PTP4A2 (NM_080392) Human Untagged Clone

CAT#: SC120384

PTP4A2 (untagged)-Human protein tyrosine phosphatase type IVA, member 2 (PTP4A2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PTP4A2
• Synonyms: HH7-2; HH13; HU-PP-1; OV-1; PRL-2; PRL2; ptp-IV1a; ptp-IV1b; PTP4A; PTPCAAX2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_080392 edited
  TAATGTTTTCTGCTGTGAAACATTTCAAGATTTATTGATTTTTTTTTTTCACTTTCCCCA
  TCACACTCACACGCACGCTCACACTTTTTATTTGCCATAATGAACCGTCCAGCCCCTGTG
  GAGATCTCCTATGAGAACATGCGTTTTCTGATAACTCACAACCCTACCAATGCTACTCTC
  AACAAGTTCACAGAGGAACTTAAGAAGTATGGAGTGACGACTTTGGTTCGAGTTTGTGAT
  GCTACATATGATAAAGCTCCAGTTGAAAAAGAAGGAATCCACGTTCTAGATTGGCCATTT
  GATGATGGAGCTCCACCCCCTAATCAGATAGTAGATGATTGGTTAAACCTGTTAAAAACC
  AAATTTCGTGAAGAGCCAGGTTGCTGTGTTGCAGTGCATTGTGTTGCAGGATTGGGAAGG
  GCACCTGTGCTGGTTGCACTTGCTTTGATTGAATGTGGAATGAAGTACGAAGATGCAGTT
  CAGTTTATAAGACAAAAAAGAAGGGGAGCGTTCAATTCCAAACAGCTGCTTTATTTGGAG
  AAATACCGACCTAAGATGCGATTACGCTTCAGAGATACCAATGGGCATTGCTGTGTTCAG
  TAGAAGGAAATGTAAACGAAGGCTGACTTGATTGTGCCATTTAGAGGGAACTCTTAATGT
  TTTCTGCTGTGAAACATTTCAAGATTTATTGATTTTTTTTTTTCACTTTCCCCATCACAC
  TCACACGCACGCTCACACTTTTTATTTGCCATAATGAACCGTCCAGCCCCTGTGGAGATC
  TCCTATGAGAACATGCGTTTTCTGATAACTCACAACCCTACCAATGCTACTCTCAACAAG
  TTCACAGAGGAACTTAAGAAGTATGGAGTGACGACTTTGGTTCGAGTTTGTGATGCTACA
  TATGATAAAGCTCCAGTTGAAAAAGAAGGAATCCACGTTCTAGATTGGCCATTTGATGAT
  GGAGCTCCACCCCCTAATCAGATAGTAGATGATTGGTTAAACCTGTTAAAAACCAAATTT
  CGTGAAGAGCCAGGTTGCTGTGTTGCAGTGCATTGTGTTGCAGGATTGGGAAGGGCACCT
  GTGCTGGTTGCACTTGCTTTGATTGAATGTGGAATGAAGTACGAAGATGCAGTTCAGTTT
  ATAAGACAAAAAAGAAGGGGAGCGTTCAATTCCAAACAGCTGCTTTATTTGGAGAAATAC
  CGACCTAAGATGCGATTACGCTTCAGAGATACCAATGGGCATTGCTGTGTTCAGTAGAAG
  GAAATGTAAACGAAGGCTGACTTGATTGTGCCATTTAGAGGGAACTCT
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_080392 unedited
  GTTCGGGATTTGTACACGACTCCTATAGGCGGCCCGCGAATTCGCACGAGGCCTCGTGCC
  GAATTCGGCACGAGGGCGCGCCGAGGCTGGGGGGGAGTCGTCGCCGCCGCCGCCACCGCT
  ACCGCCGCCGCCGCCGCCGCCGAGGTGACTGAGGAGAGAGGCGCCTCCTCGCTCCCGCCA
  CCGCCGGACTTCAATGCCCAGTCCCCAGCTCGCCAGCGTTTTTCGTTGGAATATACGTTG
  CACATTTATGGCGATTCTGAGTGTGAGGGCAGACTTCTGCCAGGCTCAGCACAGCATTTT
  CGCTGACAAGTGAGCTTGGAGGTTCTATGTGCCATAATTAACATTGCCTTGAAGACTCCT
  GGACACCGAGACTGGCCTCAGAAATAGTTGGCTTTTTTTTTTTTTTAATTGCAAGCATAT
  TTCTTTTAATGACTCCAGTAAAATTAAGCATCAAGTAAACAAGTGGAAAGTGACCTACAC
  TTTTAACTTGTCTCACTAGTGCCTAAATGTAGTAAAGGCTGCTTAAGTTTTGTATGTAGT
  TGGATTTTTTGGAGTCCGAAGGTATCCATCTGCAGAAATTGAGGCCCAAATTGAATTTGG
  ATTCAAGTGGATTCTAAATACTTTGCTTATCTTGAAGAGAGAAGCTTCATAAGGAATAAA
  CAAGTTGAATAGAGAAAACACTGATTGATAATAGGCATTTTAGCGGTCTTTCTAATGCTT
  TCTGCTGTGAAAATTTCAAGAATTATTGATTTTTTTTTTTTACTTTCCCCATCACACTCA
