E2F2 (BC007609) Human Untagged Clone

CAT#: SC122267

E2F2 (untagged)-Homo sapiens, Similar to hypothetical protein PRO1722, clone MGC:15692 IMAGE:3351479, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: E2F2
• Synonyms: E2F-2; E2F transcription factor 2; OTTHUMP00000003257
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC007609 edited
  CTAGAATGCTAATTGCACTTAGGCCTCATGGTTCTAGTAAACGGCAGCTGTGGGCCCTTT
  TGCCTCTTCCCCTGTTCTTGGCCTCACATCTCCAGCTGAGCTGCCGGTCTTGGCTTCCTG
  GTCGCCTCTGTCCCAGAGATGGTCCCAGGGAGCCATCCTAGGGCAGGTAGCACTGAGGCT
  CCTGTGGAAACAGGAGCCACCTGCTCAGGAGACCCCTTTCCTGAGGAAGTCCTTACCTCT
  CCCCTTGAGATGTAAAAATGGTCCAGCAGAGACAAGCTCCCGTGGAAAACAGACAGGAGC
  ATGGGGGCAGCTGTCATGGCTGTGGCGGGCACTTTTCCTCAGAGTTTCTGCCTTGCGCTG
  GTCCAGGAGCCATTTTGCACCAAGGACTTGGTAGGCAGAGGCAGCCCCACTGTAAAGAAG
  GGTCAGATTAAAACAAAAAACTGCCAAAAGCATCCCCTCTGCCCCCCATGTGGCACTGGC
  ATCATTCTCTGCTTCCCTGGGAGGAATTTTTTCACCATGTTATTGAAGGGGATGGTTCAT
  TAAGGACTCCACCCCTCAGAGCTCACTCAGACCCCAAGGACAGAGGTGACTGGGGCTTGG
  TGACTTGTTCACTCCTTTTTTCCCAGGTATACTGAAGGGGTGACAGAGAGAGGTCTTCAT
  GGCAGACCAGGCCTTCACAGCTAATGGGGAGAGGAACTCATGTTACCTCTGCAGGCCTGG
  GGTCCTGAGGGGGTCTTTTGGCTTCAGCCTGTTCCCCCAGAGGCTTGATCATCCCACATT
  GTCCCTTCAGCTCAGCTGCTCTTCTCCCCCACCCACCCTGGGATGTGGGTGCTCTGGGCT
  GAACCAAGGCTATGACTTCTGGAGAGAGGCTCAGGGGTTGGTCTGAGAGGCCTGCCATCC
  ACCCCTCAGGGAGCTAGGTTTTCTCAGAGGCTCAGCTGGACAGCACTTTTTAGAAAAGTT
  TGTAGCATTAAGCTGGTTTAAAATATGAAGTTGGTTTTGTTGGATGGCTCCTGAGCTGAC
  TGACTGATGTCTGAAGTTTGAGACGAGGGATTATTTCAGGGTGGGGCCCAATGTGATCTA
  ATGCCCAGCTGGGGACAATTGTGCCTCATCATTTGCTCAAATTCCTGGGCCCCCAAGTTA
  GCCCCCTCCCAGGAGTGGTCAGCGGGTCACAGCTGCCCCCACTCTATAAGCAGGGCTAAT
  TGTGTACCCTTTGCAGAAATGCTTTTGGTCTCCTACCCAAATACTCACAAGGGTCTTATC
  AGACGCCCGTCTTAAAGTCCAGCATGCTCAGGGACCCTGTGTAGGATCTCGTTTGTGGTG
  AGTGGGCTGCTCTGAGGTCTCCACTGGGCTGCCATTTAGCCATGTGCCATCTCTGAAGTC
  AGAGGTGTTTGACTCCCATTCCTTGGGCTCTGGAGCTTTCCCCAAGAATTACATCAGAGA
  AAAGGAAGAAGGGGCCTGCAGGACCCATTGGGAATGAGTTTAATACTGAAGTCTGGAATG
  TAAGCTCATGCCCTAGAGGCCTCTCCATATGGCTGGTCAGGGGAGCTGCCTTCAGGCTTG
  TGCCCCGTGTGCTCAGCAGCTGCCTCTGTCCCCCTCTACTGTCCCTTTCACACCTTGCCT
  GGCCAAGGGGCTAGACCTCCCAGGCTAAGCCTCAGATTCAGTGCAGGACACAAGCTCATG
  CCCCCGTCTTGCCAGTGACACTTGAAGCCTCCCGACTTCCACAGAGTGCTTCAGGACACA
  TTTTGAGTGGTATTTTCTTTTCTTTTTTTCTTCTTTTTTTTTTTTTTGAGATGGAGTCTC
  GCTCTGTTGCCCAGGCTGGAGTGCAGTGGCCTGATCTCGGCTCACTGCAACCTCTGCCTC
  CCAGGTTCAAGCGATTCTTCTGCCTCAGCCTCCAGAGTAGCTGGGACTATAGACATGCAC
  CACCACGCCCGGCTAATTTTGTATTTTTGGTCGAGACGGGGTTTTGCCATGTTAGTCAGG
  CTGGTCTTGAACTCCTGACCTCAAGTGATCCACCACCTCGGCCTCCCAAAGTGTTGAGAT
  GACAGGCACGAGCCACCAGGCCCAGCCTGAGTGGTATTTTCTTTAGGGACCAGGTAGACT
  TTAAAACGAGGGTAAGAGAAAAGCCAGTGTCTTTCTGAGGTAAATAATTTCTGCCAGGAA
