VPREB3 (NM_013378) Human Untagged Clone

CAT#: SC122793

VPREB3 (untagged)-Human pre-B lymphocyte 3 (VPREB3)

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: VPREB3
• Synonyms: 8HS20; N27C7-2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_013378 edited
  GCATGCTCTGTTGTGGTCCAGTGGCCTTCCCAGCCCTGTGCCCCAAAGCACCTGGAGCAT
  ATAGCCTTGCAGAACTTCTACTTGCCTGCCTCCCTGCCTCTGGCCATGGCCTGCCGGTGC
  CTCAGCTTCCTTCTGATGGGGACCTTCCTGTCAGTTTCCCAGACAGTCCTGGCCCAGCTG
  GATGCACTGCTGGTCTTCCCAGGCCAAGTGGCTCAACTCTCCTGCACGCTCAGCCCCCAG
  CACGTCACCATCAGGGACTACGGTGTGTCCTGGTACCAGCAGCGGGCAGGCAGTGCCCCT
  CGATATCTCCTCTACTACCGCTCGGAGGAGGATCACCACCGGCCTGCTGACATCCCCGAT
  CGATTCTCGGCAGCCAAGGATGAGGCCCACAATGCCTGTGTCCTCACCATTAGTCCCGTG
  CAGCCTGAAGACGACGCGGATTACTACTGCTCTGTTGGCTACGGCTTTAGTCCCTAGGGG
  TGGGGTGTGAGATGGGTGCCTCCCCTCTGCCTCCCATTTCTGCCCCTGACCTTGGGTCCC
  TTTTAAACTTTCTCTGAGCCTTGCTTCCCCTCTGTAAAATGGGTTAATAATATTCAACAT
  GTCAACAACAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_013378 unedited
  NNNNGAAGCGTACAGAATTGTATACGACTCACTATAGGCGGCCGCGAATCGGCCATTACG
  GCCGGGGGCATGCTCTGTTGTGGTCCAGTGGCCTTCCCAGCCCTGTGCCCCAAACACCTG
  GAGCATATAGCCTTGCAGAACTTCTACTTGCCTGCCTCCCTGCCTCTGGCCATGGCCTGC
  CGGTGCCTCAGCTTCCTTCTGATGGGGACCTTCCTGTCAGTTTCCCAGACAGTCCTGGCC
  CAGCTGGATGCACTGCTGGTCTTCCCAGGCCAAGTGGCTCAACTCTCCTGCACGCTCAGC
  CCCCAGCACGTCACCATCAGGGACTACGGTGTGTCCTGGTACCAGCAGCGGGCAGGCAGT
  GCCCCTCGATATCTCCTCTACTACCGCTCGGAGGAGGATCACCACCGGCCTGCTGACATC
  CCCGATCGATTCTCGGCAGCCAAGGATGAGGCCCACAATGCCTGTGTCCTCACCATTAGT
  CCCGTGCAGCCTGAAGACGACGCGGATTACTACTGCTCTGTTGGCTACGGCTTTAGTCCC
  TAGGGGTGGGGTGTGAGAATGGGTGCCTCCCCTCTGCCTCCCATTTCTGCCCCTGACCTT
  GGGTCCCTTTTAAACTTTCTCTGAGCCTTGCTTCCCCTCTGTAAAATGGGTTAATAATAT
  TCAACATGTCAACAACNNNNNANAANAANNNAAANNAAAAAAAACATGTCGGCCGCCTCG
  GCCCTCGACTCTAGATTGCGGCCGCGGTCATAGCTGTTTCCTGACAGATCCCGGGTGGCA
  TCCCTGTGACCCCTCCCAATGCCTCTCCTGGCCCTGGAAGTTGCACTCCAGTGCCCACCA
  GCCCTGTCCAAAAAAATAAGTTGCATATTTTGGCTGACAAGGTGTCCTCT
  
• Restriction Sites: Please inquire
• ACCN: NM_013378
• ORF Size: 372 bp
• Insert Size: 637
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_013378.1, NP_037510.1
• RefSeq Size: 548
• RefSeq ORF: 372
• Locus ID: 29802
• Protein Families: Druggable Genome
• Gene Summary: The protein encoded by this gene is the human ortholog of the mouse VpreB3 (8HS20) protein, is thought to be involved in B-cell maturation, and may play a role in assembly of the pre-B cell receptor (pre-BCR). While the role of this protein in B-cell development has not yet been elucidated, studies with the chicken ortholog of this protein have found that when overexpressed, this protein localizes to the endoplasmic reticulum. The mouse ortholog of this protein has been shown to associate with membrane mu heavy chains early in the course of pre-B cell receptor biosynthesis. Expression of this gene has been observed in some lymphomas. [provided by RefSeq, Apr 2015]