGCAGCAAGTATCCAATGGGTGAAGAAGAAGCTAA
  CTGGGGACGTGGGCAGCCCTGACGTGATGAGCTCAACCAGCAGAGACATTCCATCCCAAG
  AGAGGTCTGCGTGACGCGTCCGGGAGGCCACCCTCAGCAAGACCACCGTACAGTTGGTGG
  AAGGGGTGACAGCTGCATTCTCCTGTGCCTACCACGTAACCAAAAATGAAGGAGAACTAC
  TGTTTACAAGCCGCCCTGGTGTGCCTGGGCATGCTGTGCCACAGCCATGCCTTTGCCCCA
  GAGCGGCGGGGGCACCTGCGGCCTTCCTTCCATGGGCACCATGAGAAGGGCAAGGAGGGG
  CAGGTGCTACAGCGCTCCAAGCGTGGCTGGGTCTGGAACCAGTTCTTCGTGATAGAGGAG
  TACACCGGGCCTGACCCCGTGCTTGTGGGCAGGCTTCATTCAGATATTGACTCTGGTGAT
  GGGAACATTAAATACATTCTCTCAGGGGAAGGAGCTGGAACCATTTTTGTGATTGATGAC
  AAATCAGGGAACATTCATGCCACCAAGACGTTGGATCGAGAAGAGAGAGCCCAGTACACG
  TTGATGGCTCAGGCGGTGGACAGGGACACCAATCGGCCACTGGAGCCACCGTCGGAATTC
  ATTGTCAAGGTCCAGGACATTAATGACAACCCTCCGGAGTTCCTGCACGAGACCTATCAT
  GCCAACGTGCCTGAGAGGTCCAATGTGGGAACGTCAGTAATCCAGGTGACAGCTTCAGAT
  GCAGATGACCCCACTTATGGAAATAGCGCCAAGTTAGTGTACAGTATCCTCGAAGGACAA
  CCCTATTTTTCGGTGGAAGCACAGACAGGTATCATCAGAACAGCCCTACCCAACATGGAC
  AGGGAGGCCAAGGAGGAGTACCACGTGGTGATCCAGGCCAAGGACATGGGTGGACATATG
  GGCGGACTCTCAGGGACAACCAAAGTGATGATCACACTGACCGATGTCAATGACAACCCA
  CCAAAGTTTCCGCAGAGCGTATACCAGATGTCTGTGTCAGAAGCAGCCGTCCCTGGGGAG
  GAAGTAGGAAGAGTGAAAGCTAAAGATCCAGACATTGGAGAAAATGGCTTAGTCACATAC
  AATATTGTTGATGGAGATGGTATGGAATCATTTGAAATCACAACGGACTATGAAACACAG
  GAGGGGGTGATAAAGCTGAAAAAGCCTGTAGATTTTGAAACCAAAAGAGCCTATAGCTTG
  AAGGTAGAGGCAGCCAACGTGCACATCGACCCGAAGTTTATCAGCAATGGCCCTTTCAAG
  GACACTGTGACCGTCAAGATCGCAGTAGAAGATGCTGATGAGCCCCCTATGTTCTTGGCC
  CCAAGTTACATCCACGAAGTCCAAGAAAATGCAGCTGCTGGCACCGTGGTTGGGAGAGTG
  CATGCCAAAGACCCTGATGCTGCCAACAGCCCGATAAGGTATTCCATCGATCGTCACACT
  GACCTCGACAGATTTTTCACTATTAATCCAGAGGATGGTTTTATTAAAACTACAAAACCT
  CTGGATAGAGAGGAAACAGCCTGGCTCAACATCACTGTCTTTGCAGCAGAAATCCACAAT
  CGGCATCAGGAAGCCAAAGTCCCAGTGGCCATTAGGGTCCTTGATGTCAACGATAATGCT
  CCCAAGTTTGCTGCCCCTTATGAAGGTTTCATCTGTGAGAGTGATCAGACCAAGCCACTT
  TCCAACCAGCCAATTGTTACAATTAGTGCAGATGACAAGGATGACACGGCCAATGGACCA
  AGATTTATCTTCAGCCTACCCCCTGAAATCATTCACAATCCAAATTTCACAGTCAGAGAC
  AACCGAGATAACACAGCAGGCGTGTACGCCCGGCGTGGAGGGTTCAGTCGGCAGAAGCAG
  GACTTGTACCTTCTGCCCATAGTGATCAGCGATGGCGGCATCCCGCCCATGAGTAGCACC
