NRP2 (NM_003872) Human Untagged Clone

CAT#: SC121198

NRP2 (untagged)-Human neuropilin 2 (NRP2), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NRP2
• Synonyms: NP2; NPN2; PRO2714; VEGF165R2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene ORF within SC121198 sequence for NM_003872 edited (data generated by NextGen Sequencing)
  ATGGATATGTTTCCTCTCACCTGGGTTTTCTTAGCCCTCTACTTTTCAAGACACCAAGTG
  AGAGGCCAACCAGACCCACCGTGCGGAGGTCGTTTGAATTCCAAAGATGCTGGCTATATC
  ACCTCTCCCGGTTACCCCCAGGACTACCCCTCCCACCAGAACTGCGAGTGGATTGTTTAC
  GCCCCCGAACCCAACCAGAAGATTGTCCTCAACTTCAACCCTCACTTTGAAATCGAGAAG
  CACGACTGCAAGTATGACTTTATCGAGATTCGGGATGGGGACAGTGAATCCGCAGACCTC
  CTGGGCAAACACTGTGGGAACATCGCCCCGCCCACCATCATCTCCTCGGGCTCCATGCTC
  TACATCAAGTTCACCTCCGACTACGCCCGGCAGGGGGCAGGCTTCTCTCTGCGCTACGAG
  ATCTTCAAGACAGGCTCTGAAGATTGCTCAAAAAACTTCACAAGCCCCAACGGGACCATC
  GAATCTCCTGGGTTTCCTGAGAAGTATCCACACAACTTGGACTGCACCTTTACCATCCTG
  GCCAAACCCAAGATGGAGATCATCCTGCAGTTCCTGATCTTTGACCTGGAGCATGACCCT
  TTGCAGGTGGGAGAGGGGGACTGCAAGTACGATTGGCTGGACATCTGGGATGGCATTCCA
  CATGTTGGCCCCCTGATTGGCAAGTACTGTGGGACCAAAACACCCTCTGAACTTCGTTCA
  TCGACGGGGATCCTCTCCCTGACCTTTCACACGGACATGGCGGTGGCCAAGGATGGCTTC
  TCTGCGCGTTACTACCTGGTCCACCAAGAGCCACTAGAGAACTTTCAGTGCAATGTTCCT
  CTGGGCATGGAGTCTGGCCGGATTGCTAATGAACAGATCAGTGCCTCATCTACCTACTCT
  GATGGGAGGTGGACCCCTCAACAAAGCCGGCTCCATGGTGATGACAATGGCTGGACCCCC
  AACTTGGATTCCAACAAGGAGTATCTCCAGGTGGACCTGCGCTTTTTAACCATGCTCACG
  GCCATCGCAACACAGGGAGCGATTTCCAGGGAAACACAGAATGGCTACTACGTCAAATCC
  TACAAGCTGGAAGTCAGCACTAATGGAGAGGACTGGATGGTGTACCGGCATGGCAAAAAC
  CACAAGGTATTTCAAGCCAACAACGATGCAACTGAGGTGGTTCTGAACAAGCTCCACGCT
  CCACTGCTGACAAGGTTTGTTAGAATCCGCCCTCAGACCTGGCACTCAGGTATCGCCCTC
  CGGCTGGAGCTCTTCGGCTGCCGGGTCACAGATGCTCCCTGCTCCAACATGCTGGGGATG
  CTCTCAGGCCTCATTGCAGACTCCCAGATCTCCGCCTCTTCCACCCAGGAATACCTCTGG
  AGCCCCAGTGCAGCCCGCCTGGTCAGCAGCCGCTCGGGCTGGTTCCCTCGAATCCCTCAG
  GCCCAGCCCGGTGAGGAGTGGCTTCAGGTAGATCTGGGAACACCCAAGACAGTGAAAGGT
  GTCATCATCCAGGGAGCCCGCGGAGGAGACAGTATCACTGCTGTGGAAGCCAGAGCATTT
  GTGCGCAAGTTCAAAGTCTCCTACAGCCTAAACGGCAAGGACTGGGAATACATTCAGGAC
  CCCAGGACCCAGCAGCCAAAGCTGTTCGAAGGGAACATGCACTATGACACCCCGGACATC
