IL13 receptor alpha 1 (IL13RA1) (NM_001560) Human Untagged Clone

CAT#: SC119133

IL13RA1 (untagged)-Human interleukin 13 receptor, alpha 1 (IL13RA1)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: IL13RA1
• Synonyms: CD213A1; CT19; IL-13Ra; NR4
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001560 edited
  ATGGAGTGGCCGGCGCGGCTCTGCGGGCTGTGGGCGCTGCTGCTCTGCGCCGGCGGCGGG
  GGCGGGGGCGGGGGCGCCGCGCCTACGGAAACTCAGCCACCTGTGACAAATTTGAGTGTC
  TCTGTTGAAAACCTCTGCACAGTAATATGGACATGGAATCCACCCGAGGGAGCCAGCTCA
  AATTGTAGTCTATGGTATTTTAGTCATTTTGGCGACAAACAAGATAAGAAAATAGCTCCG
  GAAACTCGTCGTTCAATAGAAGTACCCCTGAATGAGAGGATTTGTCTGCAAGTGGGGTCC
  CAGTGTAGCACCAATGAGAGTGAGAAGCCTAGCATTTTGGTTGAAAAATGCATCTCACCC
  CCAGAAGGTGATCCTGAGTCTGCTGTGACTGAGCTTCAATGCATTTGGCACAACCTGAGC
  TACATGAAGTGTTCTTGGCTCCCTGGAAGGAATACCCAGTCCCGACACTAACTATACTCT
  CTACTATTGGCACAGAAGCCTGGAAAAAATTCATCAATGTGAAAACATCTTTAGAGAAGG
  CCAATACTTTGGTTGTTCCTTTGATCTGACCAAAGTGAAGGATTCCAGTTTTGAACAACA
  CAGTGTCCAAATAATGGTCAAGGATAATGCAGGAAAAATTAAACCATCCTTCAATATAGT
  GCCTTTAACTTCCCGTGTGAAACCTGATCCTCCACATATTAAAAACCTCTCCTTCCACAA
  TGATGACCTATATGTGCAATGGGAGAATCCACAGAATTTTATTAGCAGATGCCTATTTTA
  TGAAGTAGAAGTCAATAACAGCCAAACTGAGACACATAATGTTTTCTACGTCCAAGAGGC
  TAAATGTGAGAATCCAGAATTTGAGAGAAATGTGGAGAATACATCTTGTTTCATGGTCCC
  TGGTGTTCTTCCTGATACTTTGAACACAGTCAGAATAAGAGTCAAAACAAATAAGTTATG
  CTATGAGGATGACAAACTCTGGAGTAATTGGAGCCAAGAAATGAGTATAGGTAAGAAGCG
  CAATTCCACACTCTACATAACCATGTTACTCATTGTTCCAGTCATCGTCGCAGGTGCAAT
  CATAGTACTCCTGCTTTACCTAAAAAGGCTCAAGATTATTATATTCCCTCCAATTCCTGA
  TCCTGGCAAGATTTTTAAAGAAATGTTTGGAGACCAGAATGATGATACTCTGCACTGGAA
  GAAGTACGACATCTATGAGAAGCAAACCAAGGAGGAAACCGACTCTGTAGTGCTGATAGA
  AAACCTGAAGAAAGCCTCTCAGTGA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001560 unedited
  GGAAACGGGGCAAATTTTGTATACGACTCATATAGGCGGCCGCGNAATTCGCACGAGGCC
  AAGGCTCCAGCCCGGCCGGGCTCCGAGGCGAGAGGCTGCATGGAGTGGCCGGCGCGGCTC
  TGCGGGCTGTGGGCGCTGCTGCTCTGCGCCGGCGGCGGGGGCGGGGGCGGGGGCGCCGCG
  CCTACGGAAACTCAGCCACCTGTGACAAATTTGAGTGTCTCTGTTGAAAACCTCTGCACA
  GTAATATGGACATGGAATCCACCCGAGGGAGCCAGCTCAAATTGTAGTCTATGGTATTTT
