SEMA6D (NM_153617) Human Untagged Clone

CAT#: SC124439

SEMA6D (untagged)-Human sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D (SEMA6D), transcript variant 3


  "NM_153617" in other vectors (6)

Reconstitution Protocol

USD 2,060.00

5 Weeks*

Size
    • 10 ug

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Specifications

Product Data
Type Human Untagged Clone
Tag Tag Free
Symbol SEMA6D
Synonyms FLJ11598; KIAA1479
Vector pCMV6-XL4
E. coli Selection Ampicillin (100 ug/mL)
Mammalian Cell Selection None
Sequence Data
>NCBI ORF sequence for NM_153617, the custom clone sequence may differ by one or more nucleotides


ATGAGGGTCTTCCTGCTTTGTGCCTACATACTGCTGCTGATGGTTTCCCAGTTGAGGGCAGTCAGCTTTC
CTGAAGATGATGAACCCCTTAATACTGTCGACTATCACTATTCAAGGCAATATCCGGTTTTTAGAGGACG
CCCTTCAGGCAATGAATCGCAGCACAGGCTGGACTTTCAGCTGATGTTGAAAATTCGAGACACACTTTAT
ATTGCTGGCAGGGATCAAGTTTATACAGTAAACTTAAATGAAATGCCCAAAACAGAAGTAATACCCAACA
AGAAACTGACATGGCGATCAAGACAACAGGATCGAGAAAACTGTGCTATGAAAGGCAAGCATAAAGATGA
ATGCCACAACTTTATCAAAGTATTTGTTCCAAGAAACGATGAGATGGTTTTTGTTTGTGGTACCAATGCA
TTCAATCCCATGTGTAGATACTACAGGTTGAGTACCTTAGAATATGATGGGGAAGAAATTAGTGGCCTGG
CAAGATGCCCATTTGATGCCAGACAAACCAATGTTGCCCTCTTTGCTGATGGGAAGCTGTATTCTGCCAC
AGTGGCTGACTTCTTGGCCAGCGATGCCGTTATTTATCGAAGCATGGGTGATGGATCTGCCCTTCGCACA
ATAAAATATGATTCCAAATGGATAAAAGAGCCACACTTTCTTCATGCCATAGAATATGGAAACTATGTCT
ATTTCTTCTTTCGAGAAATCGCTGTCGAACATAATAATTTAGGCAAGGCTGTGTATTCCCGCGTGGCCCG
CATATGTAAAAACGACATGGGTGGTTCCCAGCGGGTCCTGGAGAAACACTGGACTTCATTTCTAAAGGCT
CGGCTGAACTGTTCTGTCCCTGGAGATTCGTTTTTCTACTTTGATGTTCTGCAGTCTATTACAGACATAA
TACAAATCAATGGCATCCCCACTGTGGTCGGGGTGTTTACCACGCAGCTCAATAGCATCCCTGGTTCTGC
TGTCTGTGCATTTAGCATGGATGACATTGAAAAAGTATTCAAAGGACGGTTTAAGGAACAGAAAACTCCA
GATTCTGTTTGGACAGCAGTTCCCGAAGACAAAGTGCCAAAGCCAAGGCCTGGCTGTTGTGCAAAACACG
GCCTTGCCGAAGCTTATAAAACCTCCATCGATTTCCCGGATGAAACTCTGTCATTCATCAAATCTCATCC
