RFX2 (NM_000635) Human Untagged Clone

CAT#: SC124095

RFX2 (untagged)-Human regulatory factor X, 2 (influences HLA class II expression) (RFX2), transcript variant 1

Specifications

Product Data

• Type: Human Untagged Clone
• Tag: Tag Free
• Symbol: RFX2
• Vector: pCMV6-XL4
• E. coli Selection: Ampicillin (100 ug/mL)
• Mammalian Cell Selection: None
• Sequence Data:
  Fully Sequenced ORF

  >NCBI ORF sequence for NM_000635, the custom clone sequence may differ by one or more nucleotides
  
  
  ATGCAGAATTCCGAGGGTGGAGCGGATTCGCCAGCGTCCGTGGCTCTGCGTCCCTCGGCGGCAGCCCCGC
  CTGTGCCAGCCTCCCCGCAGAGGGTGTTGGTCCAGGCAGCCAGCTCCAATCCCAAAGGGGCCCAGATGCA
  GCCGATCTCCCTCCCCAGAGTTCAGCAGGTACCCCAGCAGGTGCAGCCGGTGCAGCACGTGTATCCTGCC
  CAGGTGCAGTACGTGGAAGGGGGAGACGCCGTCTACACCAATGGAGCCATACGAACAGCCTACACCTACA
  ACCCCGAGCCTCAGATGTACGCCCCCAGCAGCACGGCTTCTTACTTCGAGGCCCCAGGCGGTGCCCAGGT
  GACCGTGGCAGCCTCGTCCCCGCCAGCGGTCCCCTCCCACAGCATGGTGGGCATCACCATGGATGTCGGG
  GGGAGCCCCATCGTCTCCAGCGCGGGAGCCTATCTCATCCACGGGGGGATGGACAGCACCAGACACTCCC
  TGGCCCACACCTCCCGCTCATCGCCCGCCACGCTTGAAATGGCGATTGAAAACCTCCAAAAAAGCGAAGG
  AATCACATCACACAAAAGCGGTTTACTCAACAGCCATCTCCAGTGGCTGTTGGATAATTATGAAACAGCG
  GAAGGTGTGAGTCTCCCCAGAAGTTCTCTTTACAACCACTACCTTCGGCACTGCCAGGAGCACAAGCTAG
  ACCCAGTGAACGCCGCCTCCTTCGGGAAACTGATCCGTTCTGTGTTTATGGGGCTGAGAACGCGGCGGCT
  GGGCACCAGGGGCAACTCGAAGTACCATTACTATGGGATTCGTCTGAAGCCGGACTCACCACTGAACCGG
  CTGCAGGAGGACACGCAGTACATGGCCATGCGGCAGCAGCCCATGCACCAGAAGCCCAGGTACCGGCCAG
  CCCAGAAGACGGACAGCCTCGGGGACAGCGGCTCCCACAGCGGCCTGCACAGCACTCCGGAACAGACCAT
  GGCCGTGCAGAGCCAGCACCACCAGCAGTACATAGATGTCTCCCACGTCTTCCCCGAGTTCCCAGCGCCC
  GACCTGGGCAGCTTCCTGCTGCAGGACGGCGTCACACTGCACGACGTCAAGGCCCTGCAGCTGGTGTACA
  GACGGCACTGCGAGGCAACTGTAGATGTGGTGATGAACCTCCAGTTCCACTACATCGAGAAGCTGTGGCT
  CTCCTTCTGGAACTCTAAGGCCTCCTCCAGCGACGGCCCCACCTCTCTTCCTGCCAGTGACGAAGACCCC
  GAGGGCGCCGTCCTGCCCAAGGACAAGCTTATCTCCCTGTGTCAGTGCGACCCCATCCTCAGGTGGATGA
  GGAGCTGCGACCACATCCTCTACCAGGCGCTGGTGGAGATTCTCATCCCCGACGTGCTGAGGCCGGTCCC
  CAGTACCTTGACACAGGCCATCCGTAACTTTGCCAAGAGCTTGGAAGGCTGGTTGACAAATGCCATGAGT
  GACTTCCCACAACAGGTCATCCAGACCAAGGTGGGCGTCGTCAGTGCCTTCGCCCAGACGCTGCGGCGCT
  ACACGTCCCTCAACCACCTGGCGCAGGCGGCCCGGGCGGTGCTGCAGAACACGTCCCAGATCAACCAGAT
  GCTCAGCGACCTCAACCGCGTGGACTTTGCCAACGTGCAGGAGCAGGCCTCGTGGGTGTGCCAGTGCGAG
  GAGAGTGTGGTGCAGCGGCTGGAGCAGGATTTCAAGCTGACCCTGCAGCAGCAGAGCTCCCTGGACCAGT
  GGGCCAGCTGGCTGGACAGTGTGGTCACCCAGGTCCTGAAGCAGCATGCCGGCAGCCCCAGCTTCCCCAA
  GGCCGCCCGGCAGTTCTTGCTGAAATGGTCCTTTTACAGCTCCATGGTGATCCGGGACCTGACCCTGCGC
  AGCGCTGCCAGCTTCGGCTCCTTCCACCTCATCCGCCTGCTCTACGACGAGTACATGTTCTACCTGGTGG
  AGCACCGCGTCGCGGAGGCCACCGGAGAGACGCCGATCGCTGTGATGGGAGAGTTCAACGATCTCGCCTC
  TCTGTCGCTGACGCTGCTCGACAAAGATGACATGGGCGATGAGCAGCGTGGCAGCGAGGCGGGCCCAGAC
  GCCCGCAGCCTGGGTGAGCCCCTGGTAAAGCGGGAGCGCAGTGACCCCAACCACTCCCTGCAGGGCATCT
  AG
  
