Aryl hydrocarbon Receptor (AHR) (NM_001621) Human Untagged Clone

CAT#: SC119159

AHR (untagged)-Human aryl hydrocarbon receptor (AHR)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: AHR
• Synonyms: bHLHe76; RP85
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF sequence for NM_001621 edited
  GGGCGGCCGCGAATTCTGCACCAGGGGAGGCAGTGGCTGGGGAGTCCCGTCGACGCTCTG
  TTCCGAGAGCGTGCCCCGGACCGCCAGCTCAGAACAGGGGCAGCCGTGTAGCCGAACGGA
  AGCTGGGAGCAGCCGGGACTGGTGGCCCGCGCCCGAGCTCCGCAGGCGGGAAGCACCCTG
  GATTTAGGAAGTCCCGGGAGCAGCGCGGCGGCACCTCCCTCACCCAAGGGGCCGCGGCGA
  CGGTCACGGGGCGCGGCGCCACCGTGAGCGACCCAGGCCAGGATTCTAAATAGACGGCCC
  AGGCTCCTCCTCCGCCCGGGCCGCCTCACCTGCGGGCATTGCCGCGCCGCCTCCGCCGGT
  GTAGACGGCACCTGCGCCGCCTTGCTCGCGGGTCTCCGCCCCTCGCCCACCCTCACTGCG
  CCAGGCCCAGGCAGCTCACCTGTACTGGCGCGGGCTGCGGAAGCCTGCGTGAGCCGAGGC
  GTTGAGGCGCGGCGCCCACGCCACTGTCCCGAGAGGACGCAGGTGGAGCGGGCGCGGCTT
  CGCGGAACCCGGCGCCGGCCGCCGCAGTGGTCCCAGCCTACACCGGGTTCCGGGGACCCG
  GCCGCCAGTGCCCGGGGAGTAGCCGCCGCCGTCGGCTGGGCACCATGAACAGCAGCAGCG
  CCAACATCACCTACGCCAGTCGCAAGCGGCGGAAGCCGGTGCAGAAAACAGTAAAGCCAA
  TCCCAGCTGAAGGAATCAAGTCAAATCCTTCCAAGCGGCATAGAGACCGACTTAATACAG
  AGTTGGACCGTTTGGCTAGCCTGCTGCCTTTCCCACAAGATGTTATTAATAAGTTGGACA
  AACTTTCAGTTCTTAGGCTCAGCGTCAGTTACCTGAGAGCCAAGAGCTTCTTTGATGTTG
  CATTAAAATCCTCCCCTACTGAAAGAAACGGAGGCCAGGATAACTGTAGAGCAGCAAATT
  TCAGAGAAGGCCTGAACTTACAAGAAGGAGAATTCTTATTACAGGCTCTGAATGGCTTTG
  TATTAGTTGTCACTACAGATGCTTTGGTCTTTTATGCTTCTTCTACTATACAAGATTATC
  TAGGGTTTCAGCAGTCTGATGTCATACATCAGAGTGTATATGAACTTATCCATACCGAAG
  ACCGAGCTGAATTTCAGCGTCAGCTACACTGGGCATTAAATCCTTCTCAGTGTACAGAGT
  CTGGACAAGGAATTGAAGAAGCCACTGGTCTCCCCCAGACAGTAGTCTGTTATAACCCAG
  ACCAGATTCCTCCAGAAAACTCTCCTTTAATGGAGAGGTGCTTCATATGTCGTCTAAGGT
  GTCTGCTGGATAATTCATCTGGTTTTCTGGCAATGAATTTCCAAGGGAAGTTAAAGTATC
  TTCATGGACAGAAAAAGAAAGGGAAAGATGGATCAATACTTCCACCTCAGTTGGCTTTGT
  TTGCGATAGCTACTCCACTTCAGCCACCATCCATACTTGAAATCCGGACCAAAAATTTTA
  TCTTTAGAACCAAACACAAACTAGACTTCACACCTATTGGTTGTGATGCCAAAGGAAGAA
  TTGTTTTAGGATATACTGAAGCAGAGCTGTGCACGAGAGGCTCAGGTTATCAGTTTATTC
  ATGCAGCTGATATGCTTTATTGTGCCGAGTCCCATATCCGAATGATTAAGACTGGAGAAA
  GTGGCATGATAGTTTTCCGGCTTCTTACAAAAAACAACCGATGGACTTGGGTCCAGTCTA
  ATGCACGCCTGCTTTATAAAAATGGAAGACCAGATTATATCATTGTAACTCAGAGACCAC
  TAACAGATGAGGAAGGAACAGAGCATTTACGAAAACGAAATACGAAGTTGCCTTTTATGT
  TTACCACTGGAGAAGCTGTGTTGTATGAGGCAACCAACCCTTTTCCTGCCATAATGGATC
  CCTTACCACTAAGGACTAAAAATGGCACTAGTGGAAAAGACTCTGCTACCACATCCACTC