CCTGATGGACTCTGCCGTTCCACCCATTGCCGATGAGCCCTGGTTCACAAAGACTCGGGTCAGGTACAGA
CTGACGGCCATCTCAGTGGACCATTCAGCCGGACCCTACCAGAACTACACAGTCATCTTTGTTGGCTCTG
AAGCTGGCATGGTACTTAAAGTTCTGGCAAAGACCAGTCCTTTCTCTTTGAACGACAGCGTATTACTGGA
AGAGATTGAAGCCTACAACCATGCAAAGTGCAGTGCTGAGAATGAGGAAGACAAAAAGGTCATCTCATTA
CAGTTGGATAAAGATCACCACGCTTTATATGTGGCGTTCTCTAGCTGCATTATCCGCATCCCCCTCAGTC
GCTGTGAGCGTTATGGATCATGTAAAAAGTCTTGTATTGCATCTCGTGACCCGTATTGTGGCTGGTTAAG
CCAGGGATCCTGTGGTAGAGTGACCCCAGGGATGCTTGCTGAAGGATATGAACAAGACACAGAATTCGGC
AACACAGCTCATCTAGGGGACTGCCATGAAATTTTGCCTACTTCAACTACACCAGATTACAAAATATTTG
GCGGTCCAACATCTGGTGTACGATGGGAAGTCCAGTCTGGAGAGTCCAACCAGATGGTCCACATGAATGT
CCTCATCACCTGTGTCTTTGCTGCTTTTGTTTTGGGGGCATTCATTGCAGGTGTGGCAGTATACTGCTAT
CGAGACATGTTTGTTCGGAAAAACAGAAAGATCCATAAAGATGCAGAGTCCGCCCAGTCATGCACAGACT
CCAGTGGAAGTTTTGCCAAACTGAATGGTCTCTTTGACAGCCCTGTCAAGGAATACCAACAGAATATTGA
TTCTCCTAAACTGTATAGTAACCTGCTAACCAGTCGGAAAGAGCTACCACCCAATGGAGATACTAAATCC
ATGGTAATGGACCATCGAGGGCAACCTCCAGAGTTGGCTGCTCTTCCTACTCCTGAGTCTACACCCGTGC
TTCACCAGAAGACCCTGCAGGCCATGAAGAGCCACTCAGAAAAGGCCCATGGCCATGGAGCTTCAAGGAA
AGAAACCCCTCAGTTTTTTCCGTCTAGTCCGCCACCTCATTCCCCATTAAGTCATGGGCATATCCCCAGT
GCCATTGTTCTTCCAAATGCTACCCATGACTACAACACGTCTTTCTCAAACTCCAATGCTCACAAAGCTG
AAAAGAAGCTTCAAAACATTGATCACCCTCTCACAAAGTCATCCAGTAAGAGAGATCACCGGCGTTCTGT
TGATTCCAGAAATACCCTCAATGATCTCCTGAAGCATCTGAATGACCCAAATAGTAACCCCAAAGCCATC
ATGGGAGACATCCAGATGGCACACCAGAACTTAATGCTGGATCCCATGGGATCGATGTCTGAGGTCCCAC
CTAAAGTCCCTAACCGGGAGGCATCGCTATACTCCCCTCCTTCAACTCTCCCCAGAAATAGCCCAACCAA
GCGAGTGGATGTCCCCACCACTCCTGGAGTCCCAATGACTTCTCTGGAAAGACAAAGAGGTTATCACAAA
AATTCCTCCCAGAGGCACTCTATATCTGCTATGCCTAAAAACTTAAACTCACCAAATGGTGTTTTGTTAT
CCAGACAGCCTAGTATGAACCGTGGAGGATATATGCCCACCCCCACTGGGGCGAAGGTGGACTATATTCA
GGGAACACCAGTGAGTGTTCATCTGCAGCCTTCCCTCTCCAGACAGAGCAGCTACACCAGTAATGGCACT
CTTCCTAGGACGGGACTAAAGAGGACGCCGTCCTTAAAACCTGACGTGCCACCAAAGCCTTCCTTTGTTC
CTCAAACCCCATCTGTCAGACCACTGAACAAATACACATACTAG