  CGAAGGTTTGACCCCATTCCGGCACAGTATGTGCGGGTATACCCGGAGAGGTGGTCGCCG
  GCGGGGATTGGGATGCGGCTGGAGGTGCTGGGCTGTGACTGGACAGACTCCAAGCCCACG
  GTAGAGACGCTGGGACCCACTGTGAAGAGCGAAGAGACAACCACCCCCTACCCCACCGAA
  GAGGAGGCCACAGAGTGTGGGGAGAACTGCAGCTTTGAGGATGACAAAGATTTGCAGCTC
  CCTTCGGGATTCAATTGCAACTTCGATTTCCTCGAGGAGCCCTGTGGTTGGATGTATGAC
  CATGCCAAGTGGCTCCGGACCACCTGGGCCAGCAGCTCCAGCCCAAACGACCGGACGTTT
  CCAGATGACAGGAATTTCTTGCGGCTGCAGAGTGACAGCCAGAGAGAGGGCCAGTATGCC
  CGGCTCATCAGCCCCCCTGTCCACCTGCCCCGAAGCCCGGTGTGCATGGAGTTCCAGTAC
  CAGGCCACGGGCGGCCGCGGGGTGGCGCTGCAGGTGGTGCGGGAAGCCAGCCAGGAGAGC
  AAGTTGCTGTGGGTCATCCGTGAGGACCAGGGCGGCGAGTGGAAGCACGGGCGGATCATC
  CTGCCCAGCTACGACATGGAGTACCAGATTGTGTTCGAGGGAGTGATAGGGAAAGGACGT
  TCCGGAGAGATTGCCATTGATGACATTCGGATAAGCACTGATGTCCCACTGGAGAACTGC
  ATGGAACCCATCTCGGCTTTTGCAGTGGACATCCCAGAAATACATGAGAGAGAAGGATAT
  GAAGATGAAATTGATGATGAATACGAGGTGGACTGGAGCAATTCTTCTTCTGCAACCTCA
  GGGTCTGGCGCCCCCTCGACCGACAAAGAAAAGAGCTGGCTGTACACCCTGGATCCCATC
  CTCATCACCATCATCGCCATGAGCTCACTGGGCGTCCTCCTGGGGGCCACCTGTGCAGGC
  CTCCTGCTCTACTGCACCTGTTCCTACTCGGGCCTGAGCTCCCGAAGCTGCACCACACTG
  GAGAACTACAACTTCGAGCTCTACGATGGCCTTAAGCACAAGGTCAAGATGAACCACCAA
  AAGTGCTGCTCCGAGGCATGA
  
  Clone variation with respect to NM_003872.2
  1071 t=>c;1674 t=>g
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_003872 unedited
  CCGCGGAATCGGCACGAGGCACCAGCCTGCAGCCGGCCCCCAGCACATCCTCAGCCGCAC
  AGACACTCGGCGAGGTGGAGGTGAGGGCGGGCGCCAGCGAACTCGGAGAGGGGCTCGCTC
  ACTCCCAGGCGATCCCAGCCGCCACCGCCGCCGCACCAGCAGCAGCAACAGCAGCAGCAG
  CTTCCTTCCTCAGACTCCCCTCGAGAGGCTGGCCAAGCGGGTGTAGCCGTTGGGGGAGGC
  TCCCGCCGGGGGAACCCGGCGAGGACAAGAGCAGGGCGGCCGCCTTCCACTCGGGCTGTC
  CGGCGGCGGCTGCCTCCGCCCGCGTGTCCGTCAAGGGTGCCGCGGGATGTGTGTCAGTTT
  ACGCCTCTGAGATCACACAGCTGCCTGGGGGCCGTGTGATGCCCAAGGCAAGTCTTGGTT
  TTAATTATTATTATTATCATTATTGTTACGCTTGGCTTTCGGGAAATACTCGTGATATTT
  GTAGGATAAAGGAAATGACACTTTGAGGAACTGGAGAGAACATATATGCGTTTTGTTTTT
  AAGAGGAAAACCGTGTTCTCTTCCCGGCTTGTTCCCTCTTTGCTGATTTCAGGAGCTACT
  CTCCTCCTGGTGAGGTGGAAATTCCAGCAAGAATAGAGGTGAAGACAAGCCACCAGGACT
  CAGGAGGGAAACGCTGACCATTAGAAACCTCTGCATAAGACGTTGTAAGGAGGAAAATAA
  TAGAGAGAAGAACACATAGATTTAAACAAGAAACCTACGAACCCAGCTCTGGAAAGAGCC