  AGTCATTTTGGCGACAAACAAGATAAGAAAATAGCTCCGGAAACTCGTCGTTCAATAGAA
  GTACCCCTGAATGAGAGGATTTGTCTGCAAGTGGGGTCCCAGTGTAGCACCAATGAGAGT
  GAGAAGCCTAGCATTTTGGTTGAAAAATGCATCTCACCCCCAGAAGGTGATCCTGAGTCT
  GCTGTGACTGAGCTTCAATGCATTTGGCACAACCTGAGCTACATGAAGTGTTCTTGGCTC
  CCTGGAAGGAATACCAGTCCCGACACTAACTATACTCTCTACTATTGGCACAGAAGCCTG
  GAAAAAATTCATCAATGTGAAAACATCTTTAGAGAAGGCCAATACTTTGGTTGTTCCTTT
  GATCTGACCAAAGTGAAGGATTCCAGTTTTGAACAACACAGTGTCCAAATAATGGTCAAG
  GATAATGCANGAAAAATTAAACCATCCTTCAATATAGTGCCTTTAACTTCCCGTGTGAAA
  CCTGATCCTCCACATATTAAAAACCTCTCCTTCCACAATGATGACCTATATGTGCAATGG
  GGAGATCCACAGAATTTTATTAGCAGATGCCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001560 unedited
  CGCAATCTAGTATCGAGTTTTTTTTTTTTTTTTTTGACATACAAAAAGACAATATTTATT
  TTACTCAAGCTTTCCTATAAGAAGTTAAACAGAAACAATCCCTGGTTGAAGACTACCAAA
  AATGTTAACATTGTTTCACATATCCCTTCAGTGCCCAGATGAAGGGAAAAACTTAACTGA
  ACGAAAGAATAAGAATTACCATCCTGACACTGGGTTTGCTTAAGTATGTTAGGAAAAAAT
  CCACATAGGCTAGACCTAAAACAGTAAATGAGCCTACTAATTTCCCACAGGGGATGGGAA
  ATCCACTGATACAGACACCTCCAAGAGCTCCCAAGACCTAGGGATCACAACCACCACAGG
  TATTCCCATAACTTCCTTTTCCCTCCCTTTTCCCTCAGCTATTTTACTGCTAAAAGAAGA
  GGATGGGAACAAAAGATCACTTCCCCACTCCCAGACTGCATGACTGTCAGCATCAATGTT
  TGTTGGGAATTTCACAGCATCCTCTTCATGGCCATCTAAATAGGATAACAGTAAAAATGG
  CTAGGGGGAGGCATGGGTTTTGCTTCCCAGAATTATAAAATACCTGGAAAGGAATTAATC
  TCATTCCTATACAGGAAAACCAAATATTCTTTCTAGAGAACAGCAGAACAAAGTAGAACA
  TCTACTACGGCTGTCTCCCAGCCTCAATCTGACTTCAAGAATAACTTTACATCTGCCATT
  GTCATGAACCCCAGCTTCCTCAGAGAAGCCAGGGCACCATGCTTCTACACGGNCATGGAA
  GCATGNTGCCACTTNGTACCAAACCTGTAGAGAGTGAGGTTCTTATCTNCCCTCCCCTAG
  AGCAGATTGCAATAGCTCATGGACTATATGATTGGNAAGCTTGACACCTGAAATAAGTCT
  CAAGTTCTACAGTATATGATCTGGTGTGAGGAAGAATGGGCGGGGNAATGCTCTCATTCC
  ATCTNCTTANTNGNGGNATAGAGTNAGGGATTTN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001560
• Insert Size: 4000 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001560.2, NP_001551.1
• RefSeq Size: 4006 bp
• RefSeq ORF: 1284 bp
• Locus ID: 3597
• Cytogenetics: Xq24
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• Gene Summary: 'The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4. [provided by RefSeq, Jul 2008]'