  AACACCCTCACCATCAAAGTCTGCGGGTGCGACGTGAACGGGGCACTGCTCTCCTGCAAC
  GCAGAGGCCTACATTCTGAACGCCGGCCTGAGCACAGGCGCCCTGATCGCCATCCTCGCC
  TGCATCGTCATTCTCCTGGTCATTGTAGTATTGTTTGTGACCCTGAGAAGGCAAAAGAAA
  GAACCACTCATTGTCTTTGAGGAAGAAGATGTCCGTGAGAACATCATTACTTATGATGAT
  GAAGGGGGTGGGGAAGAAGACACAGAAGCCTTTGATATTGCCACCCTCCAGAATCCTGAT
  GGTATCAATGGATTTATCCCCCGCAAAGACATCAAACCTGAGTATCAGTACATGCCTAGA
  CCTGGGCTCCGGCCAGCGCCCAACAGCGTGGATGTCGATGACTTCATCAACACGAGAATA
  CAGGAGGCAGACAATGACCCCACGGCTCCTCCTTATGACTCCATTCAAATCTACGGTTAT
  GAAGGCAGGGGCTCAGTGGCCGGGTCCCTGAGCTCCCTAGAGTCGGCCACCACAGATTCA
  GACTTGGACTATGATTATCTACAGAACTGGGGACCTCGTTTTAAGAAACTAGCAGATTTG
  TATGGTTCCAAAGACACTTTTGATGACGATTCTTAACAATAACGATACAAATTTGGCCTT
  AAGAACTGTGTCTGGCGTTCTCAAGAATCTAGAAGATGTGTAAACAGGTATTTTTTTAAA
  TCAAGGAAAGGCTCATTTAAAACAGGCAAAGTTTTACAGAGAGGATACATTTAATAAAAC
  TGCGAGGACATCAAAGTGGTAAATACTGTGAAATACCTTTTCTCACAAAAAGGCAAATAT
  TGAAGTTGTTTATCAACTTCGCTAGAAAAAAAAAACACTTGGCATACAAAATATTTAAGT
  GAAGGAGAAGTCTAACGCTGAACTGACAATGAAGGGAAATTGTTTATGTGTTATGAACAT
  CCAAGTCTTTCTTCTTTTTTAAGTTGTCAAAGAAGCTTCCACAAAATTAGAAAGGACAAC
  AGTTCTGAGCTGTAATTTCGCCTTAAACTCTGGACACTCTATATGTAGTGCATTTTTAAA
  CTTGAAATATATAATATTCAGCCAGCTTAAACCCATACAATGTATGTACAATACAATGTA
  CAATTATGTCTCTTGAGCATCAATCTTGTTACTGCTGATTCTTGTAAATCTTTTTGCTTC
  TACTTTCATCTTAAACTAATACGTGCCAGATATAACTGTCTTGTTTCAGTGAGAGACGCC
  CTATTTCTATGTCATTTTTAATGTATCTATTTGTACAATTTTAAAGTTCTTATTTTAGTA
  TACATATAAATATCAGTATTCTGACATGTAAGAAAATGTTACGGCATCACACTTATATTT
  TATGAACATTGTACTGTTGCTTTAATATGAGCTTCAATATAAGAAGCAATCTTTGAAATA
  AAAAAAGATTTTTTTTTAAAAAAAAAAAAAAAAAACTCGAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001797 unedited
  CCTGAAATTTGATAATACCACTTTCTGATAGGGCGGCACACNACATCGCACGAGGGTCAA
  GAAAAATCGGGCGGGCAGGCCGAAGAGGAAATCACTGTGTTTTCAGCTCAGCGGCCCTGT
  GACATTCCTTCGTGTTGTCATTTGTTGAGTGACCAATCAGATGGGTGGAGTGTGTTACAG
  AAATTGGCAGCAAGTATCCAATGGGTGAAGAAGAAGCTTTCTGGGGACGTGGGCAGCCCT
  GACGTGATGAGCTCAACCAGCAGAGACATTCCATCCCAAGAGAGGTCTGCGTGACGCGTC
  CGGGAGGCCACCCTCAGCAAGACCACCGTACAGTTGGTGGAAGGGGTGACAGCTGCATTC
  TCCTGTGCCTACCACGTAACCAAAAATGAAGGAGAACTACTGTTTACAAGCCGCCCTGGT