  TAAGCAAGGACTCTCTCAATCCTAGTTCCCTCCTGGCTGCCATGATGCAACAAGATGAGT
  CTATTTATCTCTATCCTGCTTCAAGTACTTCAAGTACTGCACCTTTTGAAAACAACTTTT
  TCAACGAATCTATGAATGAATGCAGAAATTGGCAAGATAATACTGCACCGATGGGAAATG
  ATACTATCCTGAAACATGAGCAAATTGACCAGCCTCAGGATGTGAACTCATTTGCTGGAG
  GTCACCCAGGGCTCTTTCAAGATAGTAAAAACAGTGACTTGTACAGCATAATGAAAAACC
  TAGGCATTGATTTTGAAGACATCAGACACATGCAGAATGAAAAATTTTTCAGAAATGATT
  TTTCTGGTGAGGTTGACTTCAGAGACATTGACTTAACGGATGAAATCCTGACGTATGTCC
  AAGATTCTTTAAGTAAGTCTCCCTTCATACCTTCAGATTATCAACAGCAACAGTCCTTGG
  CTCTGAACTCAAGCTGTATGGTACAGGAACACCTACATCTAGAACAGCAACAGCAACATC
  ACCAAAAGCAAGTAGTAGTGGAGCCACAGCAACAGCTGTGTCAGAAGATGAAGCACATGC
  AAGTTAATGGCATGTTTGAAAATTGGAACTCTAACCAATTCGTGCCTTTCAATTGTCCAC
  AGCAAGACCCACAACAATATAATGTCTTTACAGACTTACATGGGATCAGTCAAGAGTTCC
  CCTACAAATCTGAAATGGATTCTATGCCTTATACACAGAACTTTATTTCCTGTAATCAGC
  CTGTATTACCACAACATTCCAAATGTACAGAGCTGGACTACCCTATGGGGAGTTTTGAAC
  CATCCCCATACCCCACTACTTCTAGTTTAGAAGATTTTGTCACTTGTTTACAACTTCCTG
  AAAACCAAAAGCATGGATTAAATCCACAGTCAGCCATAATAACTCCTCAGACATGTTATG
  CTGGGGCCGTGTCGATGTATCAGTGCCAGCCAGAACCTCAGCACACCCACGTGGGTCAGA
  TGCAGTACAATCCAGTACTGCCAGGCCAACAGGCATTTTTAAACAAGTTTCAGAATGGAG
  TTTTAAATGAAACATATCCAGCTGAATTAAATAACATAAATAACACTCAGACTACCACAC
  ATCTTCAGCCACTTCATCATCCGTCAGAAGCCAGACCTTTTCCTGATTTGACATCCAGTG
  GATTCCTGTAATTCCAAGCCCAATTTTGACCCTGGTTTTTGGATTAAATTAGTTTGTGAA
  GGATTATGGAAAAATAAAACTGTCACTGTTGGACGTCAGCAAGTTCACATGGAGGCATTG
  ATGCATGCTATTCACAATTATTCCAAACCAAATTTTAATTTTTGCTTTTAGAAAAGGGAG
  TTTAAAAATGGTATCAAAATTACATATACTACAGTCAAGATAGAAAGGGTGCTGCCACGG
  AGTGGTGAGGTACCGTCTACATTTCACATTATTCTGGGCACCACAAAATATACAAAACTT
  TATCAGGGAAACTAAGATTCTTTTAAATTAGAAAATATTCTCTATTTGAATTATTTCTGT
  CACAGTAAAAATAAAATACTTTGAGTTTTGAGCTACTGGATTCTTATTAGTTCCCCAAAT
  ACAAAGTTAGAGAACTAAACTAGTTTTTCCTATCATGTTAACCTCTGCTTTTATCTCAGA
  TGTTAAAATAAATGGTTTGGTGCTTTTTATAAAAAGATAATCTCAGTGCTTTCCTCCTTC
  ACTGTTTCATCTAAGTGCCTCACATTTTTTTCTACCTATAACACTCTAGGATGTATATTT
  TATATAAAGTATTCTTTTT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001621 unedited
  NNGTGTCGGAATTTGTATACGACTCCTATAGGCGGCCCGCGATTCGGCACCAGGGGAGGC
  AGTGGCTGGGGAGTCCCGTCGACGCTCTGTTCCGAGAGCGTGCCCCGGACCGCCAGCTCA
  GACAGGGGCAGCCGTGTAGCCGAACGGAAGCTGGGAGCAGCCGGGACTGGTGGCCCGCGC
  CCGAGCTCCGCAGGCGGGAAGCACCCTGGATTTAGGAAGTCCCGGGAGCAGCGCGGCGGC
  ACCTCCCTCACCCAAGGGGCCGCGGCGACGGTCACGGGGCGCGGCGCCACCGTGAGCGAC
  CCAGGCCAGGATTCTAAATAGACGGCCCAGGCTCCTCCTCCGCCCGGGCCGCCTCACCTG
  CGGGCATTGCCGCGCCGCCTCCGCCGGTGTAGACGGCACCTGCGCCGCCTTGCTCGCGGG
