EME1 (NM_152463) Human Untagged Clone

CAT#: SC123252

EME1 (untagged)-Human essential meiotic endonuclease 1 homolog 1 (S. pombe) (EME1), transcript variant 2

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: EME1
• Synonyms: MMS4L; SLX2A
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for NM_152463 edited
  GGGAATTATTTGATAGCACATACTGATGGCTCTAAAGAAGTCATCACCCTCACTGGATTC
  TGGTGATAGTGACTCTGAGGAGTTGCCAACATTTGCCTTTCTGAAGAAGGAACCATCTTC
  AACAAAGAGGAGACAGCCTGAAAGGGAAGAGAAGATTGTAGTGGTTGACATCTCAGATTG
  TGAAGCCTCCTGTCCTCCAGCACCAGAGTTATTTTCACCACCTGTCCCAGACATAGCTGA
  AACTGTCACACAAACACAGCCAGTCAGGTTGCTAAGCAGTGAAAGTGAAGATGAAGAAGA
  ATTTATTCCTCTGGCTCAAAGGCTTACATGTAAGTTTCTGACCCACAAGCAACTGAGCCC
  TGAGGACTCTAGCTCCCCAGTTAAAAGTGTTTTGGATCATCAAAATAATGAAGGTGCATC
  ATGTGACTGGAAAAAGCCCTTTCCAAAGATCCCTGAAGTTCCCCTCCATGATACCCCAGA
  GAGGAGTGCAGCAGATAACAAGGACCTGATCTTAGATCCATGCTGTCAGCTTCCAGCCTA
  CCTGTCTACCTGCCCTGGCCAGAGCAGCAGCTTGGCAGTAACCAAAACAAATTCTGACAT
  CCTTCCACCCCAGAAGAAAACCAAGCCGAGTCAGAAGGTCCAGGGAAGAGGCTCACACGG
  ATGCCGGCAGCAGAGACAAGCAAGGCAGAAGGAAAGCACCCTGAGAAGACAGGAAAGAAA
  GAATGCAGCACTGGTTACCAGGATGAAAGCCCAGAGGCCAGAGGAATGCTTAAAACACAT
  CATTGTAGTGCTGGATCCAGTGCTCTTACAGATGGAAGGTGGGGGCCAGCTCCTAGGAGC
  ACTGCAGACCATGGAGTGCCGCTGTGTGATTGAGGCGCAGGCTGTGCCTTGCAGTGTCAC
  TTGGAGGAGAAGGGCTGGGCCGTCTGAGGACAGAGAGGACTGGGTGGAGGAGCCAACAGT
  ACTGGTGTTGCTCCGGGCAGAGGCATTTGTGTCCATGATCGACAATGGAAAGCAGGGAAG
  CCTGGACAGCACTATGAAAGGGAAGGAAACGCTTCAGGGCTTTGTAACTGACATCACAGC
  AAAGACAGCAGGGAAAGCTCTGTCACTGGTGATTGTGGATCAGGAGAAATGCTTCAGCCT
  GGAGCTGCTGTTCTTTGATTTCCTCCCCTGCACCAGTGCTCAGAATCCTCCAAGAAGAGG
  GAAACAGGGAGCAAATAAACAGACCAAGAAGCAGCAGCAGAGACAACCAGAGGCCAGCAT
  AGGGTCCATGGTATCCAGGGTAGACGCTGAAGAGGCATTGGTGGATCTGCAGCTACACAC
  AGAAGCCCAGGCTCAAATTGTGCAGAGCTGGAAAGAGCTGGCCGACTTCACATGCGCATT
  CACAAAGGCTGTGGCTGAGGCGCCCTTCAAGAAGCTCCGAGATGAAACTACCTTCTCCTT
  CTGTCTGGAGAGTGACTGGGCTGGAGGGGTGAAGGTGGACCTTGCTGGCAGGGGACTCGC
  ACTAGTCTGGAGGAGACAGATTCAGCAGCTGAACCGAGTCAGCCTGGAAATGGCCAGTGC
  AGTTGTGAATGCCTATCCCTCCCCACAGCTCCTGGTACAGGCTTATCAGCAGTGTTTTTC
  GGATAAAGAACGCCAGAATTTGCTCGCAGACATACAGGTGCGCCGTGGGGAAGGTGTGAC
  ATCCACTTCTCGCCGCATTGGACCAGAACTATCCAGGCGTATCTACCTTCAGATGACCAC
  TTTACAGCCACATCTCTCTTTAGATAGTGCTGACTGATTCTAGCCCTCAGGGATGAGGAT
  GAAAAGCTGGAAACTTCCACTTCCCCAACCTCAGAGCCTGACTGTAATGAAGAGACTGGC
  AGCACCTCCTGGAACACAAGCCTAGGTGAGGCCCAGTCTTTCTTGGGTCTTATTATTTGT
