Calcitonin receptor (CALCR) (NM_001742) Human Untagged Clone

CAT#: SC119074

CALCR (untagged)-Human calcitonin receptor (CALCR), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CALCR
• Synonyms: CRT; CT-R; CTR; CTR1
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119074 sequence for NM_001742 edited (data generated by NextGen Sequencing)
  ATGAGGTTCACATTTACAAGCCGGTGCTTGGCACTGTTTCTTCTTCTAAATCACCCAACC
  CCAATTCTTCCTGCCTTTTCAAATCAAACCTATCCAACAATAGAGCCCAAGCCATTTCTT
  TACGTCGTAGGACGAAAGAAGATGATGGATGCACAGTACAAATGCTATGACCGAATGCAG
  CAGTTACCCGCATACCAAGGAGAAGGTCCATATTGCAATCGCACCTGGGATGGATGGCTG
  TGCTGGGATGACACACCGGCTGGAGTATTGTCCTATCAGTTCTGCCCAGATTATTTTCCG
  GATTTTGATCCATCAGAAAAGGTTACAAAATACTGTGATGAAAAAGGTGTTTGGTTTAAA
  CATCCTGAAAACAATCGAACCTGGTCCAACTATACTATGTGCAATGCTTTCACTCCTGAG
  AAACTGAAGAATGCATATGTTCTGTACTATTTGGCTATTGTGGGTCATTCTTTGTCAATT
  TTCACCCTAGTGATTTCCCTGGGGATTTTCGTGTTTTTCAGGAGCCTTGGCTGCCAAAGG
  GTAACCCTGCACAAGAACATGTTTCTTACTTACATTCTGAATTCTATGATTATCATCATC
  CACCTGGTTGAAGTAGTACCCAATGGAGAGCTCGTGCGAAGGGACCCGGTGAGCTGCAAG
  ATTTTGCATTTTTTCCACCAGTACATGATGGCCTGCAACTATTTCTGGATGCTCTGTGAA
  GGGATCTATCTTCATACACTCATTGTCGTGGCTGTGTTTACTGAGAAGCAACGCTTGCGG
  TGGTATTATCTCTTGGGCTGGGGGTTCCCGCTGGTGCCAACCACTATCCATGCTATTACC
  AGGGCCGTGTACTTCAATGACAACTGCTGGCTGAGTGTGGAAACCCATTTGCTTTACATA
  ATCCATGGACCTGTCATGGCGGCACTTGTGGTCAATTTCTTCTTTTTGCTCAACATTGTC
  CGGGTGCTTGTGACCAAAATGAGGGAAACCCATGAGGCGGAATCCCACATGTACCTGAAG
  GCTGTGAAGGCCACCATGATCCTTGTGCCCCTGCTGGGAATCCAGTTTGTCGTCTTTCCC
  TGGAGACCTTCCAACAAGATGCTTGGGAAGATATATGATTACGTGATGCACTCTCTGATT
  CATTTCCAGGGCTTCTTTGTTGCGACCATCTACTGCTTCTGCAACAATGAGGTCCAAACC
  ACCGTGAAGCGCCAATGGGCCCAATTCAAAATTCAGTGGAACCAGCGTTGGGGGAGGCGC
  CCCTCCAACCGCTCTGCTCGCGCTGCAGCCGCTGCTGCGGAGGCTGGCGACATCCCAATT
  TACATCTGCCATCAGGAGCCGAGGAATGAACCAGCCAACAACCAAGGCGAGGAGAGTGCT
  GAGATCATCCCTTTGAATATCATAGAGCAAGAGTCATCTGCTTGA
  
