DIS3L (NM_133375) Human Untagged Clone

CAT#: SC120532

DIS3L (untagged)-Human DIS3 mitotic control homolog (S. cerevisiae)-like (DIS3L), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: DIS3L
• Synonyms: DIS3L1
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC120532 sequence for NM_133375 edited (data generated by NextGen Sequencing)
  ATGCAGACAGCTTGTCAAGCTGTGCAGCATCAAAGAGGCAGGAGACAGTATAACAAACTG
  CGAAACCTGCTGAAGGATGCGCGTCATGATTGCATTCTCTTTGCTAATGAATTCCAGCAA
  TGCTGCTATCTGCCACGGGAAAGAGGAGAGTCCATGGAGAAGTGGCAGACCAGGAGCATA
  TACAACGCAGCTGTTTGGTACTATCATCACTGCCAGGACAGGATGCCAATTGTTATGGTG
  ACAGAAGATGAAGAGGCAATTCAGCAGTATGGAAGTGAAACAGAAGGAGTATTCGTGATT
  ACTTTCAAGAATTACCTGGACAATTTCTGGCCTGATTTAAAAGCTGCCCACGAGCTTTGT
  GATTCTATCCTTCAGTCTCGACGGGAGAGAGAGAATGAGAGTCAGGAGAGCCATGGGAAG
  GAGTACCCAGAACATCTTCCCCTGGAAGTGTTAGAAGCTGGGATTAAATCTGGACGCTAT
  ATCCAGGGAATTCTGAATGTCAACAAACACAGAGCCCAAATAGAAGCTTTTGTTCGACTT
  CAAGGAGCCAGCAGTAAAGATTCAGATTTAGTCAGTGACATCCTAATCCACGGGATGAAG
  GCTCGAAACCGCTCAATTCATGGAGATGTGGTAGTTGTGGAGCTGCTTCCTAAAAATGAA
  TGGAAAGGAAGAACCGTAGCCCTGTGTGAGAATGACTGTGACGACAAGGCTTCGGGCGAG
  TCCCCAAGTGAGCCCATGCCTACAGGTCGAGTGGTGGGCATACTTCAGAAGAACTGGCGG
  GATTATGTGGTGACATTTCCGTCCAAAGAAGAGGTCCAATCTCAGGGCAAAAATGCTCAG
  AAAATCCTGGTTACACCTTGGGATTACAGAATTCCCAAAATTCGAATTAGCACTCAGCAA
  GCAGAAACCCTCCAGGACTTCAGGGTGGTCGTGCGCATCGATTCCTGGGAGTCAACATCT
  GTGTATCCAAATGGACATTTTGTGCGTGTTTTAGGAAGAATCGGAGATCTGGAAGGGGAA
  ATTGCAACCATCCTGGTGGAAAACAGTATTTCAGTTATTCCTTTCTCAGAAGCTCAGATG
  TGTGAGATGCCAGTAAACACACCAGAAAGTCCCTGGAAGGTGAGTCCTGAAGAGGAACAA
  AAACGTAAAGACTTGAGGAAAAGCCATCTCGTATTCAGCATTGACCCCAAAGGTTGTGAA
  GATGTGGATGACACACTCTCAGTCAGAACCTTAAATAATGGCAACCTGGAACTTGGGGTC
  CACATCGCAGATGTAACACACTTTGTGGCACCAAATTCTTACATTGATATTGAAGCTAGA
  ACAAGGGCCACCACTTATTATCTAGCAGATCGTCGCTATGACATGCTGCCTTCCGTCCTC
  AGTGCAGATTTGTGTTCCCTTCTGGGAGGCGTTGATAGGTATGCTGTAAGCATCATGTGG
  GAACTGGATAAAGCCTCTTATGAAATTAAGAAAGTGTGGTATGGCAGAACCATTATTCGA
  TCAGCATACAAACTGTTCTATGAAGCAGCCCAAGAACTACTGGATGGAAACTTAAGCGTT
  GTTGATGATATTCCAGAATTCAAAGACTTGGGTGAGAAGAGCAGACAAGCCAAGCTGGAG
  GAGTTGGTGTGGGCAATTGGAAAGCTGACCGACATAGCTCGCCATGTCAGAGCTAAACGA
