Aldehyde dehydrogenase 10 (ALDH3A2) (NM_000382) Human Untagged Clone

CAT#: SC119943

ALDH3A2 (untagged)-Human aldehyde dehydrogenase 3 family, member A2 (ALDH3A2), transcript variant 2


  "NM_000382" in other vectors (6)

Reconstitution Protocol

USD 820.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol ALDH3A2
Synonyms ALDH10; FALDH; SLS
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC119943 sequence for NM_000382 edited (data generated by NextGen Sequencing)
ATGGAGCTCGAAGTCCGGCGGGTCCGACAGGCGTTCCTGTCCGGCCGGTCGCGACCTCTG
CGGTTTCGGCTGCAGCAGCTGGAGGCCCTGCGGAGGATGGTGCAGGAGCGCGAGAAGGAT
ATCCTGACGGCCATCGCCGCCGACCTGTGCAAGAGTGAATTCAATGTGTACAGTCAGGAA
GTCATTACTGTCCTTGGGGAAATTGATTTTATGCTTGAGAATCTTCCTGAATGGGTTACT
GCTAAACCAGTTAAGAAGAACGTGCTCACCATGCTGGATGAGGCCTATATTCAGCCACAG
CCTCTGGGAGTGGTGCTGATAATCGGAGCTTGGAATTACCCCTTCGTTCTCACCATTCAG
CCACTGATAGGAGCCATCGCTGCAGGAAATGCTGTGATTATAAAGCCTTCTGAACTGAGT
GAAAATACAGCCAAGATCTTGGCAAAGCTTCTCCCTCAGTATTTAGACCAGGATCTCTAT
ATTGTTATTAATGGTGGTGTTGAGGAAACCACGGAGCTCCTGAAGCAGCGATTTGACCAC
ATTTTCTATACGGGAAACACTGCGGTTGGCAAAATTGTCATGGAAGCTGCTGCCAAGCAT
CTGACCCCTGTGACTCTTGAACTGGGAGGGAAAAGTCCATGTTATATTGATAAAGATTGT
GACCTGGACATTGTTTGCAGACGCATAACCTGGGGAAAATACATGAATTGTGGCCAAACC
TGCATTGCACCCGACTATATTCTCTGTGAAGCATCCCTCCAAAATCAAATTGTATGGAAG
ATTAAGGAAACAGTGAAGGAATTTTATGGAGAAAATATAAAAGAGTCTCCTGATTATGAA
AGGATCATCAATCTTCGTCATTTTAAGAGGATACTAAGTTTGCTTGAAGGACAAAAGATA
GCTTTTGGTGGGGAGACTGATGAGGCCACACGCTACATAGCCCCAACAGTACTTACCGAT
GTTGATCCTAAAACCAAGGTGATGCAAGAAGAAATTTTTGGACCAATTCTTCCAATAGTG
CCTGTGAAAAATGTAGATGAGGCCATAAATTTCATAAATGAACGTGAAAAGCCTCTGGCT
CTTTATGTATTTTCGCATAACCATAAGCTCATCAAACGGATGATTGATGAGACATCCAGT
GGAGGTGTCACAGGCAATGACGTCATTATGCACTTCACGCTCAACTCTTTCCCATTTGGA
GGAGTGGGTTCCAGTGGGATGGGAGCTTATCACGGAAAACATAGTTTTGATACTTTTTCT
CATCAGCGTCCCTGTTTATTAAAAAGTTTAAAGAGAGAAGGTGCTAACAAACTCAGATAT
CCTCCCAACAGCCAGTCAAAGGTGGATTGGGGAAAATTTTTTCTCTTGAAACGGTTCAAC
AAAGAAAAACTCGGTCTCCTGTTGCTCACTTTCCTGGGTATTGTAGCCGCTGTGCTTGTC
AAGGCTGAATATTACTGA