  Clone variation with respect to NM_001742.3
  1340 t=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001742 unedited
  CCCATTTTGTAATACGACTTCACTATAGGGCGGCCGCGATTCGGCACGAGGGGCTGCGCC
  GCGCGGCTGGCGGACCTTCCCGGGTTGGAGAAGTGCGCACGTCCGCACCTCACCCTGCGG
  CTGACATCTCCTGCCCAGGAGATGGGCGCTGAAGCTTGAGCGCCTGAGTCCCTGGAGCCA
  CACCTGCGAACACCCTTTGCTTCTATTGAGCTGTGCCCAGCCGCCCAGTGACAGAATTCC
  AGGACAAAGAGATCTTCAAAAACCAAAAATGAGGTTCACATTTACAAGCCGGTGCTTGGC
  ACTGTTTCTTCTTCTAAATCACCCAACCCCAATTCTTCCTGCCTTTTCAAATCAAACCTA
  TCCAACAATAGAGCCCAAGCCATTTCTTTACGTCGTAGGACGAAAGAAGATGATGGATGC
  ACAGTACAAATGCTATGACCGAATGCAGCAGTTACCCGCATACCAAGGAGAAGGTCCATA
  TTGCAATCGCACCTGGGATGGATGGCTGTGCTGGGATGACACACCGGCTGGAGTATTGTC
  CTATCAGTTCTGCCCAGATTATTTTCCGGATTTTGATCCATCAGANAAGGTTACAAAATA
  CTGTGATGAAAAAGGTGTTTGGTTTAAACATCCTGAANACAATCGAACCTGGTCCAACTA
  TACTATGTGCAAATGCTTCACTCCTGAGGAACTGAAGAATGCATATGTTCTGTACTATTT
  GGCTATTGTGGGTCATTCTTTGTCATTTTTCACCCTAGTGATTTTCCTGGGGATTTTCGT
  GTTTTTCAGGAGCCTGGGCTGCCANNAGGTAACCCTGCACAAGAACATGGTTTCTACTTA
  CATTCTGAAATCCTATGATATCATCATCCACCTGTTTGAAGTAATACCAATGGAAAGCTC
  GTGCCAAGGGACCCCGTGAGCTGCAGGATTTGCATTTTTTCACCAGTCCAGGAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001742 unedited
  CGGGGGAATATGAGTNCTCTGTCTTATTTTAACATATACACAAACATAAGCATTTCACAT
  AATTTGGGCAGAACTATGTGCAATTCTATAATAAGCTATTTTGTTTTCTTCAACCCCTAC
  TATATTAGCATAATAACATCTAAAATATTTTAGCAATATATTATCACATTTGTACCACAG
  CTGCCAGAAATACTCTGTTTTCCATGTTTGTAAACAAAAATAGAACAATACTACATAACA
  CTGTGATTGGAAAAATACCTTCTTTTCGATCCCCCCCTTACATTCAGTAAAGGAGACTTA
  AACTACTTTAGTATCCCAAATTCATTTTCTCTGTAGAAATATAATTAATTTTCTCTGGGT
  GCGCTAAATATGTAACCATAACAAATCAATTTATTATCTTTCCACAACTAAATCACTTCT
  GAAAGGCAGTGGCAAAATATGACATAGATGAGACTGGAGATTTGGAGGGTTTCAATGTAC
  CTCCTCATTTAGCATACAAATTAAATAATGGTAACTCTGATTACTGTTGCAAATTCACAA
  ATTAATTTCAGGTGCCAGTAACGATACTGGTTTATTCAGGATTTTCAGAAATCTTATACT
  GGGAAGTAAAGAGAGATATGATAATATAATACTGGATTTTAATGAGAAACGTTAAACCTG
  AATTGAGTTATGGTTAAATTTGGAGCAGTTAATTTTTTGCCCTCCTGTTTTGGTAATAAC
  CAAAACAAAGCGGTCAACGACAGTTTGATTTCCAATTAGGCCCTCCTGGATATTCCGGGG
  AAAGCCGTGAACTTTTTTAAGCCTTGAAGCTGGGGGGAAAGCATTAAGGGACTTTGGGGG
  GGCTTTTAATAGCAGGAGGAAGGATGTAACCTTACGGGTAGAAGCGCC
  
• Restriction Sites: Please inquire
• ACCN: NM_001742
• Insert Size: 3900 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001742.2, NP_001733.1
• RefSeq Size: 3470 bp
• RefSeq ORF: 1425 bp
• Locus ID: 799
• Cytogenetics: 7q21.3
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: 'This gene encodes a high affinity receptor for the peptide hormone calcitonin and belongs to a subfamily of seven transmembrane-spanning G protein-coupled receptors. The encoded protein is involved in maintaining calcium homeostasis and in regulating osteoclast-mediated bone resorption. Polymorphisms in this gene have been associated with variations in bone mineral density and onset of osteoporosis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]'
  Transcript Variant: This variant (2) differs in the 5' UTR and lacks an alternate in-frame exon in the 5' coding region, compared to variant 1. The encoded isoform (2) is shorter than isoform 1. Variants 2 and 3 encode the same isoform (2). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments.