MLC1 (NM_139202) Human Untagged Clone

CAT#: SC120679

MLC1 (untagged)-Human megalencephalic leukoencephalopathy with subcortical cysts 1 (MLC1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: MLC1
• Synonyms: LVM; MLC; VL
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_139202, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGACCCAGGAGCCATTCAGAGAGGAGCTGGCCTATGACCGGATGCCCACGCTGGAGCGGGGCCGGCAAG
  ACCCCGCCAGCTATGCCCCAGACGCGAAGCCGAGCGACCTGCAGCTGTCGAAGAGACTGCCCCCCTGCTT
  CAGCCACAAGACGTGGGTCTTCTCTGTGCTGATGGGGAGCTGCCTCCTGGTGACCTCGGGGTTTTCGCTG
  TACCTGGGGAACGTGTTCCCGGCTGAGATGGATTACTTGCGCTGTGCTGCAGGCTCTTGCATCCCCTCGG
  CAATTGTGAGCTTCACCGTCTCCAGGAGGAACGCCAATGTGATTCCCAACTTTCAGATATTGTTTGTTTC
  CACGTTTGCTGTGACCACTACGTGTTTAATTTGGTTTGGATGCAAACTAGTCCTGAACCCATCAGCAATA
  AACATCAACTTCAACCTCATCCTGCTGCTCCTGCTGGAGCTGCTCATGGCGGCCACGGTGATCATCGCTG
  CACGGTCCAGCGAGGAGGACTGCAAGAAAAAGAAGGGCTCCATGTCTGACAGCGCCAACATTCTGGACGA
  AGTGCCATTTCCTGCTCGGGTCCTGAAATCTTACTCAGTCGTCGAGGTAATCGCAGGCATCTCTGCCGTC
  CTCGGGGGGATCATTGCCCTGAACGTGGATGACTCAGTTTCAGGCCCACACCTCTCAGTGACGTTCTTTT
  GGATCCTAGTGGCCTGCTTTCCAAGTGCCATTGCCAGTCATGTGGCAGCAGAGTGTCCCAGCAAGTGTCT
  GGTGGAGGTCCTGATTGCCATAAGCAGCCTCACGTCTCCGCTGCTGTTCACAGCCTCTGGATATCTGTCA
  TTCAGCATCATGAGAATCGTGGAGATGTTTAAGGATTACCCGCCAGCCATAAAACCATCCTACGATGTGC
  TGCTGCTGCTGCTGCTGCTAGTGCTCCTGCTGCAGGCCGGCCTCAACACGGGCACCGCCATCCAGTGCGT
  GCGCTTCAAGGTCAGTGCAAGGCTGCAGGGTGCATCCTGGGACACCCAGAACGGCCCGCAGGAGCGCCTG
  GCTGGGGAGGTGGCCAGGAGCCCCCTGAAGGAGTTCGACAAGGAGAAAGCCTGGAGAGCCGTCGTGGTGC
  AAATGGCCCAGTGA
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_139202 unedited
  TACGACTCACTATAGGGCGGCCGCGAATTCGCACGAGGACCAATTGGAGCAGTTTAACGT
  GCTTGAGTCCCCGGCGTGATGTGTTCATGGACGAAGTTGCCGATGGATGTTGTCAGGTGT
  TGCACCTGGAGGGCCCAGATGGATCAATGAGGCATTTAAAGTGTAGAATCTCACCCTGAA
  CCCAGACTATTCAGATAAAGAACTGGTGACACGTGGCTGTACATTCAGCACAGCTGTGGT
  GTCCCCAAGTGCCATGACCCAGGAGCCATTCAGAGAGGAGCTGGCCTATGACCGGATGCC
  CACGCTGGAGCGGGGCCGGCAAGACCCCGCCAGCTATGCCCCAGACGCGAAGCCGAGCGA
  CCTGCAGCTGTCGAAGAGACTGCCCCCCTGCTTCAGCCACAAGACGTGGGTCTTCTCTGT
  GCTGATGGGGAGCTGCCTCCTGGTGACCTCGGGGTTTTCGCTGTACCTGGGGAACGTGTT
  CCCGGCTGAGATGGATTACTTGCGCTGTGCTGCAGGCTCTTGCATCCCCTCGGCAATTGT
  GAGCTTCACCGTCTCCAGGAGGAACGCCAATGTGATTCCCAACTTTCAGATATTGTTTGT
  TTCCACGTTTGCTGTGACCACTACGTGTTTAATTTGGTTTGGATGCAAACTAGTCCTGAA
  CCCATCAGCATAAACATCAACTTCAACCTCATNCTGCTGCTCCTGCTGGAGCTGCTCATG
  GCGGCCACGGTGATCATCGCTGCACGGTCCAGCGAGGGAGACTGCNAGANAAGAAGGGCT
  CCATGTCTGACAGCGCCACATTCTGNACGAGTGCCATTTCTGGCTCGGTCCTGAATCTTA
  CTCAGCCGCGAGTAATCGCAGCATTCTGCGTCTGGGGGGGACATGCCTGACGTGATACTA
  GTTTAGCCCACTTCAAGGAGTTTTTTGATCTAGGGCTGCTCCAGGCATGCAGATGGGAAC
  AATGCCAT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_139202 unedited
  AAATCTTGNACCCGCGGCCGCAATCTACNGATCGGTTTTTTTTTTTTTTTTTTCACGTCT
  GCAAGTCAGCGTTTATTGCTCAAGCGTATTAAACAAAAATGTAGACTGAAAGAGACAGTT
  CTTTTAAACCCCATTTTTCCGGATTTTTTAAGCGCTCTAAAATAAGAAAATAAGAAAGTG
  CAAGCCAGCAAAAACGCTCCAAGTGCCTAATTCTGACTCTGAAACTTGAGCTCTCTGGTC
  TGCCCCCAAGAAGACATCAGCCCGCCCCGGGTCGTCCCTGTGGCTCCCACCCCATTCCCA
  GGAGCAGACCCCGCCAGCCTCAAAGCTGCAGGGAGGTGGGGGTGGCCTGCAAACAGGGTG
  GGGTCTGCATCCGGTACCAGTGACAGCAGCCTCTCCTCTCCCACGGTGGCGCTTGTTTGG
  GGCTGTGGCCAAAGTGTTTGCCCGGCCCCTGACTGTGTCCTTCCGGAGCTGCCGAGGACT
  GAAGAGAGGGCCTGGCTTGTCCCCCTCTAGGAGCAGCTGGGAAGGTGTCTTGCCTGCATC
  CCCCTTAAATGGTTGAAAATATTGATTCCACTTGCCATGAACACCATGAAGGTATCTTTG
  GCAGCCAGAGTCACTCCTGTTCCGCAGTGGGAAACCTGGGAGGGTCCTCAAACCCCCTGC
  AGGGTCTGAAGGCCGCCCATTCAACTGCATTTCCCAGCCCTCCTGGTTTTTGATCTTGAT
  GGCCCCAGGCCCAAGAAGCATTTCCGGGCCTTTCAGCAGCCCAGGGGGGACCAGTTAATA
  CCCCCCCAGGGGGTGAAAACCAAACGTTCATGTTTTCCCCGACCGAAGGCAAGAACCAAA
  CCTTTGGGAGGAAAACCCTGCTGAAAGTAATACAAGGCCCACATTCCCGTTCACAGCGCC
  CCACTCATGGGATTTACTGCTGTACTTGGCAGG
  
• Restriction Sites: NotI-NotI
• ACCN: NM_139202
• ORF Size: 1134 bp
• Insert Size: 3780
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_139202.1, NP_631941.1
• RefSeq Size: 3572
• RefSeq ORF: 1134
• Locus ID: 23209
• Protein Families: Ion Channels: Other, Transmembrane
• Gene Summary: The function of this gene product is unknown; however, homology to other proteins suggests that it may be an integral membrane transporter. Mutations in this gene have been associated with megalencephalic leukoencephalopathy with subcortical cysts, an autosomal recessive neurological disorder. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2) contains a different 5' noncoding exon compared to transcript variant 1, thus has a distinct 5' UTR. Both variants encode the same protein.