Protein C (PROC) (BC034377) Human Untagged Clone

CAT#: SC123476

PROC (untagged)-Human protein C (inactivator of coagulation factors Va and VIIIa) (cDNA clone MGC:34565 IMAGE:5188604), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: PROC
• Synonyms: protein C
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC034377 edited
  CGGCGAACTTGCAGTATCTCCACGACCCGCCCCTACAGGTGCCAGTGCCTCCAGAATGTG
  GCAGCTCACAAGCCTCCTGCTGTTCGTGGCCACCTGGGGAATTTCCGGCACACCAGCTCC
  TCTTGACTCAGTGTTCTCCAGCAGCGAGCGTGCCCACCAGGTGCTGCGGATCCGCAAACG
  TGCCAACTCCTTCCTGGAGGAGCTCCGTCACAGCAGCCTGGAGCGGGAGTGCATAGAGGA
  GATCTGTGACTTCGAGGAGGCCAAGGAAATTTTCCAAAATGTGGATGACACACTGGCCTT
  CTGGTCCAAGCACGTCGACGGTGACCAGTGCTTGGTCTTGCCCTTGGAGCACCCGTGCGC
  CAGCCTGTGCTGCGGGCACGGCACGTGCATCGACGGCATCGGCAGCTTCAGCTGCGACTG
  CCGCAGCGGCTGGGAGGGCCGCTTCTGCCAGCGCGAGGTGAGCTTCCTCAATTGCTCTCT
  GGACAACGGCGGCTGCACGCATTACTGCCTAGAGGAGGTGGGCTGGCGGCGCTGTAGCTG
  TGCGCCTGGCTACAAGCTGGGGGACGACCTCCTGCAGTGTCACCCCGCAGTGAAGTTCCC
  TTGTGGGAGGCCCTGGAAGCGGATGGAGAAGAAGCGCAGTCACCTGAAACGAGACACAGA
  AGACCAAGAAGACCAAGTAGATCCGCGGCTCATTGATGGGAAGATGACCAGGCGGGGAGA
  CAGCCCCTGGCAGGTGGTCCTGCTGGACTCAAAGAAGAAGCTGGCCTGCGGGGCAGTGCT
  CATCCACCCCTCCTGGGTGCTGACAGCGGCCCACTGCATGGATGAGTCCAAGAAGCTCCT
  TGTCAGGCTTGGAGAGTATGACCTGCGGCGCTGGGAGAAGTGGGAGCTGGACCTGGACAT
  CAAGGAGGTCTTCGTCCACCCCAACTACAGCAAGAGCACCACCGACAATGACATCGCACT
  GCTGCACCTGGCCCAGCCCGCCACCCTCTCGCAGACCATAGTGCCCATCTGCCTCCCGGA
  CAGCGGCCTTGCAGAGCGCGAGCTCAATCAGGCCGGCCAGGAGACCCTCGTGACGGGCTG
  GGGCTACCACAGCAGCCGAGAGAAGGAGGCCAAGAGAAACCGCACCTTCGTCCTCAACTT
  CATCAAGATTCCCGTGGTCCCGCACAATGAGTGCAGCGAGGTCATGAGCAACATGGTGTC
  TGAGAACATGCTGTGTGCGGGCATCCTCGGGGACCGGCAGGATGCCTGCGAGGGCGACAG
  TGGGGGGCCCATGGTCGCCTCCTTCCACGGCACCTGGTTCCTGGTGGGCCTGGTGAGCTG
  GGGTGAGGGCTGTGGGCTCCTTCACAACTACGGCGTTTACACCAAAGTCAGCCGCTACCT
  CGACTGGATCCATGGGCACATCAGAGACAAGGAAGCCCCCCAGAAGAGCTGGGCACCTTA
  GCGACCCTCCCTGCAGGGCTGGGCTTTTGCATGGCAATGGATGGGACATTAAAGGGACAT
  GTAACAAGCACACCGGCCTGCTGTTCTGTCCTTCCATCCCTCTTTTGGGCTCTTCTGGAG
  GGAAGTAACATTTACTGAGCACCTGTTGTATGTCACATGCCTTATGAATAGAATCTTAAC
  TCCTAGAGCAACTCTGTGGGGTGGGGAGGAGCAGATCCAAGTTTTGCGGGGTCTAAAGCT
  GTGTGTGTTGAGGGGGATACTCTGTTTATGAAAAAGAATAAAAAACACAACCACGAAAAA
  AAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC034377 unedited
  CATATTTGTATACGACTCATATAGGCGGCCGCGAATTCCCGGGATCGGCGAATTTGCAGT
  ATCTCCACGACCCGCCCCTACAGGTGCCAGTGCCTCCAGAATGTGGCAGCTCACAAGCCT
  CCTGCTGTTCGTGGCCACCTGGGGAATTTCCGGCACACCAGCTCCTCTTGACTCAGTGTT
  CTCCAGCAGCGAGCGTGCCCACCAGGTGCTGCGGATCCGCAAACGTGCCAACTCCTTCCT
  GGAGGAGCTCCGTCACAGCAGCCTGGAGCGGGAGTGCATAGAGGAGATCTGTGACTTCGA
  GGAGGCCAAGGAAATTTTCCAAAATGTGGATGACACACTGGCCTTCTGGTCCAAGCACGT
  CGACGGTGACCAGTGCTTGGTCTTGCCCTTGGAGCACCCGTGCGCCAGCCTGTGCTGCGG
  GCACGGCACGTGCATCGACGGCATCGGCAGCTTCAGCTGCGACTGCCGCAGCGGCTGGGA
  GGGCCGCTTCTGCCAGCGCGAGGTGAGCTTCCTCAATTGCTCTCTGGACACGGCGGCTGC
  ACGCATTACTGCCTANAGGAGGTGGGCTGGCGGCGCTGTAGCTGTGCGCCTGGCTACAAG
  CTGGGGGACGACCCTCTGCAGTGTCACCCCGCAGTGAAAGTCCCTTTGTGGAGGCCCTGN
  NAGCGGATGGAGAAAAGCGCAGTCNCCTGAACGAGACNCAGAGACCCAGAGACCAGTGGA
  TCCGCGGCTATTGATGGAAAGATGACCCAGCGGGAGACAGCCCCTGCAGGTGGTCCTGCT
  GGACTCAAAGAAAAACTGCCCGCCGGGCAGTGCTCAATCACCCCTCCTGGTGCTGAAAGC
  GGCCACTGGATGGATGATTCAAAAACCTCCTGTCAGGCTTGGAAATATGACCTGCGCCCC
  TGGAAAATGGGACCTGACCTGGACAATAGGAGG
  
• Restriction Sites: Please inquire
• ACCN: BC034377
• Insert Size: 1792 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: BC034377.1, AAH34377.1
• RefSeq Size: 1792 bp
• Locus ID: 5624
• Cytogenetics: 2q14.3
• Protein Families: Druggable Genome, Protease
• Protein Pathways: Complement and coagulation cascades
• Gene Summary: 'This gene encodes a vitamin K-dependent plasma glycoprotein. The encoded protein is cleaved to its activated form by the thrombin-thrombomodulin complex. This activated form contains a serine protease domain and functions in degradation of the activated forms of coagulation factors V and VIII. Mutations in this gene have been associated with thrombophilia due to protein C deficiency, neonatal purpura fulminans, and recurrent venous thrombosis.[provided by RefSeq, Dec 2009]'