  ACCTTCTNCAAATGGATATGTTTCCTCTCACCTGGGATGTCTAGCCCTCTACTTTTCAGA
  CACCAGTGAGAGGCCACCAGACCCACGTGCGGNAGTCGNTTGAATCC
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_003872 unedited
  NGACTTTTGTGGTTGTTTATCCAATTTTAATCTTAAAAGGCTTTATACAAATCATATAAA
  CACAGTTTGACATTGTTGTTTATTTTTTAACATTGAAGAATCACAGTAAAAGCTCTCAAG
  TTCCCGTGATCTGGCTCAGCCAGTGAATGGTCGAATACCTCTAACTGCAAACCCTGAAAA
  AGTTAACCTGCTATGTGACAGGTTAACTCTTTCCCTTGTTTTCTTGTCATTCATGCTTAT
  TCCTTGGACCCTCATCCCTGTCAACTCCCCTGCCCCACCAAAGACAGAAAGCAACCCTGT
  GGCCCTGTTGACCACCTAGTCCGGGAGAGTGTGGAGGTAATGTGTCATTCAGTACAAGGC
  AAAAAGGAGATCAATACTGGCAGTGGGGTTTCCCAAAGGGAATGACTCAAGGAGATGGGT
  CAGCTAGCCTACCCACAGATAAAGATAACAAACACACCAAGGTGTCCCCTGGCCAAGTCA
  AAATTGGGCCCAGCGTCTTTCTTTCTGTCTTACGACAGAGCAGCCTCCAGCCTTGGTGTG
  GTATCTACATGTAGCCCTCCGTACCCTGCTTCTTTTTAGCATTCAAGGCCCACTCAGGGC
  CTCAAATTAGCCAATGGTGAATATGGATATAGGACTTTTAGAGGGATGCAGGTTGAGTTG
  TACATAACTTATAGGTGAAGTGCAAGTCCGAAACAGGGCTAGACTTTGGAGAACTGGTAA
  ATGGCTCACTGAGCATGACAGCATCAGGGACCCCTGAGAGTGGCTTTCAAAACTTACCTT
  CCTTTTGCAAGCTACCTTCTGGGAAAATCGCTAAGGACTTACCCAGCCTTTCTGAACACT
  GTCGCATCATGGGTAGTGTGAAGAGGAAAAGGGGCCTAGTTAAATACTTGCTTCTACTGT
  GGGCCGCAACTCAGGAAGGAGCCCTATAACCTAATCCCTTGGGCC
  
• Restriction Sites: NotI-NotI
• ACCN: NM_003872
• ORF Size: 2781 bp
• Insert Size: 6550
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_003872.2, NP_003863.2
• RefSeq Size: 6656
• RefSeq ORF: 2781
• Locus ID: 8828
• Protein Families: Druggable Genome, Transmembrane
• Gene Summary: This gene encodes a member of the neuropilin family of receptor proteins. The encoded transmembrane protein binds to SEMA3C protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C} and SEMA3F protein {sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F}, and interacts with vascular endothelial growth factor (VEGF). This protein may play a role in cardiovascular development, axon guidance, and tumorigenesis. Multiple transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
  Transcript Variant: This variant (2), also known as NRP2a(17), lacks an alternate in-frame segment, compared to variant 1. This results in a shorter isoform (2), compared to isoform 1.