Neurotensin Receptor 2 (NTSR2) (BC022501) Human Untagged Clone

CAT#: SC123559

NTSR2 (untagged)-Human neurotensin receptor 2 (cDNA clone MGC:26447 IMAGE:4792730), complete cds

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: NTSR2
• Synonyms: levocabastine-sensitive neurotensin receptor; neurotensin receptor, type 2; neurotensin receptor 2; NTR2
• Vector: pCMV6-XL5
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >OriGene sequence for BC022501 edited
  AGTGAGAGGGAGGGAGCGCCGGCCGCGGGAGCGGGATGGAAACCAGCAGCCCGCGGCCCC
  CGCGGCCCAGCTCCAACCCGGGGCTGAGCCTGGACGCCCGGCTGGGCGTGGACACTCGCC
  TCTGGGCCAAGGTGCTGTTCACCGCGCTCTACGCACTCATCTGGGCGCTGGGCGCGGCGG
  GCAATGCGCTGTCCGTGCACGTGGTGCTGAAGGCGCGGGCCGGGCGAGCGGGGCGCCTGC
  GCCACCACGTGCTCAGCCTGGCGCTCGCGGGCCTGCTGCTGCTGCTGGTCGGCGTGCCGG
  TGGAGCTCTACAGCTTCGTGTGGTTCCACTACCCCTGGGTCTTCGGCGACCTGGGCTGCC
  GCGGCTACTACTTCGTGCACGAGCTGTGCGCCTACGCCACGGTGCTGAGCGTGGCAGGCC
  TGAGCGCCGAGCGCTGCCTAGCCGTGTGCCAGCCCCTGCGTGCCCGCAGCCTGCTGACGC
  CACGCCGGACCCGGTGGCTGGTGGCGCTCTCGTGGGCCGCCTCGCTCGGCCTCGCCATGC
  CCATGGCCGTCATCATGGGGCAGAAGCACGAACTCGAGACGGCGGACGGGGAGCCGGAGC
  CCGCCTCGCGAGTGTGCACGGTGCTGGTGAGCCGCACCGCGCTCCAAGTCTTTATCCAGG
  TGAATGTGCTGGTGTCCTTCGTGCTCCCCTTGGCACTAACTGCTTTCCTGAATGGGGTCA
  CAGTGAGCCACCTGCTGGCCCTCTGCTCCCAAGTGCCGTCCACTTCTACCCCGGGCAGCT
  CCACCCCCAGCCGCCTGGAGCTGCTGAGTGAGGAGGGTCTCCTCAGCTTCATCGTATGGA
  AGAAGACCTTTATCCAGGGAGGCCAGGTCAGCCTGGTGAGACATAAAGACGTGCGCCGGA
  TCCGCAGCCTCCAGCGCAGCGTCCAGGTTCTCAGAGCCATCGTGGTCATGTATGTCATCT
  GCTGGCTGCCGTACCATGCCCGCAGGCTCATGTACTGCTACGTACCTGATGACGCGTGGA
  CTGACCCACTGTACAATTTCTACCACTACTTCTACATGGTGACCAACACACTTTTCTACG
  TCAGCTCAGCTGTGACTCCTCTTCTCTACAACGCCGTGTCCTCCTCCTTCAGAAGACTCT
  TCCTGGAAGCCGTCAGCTCCCTGTGTGGAGAGCACCACCCCATGAAGCGGTTACCCCCGA
  AGCCCCAGAGTCCCACCCTAATGGATACAGCTTCAGGCTTTGGGGATCCCCCAGAAACCC
  GGACCTGAATGTAATGCAAGAATGAACAGAACAAGCAAAATGACCAGCTGCTTAGTCACC
  TGGCAAAGCAGGTGAGCAACCTCATCACTAATCATTCAAGCTTCGCAGCCAGGGCGACTT
  CTATCAACCCCTGCTCTGCTGAGAACCATCAAGCGCAGGGAAGCCACGTGACCCCTCCTA
  GCCTCAGGCTCCCTCGTCTGTGTAGTGGAGATAAAGAACAGCACCCATCTCTTAGTGTTG
  CCTGAGACTAAAGTGCTTAGCACAGAACCTGGTGCGTAGTAGATGCTCAATAAATTTTTG
  CTGGCACAAAAAAAAAAAAAAAA
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for BC022501 unedited
  GCTCAGGTTTNGTAAACGACTTCGCTATAGGCGGCCGCACAACTTCGTATAGCATACATT
  ATACGAAGTTATGGATCAGGCCAAATCGGCCGAGCTCGAATTCGTCGAGAGCGGAGTGAG
  AGGGAGGGAGCGCCGGCCGCGGGAGCGGGATGGAAACCAGCAGCCCGCGGCCCCCGCGGC
  CCAGCTCCAACCCGGGGCTGAGCCTGGACGCCCGGTTGGGCGTGGACACTCGCCTCTGGG
  CCAAGGTGCTGTTCACCGCGCTCTACGCACTCATCTGGGCGCTGGGCGCGGCGGGCAATG
  CGCTGTCCGTGCACGTGGTGCTGAAGGCGCGGGCCGGGCGAGCGGGGCGCCTGCGCCACC
  ACGTGCTCAGCCTGGCGCTCGCGGGCCTGCTGCTGCTGCTGGTCGGCGTGCCGGTGGAGC
  TCTACAGCTTCGTGTGGTTCCACTACCCCTGGGTCTTCGGCGACCTGGGCTGCCGCGGCT
  ACTACTTCGTGCACGAGCTGTGCGCCTACGCCACGGTGCTGAGCGTGGCAGGCCTGAGCG
  CCGAGCGCTGCCTAGCCGTGTGCCAGCCCCTGCGTGCCCGCAGCCTGCTGACGCCACGCC
  GGACCCGGTGGCTGGTGGCGCTCTCGTGGGCCGCCTCGCTCGGCCTCGCCATGCCCATGG
  GCCGTCATCATGGGGCAGAAGCACGAACTCGAGACGGCGGACGGGGAGCCGGAGCCCGCC
  TCGCGAGTGTGCACGGTGCTGGTGAGCCGCACCGCGCTTCAAGTCTNTATCCCAGTGAAT
  GTGCTAGTGGTCTTCGTGCTCCCCTGGGACTAACTGGCTTTCTTGAAGGGGGACCAGGAG
  CCACCTGGTGGGCCTCTGTTCCAAGGGCCGGCCCTTTTTACCCCGGGGATTCCCCCCCCA
  GCCGCCTGAGCTGCTGATGAAGGAG
  
• Restriction Sites: Please inquire
• ACCN: BC022501
• ORF Size: 1230 bp
• Insert Size: 1583
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).

Reference Data

• RefSeq: BC022501.1, AAH22501.1
• RefSeq Size: 1583
• RefSeq ORF: 1230
• Locus ID: 23620
• Protein Families: Druggable Genome, GPCR, Transmembrane
• Protein Pathways: Neuroactive ligand-receptor interaction
• Gene Summary: The protein encoded by this gene belongs to the G protein-coupled receptor family that activate a phosphatidylinositol-calcium second messenger system. Binding and pharmacological studies demonstrate that this receptor binds neurotensin as well as several other ligands already described for neurotensin NT1 receptor. However, unlike NT1 receptor, this gene recognizes, with high affinity, levocabastine, a histamine H1 receptor antagonist previously shown to compete with neurotensin for low-affinity binding sites in brain. These activities suggest that this receptor may be of physiological importance and that a natural agonist for the receptor may exist. [provided by RefSeq, Jul 2008]