  GACGGATGTGGTGCCCTGGAACTGGAAGGGGTAGAGGTTTGCGTACAGCTAGATGACAAA
  AAGAACATTCACGACCTCATCCCCAAGCAGCCCCTGGAAGTCCACGAGACAGTGGCTGAA
  TGCATGATCCTGGCCAACCACTGGGTCGCCAAAAAGATCTGGGAGAGCTTCCCTCATCAG
  GCCTTGCTGCGCCAGCACCCTCCTCCACACCAGGAGTTCTTTTCAGAACTCCGGGAATGT
  GCTAAAGCCAAAGGCTTCTTCATAGATACACGGTCCAATAAAACACTGGCTGATTCTCTG
  GATAATGCGAACGACCCCCACGATCCCATTGTGAACAGGCTACTGCGCTCCATGGCCACG
  CAGGCCATGTCGAATGCTCTGTACTTCTCCACCGGATCCTGTGCGGAGGAGGAGTTCCAT
  CATTACGGTCTTGCATTAGATAAATATACCCACTTTACTTCTCCAATAAGAAGATATTCA
  GATATTGTAGTACACCGCTTGTTAATGGCAGCCATTTCAAAAGATAAGAAAATGGAAATT
  AAGGGAAATCTGTTCAGCAACAAAGATCTTGAGGAATTATGCAGACATATCAACAACAGA
  AACCAAGCAGCACAGCATTCTCAGAAGCAGTCTACTGAGCTCTTCCAGTGCATGTACTTC
  AAAGACAAAGACCCTGCCACCGAGGAGCGTTGCATATCTGACGGAGTTATTTATTCAATT
  AGAACAAATGGTGTGCTTCTATTTATACCAAGGTTTGGGATTAAAGGTGCTGCTTATCTA
  AAAAATAAAGATGGTTTAGTCATCTCATGTGGCCCAGATAGCTGTTCTGAATGGAAACCA
  GGATCCCTTCAACGATTTCAAAACAAAATTACCTCTACTACAACAGATGGGGAATCTGTT
  ACGTTCCATTTGTTTGACCATGTAACCGTAAGAATATCCATACAGGCCTCACGTTGCCAT
  TCTGATACAATCAGACTTGAAATAATTAGTAACAAACCATACAAGATACCAAATACAGAA
  CTTATTCATCAGAGTTCCCCCTTGCTGAAGAGTGAGTTAGTGAAAGAAGTAACTAAATCT
  GTGGAAGAAGCTCAGCTTGCCCAAGAAGTCAAAGTAAACATCATTCAGGAGGAATATCAA
  GAATATCGCCAAACAAAGGGAAGGAGCCTATACACACTTCTAGAGGAGATACGGGACCTA
  GCTCTCCTGGATGTTTCAAACAATTATGGAATATGA
  
  Clone variation with respect to NM_133375.3
  1592 a=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_133375 unedited
  NGGGGTCCCCATTAGTATACGACTCATATAGGCGGCNCGCGATTCGGCACGAGGTTCTTC
  ACCTGCCGTCCAGGTATCATCCTAGTCTTCCCTCCGTCTCTGGGATGGGAAACTCTTGTC
  TAGTGATGTGACTCATTACGTGATCCCAGACTGGAAAGTTGTTCAAGATTATCTTGAGAT
  CCTTGAGTTTCCTGAGTTGAAGGGAATTATTTTCATGCAGACAGCTTGTCAAGCTGTGCA
  GCATCAAAGAGGCAGGAGACAGTATAACAAACTGCGAAACCTGCTGAAGGATGCGCGTCA
  TGATTGCATTCTCTTTGCTAATGAATTCCAGCAATGCTGCTATCTGCCACGGGAAAGAGG
  AGAGTCCATGGAGAAGTGGCAGACCAGGAGCATATACAACGCAGCTGTTTGGTACTATCA
  TCACTGCCAGGACAGGATGCCAATTGTTATGGTGACAGAAGATGAAGAGGCAATTCAGCA
  GTATGGAAGTGAAACAGAAGGAGTATTCGTGATTACTTTCAAGAATTACCTGGACAATTT
  CTGGCCTGATTTAAAAGCTGCCCACGAGCTTTGTGATTCTATCCTTCAGTCTCGACGGGA
  GAGAGAGAATGAGAGTCAGGAGAGCCATGGGAAGGAGTACCCAGAACATCTTCCCCTGNA
