CD27 (NM_001242) Human Untagged Clone

CAT#: SC119371

CD27 (untagged)-Human CD27 molecule (CD27)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CD27
• Synonyms: S152; S152. LPFS2; T14; TNFRSF7; Tp55
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_001242 edited
  GTGGAGGTTGCTGCTATGAGAGAGAAAAAAAAAAACAGCCACAATAGAGATTCTGCCTTC
  AAAGGTTGGCTTGCCACCTGAAGCAGCCACTGCCCAGGGGGTGCAAAGAAGAGACAGCAG
  CGCCCAGCTTGGAGGTGCTAACTCCAGAGGCCAGCATCAGCAACTGGGCACAGAAAGGAG
  CCGCCTGGGCAGGGACCATGGCACGGCCACATCCCTGGTGGCTGTGCGTTCTGGGGACCC
  TGGTGGGGCTCTCAGCTACTCCAGCCCCCAAGAGCTGCCCAGAGAGGCACTACTGGGCTC
  AGGGAAAGCTGTGCTGCCAGATGTGTGAGCCAGGAACATTCCTCGTGAAGGACTGTGACC
  AGCATAGAAAGGCTGCTCAGTGTGATCCTTGCATACCGGGGGTCTCCTTCTCTCCTGACC
  ACCACACCCGGCCCCACTGTGAGAGCTGTCGGCACTGTAACTCTGGTCTTCTCGTTCGCA
  ACTGCACCATCACTGCCAATGCTGAGTGTGCCTGTCGCAATGGCTGGCAGTGCAGGGACA
  AGGAGTGCACCGAGTGTGATCCTCTTCCAAACCCTTCGCTGACCGCTCGGTCGTCTCAGG
  CCCTGAGCCCACACCCTCAGCCCACCCACTTACCTTATGTCAGTGAGATGCTGGAGGCCA
  GGACAGCTGGGCACATGCAGACTCTGGCTGACTTCAGGCAGCTGCCTGCCCGGACTCTCT
  CTACCCACTGGCCACCCCAAAGATCCCTGTGCAGCTCCGATTTTATTCGCATCCTTGTGA
  TCTTCTCTGGAATGTTCCTTGTTTTCACCCTGGCCGGGGCCCTGTTCCTCCATCAACGAA
  GGAAATATAGATCAAACAAAGGAGAAAGTCCTGTGGAGCCTGCAGAGCCTTGTCGTTACA
  GCTGCCCCAGGGAGGAGGAGGGCAGCACCATCCCCATCCAGGAGGATTACCGAAAACCGG
  AGCCTGCCTGCTCCCCCTGAGCCAGCACCTGCGGTAGCTGCACTACAGCCCTGGCCTCCA
  CCCCCACCCCGCCGACCATCCAAGGGAGAGTGAGACCTGGCAGCCACAACTGCAGTCCCA
  TCCTCTTGTCAGGGCCCTTTCCTGTGTACACGTGACAGAGTGCCTTTTCGAGACTGGCAG
  GGACGAGGACAAATATGGATGAGGTGGAGAGTGGGAAGCAGGAGCCCAGCCAGCTGCGCC
  TGCGCTGCAGGAGGGCGGGGGCTCTGGTTGTAAAACACACTTCCTGCTGCGAAAGACCCA
  CATGCTACAAGACGGGCAAAATAAAGTGACAGATGACCACCCTGCAAAAAAAAAAAAAAA
  AAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_001242 unedited
  GGCACTACTGGTTTTTGTAAACCCGATTCAGCTATAGGCGGCCGCGCATTCGGCACGAGG
  GTGGAGGTTGCTGCTATGAGAGAGAAAAAAAAAAACAGCCACAATAGAGATTCTGCCTTC
  AAAGTTGGCTTGCCACCTGAAGCAGCCACTGCCCAGGGGGTGCAAAGAAGAGACAGCAGC
  GCCCAGCTTGGAGGTGCTAACTCCAGAGGCCAGCATCAGCAACTGGGCACAGAAAGGAGC
  CGCCTGGGCAGGGACCATGGCACGGCCACATCCCTGGTGGCTGTGCGTTCTGGGGACCCT
  GGTGGGGCTCTCAGCTACTCCAGCCCCCAAGAGCTGCCCAGAGAGGCACTACTGGGCTCA
