SCN4B (NM_174934) Human Untagged Clone

CAT#: SC123982

SCN4B (untagged)-Human sodium channel, voltage-gated, type IV, beta (SCN4B), transcript variant 1


  "NM_174934" in other vectors (6)

Reconstitution Protocol

USD 420.00

In Stock*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SCN4B
Synonyms ATFB17; LQT10; Navbeta4
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>OriGene ORF within SC324716 sequence for NM_001142349 edited (data generated by NextGen Sequencing)


ATGAACAACATTTCCATTGTGCTGAGGGACCTGGAGTTCAGCGACACGGGCAAATACACCTGCCATGTGA
AGAACCCCAAGGAGAATAATCTCCAGCACCACGCCACCATCTTCCTCCAAGTCGTTGATAGACTGGAAGA
AGTGGACAACACAGTGACACTCATCATCCTGGCTGTCGTGGGCGGGGTCATCGGGCTCCTCATCCTCATC
CTGCTGATCAAGAAACTCATCATCTTCATCCTGAAGAAGACTCGGGAGAAGAAGAAGGAGTGTCTCGTGA
GCTCCTCGGGGAATGACAACACGGAGAACGGCTTGCCTGGCTCCAAGGCAGAGGAGAAACCACCTTCAAA
AGTGTGA


Clone variation with respect to NM_001142349.1
>OriGene 5' read for NM_174934 unedited
TGTAATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCGCAAAGCTTCAGGGTA
GCTTTGTGGCCGAACGCCGACCTCGGGCGGAGAGCGCGGCTGTGCCCAGTATCCCATCCC
CGCGACCCCCGCGCGCTCCGGAGAGAACAGGACTATGCCCGGGGCTGGGGACGGAGGCAA
AGCCCCGGCGAGATGGCTGGGCACTGGGCTTTTGGGCCTCTTCCTGCTCCCCGTAACCCT
GTCGCTGGAGGTGTCTGTGGGAAAGGCCACCGACATCTACGCTGTCAATGGCACGGAGAT
CCTGCTGCCCTGCACCTTCTCCAGCTGCTTTGGCTTCGAGGACCTCCACTTCCGGTGGAC
CTACAACAGCAGTGACGCATTCAAGATTCTCATAGAGGGGACTGTGAAGAATGATAAGTC
TGACCCCAAGGTGACGTTGAAAGACGATGACCGCATCACTCTGGTAGGCTCTACTAAGGA
GAAGATGAACAACATTTCCATTGTGCTGAGGGACCTGGAGTTCAGCGACACGGGCAAATA
CACCTGCCATGTGAAGAACCNCAAGGAGAATAATCTCCAGCACCACGCCACCATCTATCT
CCAAGTCGTTGATAGACTGGAAGAAGTGGACAACACAGTGACACTCATCAATCCTGGCTG
TCGTGGGCAGGGTCATCGGGGGCTCTAATCCTCATCCTGCTGATCAAGAAACTTATTAAT
CTTCATCCTTGAGAATACATCGGAGAAAAAAAAAAGGAGGGCTCTGGGACCTTCTTGGGG
GAATGACCACCCGGAAAACGCGT
>OriGene 3' read for NM_174934 unedited
TATACAGTTTGANGCCAGCAGCAGATGTCTCAGGCACGTGGGTTCTACNGTCNGAGCTCA
AGCATCAGTTTCATCATCAGAAAGGGGGCTCCCTGCAGCTGCTCAGCCCGAAGCAGGGCT
CACACTTTTGAAGGTGGTTTCTCCTCTGCCTTGGAGCCAGGCAAGCCGTTCTCCGTGTTG
TCATTCCCCGAGGAGCTCACGAGACACTCCTTCTTCTTCTCCCGAGTCTTCTTCAGGATG
AAGATGATGAGTTTCTTGATCAGCAGGATGAGGATGAGGAGCCCGATGACCCCGCCCACG
ACAGCCAGGATGATGAGTGTCACTGTGTTGTCCACTTCTTCCAGTCTATCAACGACTTGG
AGGAAGATGGTGGCGTGGTGCTGGAGATTATTCTCCTTGGGGTTCTTCACATGGCAGGTG
TATTTGCCCGTGTCGCTGAACTCCAGGTCCCTCAGCACAATGGAAATGTTGTTCATCTTC
TCCTTAGTAGAGCCTACCAGAGTGATGCGGTCATCGTCTTTCAACGTCACCTTGGGGTCA
GACTTCTCATTCTTCACAGTCCCCTCTATGAGAATCTTGAATGCGTCACTGCTGTTGTAG
GTCCACCGGAAGTGGAGGTCCTCGAAGCCAAAGCAGCTGGAGAAGGTGCAGGGCAGCAGG
ATCTCCGTGCCATTGACAGCGTAGATGTCGGTGGCCTTTCCACAGACACCTNCAGCGACA
GGGTTACCGGGAGCAGGAAGAGGCCCAAAAACCCAGTGCCCACCATCTCGNCNGGGCTTT
GNNCTCGTCCAGN
Restriction Sites Please inquire     
ACCN NM_174934
Insert Size 4700 bp
OTI Disclaimer Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery.

The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
Reconstitution 1. Centrifuge at 5,000xg for 5min.
2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
3. Close the tube and incubate for 10 minutes at room temperature.
4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.
Reference Data
RefSeq NM_174934.1, NP_777594.1
RefSeq Size 4489 bp
RefSeq ORF 687 bp
Locus ID 6330
Cytogenetics 11q23.3
Protein Families Ion Channels: Sodium, Transmembrane
Gene Summary 'The protein encoded by this gene is one of several sodium channel beta subunits. These subunits interact with voltage-gated alpha subunits to change sodium channel kinetics. The encoded transmembrane protein forms interchain disulfide bonds with SCN2A. Defects in this gene are a cause of long QT syndrome type 10 (LQT10). Three protein-coding and one non-coding transcript variant have been found for this gene.[provided by RefSeq, Mar 2009]'
Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).

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