Protein C inhibitor (SERPINA5) (NM_000624) Human Untagged Clone

CAT#: SC119795

SERPINA5 (untagged)-Human serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 (SERPINA5)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: SERPINA5
• Synonyms: PAI-3; PAI3; PCI; PCI-B; PLANH3; PROCI
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC119795 sequence for NM_000624 edited (data generated by NextGen Sequencing)
  ATGCAGCTCTTCCTCCTCTTGTGCCTGGTGCTTCTCAGCCCTCAGGGGGCCTCCCTTCAC
  CGCCACCACCCCCGGGAGATGAAGAAGAGAGTCGAGGACCTCCATGTAGGTGCCACGGTG
  GCCCCCAGCAGCAGAAGGGACTTTACCTTTGACCTCTACAGGGCCTTGGCTTCCGCTGCC
  CCCAGCCAGAGCATCTTCTTCTCCCCTGTGAGCATCTCCATGAGCCTGGCCATGCTCTCC
  CTGGGGGCTGGGTCCAGCACAAAGATGCAGATCCTGGAGGGCCTGGGCCTAAACCTCCAG
  AAAAGCTCAGAGAAGGAGCTGCACAGAGGCTTTCAGCAGCTCCTTCAGGAACTCAACCAG
  CCCAGAGATGGCTTCCAGCTGAGCCTCGGCAATGCCCTTTTCACCGACCTGGTGGTAGAC
  CTGCAGGACACCTTCGTAAGTGCCATGAAGACGCTGTACCTGGCAGACACTTTCCCTACC
  AACTTTAGGGACTCTGCAGGGGCCATGAAGCAGATCAATGATTATGTGGCAAAGCAAACG
  AAGGGCAAGATTGTGGACTTGCTTAAGAACCTCGATAGCAATGCGGTCGTGATCATGGTG
  AATTACATCTTCTTTAAAGCTAAGTGGGAGACAAGCTTCAACCACAAAGGCACCCAAGAG
  CAAGACTTCTACGTGACCTCGCAGACTGTGGTGCGGGTACCCATGATGAGCCGCGAGGAT
  CAGTATCACTACCTCCTGGACCGGAACCTCTCCTGCAGGGTGGTGGGGGTCCCCTACCAA
  GGCAATGCCACGGCTTTGTTCATTCTCCCCAGTGAGGGAAAGATGCAGCAGGTGGAGAAT
  GGACTGAGTGAGAAAACGCTGAGGAAGTGGCTTAAGATGTTCAAAAAGAGGCAGCTCGAG
  CTTTACCTTCCCAAATTCTCCATTGAGGGCTCCTATCAGCTGGAGAAAGTCCTCCCCAGT
  CTGGGGATCAGTAACGTCTTCACCTCCCATGCTGATCTGTCCGGCATCAGCAACCACTCA
  AATATCCAGGTGTCTGAGATGGTGCACAAAGCTGTGGTGGAGGTGGACGAGTCGGGAACC
  AGAGCAGCGGCAGCCACGGGGACAATATTCACTTTCAGGTCGGCCCGCCTGAACTCTCAG
  AGGCTAGTGTTCAACAGGCCCTTTCTGATGTTCATTGTGGATAACAACATCCTCTTCCTT
  GGCAAAGTGAACCGCCCCTGA
  