  
  5' Read Nucleotide Sequence

  >OriGene 5' read for NM_000635 unedited
  TAACGTCAGATTTTGTATACGACTCACTATAGGGCGGCCGCGAATTCGGCACGAGCTTAC
  CAACGGGGACCAACACGCAGCAGCCGCTGCCGCCGCCGCGGGAGCCGCTGCCCGAACTCC
  CGGCCCGAACTCCAGACCTGAGCATGCAGAATTCCGAGGGTGGAGCGGATTCGCCAGCGT
  CCGTGGCTCTGCGTCCCTCGGCGGCAGCCCCGCCTGTGCCAGCCTCCCCGCAGAGGGTGT
  TGGTCCAGGCAGCCAGCTCCAATCCCAAAGGGGCCCAGATGCAGCCGATCTCCCTCCCCA
  GAGTTCAGCAGGTACCCCAGCAGGTGCAGCCGGTGCAGCACGTGTATCCTGCCCAGGTGC
  AGTACGTGGAAGGGGGAGACGCCGTCTACACCAATGGAGCCATACGAACAGCCTACACCT
  ACAACCCCGAGCCTCAGATGTACGCCCCCAGCAGCACGGCTTCTTACTTCGAGGCCCCAG
  GCGGTGCCCAGGTGACCGTGGCAGCCTCGTCCCCGCCAGCGGTCCCCTCCCACAGCATGG
  TGGGCATCACCATGGATGTCGGGGGGAGCCCCATCGTCTCCAGCGCGGGAGCCTATCTCA
  TCCACGGGGGGGATGGACAGCACCAGACACTCCCTGGCCCACACCTCCCGCTCATCGCCC
  GGCACGCTTGAAATGGCGATTGAAAACCTCCAAAAAAAGCGAAGGAATCACATCACACAA
  AAGCGGTTTACTCAACAGCCATCTCCGGTGGCTGTTGNATAATTATGAACCAGCGGAGGT
  GTGAGTCTCCCCAGAAGTTCTTTTTACAACCCTTACCTTGGCACTGCCAGGAGCCCAGCT
  TAACCCAGGGACCCCGCCTCTTTGGGGAACTGATCCCGTTCTGTGTT
  
  3' Read Nucleotide Sequence

  >OriGene 3' read for NM_000635 unedited
  GGTATAGCACTGGGGAGGGGTCACAGGGATGCCACCCGGGATCTGTTCAGGAAACAGCTA
  TGACTTTTGCCGCAATCTATAGTCNAGACGTTTTTTTTGTTTTTTTTTTATACTGCAATG
  TACACATTCATAAGAAACGTTCTAATAACAATTAGCGCACAAAACTATTGGTATAAACAT
  TTTTCCAAAAAGAGAAAACTATTGCATTTCGTTAGAAATCGCGTCCTGGGCCGAGGCTCG
  TCTTTCTTCTCTGCAGTTGGTTTGGGGACAGAACTCCAGCACGCAGCTGTCCAACTGCAG
  CGGCTACGTGTTTCCATGGAGACAAACTTGGTGTCTCAAGTTCAGGGCTTCGAAAGTCCC
  GAATATTTGTTTGTCCCGAGAGAAGAGTTTTGACTTTGAAGAGGTCCAGGTGGGACTCGC
  TGGGGGTGGGGTGCTCCGGGATTAGTTCAGAGGGAGGTGTTCTGGAAGACTCCGTGGAGC
  GGGACGCAGGCACTGCTGTTTGGACGACACGCGGGATGGCTGCTTTCTGAAGTTGTGGCT
  GTGACACTGACCCTGTTGACAAACTCCTTCCACAGCCAGTGGCTTGATGGTGACGGTGAA
  CTTGGACAGAGTCCCACATCCTTCCTGCTGGTGATAAAACTTCTGGTTTTGATTTTTTGA
  AAGACACTGCTGTGTTCTGGCACGAGCGAGCCCGTTTCTGGGGCTGGTTCTTTTCGAGCT
  GGCGATCTTGCGGGACCAACGATTGGCATCTTCCCTCT
  
• Restriction Sites: Please inquire
• ACCN: NM_000635
• Insert Size: 4000 bp
• OTI Disclaimer: Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
• Product Components: The cDNA clone is shipped in a 2-D bar-coded Matrix tube as dried plasmid DNA. The package also includes 100 pmols of both the corresponding 5' and 3' vector primers in separate vials. Every lot of primer is tested to provide clean sequencing of OriGene TrueClones.
• Reconstitution: 1. Centrifuge at 5,000xg for 5min.
  2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA.
  3. Close the tube and incubate for 10 minutes at room temperature.
  4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom.
  5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C.

Reference Data

• RefSeq: NM_000635.2, NP_000626.2
• RefSeq Size: 4015 bp
• RefSeq ORF: 2172 bp
• Locus ID: 5990
• Cytogenetics: 19p13.3
• Protein Families: Druggable Genome, Transcription Factors
• Gene Summary: 'This gene is a member of the regulatory factor X gene family, which encodes transcription factors that contain a highly-conserved winged helix DNA binding domain. The protein encoded by this gene is structurally related to regulatory factors X1, X3, X4, and X5. It is a transcriptional activator that can bind DNA as a monomer or as a heterodimer with other RFX family members. This protein can bind to cis elements in the promoter of the IL-5 receptor alpha gene. Two transcript variants encoding different isoforms have been described for this gene, and both variants utilize alternative polyadenylation sites. [provided by RefSeq, Jul 2008]'
  Transcript Variant: This variant (1) is the longer transcript and encodes the longer protein (isoform a).