Clone variation with respect to NM_000382.2
1446 a=>t
>OriGene 5' read for NM_000382 unedited
NGGGTCATATTTGTATACGACTCCTATAGGGCGGCCGCGAATTCGCACCAGGCGGCTGAG
CGAGCGAGCCCTGGGCGAGTGAATTGTGGCTGTGGGTTGACGGTGGAGACACCCCCCGGA
GGGAGGCGGAGGGAAGGGAGGCGAGGCCTGCACCTGCATGCTTCCCGCCTCCCACTCCCC
AGCGCCCCCGGACCGTGCAGTTCTCTGCAGGACCAGGCCATGGAGCTCGAAGTCCGGCGG
GTCCGACAGGCGTTCCTGTCCGGCCGGTCGCGACCTCTGCGGTTTCGGCTGCAGCAGCTG
GAGGCCCTGCGGAGGATGGTGCAGGAGCGCGAGAAGGATATCCTGACGGCCATCGCCGCC
GACCTGTGCAAGAGTGAATTCAATGTGTACAGTCAGGAAGTCATTACTGTCCTTGGGGAA
ATTGATTTTATGCTTGAGAATCTTCCTGAATGGGTTACTGCTAAACCAGTTAAGAAGAAC
GTGCTCACCATGCTGGATGAGGCCTATATTCAGCCACAGCCTCTGGGAGTGGTGCTGATA
ATCGGAGCTTGGAATTACCCCTTCGTTCTCACCATTCAGCCACTGATAGGAGCCATCGCT
GCANGAAATGCTGTGATTATAAAGCCTTCTGAACTGAGTGAAAATACAGNCAAGGATCTT
GCAAAGCTTCTCCCTCAGTATTTAGACCAGGATCTCTATATTGTTATTAATGGNGGGTGG
TGGAGGGAACCACGGAAGCTCCTGAAGCACCGATTTGACCCCATTTTCTATACGGGAAAA
CCCTGCCGGTTGGCAAAATTGTCATGGAAACTTGCTTGCAAGCATCTGACCCCCGGGACT
CTTGACCTGGGAGGGAAAAATCCCTTGTTTTTTTGTTAAAGATT
>OriGene 3' read for NM_000382 unedited
CTTGGACGCGGCCGCAATCTANAATCGAGTTTTTTTTTTTTTTTTTTTTGATAAAGACAT
AAAATGATTTATAGTTGGGGAGAATTTATGATCAAAGGATTGTCTCCAATAGGGTATATC
TGAGGTTCCATACCAGGAGCGTCATTAAAATTGATGCCAATTTTATGAAATATGTTCATT
TTGAAGCAGATGTGTATTAGTAGACAAGCCAATAATTTAAACATACTCAATGAAAATTCC
ATAGTGCAATTTTATCTAAGGTATTTTATGATTACTCTCTTAGAGCCACAGTTTTAAGCA
GCTTTTTCCTAAACTAGGCTCGTTATTAATTTTCAACACTTCATACTATGATGAAGACAT
CACATACTTTAGACAGCCTTAATAGAACAAATTATTCAACAAAGTTGATTATACGTTCTA
TAAAGTAAATCACATTCTCTCATTGAGTGAGCTGAGTCTTTCTGAGTGTGGGGACAGAGT
CCCTGCAGTCAGGAGCTCCAAGGCATAGAACTGCCTGCCCTGCTCTGTCCAGCAGGTAAT
GCTGCATTCCACAGGCCTCTTCTTCAGCCTTGCCCACTCAGCAGAGTACCTCAGGTTGTG
ACCATGAACGACTGATGAGAGTAACTTCTGACTTGCTCAGGGGATCCTCTTGCCATCAAT
TCCCTTCAGTATGACCAACCGCAGTGGCTTACTCGCTTCTTGGCAGACCATCCACCATCT
GTCTGCCCATGATGCTCTCAAACCCAAAAGTCTAATATCCCAGCCCTCTTTGTCTGTGAG
AGGAAAGGGCTCCCTCACTTTAAGNTCTGTAGGGCTATCAGAAAGGGATCTCTCTATAGT
TTCAAAAGTGAAATTTACTTGGCCTACAGAAATAGAAACTACCGAATTGTTCTGGAAAAC
CACTACCTGCACCTTAAGGCCCTGAAGAGATAANATGTTATAATACTTTATACAGATTTT
TATTGTTTCGGAACGGGCCTGCCT
Restriction Sites NotI-NotI     
ACCN NM_000382
Insert Size 3370 bp
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_000382.2, NP_000373.1
RefSeq Size 3702 bp
RefSeq ORF 1458 bp
Locus ID 224
Cytogenetics 17p11.2
Domains aldedh
Protein Families Druggable Genome, Transmembrane
Protein Pathways Arginine and proline metabolism, Ascorbate and aldarate metabolism, beta-Alanine metabolism, Butanoate metabolism, Fatty acid metabolism, Glycerolipid metabolism, Glycolysis / Gluconeogenesis, Histidine metabolism, Limonene and pinene degradation, Lysine degradation, Metabolic pathways, Propanoate metabolism, Pyruvate metabolism, Tryptophan metabolism, Valine, leucine and isoleucine degradation
Gene Summary 'Aldehyde dehydrogenase isozymes are thought to play a major role in the detoxification of aldehydes generated by alcohol metabolism and lipid peroxidation. This gene product catalyzes the oxidation of long-chain aliphatic aldehydes to fatty acid. Mutations in the gene cause Sjogren-Larsson syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]'
Transcript Variant: This variant (2) lacks an alternate segment in the 3' coding region compared to variant 1. Isoform 2 has a shorter and different C-terminus, compared to isoform 1.

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