  GAAGGTCTCTCTGCCTGTCGGCTGGGGCAGAGACTGAAATACTGCCACCTACCTTTGGCA
  TTTAATGTTCCTCTCCTGGCAAAAATTCACTGCCACAGACAAACCACCCCCACTCCTACC
  CAGCCAGCCCTCAAAACACAAAGGAACAAAGACAGTCCACTCAGACACTTATTTAATAAC
  TGTAGAAATCCAAAAGAATTAGCATCAAATCTTGAAGTCGTGAGTGAAGCTGCGGGTTGG
  CTTGACTGGGCTCAGCCACTGAGCTGCCTCAACCGGCCAAGGAACGGGATTATGATGACT
  ATGCGGACTTCTATATTGTCTTCATCTCATTGTGTGTATTATGTATTTAGTTTCAATAAA
  GCATTTGTACCAATGGCAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_152463 unedited
  CATCTGGTTTTGTAATACCACTTCCTATAGGCGGCCGCGCATTCCCGGGATATCGTCGAC
  CCACGCGTCCGGGGNAGAAGTTGCAGGGAATTATTTGATAGCACATACTGATGGCTCTAA
  AGAAGTCATCACCCTCACTGGATTCTGGTGATAGTGACTCTGAGGAGTTGCCAACATTTG
  CCTTTCTGAAGAAGGAACCATCTTCAACAAAGAGGATACAGCCTGAAAGGGAAGAGAAGA
  TTGTAGTGGTTGACATCTCAGATTGTGAAGCCTCCTGTCCTCCAGCACCAGAGTTATTTT
  CACCACCTGTCCCAGACATAGCTGAAACTGTCACACAAACACAGCCAGTCAGGTTGCTAA
  GCAGTGAAAGTGAAGATGAAGAAGAATTTATTCCTCTGGCTCAAAGGCTTACATGTAAGT
  TTCTGACCCACAAGCAACTGAGCCCTGAGGACTCTAGCTCCCCAGTTAAAAGTGTTTTGG
  ATCATCAAAATAATGAAGGTGCATCATGTGACTGGAAAAAGCCCTTTCCAAAGATCCCTG
  AAGTTCCCCTCCATGATACCCCAGAGAGGAGTGCAGCAGATAACAAGGACCTGATCTTAG
  ATCCATGCTGTCAGCTTCCAGCCTACCTGTCTACCTGCCCTGGCCAGAGCAGCAGCTTGG
  CAGTAACCAAAACAAATTCTGACATCCTTCCACCCCAGGAGAAAACCAAGCCGAGTCAGA
  AAGTCCAGGGAAGAGGCTCACACGGATGCCGGCAGCAGAGACAAGCAAGGCAGATAGAAA
  GCACCCTGAGAAGACAGGAAAGAAAGTATGCAGCACTGGTTACCAGGATGAAAGCCCAGA
  GGCCAGAGGAATGCTNTAAACACATCATTGTAGTGCTANATCCAGTGCTNCTACGATGGG
  AAGTGGGGGCCAGCTNNCTAGACACTGCAG
  
• Restriction Sites: Please inquire
• ACCN: NM_152463
• ORF Size: 1713 bp
• Insert Size: 2327
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: NM_152463.1, NP_689676.1
• RefSeq Size: 2304
• RefSeq ORF: 1713
• Locus ID: 146956
• Protein Pathways: Homologous recombination
• Gene Summary: This gene encodes a protein that complexes with methyl methanesulfonate-sensitive UV-sensitive 81 protein to form an endonuclease complex. The encoded protein interacts with specifc DNA structures including nicked Holliday junctions, 3'-flap structures and aberrant replication fork structures. This protein may be involved in repairing DNA damage and in maintaining genomic stability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
  Transcript Variant: This variant (2) uses an alternate in-frame splice site in the coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.