  Clone variation with respect to NM_000624.4
  291 c=>a;682 g=>c
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000624 unedited
  AATTTGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGGCTGCCACCTCCA
  CTGTGTGCACACTCAGCTACGGGACACATTTCAGGTATCCAAGGCAGCAGAGGTGAGTGG
  GTCCCCCGAGCTCTGTGACCTTATGCTCCACACTAACTCTGGCAGAGCCTCCGTTTCCTC
  ATAGAACAAAGAACAGCCACCATGCAGCTCTTCCTCCTCTTGTGCCTGGTGCTTCTCAGC
  CCTCAGGGGGCCTCCCTTCACCGCCACCACCCCCGGGAGATGAAGAAGAGAGTCGAGGAC
  CTCCATGTAGGTGCCACGGTGGCCCCCAGCAGCAGAAGGGACTTTACCTTTGACCTCTAC
  AGGGCCTTGGCTTCCGCTGCCCCCAGCCAGAGCATCTTCTTCTCCCCTGTGAGCATCTCC
  ATGAGCCTGGCCATGCTCTCCCTGGGGGCTGGGTCCAGCACAAAGATGCAGATCCTGGAG
  GGCCTGNGCCTAAACCTCCAGAAAAGCTCAGAGAAGGAGCTGCACAGAGGCTTTCAGCAG
  CTCCTTCAGGAACTCAACCAGCCCAGAGATGGCTTCCAGCTGAGCCTCGGCAATGCCCTT
  TTCACCGACCTGGTGGTAGACCTGCAGGACACCTTCGTAAGTGCCATGAAGACGCTGTAC
  CTGGCAGACACTTTCCCTACCAACTTTAGGGACTCTGCAGGGGCCATGAAGCAGATCAAT
  GATTATGTGGCANAGCANACGAAGGGCAAGATTGTGGACTTGCTTAAGAACCTCGATAGC
  ATGCGGNCGTGATCATGGNGGATTACATCTTCCTTAAAGCTAAGTGGGAGACAGCTCCAC
  CCCAAAGCACCCAGAGCAGACTTCTACGTGACCTCCAGATGTGGTGCCGGTACCCATGAG
  G
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000624 unedited
  CCCCCCGGCCCACTTCTTCCCCCCCCCCCCCCCTTGGGGGGAAGAAACCTTGTTTATGCC
  AACTAGNAATCACAAGTTAGTCATTGGCACCTGCAACTGATACTCTACTATTTGCAAAAG
  GCTTCCCTTCTTCCACTCCCAGCCAGGCCCATCAGATTATAACTATATCCACAAAATGAT
  ATAATCAATCATTAAATGGGCCATTTCCACCTTGATATCCAGATGTTTTTCTTAAAGGAT
  GAATGGCACTTGAGTGTATTGAAATCAACCACGAATGACAGGGCCCACCCCAGCCTTTCT
  ATATGATTTCAGGAGTTCTTGGGTCACAGCAAGAATCTGATCCTTGTATACAGAGGGAAA
  CTGAGGTCCAGAGAGGGAAAGTGTTGTCCCAATGTCACACAGCACATTAGGACTGAAACA
  GTAGCCCCATTTCAGACTCCCATTCCAACATTTTTCCCATGCAGGATGAACTGACAGTTG
  TTGCTGCTGATAAGTGTGGGACCAGCCTTGGACCTGTGCTTCCTGGTGGCCCTCATCCAC
  TGGAACATCCCTCCTATTGAGCTTTGTGGCACTGAGCTGGGCATCAAGGGCCAGGACTCT
  GGACCTCTCTTTGCCACTACCATGCTGGTGAACTTGAGCAAGTCATCCAGCCTCTCTGGA
  TCTCAGNGTTAATCTTCATTGATGAATAGTGACCGCAAGATTGAATGTTCTCCACATTTT
  CCCCAGGCACCTGTATGTTGCACCCGTGTGGTTGGAAGCAATCATCATAGAGTAATATTA
  CTTGCCATGCCTCATTAATTAACTAAACCTGGGTAAATAACTAACTAACAGCATACAGAT
  GGCCCATAGCTTAACCCCCTTCATCTCCCAACCTGCAGCCTGTAGATTTAAAGAAAAACT
  CACCCTTAGGGGCGGGTCAATTTGGCAAGGCAGAAGATGTTGTTTTCCCACATGCACCAC
  CAAAAAGGGCCT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_000624
• Insert Size: 2400 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000624.3, NP_000615.2
• RefSeq Size: 2245 bp
• RefSeq ORF: 1221 bp
• Locus ID: 5104
• Cytogenetics: 14q32.13
• Domains: SERPIN
• Protein Families: Druggable Genome, Secreted Protein
• Protein Pathways: Complement and coagulation cascades
• Gene Summary: 'The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. This family member is a glycoprotein that can inhibit several serine proteases, including protein C and various plasminogen activators and kallikreins, and it thus plays diverse roles in hemostasis and thrombosis in multiple organs. [provided by RefSeq, Aug 2012]'