E2F2 (BC007609) Human Untagged Clone

CAT#: SC122267

E2F2 (untagged)-Homo sapiens, Similar to hypothetical protein PRO1722, clone MGC:15692 IMAGE:3351479, complete cds


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    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol E2F2
Synonyms E2F-2; E2F transcription factor 2; OTTHUMP00000003257
Vector pCMV6-XL5
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene sequence for BC007609 edited
CTAGAATGCTAATTGCACTTAGGCCTCATGGTTCTAGTAAACGGCAGCTGTGGGCCCTTT
TGCCTCTTCCCCTGTTCTTGGCCTCACATCTCCAGCTGAGCTGCCGGTCTTGGCTTCCTG
GTCGCCTCTGTCCCAGAGATGGTCCCAGGGAGCCATCCTAGGGCAGGTAGCACTGAGGCT
CCTGTGGAAACAGGAGCCACCTGCTCAGGAGACCCCTTTCCTGAGGAAGTCCTTACCTCT
CCCCTTGAGATGTAAAAATGGTCCAGCAGAGACAAGCTCCCGTGGAAAACAGACAGGAGC
ATGGGGGCAGCTGTCATGGCTGTGGCGGGCACTTTTCCTCAGAGTTTCTGCCTTGCGCTG
GTCCAGGAGCCATTTTGCACCAAGGACTTGGTAGGCAGAGGCAGCCCCACTGTAAAGAAG
GGTCAGATTAAAACAAAAAACTGCCAAAAGCATCCCCTCTGCCCCCCATGTGGCACTGGC
ATCATTCTCTGCTTCCCTGGGAGGAATTTTTTCACCATGTTATTGAAGGGGATGGTTCAT
TAAGGACTCCACCCCTCAGAGCTCACTCAGACCCCAAGGACAGAGGTGACTGGGGCTTGG
TGACTTGTTCACTCCTTTTTTCCCAGGTATACTGAAGGGGTGACAGAGAGAGGTCTTCAT
GGCAGACCAGGCCTTCACAGCTAATGGGGAGAGGAACTCATGTTACCTCTGCAGGCCTGG
GGTCCTGAGGGGGTCTTTTGGCTTCAGCCTGTTCCCCCAGAGGCTTGATCATCCCACATT
GTCCCTTCAGCTCAGCTGCTCTTCTCCCCCACCCACCCTGGGATGTGGGTGCTCTGGGCT
GAACCAAGGCTATGACTTCTGGAGAGAGGCTCAGGGGTTGGTCTGAGAGGCCTGCCATCC
ACCCCTCAGGGAGCTAGGTTTTCTCAGAGGCTCAGCTGGACAGCACTTTTTAGAAAAGTT
TGTAGCATTAAGCTGGTTTAAAATATGAAGTTGGTTTTGTTGGATGGCTCCTGAGCTGAC
TGACTGATGTCTGAAGTTTGAGACGAGGGATTATTTCAGGGTGGGGCCCAATGTGATCTA
ATGCCCAGCTGGGGACAATTGTGCCTCATCATTTGCTCAAATTCCTGGGCCCCCAAGTTA
GCCCCCTCCCAGGAGTGGTCAGCGGGTCACAGCTGCCCCCACTCTATAAGCAGGGCTAAT
TGTGTACCCTTTGCAGAAATGCTTTTGGTCTCCTACCCAAATACTCACAAGGGTCTTATC
AGACGCCCGTCTTAAAGTCCAGCATGCTCAGGGACCCTGTGTAGGATCTCGTTTGTGGTG
AGTGGGCTGCTCTGAGGTCTCCACTGGGCTGCCATTTAGCCATGTGCCATCTCTGAAGTC
AGAGGTGTTTGACTCCCATTCCTTGGGCTCTGGAGCTTTCCCCAAGAATTACATCAGAGA
AAAGGAAGAAGGGGCCTGCAGGACCCATTGGGAATGAGTTTAATACTGAAGTCTGGAATG
TAAGCTCATGCCCTAGAGGCCTCTCCATATGGCTGGTCAGGGGAGCTGCCTTCAGGCTTG
TGCCCCGTGTGCTCAGCAGCTGCCTCTGTCCCCCTCTACTGTCCCTTTCACACCTTGCCT
GGCCAAGGGGCTAGACCTCCCAGGCTAAGCCTCAGATTCAGTGCAGGACACAAGCTCATG
CCCCCGTCTTGCCAGTGACACTTGAAGCCTCCCGACTTCCACAGAGTGCTTCAGGACACA
TTTTGAGTGGTATTTTCTTTTCTTTTTTTCTTCTTTTTTTTTTTTTTGAGATGGAGTCTC
GCTCTGTTGCCCAGGCTGGAGTGCAGTGGCCTGATCTCGGCTCACTGCAACCTCTGCCTC
CCAGGTTCAAGCGATTCTTCTGCCTCAGCCTCCAGAGTAGCTGGGACTATAGACATGCAC
CACCACGCCCGGCTAATTTTGTATTTTTGGTCGAGACGGGGTTTTGCCATGTTAGTCAGG