  ACTTCCCAGCCCCACCAGCAGCCCCCCTAAAAAAATCACTCGTGTCCCCAGGGACTTCTA
  AAGCTTGGGGCTCCAGGAAATCATCCAGTAGAGTTGGAGATTCAGAGATTTCTTGAAGCC
  AGGGACATGCTCCTAACTCCTTTCCCATTAAAGGTGTTAGAATAGACCAGAGGGTGTCCC
  TTTTCCACAGTAATGGGATCGGCTGGTGTGCCTTCAGGGAGGAAGAGGGAGGTGGTCAAG
  CTTGAAAAACTGGCTTTAGGATGGTTCTGACTTTGTTCTCCCTCCCCAAGTGTTCTCAAC
  CTCCATTCTGCAGTGTTCAGAGTTTTAGGGAAAGGGTTTGGGTGCCCCAGCATCCAGGTG
  TTGTGTGGCTTAGCGCATGTGAAGTGAAAACCTTCTGGGGTTGTTTGGAAGCAGCTTTCT
  GGTTCTTGTGATTGTATCCTGAGGTCCCAGAACCCTATTCTCCCACGAGGATCCTCAGTG
  ACCATGGTGGCCACACGCCTGGCCAGCCTGCTGGCTCCTGGGTGAGCTGAAGAACCTTGC
  CTGTGGCACTTTTCGAGGGTGAGCTGGAACCGAGAGAACATGGTCCCCGTGCTGGGACTC
  ATGCGGGTCATTTCCTGCCGGCCTGGTTTCGCCTGGTCGTGTCTTTATGAGCACCATGTA
  AGCCTCCTTGTATTGAGATAATTGGGCATTAAACATTAAACTGCAGCTCTGGGAAAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAC
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC007609 unedited
  AGCGTACAAAATTTGTATACGACTCACTATAGGCGGCCGCGAATTCGCACGAGGCTAGAA
  TGCTAATTGCACTTAGGCCTCATGGTTCTAGTAAACGGCAGCTGTGGGCCCTTTTGCCTC
  TTCCCCTGTTCTTGGCCTCACATCTCCAGCTGAGCTGCCGGTCTTGGCTTCCTGGTCGCC
  TCTGTCCCAGAGATGGTCCCAGGGAGCCATCCTAGGGCAGGTAGCACTGAGGCTCCTGTG
  GAAACAGGAGCCACCTGCTCAGGAGACCCCTTTCCTGAGGAAGTCCTTACCTCTCCCCTT
  GAGATGTAAAAATGGTCCAGCAGAGACAAGCTCCCGTGGAAAACAGACAGGAGCATGGGG
  GCAGCTGTCATGGCTGTGGCGGGCACTTTTCCTCAGAGTTTCTGCCTTGCGCTGGTCCAG
  GAGCCATTTTGCACCAAGGACTTGGTAGGCAGAGGCAGCCCCACTGTAAAGAAGGGTCAG
  ATTAAAACAAAAAACTGCCAAAAGCATCCCCTCTGCCCCCCATGTGGCACTGGCATCATT
  CTCTGCTTCCCTGGGAGGAATTTTTTCACCATGTTATTGAAGGGGATGGTTCATTAAGGA
  CTCCACCCCTCAGAGCTCACTCAGACCCCAAGGACAGAGGTGACTGGGGCTTGGTGACTT
  GTTCACTCCTTTTTTCCCCAGTATACTGAANGGGTGACAGAGAGAGGTCTTCATGGCAGA
  CCAGGCCTTCACAGCTAATGGGGAGAGGAACTCATGTTACCTCTGCAGGCCTGGGGTCCC
  TGAGGGGTCTTTTGGCTTCAGCCTGTTCCCCCAGAAGCTTGATCATCCCACATTGTCCCT
  TCAGCTCAGCTGCTCTTCTTCCCCACCCACCCTGGGATGGTGGTGCTCTGGGCCTGACCC
  AAGCTATGACTTCTG
  
• Restriction Sites: Please inquire
• ACCN: BC007609
• Insert Size: 2917
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC007609.1, AAH07609.1
• RefSeq Size: 2917
• Locus ID: 1870
• Protein Families: Druggable Genome, Transcription Factors
• Protein Pathways: Bladder cancer, Cell cycle, Chronic myeloid leukemia, Glioma, Melanoma, Non-small cell lung cancer, Pancreatic cancer, Pathways in cancer, Prostate cancer, Small cell lung cancer
• Gene Summary: The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F1 and E2F3, have an additional cyclin binding domain. This protein binds specifically to retinoblastoma protein pRB in a cell-cycle dependent manner, and it exhibits overall 46% amino acid identity to E2F1. [provided by RefSeq, Jul 2008]