  TCTCCGCCCCTCGCCCACCCTCACTGCGCCAGGCCCAGGCAGCTCACCTGTACTGGCGCG
  GGCTGCGGAAGCCTGCGTGAGCCGAGGCGTTGAGGCGCGGCGCCCACGCCACTGTCCCGA
  GAGGACGCAGGTGGAGCGGGCGCGGCTTCGCGGAACCCGGCGCCGGCCGCCGCAGTGGTC
  CCAGCCTACACCGGGTTCCGGGGACCCGGCCGCCAGTGCCCGGNGAGTAGCCGCCGCCGT
  CGGCTGGGCACCATGAACAGCAGCAGCGCCAACATCACCTACGCCAGTCGCAAGCGGCGG
  AAGCCGGTGCAGAANACAGTAAAGCCAATCCCAGCTGAAGGAATCAAGTCAAATCCTTCC
  AAGCGGCATAGAGACCCGACTTATACAGAGNTGGACCGTTTGGCTAGCCTGCTGCCTTTC
  CCACAGATGTATTAATAAGTGGACANACTTCAGTTCTAAGCTCAGCGTCATTACCTGAGA
  GCCAGAC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001621 unedited
  NAACCCTACGTGNTATTTTTATTCTTTANTACATTTTAGTTATTTTATATAGATAAAATA
  TACAATATTGCTTTTCAAACTTTTAATTTTATAACTGTATAACTGATTGTCATCATATTC
  ATGATTAAAAAGCCTATTTTCCACTAAACAATTTATCCAGTAACATGTGGAAGAGAGTAA
  CAAAAATGGTTTATGTAAGACTTATAATAAAAGGTTTAAATGTAAAAATAGAGTATTAAT
  CTAGACCTCTGGTCTAAATCCTTAGATACCTCATGCTGGAAACAAATTATGAAATGTTTC
  AGACAAATTTTTTCCAACACTTAAATTGATTCTACAGGTTTAAAGTTTTGACTGAAAATA
  CACAGAACTCAGAGATATTTTGTCCGAAGCCATTTTTATATACATTAACTTACTAAAAAA
  AGTAAAAGAAATAAAAATTGTATTTTTTTTTTTTTTGGAGACGGAGTCTCGGTCTATTGC
  CAGGCTGGAGTGCAGTGGGGCGATCTTGGCTCTGCAACCTCCGATTCCCAGGTTCAGGCT
  ATTCTCCTGCCTCAGCCTCCCGAGTAGCTAGGACCACAGGCTCACGCCACCATGCCTGGT
  ATCCCAGCAACCTCGGAGGCTTTGGCCTGAGAATTACCTGAACCCAGGAAGGTGAGGGTG
  CCCTGGCCCCCCCTGGGGCTCCCGCCCCCCCTTTCCGGCGGCCTTGGTTGCCCCCTTTCC
  TCCTCCTCGTCTCCCTCTGCTCCCTGGCCGGGCGCTCTCTCGCTTTCCCCCCTCCTCTCC
  CTCCTCTTCGGCGGGCGTCTCTTCTTCTTCTGTCGCCGNCCCTCCCTTTTTCTCTCTTCT
  TTCCTCTCCTTCTTTTGCCTTTTCTCTGGGGTGGCCGCCCCCGGTCCCCCCTGAACACAA
  GAAAAAA
  
• Restriction Sites: NotI-NotI
• ACCN: NM_001621
• Insert Size: 5000 bp
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001621.2, NP_001612.1
• RefSeq Size: 5496 bp
• RefSeq ORF: 2547 bp
• Locus ID: 196
• Cytogenetics: 7p21.1
• Domains: PAS, HLH, PAC
• Protein Families: Druggable Genome, Nuclear Hormone Receptor, Transcription Factors
• Gene Summary: 'The protein encoded by this gene is a ligand-activated helix-loop-helix transcription factor involved in the regulation of biological responses to planar aromatic hydrocarbons. This receptor has been shown to regulate xenobiotic-metabolizing enzymes such as cytochrome P450. Before ligand binding, the encoded protein is sequestered in the cytoplasm; upon ligand binding, this protein moves to the nucleus and stimulates transcription of target genes. [provided by RefSeq, Sep 2015]'