  CACGCACGCTCACACTTTTTATTTGCCATAATGAACCGTCCAGCCCCTGTGGGAGATCTC
  CTATGAGAACATGCGTTTTTCTGATAACTCACAACCCTACCCATGCTACTCTTAAACAGG
  TTCACAGAAGGAACTTAAGAG
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_080392 unedited
  GCGGCCGCAATCTAAAGTCGAGTTTTTTTTTTTTTTTTTTCTAAAATGCCCAGGTGGGCT
  TAAGGCTGCCAGACTGCACGCACATCTACAGCAACAAGGGCTTCTATTCCATCTACAACT
  TGGATCGGGGGAAAAGGGAGATGTAGGAGAGGAAGGAAAAAAGAGGGGAAAAATATACCA
  CCAACCCTCCCCCACAAAAAAAGGGAAAAAAAAAATCCCACCACAGGGAGATCTATGTGC
  CAAGCATAATGGAAGAGTGTGCTCCCCAAACAGATGGTTTTGCACAGGCTAATGTTCTGC
  TGGTTTTCCTTAGAGACCTATTTTGAAAAAGTTTAAAAAGACAGGAGATTTCAAAATAAT
  TCAATCCTGGCAGAAATTCAAACTCCAAAACTAGGAGCAAAATCATCCTTCACTGAATTA
  ATTCCTTTTCTCTTTCTCTTTTCTTAAACATTTTATTCATTTTATAGAGAGATTTCTTTT
  TTGTTTGCTTTTGTTCCAATCATTANGAGAGTGGTTGAGGAGTACTGAATCCATCACTAC
  TTTGATGACACAGGTAATATTCCAGATTCACATTTCCAGGTACCAAGAGTTCCCTCTAAA
  TGGCACAATCAAGTCAGCCCTCGTTTACATTTCCTTCTACTGAACACAGCAATGCCCATT
  GGTATCTCTGAAGCGTAATCGCATCTTAGGTCGGTATTTCCTCAATAAAGCAGCTGTTTG
  AATTTGAACGCTCCCCTCCTTTTTTGTCTATAAACTGAACTGCATNTTTGAACTTCATTC
  CACATCAATCAAAGCAGTGCAACAGGCCAGGTGCCTTTCCAAATCTTGAACCAATGGACT
  GGACAAAAAACCTGGTTTTCACAAATTGGGTTTTAACAGTTTAACCATCTTTACTACTGA
  TAAGGGGGGAGCTCTTATCCAGGGCATTTAAACGGGGATCCTTTTTTCACTGCGCTTATC
  CTAGGGCCTACAACTGACCAAGGGGACCCCACTTTTAGTCCTCGGGACTGGGAAGAG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_080392
• Insert Size: 1840 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_080392.2, NP_536317.1
• RefSeq Size: 1952 bp
• RefSeq ORF: 249 bp
• Locus ID: 8073
• Cytogenetics: 1p35.2
• Protein Families: Druggable Genome, Phosphatase
• Gene Summary: The protein encoded by this gene belongs to a small class of the protein tyrosine phosphatase (PTP) family. PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. PTPs in this class contain a protein tyrosine phosphatase catalytic domain and a characteristic C-terminal prenylation motif. This PTP has been shown to primarily associate with plasmic and endosomal membrane through its C-terminal prenylation. This PTP was found to interact with the beta-subunit of Rab geranylgeranyltransferase II (beta GGT II), and thus may function as a regulator of GGT II activity. Overexpression of this gene in mammalian cells conferred a transformed phenotype, which suggested its role in tumorigenesis. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 11, 12 and 17. [provided by RefSeq, Aug 2010]
  Transcript Variant: This variant (2) omits two alternate coding exons resulting in a frameshift. The protein isoform (2) is shorter than isoform 1 and has a distinct C-terminus.