TSLP (BC016720) Human Untagged Clone

CAT#: SC122435

TSLP (untagged)-Homo sapiens, Similar to thymic stromal lymphopoietin, clone MGC:24434 IMAGE:4074772, complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: TSLP
• Synonyms: thymic stromal lymphopoietin
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_138551 edited
  GGGGGACTCTCGACTTGTGTTCCCCGCTCCTCCCTGACCTTCCTCCCCTCCCCTTTCACT
  CAATTCTCACCAACTCTTTCTCTCTCTGGTGTTTTCTCCTTTTCTCGTAAACTTTGCCGC
  CTATGAGCAGCCACATTGCCTTACTGAAATCCAGAGCCTAACCTTCAATCCCACCGCCGG
  CTGCGCGTCGCTCGCCAAAGAAATGTTCGCCATGAAAACTAAGGCTGCCTTAGCTATCTG
  GTGCCCAGGCTATTCGGAAACTCAGATAAATGCTACTCAGGCAATGAAGAAGAGGAGAAA
  AAGGAAAGTCACAACCAATAAATGTCTGGAACAAGTGTCACAATTACAAGGATTGTGGCG
  TCGCTTCAATCGACCTTTACTGAAACAACAGTAAACCATCTTTATTATGGTCATATTTCA
  CAGCACCAAAATAAATCATCTTTATTAAGTAGATGAAACATTAACTCTAACTGTGACAAA
  GAAGACCACAAATAGTTATCTTTTAATTACAGAAGAGTTTCTTAACTTACTTTTGTAAGT
  TTTTATTGTGTAAGTTTATAATGCAGGGGAAGTACTACTCCTCAAATGTTGAGGGAAGCT
  TCCATAACATTGATGACTGGCTTCATGGCAGTAATTCTCGGCTGTAGTTGCATAAGCATT
  GCTCAAGAGGAAAATCCAAAAGTGCAGCAGGAGAACTTTTTTCCCTGAAAAAGGAAAAAT
  ATTGAACTCAATGATAGCACCTAAACTTACATTTAAAAGACAGACATTCCTTCTACATGT
  AATGACACTTCTTGTGTTAAACTAAAAATTTACAAGAGAAGAAAGTGAAAGCAAATGGGG
  TTTCACAAATAGTTGTAAATATAGTGAAGCAATTTGAAATAATTTTCAAGCAAAGTATTG
  TGAAAGTATTCTAAGCCAAGTTTTAAATATTATCTAACAGACAAGAGTGGTATATACAAG
  TAGATCCTGAGAAGTACCTTTGTTACAGCTACTATAAATATACATATAAATTATAGAATC
  TACTTTAATTTATTTTGTGAACACTTTTGAAAATGTACATGTTCCTTTGTAATTGACACT
  ATATATTTCTTAATAAAATAATTCCCAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC016720 unedited
  GGGGGTTAGGATTTGTNATACGACTTCACTATAGGGCGGCCGCGAATTCGCCATTACGGC
  CGGGGGACTCTCGACTTGTGTTCCCCGCTCCTCCCTGACCTTCCTCCCCTCCCCTTTCAC
  TCAATTCTCACCAACTCTTTCTCTCTCTGGTGTTTTCTCCTTTTCTCGTAAACTTTGCCG
  CCTATGAGCAGCCACATTGCCTTACTGAAATCCAGAGCCTAACCTTCAATCCCACCGCCG
  GCTGCGCGTCGCTCGCCAAAGAAATGTTCGCCATGAAAACTAAGGCTGCCTTAGCTATCT
  GGTGCCCAGGCTATTCGGAAACTCAGATAAATGCTACTCAGGCAATGAAGAAGAGGAGAA
  AAAGGAAAGTCACAACCAATAAATGTCTGGAACAAGTGTCACAATTACAAGGATTGTGGC
  GTCGCTTCAATCGACCTTTACTGAAACAACAGTAAACCATCTTTATTATGGTCATATTTC
  ACAGCACCAAAATAAATCATCTTTATTAAGTAGATGAAACATTAACTCTAACTGTGACAA
  AGAAGACCACAAATAGTTATCTTTTAATTACAGAAGAGTTTCTTAACTTACTTTTGTAAG
  TTTTTATTGTGTAAGTTTATAATGCAGGGGAAGTACTACTCCTCNANATGTGAGGGAAGC
  TTCCCATACATTGATGACTGGCTTCATGGCAGTAATTCTCGGCTGTAGTTGCATAAGCAT
  TGCTCAAGAGGAAAATCCAANAGTGCAGCAGNGAGACCTTTTTTCCCTGGAAAAGGGNAA
  AATATTGNAGCTCATGATAGCACCTAAACTTACATTNTAAAGAAGACATTCCTCTACATG
  TAATGACACTTTCTGGGTTAAACTAAAAATTACAAGAAAGAAAGTGAAGCCAATGGGGTT
  CACCAAATGTTT
  
• Restriction Sites: Please inquire
• ACCN: BC016720
• Insert Size: 1100
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• OTI Annotation: This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA.

Reference Data

• RefSeq: BC016720.1, AAH16720.1
• RefSeq Size: 1135
• Locus ID: 85480
• Protein Families: Druggable Genome
• Protein Pathways: Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
• Gene Summary: This gene encodes a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jan 2012]