Prostaglandin F2 alpha Receptor (PTGFR) (NM_000959) Human Untagged Clone

CAT#: SC119562

PTGFR (untagged)-Human prostaglandin F receptor (FP) (PTGFR), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTGFR
• Synonyms: FP
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119562 sequence for NM_000959 edited (data generated by NextGen Sequencing)
  ATGTCCATGAACAATTCCAAACAGCTAGTGTCTCCTGCAGCTGCGCTTCTTTCAAACACA
  ACCTGCCAGACGGAAAACCGGCTTTCCGTATTTTTTTCAGTAATCTTCATGACAGTGGGA
  ATCTTGTCAAACAGCCTTGCCATCGCCATTCTCATGAAGGCATATCAGAGATTTAGACAG
  AAGTCCAAGGCATCGTTTCTGCTTTTGGCCAGTGGCCTGGTAATCACTGATTTCTTTGGC
  CATCTCATCAATGGAGCCATAGCAGTATTTGTATATGCTTCTGATAAAGAATGGATCCGC
  TTTGACCAATCAAATGTCCTTTGCAGTATTTTTGGTATCTGCATGGTGTTTTCTGGTCTG
  TGCCCACTTCTTCTAGGCAGTGTGATGGCCATTGAGCGGTGTATTGGAGTCACAAAACCA
  ATATTTCATTCTACGAAAATTACATCCAAACATGTGAAAATGATGTTAAGTGGTGTGTGC
  TTGTTTGCTGTTTTCATAGCTTTGCTGCCCATCCTTGGACATCGAGACTATAAAATTCAG
  GCGTCGAGGACCTGGTGTTTCTACAACACAGAAGACATCAAAGACTGGGAAGATAGATTT
  TATCTTCTACTTTTTTCTTTTCTGGGGCTCTTAGCCCTTGGTGTTTCATTGTTGTGCAAT
  GCAATCACAGGAATTACACTTTTAAGAGTTAAATTTAAAAGTCAGCAGCACAGACAAGGC
  AGATCTCATCATTTGGAAATGGTAATCCAGCTCCTGGCGATAATGTGTGTCTCCTGTATT
  TGTTGGAGCCCATTTCTGGTTACAATGGCCAACATTGGAATAAATGGAAATCATTCTCTG
  GAAACCTGTGAAACAACACTTTTTGCTCTCCGAATGGCAACATGGAATCAAATCTTAGAT
  CCTTGGGTATATATTCTTCTACGAAAGGCTGTCCTTAAGAATCTCTATAAGCTTGCCAGT
  CAATGCTGTGGAGTGCATGTCATCAGCTTACATATTTGGGAGCTTAGTTCCATTAAAAAT
  TCCTTAAAGGTTGCTGCTATTTCTGAGTCACCAGTTGCAGAGAAATCAGCAAGCACCTAG
  
  Clone variation with respect to NM_000959.3
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000959 unedited
  AGTGCGCGGAGGGGACGAGCGGCTGGACCACAGCCGGCGCCCGATCAGGATCTCCGCGCT
  GGGATCGGTGGAACTTGAGGCAGCGGCGGCGCGGGGCGCCATGGCACACCGAGCGGCTCC
  GTCTTCTGCTCCTCAGAGAGCCCGGCTGGCGGCCTGGGATGACAAGATGTCTGGACTGCA
  ATCCTGCACAGTTTTGAGAGGGAGATGACTTGAGTGGTTGGCTTTTATCTCCACAACAAT
  GTCCATGAACAATTCCAAACAGCTAGTGTCTCCTGCAGCTGCGCTTCTTTCAAACACAAC
  CTGCCAGACGGAAAACCGGCTTTCCGTATTTTTTTCAGTAATCTTCATGACAGTGGGAAT
  CTTGTCAAACAGCCTTGCCATCGCCATTCTCATGAAGGCATATCAGAGATTTAGACAGAA
  GTCCAAGGGCATCGTTTCTGCTTTTGGCCAGGGGCCTGGTAATCACTGATTTCTTTGGCC
  ATCTCATCAATGGAGCCATAGCAGTATGTGTATATGCTTCTGATAAAGAATGGATCCGCT
  TTGACCAATCAAATGTCCCTTGCAGTATTTTTTGGGATCTGCATGGTGTTTTCTGGTCTG
  TGCCCACTTCTTCTAGGCAGGGGGATGGGCATTGAGCGGGGTATTGAAGTCCCAAAACCA
  TATTTCATTCTACAAAATTCCTCCAAACATGTGAAATGATGTTAAGGGGGTGTGCCTGTT
  GCCGGGTTAATAGCTTTGCTGGCCCTCCTTGGACCTCGAGACTTTAAATTCACGGCTGGA
  AGACCCNGGGGTTTTCCT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000959 unedited
  NTTTTAGCTNTGNNACCGCGGCCGCAATCTAGGATCGAGTTTTTTTTTTTTTTTTTTTTT
  TTTTTTTTTTTTTTTTAAACATTAGTCCCAACTTTATTATAAAATTACTTGTTTGAAGTT
  TTAAGCTAGTCAAAGCACTAAAATTACATGAGTTGCATACCAAAGCAAACAACAAAATAT
  ACATATCACTATTTAATCTCTATACAATCCAACAAGTATGAAGAGCACAACATACATTTA
  TTCACATAACCAAAAAAAACATGTTTCATCTACTATTAAAATGGGCCAGTAACAAGTTGA
  AGTCCAACATTATTTACCAGGGGGTAAAATCTTTGACACCCAGATTAAAAAGTAACAAAA
  TGTATATTCCCACCATTTATATTCTGACCCAAAACAGTTATTTAATTTGGAACAATGATG
  GTATACAGGGGAAGCTAGCAATAGTTTTAACAAAAAGCACATTCTATATTTAACAAGTCC
  TCTTATTTGGGTTCTAAACTCAAAGCAGGCACAAAACAAACCAGATTTCTCAAGCCCAAA
  AGGGGGCAAACAAGAAACATTTTTCACTTAACAAAATATATCCACCTATGGATGTACTAA
  CTTTCAGGGCTTTTTCGTTTTACCTTTATACATCCTTACAAATACCCTTTTGGCCCTAGG
  GAAAAAAAAAAAAGGCGCCATTTTTTGCGCGAGGTAACCCCTCCCCCAACGGCCCCCCTT
  TCTGCCCCACCCCCCGCCAATCGGCCACCTGGCCTTCTCCCTCGTCCGCAACGCGCAAAA
  ACCCTCTGGCGGAACCTCCGCGGCTTGTGGGGCCACTTTTTCACGAAAACAGGCCATGAG
  CCGTGCGAAAACCCTCAACTGCGGACGGTAGTGTGGGGCAACAATAACACGCGCGGAAAA
  GTTTGTTGAACCCCGCCGCGACCTT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000959
• Insert Size: 5310 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000959.2, NP_000950.1
• RefSeq Size: 3466 bp
• RefSeq ORF: 1080 bp
• Locus ID: 5737
• Cytogenetics: 1p31.1
• Domains: 7tm_1
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Calcium signaling pathway, Neuroactive ligand-receptor interaction
• Gene Summary: 'The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) encodes the longer isoform (a).