  GTGCCTGGGCATGCTGTGCCACAGCCATGCCTTTGCCCCAGAGCGGCGGGGGCACCTGCG
  GCCTTCCTTCCATGGGCACCATGAGAAGGGCAAGGAGGGGCAGGTGCTACAGCGCTCCAA
  GCGTGGCTGGGTCTGGAACCAGTTCTTCGTGATAGAGGAGTACACCGGGCCTGACCCCGT
  GCTTGTGGGCAGGCTTCATTCAGATATTGACTCTGGTGATGGGAACATTAAATACATTCT
  CTCAGGNGAAGGAGCTGGAACCATTTTTGTGATTGATGAACAATCANGGAACATTCATGC
  CACCAAGACGTTGGATCGAGAAGAGAGAGCCCAGTACACGTTGATGGCTCANGCGGTGGA
  CAGGGACCCAATCGGCCACTGGAGCCACCGTNCGAATTCATTTGTCAGGTCCAGNACATT
  AATGACNACCCTCCGAAGTTTCTGCACGAGAACTATCATGCCNACGTTGCCTGAAAGGTC
  CATGTGGGAACGTCAGTAATCCAAGTGGAAGCCTCAGATA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001797 unedited
  GGCACGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTAAAAAAAATCTTTTTTTATTT
  CAAAGATTGCTTCTTATATTGAAGCTCATATTAAAGCAACAGTACAATGTTCATAAAATA
  TAAGTGTGATGCCGTAACATTTTCTTACATGTCATAATACTGATATTTATATGTATACTA
  AAATAAGAACTTTAAAATTGTACAAATAGATACATTAAAAATGACATAGAAATAGGGCGT
  CTCTCACTGAAACAAGACAGTTATATCTGCCACGTATTAGTTTAAGATGAAAGTACAAGC
  AAAAAGATTTACAAGAATCAGCAGTAACAAGATTGATGCTCAAGAGACATAATTGTACAT
  TGTATTGAACATACATTGTATGGGTTTAACCTGGCTGAATATTATTATATTGCAAGTTTA
  AAAATGCACTACATATACAGTGTTCAGAGCTTAACGCCAAATTACAGCTCACAACCTGCG
  CACTTTATAATAATGTGGAAACTTCTTTGCCACCTTATAATATATTAAAGATTTGCATGC
  CTGTTATCACTTCTCTTTTTCCTTCTTTGTCCCTCCATCCTCTATTTTATTCCTCCCTTT
  CATCTCATTCGTGGATTGCGGCTTCTTCTTTTCAACCTATGTCTTTATAATCTCTCTCCC
  CCTCCAATTCCCCCACCCGCTCCTTCTTCTATAACTCTCACTTTCTCCTATATATTTTTC
  CCCTCGCCTTTGTTTCTGAGTATCCATTCTCCCGACCCCATCTCGTTCTCTACTAACCTT
  TCATCCTTTCATACCGCACTCTCCTTATTTCCGTCCTCTTTCTCATCCCTCATCTTATTT
  TCCACTCTATTTTTCTATTCTCTCGTTTCTACCCCTCCCCCCCTCTTCTTTTTTTTATTT
  ATACTTCCCACCTACCCCTCGCCCCGACCAACCATTTCATTTTTCTTCTTTCTTATACCC
  ATTCACN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001797
• Insert Size: 3520 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001797.2, NP_001788.2
• RefSeq Size: 3654 bp
• RefSeq ORF: 2391 bp
• Locus ID: 1009
• Cytogenetics: 16q21
• Domains: Cadherin_C_term, CA
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: 'This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.