>OriGene 5' read for NM_153617 unedited
TATACGACTCACTATAGGGCGGCCGCGATTCGGCACGAGGCCTGACTTCACCTTGGCCCA
CCATGAGGGTCTTCCTGCTTTGTGCCTACATACTGCTGCTGATGGTTTCCCAGTTGAGGG
CAGTCAGCTTTCCTGAAGATGATGAACCCCTTAATACTGTCGACTATCACTATTCAAGGC
AATATCCGGTTTTTAGAGGACGCCCTTCAGGCAATGAATCGCAGCACAGGCTGGACTTTC
AGCTGATGTTGAAAATTCGAGACACACTTTATATTGCTGGCAGGGATCAAGTTTATACAG
TAAACTTAAATGAAATGCCCAAAACAGAAGTAATACCAAACAAGAAACTGACATGGCGAT
CAAGACAACAGGATCGAGAAAACTGTGCTATGAAAGGCAAGCATAAAGATGAATGCCACA
ACTTTATCAAAGTATTTGTTCCAAGAAACGATGAGATGGTTTTTGTTTGTGGTACCAATG
CATTCAATCCCATGTGTAGATACTACAGGTTGAGTACCTTAGAATATGATGGGGAAGAAA
TTAGTGGCCTGGCAAGATGCCCATTTGATGCCAGACAAACCAATGTTGCCCTCTTTGCTG
ATGGGAAGCTGTATTCTGCCACAGTGGCTGACTTCTTGGCCAGCGATGCCCGTATTTATC
GAAGCATGGGTGATGGATTCTGCCCTTTCGCACAATAAAATATGATTCCAAATGGATAAA
AGAGCCCACACTTTTCTTCATGCCATAGAATATGGGANACTATGTCTATTTTTCTTCTTT
CGAGAAAATCGCTGGTCGAACATTATAATNTAAGGCAGGGCTGGGTATTCTCCCGGGTGG
CCCGCATATGTAAAACGACACTGGGTGGGTTCCACCCGGGTCTGGAGAACAACTGGACTT
CATTCTTAAGGCTCGCCTGACCGTTCTGTCCTGAGAATACGTTCTTCTCTTTGAGAGAGG
GCCCA
>OriGene 3' read for NM_153617 unedited
ACACATTGGCGATTGGCAACCTTCCAGGGNCCAGGGTGAGAGCACTGGAGGCAGGGGTAC
ACAGGNGCATGCCACTCCGGGCATCTGTTCAGGAAAACAGCTATGACCGCGGCCGCAATC
TAGAGTCGAGTTTTTTTTTTTTTTTTTTAATGATTTGTATATTTTATTTTGACTTTACAT
GCGGTGTTAAAAACCCAAAGTACATATTATTTACACATCCACAATACAAGTTTACAAGGT
ATCTATTCATGTTAAAGTACTCTATAAAACAGTATAGAGACACTTCACTTGAGGGTTACT
TTTTATGCCGTACCATTAAAAAAGATACAATCTGCGTTTACCTTTGCACAAATGGATAAA
GCATTTAAAAATTAAATTAACAGGATAGAGACTAGATTTAATGTTAGAAATTTCAACATA
AATACTGATTGAACTCACATTACAAACTACAAGGAAGCACAATGTTACAAAATGTTATCT
GGGGTCACATAGAGTTACTGTTCTGTTTTACACACGCTGGGATTAATATTGGTAAGGTGA
ATTCAAACACGTTTGTTGTTGGTGGACTGAGTAGTGTTTATCATTGGTTGGTTTAATTTA
ATAATAAACTGGAATATTTTANTTGCCAAGCTGAAGTGTTTCAAGAACAGAAATTTTAGC
TTTAGCGCTCCCAAAGATCACTGGAAAATCACGTTCTTAATAAAAAAATGTTTCTTAAAA
AAAAAAAAAACTGGGATCAGNTTTCCCCATTACTGTAAAAAAATGATCTTGGTCCTCNGC
AANATGTCCCCCCCCCAAATNNTAGGTCCCCACCGGATTAGCCAAAGAAAACCATTTGAA
ACNCATTTACCTGATTACAGCNNNGGCAAAACCCNGGCGTGGGAATTTACAAGAATGGTT
ACCCAAAAAAGTGAGTGGAGGACANNNAATTNACTGAAAAATGNNCAAAGTTCAAACAAT
T
Restriction Sites NotI-NotI     
ACCN NM_153617
ORF Size 3054 bp
Insert Size 6000
OTI Disclaimer Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP).
Reference Data
RefSeq NM_153617.1, NP_705870.1
RefSeq Size 5941
RefSeq ORF 3054
Locus ID 80031
Protein Families Druggable Genome, Transmembrane
Protein Pathways Axon guidance
Gene Summary Semaphorins are a large family, including both secreted and membrane associated proteins, many of which have been implicated as inhibitors or chemorepellents in axon pathfinding, fasciculation and branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies. Results demonstrate that transmembrane semaphorins, like the secreted ones, can act as repulsive axon guidance cues. This gene encodes a class 6 vertebrate transmembrane semaphorin that demonstrates alternative splicing. Several transcript variants have been identified and expression of the distinct encoded isoforms is thought to be regulated in a tissue- and development-dependent manner. [provided by RefSeq, Nov 2010]
Transcript Variant: This variant (3) lacks an internal exon, compared to variant 4. The encoded isoform (3) is missing an internal segment relative to isoform 4.

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