p19 INK4d (CDKN2D) (NM_079421) Human Untagged Clone

CAT#: SC120263

CDKN2D (untagged)-Human cyclin-dependent kinase inhibitor 2D (p19, inhibits CDK4) (CDKN2D), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: CDKN2D
• Synonyms: INK4D; p19; p19-INK4D
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC120263 sequence for NM_079421 edited (data generated by NextGen Sequencing)
  ATGCTGCTGGAGGAGGTTCGCGCCGGCGACCGGCTGAGTGGGGCGGCGGCCCGGGGCGAC
  GTGCAGGAGGTGCGCCGCCTTCTGCACCGCGAGCTGGTGCATCCCGACGCCCTCAACCGC
  TTCGGCAAGACGGCGCTGCAGGTCATGATGTTTGGCAGCACCGCCATCGCCCTGGAGCTG
  CTGAAGCAAGGTGCCAGCCCCAATGTCCAGGACACCTCCGGTACCAGTCCAGTCCATGAC
  GCAGCCCGCACTGGATTCCTGGACACCCTGAAGGTCCTAGTGGAGCACGGGGCTGATGTC
  AACGTGCCTGATGGCACCGGGGCACTTCCAATCCATCTGGCAGTTCAAGAGGGTCACACT
  GCTGTGGTCAGCTTTCTGGCAGCTGAATCTGATCTCCATCGCAGGGACGCCAGGGGTCTC
  ACACCCTTGGAGCTGGCACTGCAGAGAGGGGCTCAGGACCTCGTGGACATCCTGCAGGGC
  CACATGGTGGCCCCGCTGTGA
  
  Clone variation with respect to NM_079421.2
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_079421 unedited
  GGTCACCATTTGTATACGACTCACTATAGGCGGCCGCGAATCGGCACGAGGCCTCGTGCC
  GAATTCGGCACGAGGTCGACATGCTGCTGGAGGAGGTTCGCGCCGGCGACCGGCTGAGTG
  GGGCGGCGGCCCGGGGCGACGTGCAGGAGGTGCGCCGCCTTCTGCACCGCGAGCTGGTGC
  ATCCCGACGCCCTCAACCGCTTCGGCAAGACGGCGCTGCAGGTCATGATGTTTGGCAGCA
  CCGCCATCGCCCTGGAGCTGCTGAAGCAAGGTGCCAGCCCCAATGTCCAGGACACCTCCG
  GTACCAGTCCAGTCCATGACGCAGCCCGCACTGGATTCCTGGACACCCTGAAGGTCCTAG
  TGGAGCACGGGGCTGATGTCAACGTGCCTGATGGCACCGGGGCACTTCCAATCCATCTGG
  CAGTTCAAGAGGGTCACACTGCTGTGGTCAGCTTTCTGGCAGCTGAATCTGATCTCCATC
  GCAGGGACGCCAGGGGTCTCACACCCTTGGAGCTGGCACTGCAGAGAGGGGCTCAGGACC
  TCGTGGACATCCTGCAGGGCCACATGGTGGCCCCGCTGTGATCTGGGGTCACCCTCTCCA
  GCAAGAGAACCCCGTGGGGTTATGTATCAGAAGAGAGGGGAAGAAACACTTTCTCTTCTT
  GTTTCTCCTGCCCACTGCTGCAGTAGGGGAGGAGCACAGTTTGTGGCTTATAGGTGTTGG
  TTTGGGGGTGTGAGTGTTGGGGGGAACGTTTCTCATTTGTTTTTCTCACTCTTTTGGTGT
  GTTGACCAGAGAAGGCTCCTGCANGCCACAGCCCTACCGGGTTCANNTTCTCTGCGCCTC
  AGCTTGCTGGNGCCTCAGACAGACCCAAGGCAAGCATTTAANAATGAAGTCATGACTNCA
  GGAGCCTAAAGCTGTGG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_079421 unedited
  ATGGCCGCGGCCGCAATCTAGAGTCGAGTTTTTTTTTTTTTTTTTTGATCTGCACAAGTC
  TTAATTTAATGGGTAAAAACATTAAATTATTACAACATTTTTTCCAATAAAGCATAATAA
  ATAGAATCCATTTCTTTTAAAACGCTGTACAAGAGACTGGAAAACAAGCTTCCAACAGAA
  TATGAATAACTCATAACTCATTCTACCTTCTTATTGATTTGGGACGCTCCCCCCACCCCC
  CATGCCTGAAGCAACGTGCACACTTCAGGTCTCTGAGCACAGCCGGCCAAGGCCACCAGC
  TTCTAGGCTCCCTGGAGGTCATGACTTCACTCTTAAATGCTCTGCCCTTGGGTCTCGTCT
  GAGGCCCCAGCAGCCTGAGGCGCAGAAGAAACTGAACCGTTTAGGTGGCTGTGGCCTGCA
  GGAGCCCTTCTCTGTCCAACACACCAAAAGGAGTGAGAAAAACAAATGAGAAACGTCCCC
  CAAACACTCACACCCCCAAAACCAACACCTATAAGCCACAAACTGTGCTCCTCCCCTACT
  GCAGCAGTGGGCAGGAGAAACAAGAAGAGAAAGTGTTTCTTCCCCTCTCTTCTGATACAT
  AACCCCACGGGGTTCTCTTGCTGGAGAGGGTGACCCCAGATCACAGCGGGGCCACCATGT
  GGCCCTGCAGGATGTCCACGAGGTCCTGAGCCCCTCTCTGCAGTGCCAGCTCCAAGGGTG
  TGAGACCCCTGGCGTCCCTGCGATGGAGATCAGATTCAGCTGCCAGAAAGCTGACCACAG
  CAGTGTGACCCTCTTTGACTGCCAGATGGATTGGGAAGTGCCCCGNTGCCATCAGGGCAC
  GTGACATCAGCCCCGTGCTCCACTAGGACCTTCAGGNTGTNCAGNAATNCANTGCGGNCT
  GCGTCATGGACTGGACTGGTACCGGAGGTGTCCTGGAACTTTGGGCTGGCACCTTGCTTA
  GCACTNCAAGGCGATGGNCGTGCTGCCNACATCATGACCN
  
• Restriction Sites: NotI-NotI
• ACCN: NM_079421
• ORF Size: 501 bp
• Insert Size: 1000
• OTI Disclaimer: Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.
  
  The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info

Reference Data

• RefSeq: NM_079421.2, NP_524145.1
• RefSeq Size: 1162
• RefSeq ORF: 501
• Locus ID: 1032
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle
• Gene Summary: The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to form a stable complex with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. The abundance of the transcript of this gene was found to oscillate in a cell-cycle dependent manner with the lowest expression at mid G1 and a maximal expression during S phase. The negative regulation of the cell cycle involved in this protein was shown to participate in repressing neuronal proliferation, as well as spermatogenesis. Two alternatively spliced variants of this gene, which encode an identical protein, have been reported. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) contains a different 5' UTR region, and encodes an identical protein, as compared to variant 1.