  GGGAAAGCTGTGCTGCCAGATGTGTGAGCCAGGAACATTCCTCGTGAAGGACTGTGACCA
  GCATAGAAAGGCTGCTCAGTGTGATCCTTGCATACCGGGGGTCTCCTTCTCTCCTGACCA
  CCACACCCGGCCCCACTGTGAGAGCTGTCGGCACTGTAACTCTGGTCTTCTCGTTCGCAA
  CTGCACCATCACTGCCAATGCTGAGTGTGCCTGTCGCAATGGCTGGCAGTGCAGGGACAA
  GGAGTGCACCGAGTGTGATCCTCTTCCAAACCCTTCGCTGACCGCTCGGTCGTCTCAGGC
  CCTGAGCCCACACCCTCAGCCCACCCACTTACCTTATGTCAGTGAGATGCTGGAGGCCAG
  GACAGCTGGGCACATGCAGACTCTGGCTGACTTCAGGCAGCTGCCTGCCCGGACTCTCTC
  TACCCACTGGCCACCCCAAAGATCCCTGTGCAGCTCCGATTCTATTCGCATCCTTGTGAT
  CTTCTCTGGAATGTTCCTTGTTTTCACCCTGGCCGGNGCCCTGTTNCTNCATCACGAAGG
  AATATAGATCAAACAAGGAGA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_001242 unedited
  CCATGGCACCATTGGGCGATTGGCAACTTGCCAGGGCCAGNAAAGCACTGGGGNAGGGTC
  ACAGGGCAGCCACCCGGGTATCTGTTCAGGAAAACAGCTATGACCGCGGCCGCAATCTAG
  AGTCGAGTTTTTTTTTTTTTTTTTTGCAGGGTGGTCATCTGTCACTTTATTTTGCCCGTC
  TTGTAGCATGTGGGTCTTTCGCAACAGGAAGTGTGTTTTACAACCAGAGCCCCCGCCCTC
  CTGCAGCGCAAGCGCAGCTGGCTGGGCTCCTGCTTCCCACTCTCCACCTCATCCATATTT
  GTCCTCGTCCCTGCCAGTCTCGAAAAGGCACTCTGTCACGTGTACACAGGAAAGGGCCCT
  GACAAGAGGATGGGACTGCAGTTGTGGCTGCCAGGTCTCACTCTCCCTTGGATGGTCCGC
  GGGGTGGNGGGTTGGACGCCAGGGCTGTAGTGCATCTACCGCAGGTGCTGGCTCAAGGGG
  AGCAGGCAGGCTCCGGTTTTCGGTAATCCTCCTGGATGGGAGATGGTGCTGCCCTCCTCC
  TCCCTGGGGCAGCTGTAACGACAAGGCTCTGCAGGCTCCACAGGACTTTCTCCTTTGTTT
  GATCTATATTTCCTTCGTTGATGGAAGAACAGGGCCCCGGCCAGGGTGAAAACAAGGAAC
  ATTCCAGAGAAGATCACAAGGATGCGAATAAAATCGGAGCTGCACAGGGATCTTTGGGGT
  GGCCAGTGGGTAGAGAGAGTCCGGGCAGGCAGCTGCCTGAAGTCAGCCAGAGTCTGCATG
  TGCCCAGCTGTCCTGGCCTCCAACATCTCACTGACATAAGGTAAGTGGGTGGGCTGAGGG
  TTGTGGGCTCCAGGCCTGAAACCACCGAGCGGTCAGCGAAGGGTTTGGAAAAGATCACAC
  TCGTGCACTTCTTGTGCCTGCACTGGCAG
  
• Restriction Sites: Please inquire
• ACCN: NM_001242
• Insert Size: 1323 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_001242.3, NP_001233.1
• RefSeq Size: 1323 bp
• RefSeq ORF: 783 bp
• Locus ID: 939
• Cytogenetics: 12p13.31
• Protein Families: Druggable Genome, Transmembrane
• Protein Pathways: Cytokine-cytokine receptor interaction
• Gene Summary: 'The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]'