CTGGTCTTGAACTCCTGACCTCAAGTGATCCACCACCTCGGCCTCCCAAAGTGTTGAGAT
GACAGGCACGAGCCACCAGGCCCAGCCTGAGTGGTATTTTCTTTAGGGACCAGGTAGACT
TTAAAACGAGGGTAAGAGAAAAGCCAGTGTCTTTCTGAGGTAAATAATTTCTGCCAGGAA
ACTTCCCAGCCCCACCAGCAGCCCCCCTAAAAAAATCACTCGTGTCCCCAGGGACTTCTA
AAGCTTGGGGCTCCAGGAAATCATCCAGTAGAGTTGGAGATTCAGAGATTTCTTGAAGCC
AGGGACATGCTCCTAACTCCTTTCCCATTAAAGGTGTTAGAATAGACCAGAGGGTGTCCC
TTTTCCACAGTAATGGGATCGGCTGGTGTGCCTTCAGGGAGGAAGAGGGAGGTGGTCAAG
CTTGAAAAACTGGCTTTAGGATGGTTCTGACTTTGTTCTCCCTCCCCAAGTGTTCTCAAC
CTCCATTCTGCAGTGTTCAGAGTTTTAGGGAAAGGGTTTGGGTGCCCCAGCATCCAGGTG
TTGTGTGGCTTAGCGCATGTGAAGTGAAAACCTTCTGGGGTTGTTTGGAAGCAGCTTTCT
GGTTCTTGTGATTGTATCCTGAGGTCCCAGAACCCTATTCTCCCACGAGGATCCTCAGTG
ACCATGGTGGCCACACGCCTGGCCAGCCTGCTGGCTCCTGGGTGAGCTGAAGAACCTTGC
CTGTGGCACTTTTCGAGGGTGAGCTGGAACCGAGAGAACATGGTCCCCGTGCTGGGACTC
ATGCGGGTCATTTCCTGCCGGCCTGGTTTCGCCTGGTCGTGTCTTTATGAGCACCATGTA
AGCCTCCTTGTATTGAGATAATTGGGCATTAAACATTAAACTGCAGCTCTGGGAAAAAAA
AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAC
>OriGene 5' read for BC007609 unedited
AGCGTACAAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTAGAA
TGCTAATTGCACTTAGGCCTCATGGTTCTAGTAAACGGCAGCTGTGGGCCCTTTTGCCTC
TTCCCCTGTTCTTGGCCTCACATCTCCAGCTGAGCTGCCGGTCTTGGCTTCCTGGTCGCC
TCTGTCCCAGAGATGGTCCCAGGGAGCCATCCTAGGGCAGGTAGCACTGAGGCTCCTGTG
GAAACAGGAGCCACCTGCTCAGGAGACCCCTTTCCTGAGGAAGTCCTTACCTCTCCCCTT
GAGATGTAAAAATGGTCCAGCAGAGACAAGCTCCCGTGGAAAACAGACAGGAGCATGGGG
GCAGCTGTCATGGCTGTGGCGGGCACTTTTCCTCAGAGTTTCTGCCTTGCGCTGGTCCAG
GAGCCATTTTGCACCAAGGACTTGGTAGGCAGAGGCAGCCCCACTGTAAAGAAGGGTCAG
ATTAAAACAAAAAACTGCCAAAAGCATCCCCTCTGCCCCCCATGTGGCACTGGCATCATT
CTCTGCTTCCCTGGGAGGAATTTTTTCACCATGTTATTGAAGGGGATGGTTCATTAAGGA
CTCCACCCCTCAGAGCTCACTCAGACCCCAAGGACAGAGGTGACTGGGGCTTGGTGACTT
GTTCACTCCTTTTTTCCCCAGTATACTGAANGGGTGACAGAGAGAGGTCTTCATGGCAGA
CCAGGCCTTCACAGCTAATGGGGAGAGGAACTCATGTTACCTCTGCAGGCCTGGGGTCCC
TGAGGGGTCTTTTGGCTTCAGCCTGTTCCCCCAGAAGCTTGATCATCCCACATTGTCCCT
TCAGCTCAGCTGCTCTTCTTCCCCACCCACCCTGGGATGGTGGTGCTCTGGGCCTGACCC
AAGCTATGACTTCTG
Restriction Sites Please inquire     
ACCN BC007609
Insert Size 2917
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq BC007609.1, AAH07609.1
RefSeq Size 2917
Locus ID 1870
Protein Families Druggable Genome, Transcription Factors
Protein Pathways Bladder cancer, Cell cycle, Chronic myeloid leukemia, Glioma, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer
Gene Summary The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. [provided by RefSeq, Jul 2008]

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