  AGTGTTAGAAGCTGGGATTAAATCTGGACGCTATATCCAGGGAATTTCTGATGTCAACAA
  ACACAGAGCCCAAATAGAAGCTTTTGTTCGACTTCAAAGAGCCAGCAGTAAAGATTCAGA
  TTTAGTCAGTGACATCCTAATCCACGGGATGAAAGGCTCGAACCGCTCAATTCATGGAGA
  TGTGGTANNTGTGGGAGCTGCTTTCCTAAAATGAATGGNAAGGGAGAACCGTACCCCTGT
  GTGAGAATGACTGTGACA
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_133375 unedited
  CTACATCTAAGNAACCGCGGCCGCATTCTAGNGATCGATTTTTTTTTTTTTTTTTTGGAA
  AGGAGTCTCGCTCTGTTGCCCAGGCTCGGAAGCAGTGGTGCGATCTCGGCTCACTGCAAC
  CTCCTCTTCCTGGGTTCAGGCAATTCTCCTGCTTCAGCCTCCCAAGTAGCTGGGACTACA
  GGCGCATGCCACCACGCCGGGCTAATTTTTGTATTTTTAGTAGAGACTGGGTTTCACCGT
  GTTAGCCAGGATGGTCTCAATCTCCTGACCTCGTGATCCGCCCGCCTCAGCCTCCCAAAG
  TGCTGGGGTTACAGGCGTGAGCCACCGTGCCCGGCTGAGAACATTTTACATATATGCGAA
  ATAGCTACCCAGTCCTGATCGACTAGAGCACTGAGTGACACACATTAAATGTTAAGTTTG
  AAAAGACTGTAAAACATTCACATATGACAGCTCTTAGTGAAGTAAGAGCCTCTCATATTC
  CATAATTGTTTGAAACATCCAGGAGAGCTAGGTCCCGTATCTCCTCTAGAAGTGTGTATA
  GGCTCCTTCCCTTTGTTTGGCGATATTCTTGATATTCCTCCTGAATGATGTTTACTTTGA
  CTTCTTGGGCAAGCTGAGCTTCTTCCACAGATTTAGTTACTTCTTTCACTAACTCACTCT
  TCAGCAAGGGGGAACTCTGATGAATAAGTTCTGTATTTGGTATCTTGTATGGTTTGTTAC
  TAATTATTTCAAGTCTGATTGTATCAGAATGGCAACGTGGAGCCTGTATGGATATTCTTA
  CGGTTACATGGTCAAACCNATGGAACGTAACAGATTCCCCATCTGTTGTAGTAGAGGTAA
  TTTTGTTTTGAAATCTTTGAAGGATCCTGGTTCCATTCAAACAGCTATCTGGGCCCATGA
  AATT
  
• Restriction Sites: NotI-NotI
• ACCN: NM_133375
• ORF Size: 2916 bp
• Insert Size: 3700
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_133375.2, NP_588616.1
• RefSeq Size: 3685
• RefSeq ORF: 2916
• Locus ID: 115752
• Domains: RNB
• Gene Summary: The cytoplasmic RNA exosome complex degrades unstable mRNAs and is involved in the regular turnover of other mRNAs. The protein encoded by this gene contains 3'-5' exoribonuclease activity and is a catalytic component of this complex. [provided by RefSeq, May 2016]
  Transcript Variant: This variant (2) represents an alternate first exon and the transcript has a smaller open reading frame compared to variant 1. The resulting protein isoform (2) has a shorter N-terminus than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.